Factors related to NT-proBNP levels in HIV patients aged over 40 years.

abstract：: In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred during a phase of uncontrolled viral replication combined with a severe immunodeficiency and resolved by an effect...

journal_title：AIDS research and therapy

authors： Esposito A,Conti V,Cagliuso M,Pastori D,Fantauzzi A,Mezzaroma I

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Separately, chronic alcohol ingestion and HIV-1 infection are associated with severe skeletal muscle derangements, including atrophy and wasting, weakness, and fatigue. One prospective cohort study reported that 41% of HIV-infected patients met the criteria for alcoholism, however; few reports exist on the c...

journal_title：AIDS research and therapy

authors： Clary CR,Guidot DM,Bratina MA,Otis JS

更新日期：2011-08-16 00:00:00

abstract：BACKGROUND:Most in vitro assays of drug potency may not adequately predict the performance in vivo. Methods to assess the persistence of antiviral activity of deoxynucleoside analogs, which require intracellular activation to the active metabolites that can persist in cells, will be important for designing dosages, com...

journal_title：AIDS research and therapy

authors： Paintsil E,Grill SP,Dutschman GE,Cheng YC

更新日期：2009-04-22 00:00:00

abstract：BACKGROUND:Moringa oleifera Lam., an herb commonly consumed by HIV-infected people on antiretroviral therapy, inhibits cytochrome P450 3A4, 1A2 and 2D6 activity in vitro; and may alter the pharmacokinetics (PK) of antiretroviral drugs metabolized via the same pathways. However, in vitro drug interaction activity may no...

journal_title：AIDS research and therapy

authors： Monera-Penduka TG,Maponga CC,Wolfe AR,Wiesner L,Morse GD,Nhachi CF

更新日期：2017-03-14 00:00:00

abstract：BACKGROUND:The search for disease biomarkers within human peripheral fluids has become a favorable approach to preventative therapeutics throughout the past few years. The comparison of normal versus disease states can identify an overexpression or a suppression of critical proteins where illness has directly altered a...

journal_title：AIDS research and therapy

authors： Van Duyne R,Guendel I,Kehn-Hall K,Easley R,Klase Z,Liu C,Young M,Kashanchi F

更新日期：2010-07-06 00:00:00

abstract：BACKGROUND:Community-drug distribution point is a care model for stable patients in the community designed to make ART delivery more efficient for the health system and provide appropriate support to encourage long-term retention of patients. We examined program retention among ART program participants in rural Uganda,...

journal_title：AIDS research and therapy

authors： Okoboi S,Ding E,Persuad S,Wangisi J,Birungi J,Shurgold S,Kato D,Nyonyintono M,Egessa A,Bakanda C,Munderi P,Kaleebu P,Moore DM

更新日期：2015-11-12 00:00:00

abstract：BACKGROUND:Varicella-zoster virus (VZV) reactivation is common but difficult to predict in HIV-infected persons. OBJECTIVE:Since qualitative VZV antibodies can determine past VZV disease or vaccination, we evaluated whether quantitative VZV antibody levels over time can predict future zoster. STUDY DESIGN:US Military...

journal_title：AIDS research and therapy

authors： Pomerantz HS,Xu X,White J,Sunil TS,Deiss RG,Ganesan A,Agan BK,Okulicz JF

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:In many countries in Asia, the HIV epidemic is in a concentrated phase, with high prevalence in certain risk groups, such as men who inject drugs. There is also a rapid increase of HIV among women. The latter might be due to high levels of sero-discordant couples and increasing transmission from male to fema...

journal_title：AIDS research and therapy

authors： Van Tam V,Cuong DD,Alfven T,Phuc HD,Chuc NT,Hoa NP,Diwan V,Larsson M

更新日期：2016-11-15 00:00:00

abstract：:High rates of non-nucleoside reverse transcriptase inhibitors (NNRTI) resistance was a key consideration in the WHO policies transitioning first-line regimens to include integrase inhibitors (dolutegravir [DTG]). However, recent data suggests a relationship between DTG and neural tube defects among women exposed durin...

journal_title：AIDS research and therapy

authors： Rutstein SE,Chen JS,Nelson JAE,Phiri S,Miller WC,Hosseinipour MC

更新日期：2019-02-22 00:00:00

abstract：BACKGROUND:HLA-B*57:01 screening was added to clinical care guidelines in 2008 to reduce the risk of hypersensitivity reaction from abacavir. The uptake of HLA-B*57:01 screening and incidence of hypersensitivity reaction were assessed in a prospective clinical cohort in the United States to evaluate the effectiveness o...

journal_title：AIDS research and therapy

authors： Mounzer K,Hsu R,Fusco JS,Brunet L,Henegar CE,Vannappagari V,Stainsby CM,Shaefer MS,Ragone L,Fusco GP

