Hepatitis E and pregnancy: current state.

Abstract:

:Hepatitis E virus (HEV) is responsible for more than 50% of acute viral hepatitis cases in endemic countries. Approximately 2 billion individuals live in hepatitis E-endemic areas and, therefore, are at risk of infection. According to World Health Organization, HEV causes about 20.1 million infections and 70 000 deaths every year. In developing countries with poor sanitation, this disease is transmitted through contaminated water and is associated with large outbreaks, affecting hundreds or thousands of people. In developed countries, autochthonous cases of HEV have been increasingly recognized in the past several years. Hepatitis E virus typically causes an acute, self-limiting illness similar to other acute viral hepatitis, such as hepatitis A or B, with about 0.2% to 1% mortality rate in the general population. However, the course of hepatitis E in pregnancy is different than the mild self-constraining infection described in other populations. During pregnancy, HEV infection can take a fulminant course, resulting in fulminant hepatic failure, membrane rupture, spontaneous abortions, and stillbirths. Studies from various developing countries have shown a high incidence of HEV infection in pregnancy with a significant proportion of pregnant women progressing to fulminant hepatitis with a fatality rate of up to 30%. The present review will highlight new aspects of the HEV infection and pregnancy.

journal_name

Rev Med Virol

authors

Pérez-Gracia MT,Suay-García B,Mateos-Lindemann ML

doi

10.1002/rmv.1929

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

e1929

issue

3

eissn

1052-9276

issn

1099-1654

journal_volume

27

pub_type

杂志文章,评审
  • Comparing HIV-1 and HIV-2 infection: Lessons for viral immunopathogenesis.

    abstract::HIV-1 and HIV-2 share many similarities including their basic gene arrangement, modes of transmission, intracellular replication pathways and clinical consequences: both result in AIDS. However, HIV-2 is characterised by lower transmissibility and reduced likelihood of progression to AIDS. The underlying mechanistic d...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.1739

    authors: Nyamweya S,Hegedus A,Jaye A,Rowland-Jones S,Flanagan KL,Macallan DC

    更新日期:2013-07-01 00:00:00

  • Glycoprotein targeted therapeutics: a new era of anti-herpes simplex virus-1 therapeutics.

    abstract::Herpes simplex virus type-1 (HSV-1) is among the most common human pathogens worldwide. Its entry into host cells is an intricate process that relies heavily on the ability of the viral glycoproteins to bind host cellular proteins and to efficiently mediate fusion of the virus envelope with the cell membrane. Acquisit...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.1740

    authors: Antoine TE,Park PJ,Shukla D

    更新日期:2013-05-01 00:00:00

  • The lungs as anatomical reservoirs of HIV infection.

    abstract::Failure of antiretroviral therapy to eradicate HIV, even in individuals who suppress the virus to undetectable levels, is a consequence of persistent infection in latently infected cells and within anatomical reservoirs. Support for the notion that the lungs are distinct anatomical reservoirs of HIV comes from a spect...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.1772

    authors: Costiniuk CT,Jenabian MA

    更新日期:2014-01-01 00:00:00

  • Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis.

    abstract::Nucleotide sequences from a total of 421 HEV isolates were retrieved from Genbank and analysed. Phylogenetically, HEV was classified into four major genotypes. Genotype 1 was more conserved and classified into five subtypes. The number of genotype 2 sequences was limited but can be classified into two subtypes. Genoty...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.482

    authors: Lu L,Li C,Hagedorn CH

    更新日期:2006-01-01 00:00:00

  • Dengue viruses circulating in Indonesia: A systematic review and phylogenetic analysis of data from five decades.

    abstract::Although epidemiological and molecular epidemiological (serotype, genotype, and lineage information) data are available for several major cities in Indonesia, there is yet to be a comprehensive national study of dengue in Indonesia over time. This study was conducted to provide a comprehensive epidemiology of circulat...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章

    doi:10.1002/rmv.2037

    authors: Harapan H,Michie A,Yohan B,Shu PY,Mudatsir M,Sasmono RT,Imrie A

    更新日期:2019-07-01 00:00:00

  • Anti-HIV adaptive immunity: determinants for viral persistence.

