The genomic diversity and phylogenetic relationship in the family iridoviridae.

Abstract:

:The Iridoviridae family are large viruses (∼120-200 nm) that contain a linear double-stranded DNA genome. The genomic size of Iridoviridae family members range from 105,903 bases encoding 97 open reading frames (ORFs) for frog virus 3 to 212,482 bases encoding 211 ORFs for Chilo iridescent virus. The family Iridoviridae is currently subdivided into five genera: Chloriridovirus, Iridovirus, Lymphocystivirus, Megalocytivirus, and Ranavirus. Iridoviruses have been found to infect invertebrates and poikilothermic vertebrates, including amphibians, reptiles, and fish. With such a diverse array of hosts, there is great diversity in gene content between different genera. To understand the origin of iridoviruses, we explored the phylogenetic relationship between individual iridoviruses and defined the core-set of genes shared by all members of the family. In order to further explore the evolutionary relationship between the Iridoviridae family repetitive sequences were identified and compared. Each genome was found to contain a set of unique repetitive sequences that could be used in future virus identification. Repeats common to more than one virus were also identified and changes in copy number between these repeats may provide a simple method to differentiate between very closely related virus strains. The results of this paper will be useful in identifying new iridoviruses and determining their relationship to other members of the family.

journal_name

Viruses

journal_title

Viruses

authors

Eaton HE,Ring BA,Brunetti CR

doi

10.3390/v2071458

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

1458-75

issue

7

issn

1999-4915

pii

viruses-02-01458

journal_volume

2

pub_type

杂志文章
  • Surf and turf: mechanism of enhanced virus spread during poxvirus infection.

    abstract::Commentary on Doceul, V.; Hollinshead, M.; van der Linden, L.; Smith, G.L. Repulsion of superinfecting virions: a mechanism for rapid virus spread. Science2010, 327, 873-876. ...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v2051050

    authors: Condit RC

    更新日期:2010-05-01 00:00:00

  • DWV-A Lethal to Honey Bees (Apis mellifera): A Colony Level Survey of DWV Variants (A, B, and C) in England, Wales, and 32 States across the US.

    abstract::The strong association between Varroa destructor, deformed wing virus (DWV), and high overwintering colony losses (OCL) of honey bees is well established. Three DWV master variants (DWV-A, -B, and -C) have been described, and their role in colony mortality remains an open question. Therefore, the aim of this study is ...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11050426

    authors: Kevill JL,de Souza FS,Sharples C,Oliver R,Schroeder DC,Martin SJ

    更新日期:2019-05-09 00:00:00

  • A filtration based technique for simultaneous SEM and TEM sample preparation for the rapid detection of pathogens.

    abstract::Diagnostic electron microscopy for infectious diseases has the advantage that "everything" in the specimen can be observed, without a priori knowledge of the likely identity of the microorganisms present in the sample. The classical specimen preparation method used employs a droplet of sample, which allows particles t...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v6093458

    authors: Beniac DR,Siemens CG,Wright CJ,Booth TF

    更新日期:2014-09-19 00:00:00

  • The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice.

    abstract::Iminosugars that are competitive inhibitors of endoplasmic reticulum (ER) α-glucosidases have been demonstrated to have antiviral activity against a diverse set of viruses. A novel iminosugar, UV-4B, has recently been shown to provide protection against lethal infections with dengue and influenza A (H1N1) viruses in m...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v8030071

    authors: Warfield KL,Barnard DL,Enterlein SG,Smee DF,Khaliq M,Sampath A,Callahan MV,Ramstedt U,Day CW

    更新日期:2016-03-07 00:00:00

  • Origin of XMRV and its demise as a human pathogen associated with chronic fatigue syndrome.

    abstract::Retroviruses are well known pathogens of mammals, birds and fish. Their potential to induce cancer in chickens was already described almost 100 years ago and murine retroviruses have been a subject of study for 50 years. The first human retroviruses, HTLV and HIV, were discovered more than 30 years ago, surprising res...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v3081312

    authors: Hohn O,Bannert N

    更新日期:2011-08-01 00:00:00

  • Coxsackievirus B4 Can Infect Human Peripheral Blood-Derived Macrophages.