更新日期：2019-01-16 00:00:00

abstract：BACKGROUND:Identifying those at increased risk of death during TB treatment is a priority in resource-constrained settings. We performed this study to determine predictors of mortality during TB treatment. METHODS:We performed a retrospective analysis of a TB surveillance population in a high HIV prevalence area that ...

journal_title：AIDS research and therapy

authors： Pepper DJ,Schomaker M,Wilkinson RJ,de Azevedo V,Maartens G

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Antiretroviral therapy (ART) has modified the natural history of HIV-infection: the incidence of opportunistic infections (OIs) has decreased and mortality associated to HIV has improved dramatically. The reasons for hospitalization have changed; OIs are no longer the most common reason for admission. This s...

journal_title：AIDS research and therapy

authors： Álvarez Barreneche MF,Restrepo Castro CA,Hidrón Botero A,Villa Franco JP,Trompa Romero IM,Restrepo Carvajal L,Eusse García A,Ocampo Mesa A,Echeverri Toro LM,Porras Fernández de Castro GP,Ramírez Rivera JM,Agudelo Restrepo CA

更新日期：2017-11-13 00:00:00

abstract：PURPOSE:We studied the safety, tolerability, virologic, and immunologic effects of mycophenolate mofetil (MMF) added to a stable antiretroviral therapy (ART) in the setting of low-level viremia. METHODS:MMF 500 mg BID or placebo was given to patients thought to be adherent on stable ART with plasma viremia between 200...

journal_title：AIDS research and therapy

authors： Kaur R,Bedimo R,Kvanli MB,Turner D,Shaw L,Margolis D

更新日期：2006-05-26 00:00:00

abstract：BACKGROUND:Practical screening strategies are necessary to detect neurocognitive impairment of all severities in HIV populations, which remains prevalent despite highly active antiretroviral therapy and requires full neuropsychological testing for diagnosis. We aimed to develop a brief and clinically feasible battery t...

journal_title：AIDS research and therapy

authors： Chan LG,Ho MJ,Lin YC,Ong Y,Wong CS

更新日期：2019-04-15 00:00:00

abstract：:Despite the significant success of combination anti-retroviral therapy to reduce HIV viremia and save lives, HIV-1 infection remains a lifelong infection that must be appropriately managed. Advances in the understanding of the HIV infection process and insights from vaccine development in other biomedical fields such ...

journal_title：AIDS research and therapy

authors： Pankrac J,Klein K,Mann JFS

更新日期：2017-09-12 00:00:00

abstract：BACKGROUND:People who inject drugs (PWID) living with HIV often experience sub-optimal antiretroviral therapy (ART) treatment outcomes, including HIV plasma viral load (PVL) rebound. While previous studies have identified risk factors for PVL rebound among PWID, no study has examined the perspectives of PWID who have e...

journal_title：AIDS research and therapy

authors： Small W,Milloy MJ,McNeil R,Maher L,Kerr T

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:About 13 years since the introduction of antiretroviral therapy (ART) for children living with HIV (CLHIV) in Zambia, HIV/AIDS testing and treatment guidelines for children have evolved over the years with limited documentation of long-term trends in the numbers testing HIV positive and initiating ART. We ex...

journal_title：AIDS research and therapy

authors： Munthali T,Michelo C,Mee P,Moyo C,Kashoka A,Liswaniso L,Chiboma I,Todd J

更新日期：2020-05-14 00:00:00

abstract：:HIV-1 infects gut associated lymphoid tissues (GALT) very early after transmission by multiple routes. The infected GALT consequently serves as the major reservoir for HIV-1 infection and could constantly shed HIV-1 and CD4+ T cells into the intestinal lumen. To examine this hypothesis, we monitored HIV-1 RNA/DNA and ...

journal_title：AIDS research and therapy

authors： Chakrabarti AK,Caruso L,Ding M,Shen C,Buchanan W,Gupta P,Rinaldo CR,Chen Y

更新日期：2009-10-02 00:00:00

abstract：BACKGROUND:HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission. METHODS:We modeled two scenarios to measure the impact of adult ART use on the incidence of orphanhood ...

journal_title：AIDS research and therapy

authors： Anema A,Au-Yeung CG,Joffres M,Kaida A,Vasarhelyi K,Kanters S,Montaner JS,Hogg RS

更新日期：2011-03-07 00:00:00

abstract：OBJECTIVE:Recent studies have shown that the current guidelines suggesting immunologic monitoring to determine response to highly active antiretroviral therapy (HAART) are inadequate. We assessed whether routinely collected clinical markers could improve prediction of concurrent HIV RNA levels. METHODS:We included ind...

