Abstract:
: After the introduction of highly active antiretroviral therapies (HAART), an increased incidence of insulin resistance, diabetes mellitus (DM), and cardiovascular diseases has been described. The impact of such conditions on mortality in the post-HAART era has been also assessed in various modes in the literature. In this paper, we report on the death risks for DM, myocardial infarction, and chronic ischemic heart diseases that were investigated among 9662 Italian AIDS cases diagnosed between 1999 and 2005. Death certificates reporting DM, myocardial infarction, and chronic ischemic heart diseases were reviewed to identify the underlying cause of death, and to compare the observed numbers of deaths with the expected ones from the sex- and age-matched, general population of Italy. Person-years at risk of death were computed from date of AIDS diagnosis up to date of death or to December 31, 2006. Standardized mortality ratios (SMR) and their 95% confidence intervals (CI) were computed. DM and cardiovascular diseases were the cause of death for 43 out of 3101 deceased AIDS cases (i.e., 1.4% of all deaths). In comparison with the general population, the risks of death were 6.4-fold higher for DM (95% CI:3.5-10.8), 2.3-fold higher for myocardial infarction (95% CI:1.4-3.7) and 3.0 for chronic ischemic heart diseases (95% CI: 1.5-5.2).
journal_name
AIDS Res Therjournal_title
AIDS research and therapyauthors
Serraino D,Bruzzone S,Zucchetto A,Suligoi B,De Paoli A,Pennazza S,Camoni L,Dal Maso L,De Paoli P,Rezza Gdoi
10.1186/1742-6405-7-11subject
Has Abstractpub_date
2010-05-24 00:00:00pages
11issn
1742-6405pii
1742-6405-7-11journal_volume
7pub_type
杂志文章abstract:BACKGROUND:Highly active antiretroviral therapy (HAART) improves the immune function and decreases morbidity, mortality and opportunistic infections (OIs) in HIV-infected patients. However, since the use of HAART, immune restoration disease (IRD) has been described in association with many OIs. Our objective was to det...
journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/1742-6405-7-46
更新日期:2010-12-21 00:00:00
abstract:BACKGROUND:People who inject drugs (PWID) living with HIV often experience sub-optimal antiretroviral therapy (ART) treatment outcomes, including HIV plasma viral load (PVL) rebound. While previous studies have identified risk factors for PVL rebound among PWID, no study has examined the perspectives of PWID who have e...
journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/s12981-016-0108-9
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journal_title:AIDS research and therapy
pub_type: 杂志文章,评审
doi:10.1186/s12981-017-0177-4
更新日期:2017-09-12 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/1742-6405-4-10
更新日期:2007-05-12 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/s12981-015-0058-7
更新日期:2015-05-10 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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journal_title:AIDS research and therapy
pub_type: 杂志文章,随机对照试验
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更新日期:2019-02-22 00:00:00
abstract:BACKGROUND:To describe the development and the psychometric properties of the Istituto Superiore di Sanità-HIV symptoms scale (lSS-HIV symptoms scale). METHODS:The ISS-HIV symptom scale was developed by an Italian working team including researchers, physicians and people living with HIV. The development process went t...
journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/s12981-016-0102-2
更新日期:2016-04-09 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/1742-6405-3-16
更新日期:2006-05-26 00:00:00
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journal_title:AIDS research and therapy
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/s12981-019-0245-z
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pub_type: 杂志文章
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更新日期:2015-03-21 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/s12981-015-0076-5
更新日期:2015-10-06 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/1742-6405-4-16
更新日期:2007-07-16 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/s12981-017-0146-y
更新日期:2017-04-11 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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更新日期:2017-03-28 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/1742-6405-2-1
更新日期:2005-01-13 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
doi:10.1186/1742-6405-4-15
更新日期:2007-07-09 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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更新日期:2010-07-23 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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更新日期:2011-03-01 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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更新日期:2011-05-12 00:00:00
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journal_title:AIDS research and therapy
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更新日期:2016-11-15 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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更新日期:2008-01-29 00:00:00
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pub_type: 杂志文章
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更新日期:2007-06-06 00:00:00
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更新日期:2019-11-19 00:00:00
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更新日期:2014-07-01 00:00:00
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journal_title:AIDS research and therapy
pub_type: 杂志文章
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journal_title:AIDS research and therapy
pub_type: 杂志文章,评审
doi:10.1186/s12981-017-0173-8
更新日期:2017-09-12 00:00:00
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journal_title:AIDS research and therapy
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doi:10.1186/1742-6405-7-21
更新日期:2010-07-06 00:00:00