    abstract::The immense difficulty in primary control of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection by adaptive immune responses has been a topic of exceptional importance. CD8+ cytotoxic T lymphocytes (CTLs) do play a central role in primary resolution of viremia, but their potency in vi...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.577

    authors: Yamamoto H,Matano T

    更新日期:2008-09-01 00:00:00

  • Towards a human Lassa fever vaccine.

    abstract::Arenaviruses, such as Lassa fever, establish chronic infections in rodents, leading to incidental transmission to humans. Lassa fever is a clinically severe disease, yet the absence of second attacks implies life-long immunity. The aim of this review is to consider whether such immunity could be provided by vaccines. ...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.329

    authors: Fisher-Hoch SP,McCormick JB

    更新日期:2001-09-01 00:00:00

  • BK polyomavirus diversity-Why viral variation matters.

    abstract::BK polyomavirus (BKPyV or BKV) is a non-enveloped, circular double-stranded DNA virus that may exceed 80% seroprevalence in adults. BKV infection typically occurs during childhood, and the majority of adults are latently infected. While BKV infection is rarely associated with clinical disease in most individuals, in i...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2102

    authors: Blackard JT,Davies SM,Laskin BL

    更新日期:2020-07-01 00:00:00

  • CMV in critically ill patients: pathogen or bystander?

    abstract::Despite broad variability in study populations, methodologies for CMV detection, and analytic methods used, multiple studies have documented frequent CMV infection in non-immunocompromised adults with critical illness due to a variety of causes. Higher rates of CMV infection in studies of seropositive patients suggest...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.664

    authors: Limaye AP,Boeckh M

    更新日期:2010-11-01 00:00:00

  • Prevention strategies for blood-borne viruses-in the Era of vaccines, direct acting antivirals and antiretroviral therapy.

    abstract::Blood-borne viruses, such as hepatitis B virus, hepatitis C virus, human immunodeficiency virus, and the facultative blood-borne hepatitis E virus, are considered a major public health problem given that they are accountable for millions of deaths each year. Treatment options, including effective vaccine design, devel...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.1890

    authors: Pfaender S,von Hahn T,Steinmann J,Ciesek S,Steinmann E

    更新日期:2016-09-01 00:00:00

  • Hepatitis E virus.

    abstract::Hepatitis E virus (HEV) is a positive-stranded RNA virus with a 7.2 kb genome that is capped and polyadenylated. The virus is currently unclassified: the organisation of the genome resembles that of the Caliciviridae but sequence analyses suggest it is more closely related to the Togaviridae. Hepatitis E virus is an e...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.384

    authors: Emerson SU,Purcell RH

    更新日期:2003-05-01 00:00:00

  • Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8.

    abstract::A series of antiviral compounds were examined for their activity against human herpesvirus type 6 (HHV-6), type 7 (HHV-7) and type 8 (HHV-8). They were selected either because they are already approved for clinical use in the treatment of herpesvirus infections (acyclovir, valaciclovir, penciclovir, famciclovir, ganci...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.336

    authors: De Clercq E,Naesens L,De Bolle L,Schols D,Zhang Y,Neyts J

    更新日期:2001-11-01 00:00:00

  • Viral induction of site-specific chromosome damage.

    abstract::The advent of advanced cell culture and cytogenetics techniques in the 1950s opened a new avenue for research on the pathogenic interactions between animal viruses and their hosts. Studies of many viruses revealed their ability to nonspecifically induce cytogenetic damage to their host cell's chromosomes. However, onl...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.368

    authors: Fortunato EA,Spector DH

    更新日期:2003-01-01 00:00:00

  • Tat basic domain: A "Swiss army knife" of HIV-1 Tat?

