Auxotyping of Neisseria gonorrhoeae isolated in the United Kingdom.

Abstract:

:One hundred and twenty consecutive isolates of Neisseria gonorrhoeae from the County of Avon, UK, were examined by auxotyping and penicillin susceptibility testing. Requirements for proline (Pro), arginine (Arg), hypoxanthine (Hyp), uracil (Ura) and methionine (Met) were determined with a modified Heckels' medium. Prototrophic strains accounted for 29.9% of isolates and were a heterogeneous group as judged by penicillin susceptibility testing. The group most generally susceptible to penicillin required Arg-Hyp-Ura, and represented 27.5% of isolates. The Pro-Argo-Ura auxogroup (10% of isolates) had the narrowest range of penicillin susceptibility. Prototrophic strains had a reduced growth rate on arginine-free medium. Investigations of this phenomenon and suitable methods for auxotyping are reported.

journal_name

J Med Microbiol

authors

Copley CG,Egglestone SI

doi

10.1099/00222615-16-3-295

subject

Has Abstract

pub_date

1983-08-01 00:00:00

pages

295-302

issue

3

eissn

0022-2615

issn

1473-5644

journal_volume

16

pub_type

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