    abstract::Beyond acute infections, group B coxsackieviruses (CVB) are also reported to play a role in the development of chronic diseases, like type 1 diabetes. The viral pathogenesis mainly relies on the interplay between the viruses and innate immune response in genetically-susceptible individuals. We investigated the interac...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v7112924

    authors: Alidjinou EK,Sané F,Trauet J,Copin MC,Hober D

    更新日期:2015-11-24 00:00:00

  • HIV-1 replication and the cellular eukaryotic translation apparatus.

    abstract::Eukaryotic translation is a complex process composed of three main steps: initiation, elongation, and termination. During infections by RNA- and DNA-viruses, the eukaryotic translation machinery is used to assure optimal viral protein synthesis. Human immunodeficiency virus type I (HIV-1) uses several non-canonical pa...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v7010199

    authors: Guerrero S,Batisse J,Libre C,Bernacchi S,Marquet R,Paillart JC

    更新日期:2015-01-19 00:00:00

  • Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer.

    abstract::Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular evolution of peptide-displayed libraries in mammalian model systems, using in vivo phage di...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11110988

    authors: Gillespie JW,Yang L,De Plano LM,Stackhouse MA,Petrenko VA

    更新日期:2019-10-26 00:00:00

  • Comparative Analysis of Different Serological and Molecular Tests for the Detection of Small Ruminant Lentiviruses (SRLVs) in Belgian Sheep and Goats.

    abstract::Countries rely on good diagnostic tests and appropriate testing schemes to fight against economically important small ruminant lentivirus (SRLV) infections. We undertook an extensive comparative analysis of seven commercially available serological tests and one in-house real-time PCR (qPCR) detecting genotype A and B ...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10120696

    authors: Michiels R,Van Mael E,Quinet C,Adjadj NR,Cay AB,De Regge N

    更新日期:2018-12-08 00:00:00

  • Human Coronavirus Infections in Israel: Epidemiology, Clinical Symptoms and Summer Seasonality of HCoV-HKU1.

    abstract::Human coronaviruses (HCoVs) cause mild to severe respiratory diseases. Six types of HCoVs have been discovered, the most recent one termed the Middle East respiratory syndrome coronavirus (MERS-CoV). The aim of this study is to monitor the circulation of HCoV types in the population during 2015⁻2016 in Israel. HCoVs w...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10100515

    authors: Friedman N,Alter H,Hindiyeh M,Mendelson E,Shemer Avni Y,Mandelboim M

    更新日期:2018-09-21 00:00:00

  • Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells.

    abstract::Antigen-specific T lymphocytes play a critical role in controlling viral infections. However, we report here that preexisting virus-specific T cell responses also contribute to promoting adenovirus (Ad) infection. Previously, we found that CD14+ monocytes from Ad-seropositive individuals exhibited an increased suscept...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11020154

    authors: Feng F,Zhao J,Li P,Li R,Chen L,Sun C

    更新日期:2019-02-13 00:00:00

  • Following in the Footsteps of the Chikungunya Virus in Brazil: The First Autochthonous Cases in Amapá in 2014 and Its Emergence in Rio de Janeiro during 2016.

    abstract::Currently, Brazil lives a triple arboviruses epidemic (DENV, ZIKV and CHIKV) making the differential diagnosis difficult for health professionals. Here, we aimed to investigate chikungunya cases and the possible occurrence of co-infections during the epidemic in Amapá (AP) that started in 2014 when the first autochtho...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10110623

    authors: de Souza TMA,Ribeiro ED,Corrêa VCE,Damasco PV,Santos CC,de Bruycker-Nogueira F,Chouin-Carneiro T,Faria NRDC,Nunes PCG,Heringer M,Lima MDRQ,Badolato-Corrêa J,Cipitelli MDC,Azeredo EL,Nogueira RMR,Dos Santos FB

    更新日期:2018-11-12 00:00:00

  • Biomarkers of Progression after HIV Acute/Early Infection: Nothing Compares to CD4⁺ T-cell Count?

