A clinical isolate of Escherichia coli co-harbouring mcr-1 and blaNDM-5 in Japan.

Abstract:

:The mcr-1 gene encodes a phosphoethanolamine transferase, which confers resistance to colistin by transferring phosphoethanolamine to lipid A. This study describes the emergence of a colistin- and carbapenem-resistant clinical isolate of Escherichia coli harbouring mcr-1 and blaNDM-5 genes, located on 90 and 150 Kb plasmids, respectively. The isolate belonged to ST132. This is the first report of a clinical isolate in Japan co-harbouring mcr-1 and blaNDM-5.

journal_name

J Med Microbiol

authors

Uchida H,Tada T,Sugahara Y,Kato A,Miyairi I,Kirikae T

doi

10.1099/jmm.0.000793

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

1047-1049

issue

8

eissn

0022-2615

issn

1473-5644

journal_volume

67

pub_type

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