    abstract::Tat (transactivator of transcription) regulates transcription from the HIV provirus. It plays a crucial role in disease progression, supporting efficient replication of the viral genome. Tat also modulates many functions in the host genome via its interaction with chromatin and proteins. Many of the functions of Tat a...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2031

    authors: Kurnaeva MA,Sheval EV,Musinova YR,Vassetzky YS

    更新日期:2019-03-01 00:00:00

  • Cytomegalovirus infection in day care centres: A systematic review and meta-analysis of prevalence of infection in children.

    abstract::Maternofetal transmission of cytomegalovirus (CMV) is the most common infectious cause of congenital malformation in developed countries. Maternal infection often results from close contact with infected children, and this may occur in day care centres (DCCs). A systematic review of observational studies was conducted...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,meta分析

    doi:10.1002/rmv.2011

    authors: Zheng QY,Huynh KT,van Zuylen WJ,Craig ME,Rawlinson WD

    更新日期:2019-01-01 00:00:00

  • Clinical uses of non-nucleoside reverse transcriptase inhibitors.

    abstract::Three non-nucleoside reverse transcriptase inhibitors (NNRTIs) are currently available for treatment of HIV-1 as part of combination antiretroviral therapy. Oral dosing is administered three times daily for delavirdine (DLV), twice daily for nevirapine (NVP), and once daily for efavirenz (EFV). Rash is a common side e...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/1099-1654(200007/08)10:4<217::aid-rmv279>3

    authors: Harris M,Montaner JS

    更新日期:2000-07-01 00:00:00

  • Persistence of arboviruses and antiviral antibodies in vertebrate hosts: its occurrence and impacts.

    abstract::The recent isolation of West Nile virus from a bird in mid-winter in New York immediately raised, as one of a few explanations, the possibility of long-term persistence of arboviruses in vertebrate hosts. Although it was a highly popular topic for research many years ago, generally it has since been neglected and its ...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.314

    authors: Kuno G

    更新日期:2001-05-01 00:00:00

  • Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir.

    abstract::The serine/threonine kinase expressed by human cytomegalovirus from gene UL97 phosphorylates the antiviral drug ganciclovir, but its biological function is the phosphorylation of its natural viral and cellular protein substrates which affect viral replication at many levels. The UL97 kinase null phenotype is therefore...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.615

    authors: Prichard MN

    更新日期:2009-07-01 00:00:00

  • Human herpesvirus 7.

    abstract::Human herpesvirus 7, reported in 1990 is a lymphotropic member of the betaherpesvirus subfamily of herpesviruses. The virus is highly seroprevalent, primary infection usually occurs during childhood, and it has been associated with cases of exanthem subitum, pityriasis rosea, neurological manifestations and transplant...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1099-1654(199910/12)9:4<245::aid-rmv

    authors: Black JB,Pellett PE

    更新日期:1999-10-01 00:00:00

  • New generation of mucosal adjuvants for the induction of protective immunity.

    abstract::Invasion of infectious agents through mucosal surfaces can be prevented by use of the common mucosal immune system (CMIS), which interconnects inductive tissues, including Peyer's patches (PPs) and nasopharyngeal-associated lymphoreticular tissue (NALT), and effector tissues of the intestinal and respiratory tracts. I...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.398

    authors: Yuki Y,Kiyono H

    更新日期:2003-09-01 00:00:00

  • Systematic screening of viral entry inhibitors using surface plasmon resonance.

    abstract::Viral binding and entry into host cells for various viruses have been studied extensively, yielding a detailed understanding of the overall viral entry process. As cell entry is an essential and requisite process by which a virus initiates infection, it is an attractive target for therapeutic intervention. The advanta...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.1952

    authors: Kumar PKR

    更新日期:2017-11-01 00:00:00

  • Mega doses of retinol: A possible immunomodulation in Covid-19 illness in resource-limited settings.

    abstract::Of all the nutrients, vitamin A has been the most extensively evaluated for its impact on immunity. There are three main forms of vitamin A, retinol, retinal and retinoic acid (RA) with the latter being most biologically active and all-trans-RA (ATRA) its main derivative. Vitamin A is a key regulator of the functions ...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2204

    authors: Midha IK,Kumar N,Kumar A,Madan T

    更新日期:2020-12-31 00:00:00

  • Association of dengue disease severity and blood group: A systematic review and meta-analysis.

