Human herpesvirus 7.

abstract：:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human respiratory viral infection that has rapidly progressed into a pandemic, causing significant morbidity and mortality. Blood clotting disorders and acute respiratory failure have surfaced as the major complications among the severe cases ...

journal_title：Reviews in medical virology

authors： Pujhari S,Paul S,Ahluwalia J,Rasgon JL

更新日期：2020-10-06 00:00:00

abstract：:Arenaviruses, such as Lassa fever, establish chronic infections in rodents, leading to incidental transmission to humans. Lassa fever is a clinically severe disease, yet the absence of second attacks implies life-long immunity. The aim of this review is to consider whether such immunity could be provided by vaccines. ...

journal_title：Reviews in medical virology

authors： Fisher-Hoch SP,McCormick JB

更新日期：2001-09-01 00:00:00

abstract：:There is a growing appreciation that the regulation of the melatonergic pathways, both pineal and systemic, may be an important aspect in how viruses drive the cellular changes that underpin their control of cellular function. We review the melatonergic pathway role in viral infections, emphasizing influenza and covid...

journal_title：Reviews in medical virology

authors： Anderson G,Reiter RJ

更新日期：2020-05-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a devastating and often fatal demyelinating disease of the central nervous system for which effective therapies are lacking. It is caused by the replication of polyomavirus JC (JCV) in the oligodendrocytes and astrocytes leading to their cytolytic death and loss of m...

journal_title：Reviews in medical virology

authors： White MK,Sariyer IK,Gordon J,Delbue S,Pietropaolo V,Berger JR,Khalili K

更新日期：2016-03-01 00:00:00

abstract：:Infections with the beta-herpesviruses human herpesvirus-6 (HHV-6) and human herpesvirus-7 (HHV-7) are ubiquitous in childhood. The immunosuppression secondary to organ or bone marrow transplantation together with posttransplantation management may favour viral replication and reactivation. HHV-6 and -7 induce immunos...

journal_title：Reviews in medical virology

authors： Dockrell DH,Paya CV

更新日期：2001-01-01 00:00:00

abstract：:Of all the nutrients, vitamin A has been the most extensively evaluated for its impact on immunity. There are three main forms of vitamin A, retinol, retinal and retinoic acid (RA) with the latter being most biologically active and all-trans-RA (ATRA) its main derivative. Vitamin A is a key regulator of the functions ...

journal_title：Reviews in medical virology

authors： Midha IK,Kumar N,Kumar A,Madan T

更新日期：2020-12-31 00:00:00

abstract：:Hepatitis E virus (HEV) is responsible for more than 50% of acute viral hepatitis cases in endemic countries. Approximately 2 billion individuals live in hepatitis E-endemic areas and, therefore, are at risk of infection. According to World Health Organization, HEV causes about 20.1 million infections and 70 000 death...

journal_title：Reviews in medical virology

authors： Pérez-Gracia MT,Suay-García B,Mateos-Lindemann ML

更新日期：2017-05-01 00:00:00

abstract：:While outbreaks of foodborne disease remain an important public health concern, their aetiology is not identified in a majority of instances. In targeted studies, the application of newly developed molecular assays has demonstrated that a large proportion of these outbreaks may be caused by the "Norwalk-like viruses" ...

journal_title：Reviews in medical virology

authors： Parashar UD,Monroe SS

更新日期：2001-07-01 00:00:00

abstract：:Blood-borne viruses, such as hepatitis B virus, hepatitis C virus, human immunodeficiency virus, and the facultative blood-borne hepatitis E virus, are considered a major public health problem given that they are accountable for millions of deaths each year. Treatment options, including effective vaccine design, devel...

journal_title：Reviews in medical virology

authors： Pfaender S,von Hahn T,Steinmann J,Ciesek S,Steinmann E

更新日期：2016-09-01 00:00:00

abstract：AUTHOR CONTRIBUTION:FN performed the literature review and wrote the manuscript; STZ coauthored, edited, and reviewed the manuscript. ABSTRACT:Treatment response in Hepatitis C virus (HCV) has generated varied effects in patients. Recently, nonresponsive and relapse patients related to host and genotype variabilities ...

