Production of extracellular matrix by Candida albicans biofilms.

Abstract:

:Growth of Candida albicans biofilms and production of extracellular matrix were monitored by dry weight, colorimetric and radioisotope assays, and by scanning electron microscopy. Under static incubation conditions synthesis of matrix material was minimal, but increased dramatically when developing biofilms were subjected to a liquid flow with the result that the cells were enveloped in extracellular polymer. These findings suggest that production of matrix material could contribute to the resistance of biofilm cells to antifungal agents in vivo.

journal_name

J Med Microbiol

authors

Hawser SP,Baillie GS,Douglas LJ

doi

10.1099/00222615-47-3-253

subject

Has Abstract

pub_date

1998-03-01 00:00:00

pages

253-6

issue

3

eissn

0022-2615

issn

1473-5644

journal_volume

47

pub_type

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