    abstract::Dengue disease encompasses various clinical manifestations including dengue fever (DF) and dengue hemorrhagic fever (DHF). In this article, we aimed to systematically review and analyze the association between different blood groups and severity of dengue. We searched nine databases for eligible papers reporting preva...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2147

    authors: Hashan MR,Ghozy S,El-Qushayri AE,Pial RH,Hossain MA,Al Kibria GM

    更新日期:2021-01-01 00:00:00

  • Loop-mediated isothermal amplification (LAMP): An effective molecular point-of-care technique for the rapid diagnosis of coronavirus SARS-CoV-2.

    abstract::The novel coronavirus disease-2019 (Covid-19) public health emergency has caused enormous loss around the world. This pandemic is a concrete example of the existing gap between availability of advanced diagnostics and current need for cost-effective methodology. The advent of the loop-mediated isothermal amplification...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2215

    authors: Chaouch M

    更新日期:2021-01-21 00:00:00

  • The dawn of phage therapy.

    abstract::Bacteriophages or phages, being the most abundant entities on earth, represent a potential solution to a diverse range of problems. Phages are successful antibacterial agents whose use in therapeutics was hindered by the discovery of antibiotics. Eventually, because of the development and spread of antibiotic resistan...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2041

    authors: Rehman S,Ali Z,Khan M,Bostan N,Naseem S

    更新日期:2019-07-01 00:00:00

  • Alternative clinical specimens for the detection of SARS-CoV-2: A rapid review.

    abstract::The collection of nasopharyngeal swabs to test for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an invasive technique with implications for patients and clinicians. Alternative clinical specimens from the upper respiratory tract may offer benefits in terms of collection, comfort and ...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2185

    authors: Comber L,Walsh KA,Jordan K,O'Brien KK,Clyne B,Teljeur C,Drummond L,Carty PG,De Gascun CF,Smith SM,Harrington P,Ryan M,O'Neill M

    更新日期:2020-10-22 00:00:00

  • Herpes simplex virus and varicella-zoster virus: why do these human alphaherpesviruses behave so differently from one another?

    abstract::Members of the Herpesviridae family of viruses are classified into the alpha, beta and gamma subfamilies. The alpha subfamily is estimated to have diverged from the beta and gamma subfamilies 200-220 million years ago. The ancestors of the herpes simplex virus (HSV) and the varicella-zoster virus (VZV), two ubiquitous...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.478

    authors: Mori I,Nishiyama Y

    更新日期:2005-11-01 00:00:00

  • Type B coxsackieviruses and central nervous system disorders: critical review of reported associations.

    abstract::Type B coxsackieviruses (CV-B) frequently infect the central nervous system (CNS) causing neurological diseases notably meningitis and encephalitis. These infections occur principally among newborns and children. Epidemiological studies of patients with nervous system disorders demonstrate the presence of infectious v...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章

    doi:10.1002/rmv.2191

    authors: Jmii H,Fisson S,Aouni M,Jaidane H

    更新日期:2020-11-07 00:00:00

  • Viruses as adjuvants for autoimmunity: evidence from Coxsackievirus-induced myocarditis.

    abstract::Adjuvants historically are considered to stimulate immune responses 'non-specifically'. Recently, a renewed understanding of the critical role of innate immunity in influencing the development of an adaptive immune response has led researchers to a better understanding of 'the adjuvant effect'. Although innate immune ...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.445

    authors: Fairweather D,Frisancho-Kiss S,Rose NR

    更新日期:2005-01-01 00:00:00

  • Melatonin: Roles in influenza, Covid-19, and other viral infections.

    abstract::There is a growing appreciation that the regulation of the melatonergic pathways, both pineal and systemic, may be an important aspect in how viruses drive the cellular changes that underpin their control of cellular function. We review the melatonergic pathway role in viral infections, emphasizing influenza and covid...

    journal_title:Reviews in medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/rmv.2109

    authors: Anderson G,Reiter RJ

    更新日期:2020-05-01 00:00:00