journal_title：AIDS research and therapy

authors： Lau B,Chander G,Gange SJ,Moore RD

更新日期：2010-07-23 00:00:00

abstract：BACKGROUND:Although highly active antiretroviral therapy (HAART) reduces mortality in the developed world, it remains undocumented in resource-poor settings. We assessed the effect of HAART on patient mortality and tuberculosis incidence rate under routine clinical care conditions in Ethiopia. The objective of this stu...

journal_title：AIDS research and therapy

authors： Jerene D,Naess A,Lindtjørn B

更新日期：2006-04-07 00:00:00

abstract：BACKGROUND:Vitamin D is an important determinant of bone health and also plays a major role in the regulation of the immune system. Interestingly, vitamin D status before the start of highly active antiretroviral therapy (HAART) has been recently associated with HIV disease progression and overall mortality in HIV-posi...

journal_title：AIDS research and therapy

authors： Conesa-Botella A,Florence E,Lynen L,Colebunders R,Menten J,Moreno-Reyes R

更新日期：2010-11-23 00:00:00

abstract：BACKGROUND:Drug resistance testing before initiation of, or during, antiretroviral therapy (ART) is not routinely performed in resource-limited settings. High levels of viral resistance circulating within the population will have impact on treatment programs by increasing the chances of transmission of resistant strain...

journal_title：AIDS research and therapy

authors： Bansode VB,Travers SA,Crampin AC,Ngwira B,French N,Glynn JR,McCormack GP

更新日期：2011-10-13 00:00:00

abstract：: After the introduction of highly active antiretroviral therapies (HAART), an increased incidence of insulin resistance, diabetes mellitus (DM), and cardiovascular diseases has been described. The impact of such conditions on mortality in the post-HAART era has been also assessed in various modes in the literature. In...

journal_title：AIDS research and therapy

authors： Serraino D,Bruzzone S,Zucchetto A,Suligoi B,De Paoli A,Pennazza S,Camoni L,Dal Maso L,De Paoli P,Rezza G

更新日期：2010-05-24 00:00:00

abstract：UNLABELLED: OBJECTIVE:To investigate anti-infective treatments in HIV-infected surgical patients during the perioperative period. METHODS:A retrospective study of sepsis and surgical site infections (SSIs) was conducted in 266 HIV-infected patients. The patients were divided into 3 groups based on CD4+ T cells counts...

journal_title：AIDS research and therapy

authors： Liu B,Zhang L,Guo R,Su J,Li L,Si Y

更新日期：2012-11-27 00:00:00

abstract：: The December 2011 5th International Workshop on HIV Persistence during Therapy addressed the issue of HIV persistence among 210 scientists from 10 countries involved in the study of HIV reservoirs and the search of an HIV cure. High quality abstracts were selected and discussed as oral or poster presentations. The ai...

journal_title：AIDS research and therapy

authors： Stevenson M,Chomont N,Lafeuillade A

更新日期：2012-03-12 00:00:00

abstract：:Intracellular levels of glutathione are depleted in patients with acquired immunodeficiency syndrome in whom the risk of tuberculosis, particularly disseminated disease is many times that of healthy individuals. In this study, we examined the role of glutathione in immunity against tuberculosis infection in samples de...

journal_title：AIDS research and therapy

authors： Venketaraman V,Rodgers T,Linares R,Reilly N,Swaminathan S,Hom D,Millman AC,Wallis R,Connell ND

更新日期：2006-02-20 00:00:00

abstract：BACKGROUND:Voriconazole is metabolized by cytochrome P450 (CYP) 2C19 and CYP 3A4. Drug-drug interactions and genetic polymorphisms modulate their activities. CASE PRESENTATION:A 35-year old African female patient with resistant HIV and a cerebral mass of unknown origin was treated with voriconazole for a suspicion of ...

journal_title：AIDS research and therapy

authors： Bouatou Y,Samer CF,Ing Lorenzini KR,Daali Y,Daou S,Fathi M,Rebsamen M,Desmeules J,Calmy A,Escher M

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:The high rate of HIV-1 mutation and increasing resistance to currently available antiretroviral (ART) therapies highlight the need for new antiviral agents. Products derived from natural sources have been shown to inhibit HIV-1 replication during various stages of the virus life cycle, and therefore represen...

journal_title：AIDS research and therapy

authors： Paskaleva EE,Lin X,Li W,Cotter R,Klein MT,Roberge E,Yu EK,Clark B,Veille JC,Liu Y,Lee DY,Canki M

更新日期：2006-05-25 00:00:00

abstract：BACKGROUND:People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adherence and retention in early HIV care in PHIV in a south Florida hospital-based clinic. METHODS:ART-n...

journal_title：AIDS research and therapy

authors： Sherman EM,Niu J,Elrod S,Clauson KA,Alkhateeb F,Eckardt P

更新日期：2020-05-13 00:00:00