Liposomal encapsulation augments delayed hypersensitivity reactions to tuberculin proteins.

Abstract:

:Encapsulation of purified tuberculoproteins in liposomes augmented their ability to elicit delayed hypersensitivity reactions in BCG-immune rats. The effect was most marked with a low-molecular-weight tuberculopeptide that was relatively poor at eliciting reactions when in free form. These findings indicate that, in addition to the antigenic nature of the material, the physical form of presentation of mycobacterial test antigens can influence their ability to elicit hypersensitivity reactions.

journal_name

J Med Microbiol

authors

Pimm MV,Baldwin RW

doi

10.1099/00222615-18-3-429

subject

Has Abstract

pub_date

1984-12-01 00:00:00

pages

429-32

issue

3

eissn

0022-2615

issn

1473-5644

journal_volume

18

pub_type

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