Abstract:
:Mycobacterium bovis is a pathogen of cattle. The unpasteurized milk of affected cattle is a source of infection in humans. Despite the screening of cattle and the pasteurization of milk, M bovis has not been eradicated. A high index of clinical suspicion is needed in symptomatic patients with a history of possible exposure. At risk groups include animal workers, farmers, meat packers, vets and zoo keepers. Humans are usually infected by the aerosol route. We present two cases of human bovine tuberculosis. One was a presumptive case and the second was a confirmed case. Both responded well to antituberculous therapy. In the confirmed case, there was evidence of transmission to the partner living in the same house. Rifampicin prophylaxis was given to the exposed case. The M. bovis from the confirmed case was isoniazid resistant, in addition to having the well known resistance to pyrazinamide. Isoniazid resistance has been described before in those who are immunocompromised. We describe it in an immunocompetent patient.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Bilal S,Iqbal M,Murphy P,Power Jdoi
10.1099/jmm.0.020511-0subject
Has Abstractpub_date
2010-11-01 00:00:00pages
1379-1382issue
Pt 11eissn
0022-2615issn
1473-5644journal_volume
59pub_type
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