journal_title：Reviews in medical virology

authors： Fadl N,Salem TZ

更新日期：2020-07-01 00:00:00

abstract：:Invasion of infectious agents through mucosal surfaces can be prevented by use of the common mucosal immune system (CMIS), which interconnects inductive tissues, including Peyer's patches (PPs) and nasopharyngeal-associated lymphoreticular tissue (NALT), and effector tissues of the intestinal and respiratory tracts. I...

journal_title：Reviews in medical virology

authors： Yuki Y,Kiyono H

更新日期：2003-09-01 00:00:00

abstract：:Although the CNS is in part protected from peripheral insults by the blood-brain barrier and the blood-cerebrospinal fluid barrier, a number of human viruses gain access to the brain, replicate within this organ, or sustain latent infection. The efficacy of antiviral drugs towards the cerebral viral load is often limi...

journal_title：Reviews in medical virology

authors： Strazielle N,Ghersi-Egea JF

更新日期：2005-03-01 00:00:00

abstract：:Maternofetal transmission of cytomegalovirus (CMV) is the most common infectious cause of congenital malformation in developed countries. Maternal infection often results from close contact with infected children, and this may occur in day care centres (DCCs). A systematic review of observational studies was conducted...

journal_title：Reviews in medical virology

authors： Zheng QY,Huynh KT,van Zuylen WJ,Craig ME,Rawlinson WD

更新日期：2019-01-01 00:00:00

abstract：:The influenza A virus genome consists of eight segmented, single-stranded, negative-sense RNAs. Each viral RNA (vRNA) segment forms a ribonucleoprotein (RNP) complex together with NPs and a polymerase complex, which is a fundamental unit for transcription and replication of the viral genome. Although the exact structu...

journal_title：Reviews in medical virology

authors： Noda T,Kawaoka Y

更新日期：2010-11-01 00:00:00

abstract：:After the serendipitous discovery of HIV eradication in the "Berlin patient", interest has grown in curing HIV infection by replacing the patient's replication-competent blood cells with infection-resistant ones. At the same time, induced pluripotent stem cell technologies and genetic engineering have boosted cell the...

journal_title：Reviews in medical virology

authors： Focosi D,Maggi F,Ceccherini-Nelli L,Pistello M

更新日期：2015-05-01 00:00:00

abstract：:The orf virus (ORFV) is a zoonotic, epitheliotropic, DNA parapoxvirus that infects principally sheep and goats. Exposure of animals to the virus or immunization by an ORFV preparation can accentuate the severity of disease, which has provoked an interest in the underlying cellular, virological, and molecular mechanism...

journal_title：Reviews in medical virology

authors： Wang R,Wang Y,Liu F,Luo S

更新日期：2019-01-01 00:00:00

abstract：:Vaccination is the current strategy for control and prevention of severe rotavirus infections, a major cause of acute, dehydrating diarrhoea in young children worldwide. Public health interventions aimed at improving water, food and sanitation are unlikely adequately to control the disease. The development of vaccines...

journal_title：Reviews in medical virology

authors： Fischer TK,Gentsch JR

更新日期：2004-03-01 00:00:00

abstract：:Viral replication and spreading are fundamental events in the viral life cycle, accounting for the assembly and egression of nascent virions, events that are directly associated with viral pathogenesis in target hosts. These processes occur in cellular compartments that are modified by specialized viral proteins, caus...

journal_title：Reviews in medical virology

authors： de Armas-Rillo L,Valera MS,Marrero-Hernández S,Valenzuela-Fernández A

更新日期：2016-05-01 00:00:00

abstract：:The serine/threonine kinase expressed by human cytomegalovirus from gene UL97 phosphorylates the antiviral drug ganciclovir, but its biological function is the phosphorylation of its natural viral and cellular protein substrates which affect viral replication at many levels. The UL97 kinase null phenotype is therefore...

journal_title：Reviews in medical virology

authors： Prichard MN

更新日期：2009-07-01 00:00:00

abstract：:The advent of advanced cell culture and cytogenetics techniques in the 1950s opened a new avenue for research on the pathogenic interactions between animal viruses and their hosts. Studies of many viruses revealed their ability to nonspecifically induce cytogenetic damage to their host cell's chromosomes. However, onl...

