Abstract:
:Viral replication and spreading are fundamental events in the viral life cycle, accounting for the assembly and egression of nascent virions, events that are directly associated with viral pathogenesis in target hosts. These processes occur in cellular compartments that are modified by specialized viral proteins, causing a rearrangement of different cell membranes in infected cells and affecting the ER, mitochondria, Golgi apparatus, vesicles and endosomes, as well as processes such as autophagic membrane flux. In fact, the activation or inhibition of membrane trafficking and other related activities are fundamental to ensure the adequate replication and spreading of certain viruses. In this review, data will be presented that support the key role of membrane dynamics in the viral cycle, especially in terms of the assembly, egression and infection processes. By defining how viruses orchestrate these events it will be possible to understand how they successfully complete their route of infection, establishing viral pathogenesis and provoking disease.
journal_name
Rev Med Viroljournal_title
Reviews in medical virologyauthors
de Armas-Rillo L,Valera MS,Marrero-Hernández S,Valenzuela-Fernández Adoi
10.1002/rmv.1872subject
Has Abstractpub_date
2016-05-01 00:00:00pages
146-60issue
3eissn
1052-9276issn
1099-1654journal_volume
26pub_type
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journal_title:Reviews in medical virology
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章
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journal_title:Reviews in medical virology
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1002/rmv.2177
更新日期:2020-10-06 00:00:00
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journal_title:Reviews in medical virology
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更新日期:2001-09-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
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更新日期:2006-05-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.2204
更新日期:2020-12-31 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.1725
更新日期:2013-03-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.1831
更新日期:2015-05-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.314
更新日期:2001-05-01 00:00:00
abstract::Viruses are obligate parasites dependent on host cells for survival. Viral infection of a cell activates a panel of pattern recognition receptors that mediate antiviral host responses to inhibit viral replication and dissemination. Viruses have evolved mechanisms to evade and subvert this antiviral host response, incl...
journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.1892
更新日期:2016-09-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.1866
更新日期:2016-03-01 00:00:00
abstract::Nucleotide sequences from a total of 421 HEV isolates were retrieved from Genbank and analysed. Phylogenetically, HEV was classified into four major genotypes. Genotype 1 was more conserved and classified into five subtypes. The number of genotype 2 sequences was limited but can be classified into two subtypes. Genoty...
journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.482
更新日期:2006-01-01 00:00:00
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journal_title:Reviews in medical virology
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
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更新日期:2005-09-01 00:00:00
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journal_title:Reviews in medical virology
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更新日期:2009-07-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
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更新日期:2002-11-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章,评审
doi:10.1002/rmv.2187
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更新日期:2019-03-01 00:00:00
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journal_title:Reviews in medical virology
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journal_title:Reviews in medical virology
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更新日期:2015-01-01 00:00:00
abstract::The influenza A virus genome consists of eight segmented, single-stranded, negative-sense RNAs. Each viral RNA (vRNA) segment forms a ribonucleoprotein (RNP) complex together with NPs and a polymerase complex, which is a fundamental unit for transcription and replication of the viral genome. Although the exact structu...
journal_title:Reviews in medical virology
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更新日期:2010-11-01 00:00:00
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journal_title:Reviews in medical virology
pub_type: 杂志文章
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更新日期:1998-10-01 00:00:00