journal_title：Reviews in medical virology

authors： Fortunato EA,Spector DH

更新日期：2003-01-01 00:00:00

abstract：:Herpes simplex virus type-1 (HSV-1) is among the most common human pathogens worldwide. Its entry into host cells is an intricate process that relies heavily on the ability of the viral glycoproteins to bind host cellular proteins and to efficiently mediate fusion of the virus envelope with the cell membrane. Acquisit...

journal_title：Reviews in medical virology

authors： Antoine TE,Park PJ,Shukla D

更新日期：2013-05-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) infection is the most common cause of bronchiolitis and pneumonia in the pediatric population worldwide. The immunopathology of RSV infection varies considerably and severe disease occurs only in a minority of the population. There are many factors (host, viral, and environmental) tha...

journal_title：Reviews in medical virology

authors： Tahamtan A,Askari FS,Bont L,Salimi V

更新日期：2019-03-01 00:00:00

abstract：:There is a wealth of data supporting the use of viral load measurements to monitor therapy. Indeed, clinical drug trial endpoints routinely include the proportion of patients with a plasma viral load reduction of greater than 0.5 log(10), or greater than 1 log(10). Since a higher viral load reflects increased amounts ...

journal_title：Reviews in medical virology

authors： Pillay D

更新日期：2002-11-01 00:00:00

abstract：:Tat (transactivator of transcription) regulates transcription from the HIV provirus. It plays a crucial role in disease progression, supporting efficient replication of the viral genome. Tat also modulates many functions in the host genome via its interaction with chromatin and proteins. Many of the functions of Tat a...

journal_title：Reviews in medical virology

authors： Kurnaeva MA,Sheval EV,Musinova YR,Vassetzky YS

更新日期：2019-03-01 00:00:00

abstract：:HIV-1 and HIV-2 share many similarities including their basic gene arrangement, modes of transmission, intracellular replication pathways and clinical consequences: both result in AIDS. However, HIV-2 is characterised by lower transmissibility and reduced likelihood of progression to AIDS. The underlying mechanistic d...

journal_title：Reviews in medical virology

authors： Nyamweya S,Hegedus A,Jaye A,Rowland-Jones S,Flanagan KL,Macallan DC

更新日期：2013-07-01 00:00:00

abstract：:Adjuvants historically are considered to stimulate immune responses 'non-specifically'. Recently, a renewed understanding of the critical role of innate immunity in influencing the development of an adaptive immune response has led researchers to a better understanding of 'the adjuvant effect'. Although innate immune ...

journal_title：Reviews in medical virology

authors： Fairweather D,Frisancho-Kiss S,Rose NR

更新日期：2005-01-01 00:00:00

abstract：:Type B coxsackieviruses (CV-B) frequently infect the central nervous system (CNS) causing neurological diseases notably meningitis and encephalitis. These infections occur principally among newborns and children. Epidemiological studies of patients with nervous system disorders demonstrate the presence of infectious v...

journal_title：Reviews in medical virology

authors： Jmii H,Fisson S,Aouni M,Jaidane H

更新日期：2020-11-07 00:00:00

abstract：:The mosquito-borne flavivirus, Japanese encephalitis virus (JEV), is the leading cause of virus-induced encephalitis globally and a major public health concern of several countries in Southeast Asia, with the potential to become a global pathogen. The virus is neurotropic, and the disease ranges from mild fever to sev...

journal_title：Reviews in medical virology

authors： Nain M,Abdin MZ,Kalia M,Vrati S

更新日期：2016-03-01 00:00:00

abstract：:Hepatitis B virus (HBV) is one of the causative agents of hepatocellular carcinoma. The molecular mechanisms of tumorigenesis are complex. One of the host factors involved is apparently the long-lasting inflammatory reaction which accompanies chronic HBV infection. Although HBV lacks a typical viral oncogene, the HBx ...

journal_title：Reviews in medical virology

authors： Niller HH,Ay E,Banati F,Demcsák A,Takacs M,Minarovits J

更新日期：2016-01-01 00:00:00

abstract：:The SCID-hu Thy/Liv mouse is a model for the analysis of human thymopoiesis. It has been constructed by engrafting fragments of human fetal liver and thymus into the immunodeficient C.B-17 scid/scid (SCID) mouse. The resulting 'Thy/Liv' organ promotes long-term differentiation of human T cells. Given the apparently no...

journal_title：Reviews in medical virology

authors： Su L

更新日期：1997-09-01 00:00:00