    abstract::Progression of HIV infection is variable among individuals, and definition disease progression biomarkers is still needed. Here, we aimed to categorize the predictive potential of several variables using feature selection methods and decision trees. A total of seventy-five treatment-naïve subjects were enrolled during...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10010034

    authors: Turk G,Ghiglione Y,Hormanstorfer M,Laufer N,Coloccini R,Salido J,Trifone C,Ruiz MJ,Falivene J,Holgado MP,Caruso MP,Figueroa MI,Salomón H,Giavedoni LD,Pando MLÁ,Gherardi MM,Rabinovich RD,Pury PA,Sued O

    更新日期:2018-01-13 00:00:00

  • Adenovirus 36 and Obesity: An Overview.

    abstract::There is an epidemic of obesity starting about 1980 in both developed and undeveloped countries definitely associated with multiple etiologies. About 670 million people worldwide are obese. The incidence of obesity has increased in all age groups, including children. Obesity causes numerous diseases and the interactio...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v7072787

    authors: Ponterio E,Gnessi L

    更新日期:2015-07-08 00:00:00

  • Overexpression of MAP2 and NF-H Associated with Dendritic Pathology in the Spinal Cord of Mice Infected with Rabies Virus.

    abstract::Rabies is a viral infection that targets the nervous system, specifically neurons. The clinical manifestations of the disease are dramatic and their outcome fatal; paradoxically, conventional histopathological descriptions reveal only subtle changes in the affected nervous tissue. Some researchers have considered that...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10030112

    authors: Monroy-Gómez J,Santamaría G,Torres-Fernández O

    更新日期:2018-03-06 00:00:00

  • Direct Identification of Enteroviruses in Cerebrospinal Fluid of Patients with Suspected Meningitis by Nested PCR Amplification.

    abstract::Enteroviruses, the most common human viral pathogens worldwide, have been associated with serous meningitis, encephalitis, syndrome of acute flaccid paralysis, myocarditis and the onset of diabetes type 1. In the future, the rapid identification of the etiological agent would allow to adjust the therapy promptly and t...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v8010010

    authors: Krasota A,Loginovskih N,Ivanova O,Lipskaya G

    更新日期:2016-01-06 00:00:00

  • Protoparvovirus Interactions with the Cellular DNA Damage Response.

    abstract::Protoparvoviruses are simple single-stranded DNA viruses that infect many animal species. The protoparvovirus minute virus of mice (MVM) infects murine and transformed human cells provoking a sustained DNA damage response (DDR). This DDR is dependent on signaling by the ATM kinase and leads to a prolonged pre-mitotic ...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v9110323

    authors: Majumder K,Etingov I,Pintel DJ

    更新日期:2017-10-31 00:00:00

  • Vascular endothelial growth factor levels in dobrava/belgrade virus infections.

    abstract::The levels of vascular endothelial growth factor-A (VEGF) were estimated in 102 serum samples from 63 hospitalized Greek patients with hemorrhagic fever with renal syndrome (HFRS) caused by Dobrava/Belgrade virus. Significantly higher VEGF levels were seen in the severe when compared with non-severe cases (mean values...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v5123109

    authors: Tsergouli K,Papa A

    更新日期:2013-12-10 00:00:00

  • Population structure of Lassa Mammarenavirus in West Africa.

    abstract::Lassa mammarenavirus (LASV) is the etiologic agent of Lassa fever. In endemic regions in West Africa, LASV genetic diversity tends to cluster by geographic area. Seven LASV lineages are recognized, but the role of viral genetic determinants on disease presentation in humans is uncertain. We investigated the geographic...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12040437

    authors: Forni D,Sironi M

    更新日期:2020-04-13 00:00:00

  • Eradication of HIV-1 from the macrophage reservoir: an uncertain goal?

    abstract::Human immunodeficiency virus type 1 (HIV-1) establishes latency in resting memory CD4+ T cells and cells of myeloid lineage. In contrast to the T cells, cells of myeloid lineage are resistant to the HIV-1 induced cytopathic effect. Cells of myeloid lineage including macrophages are present in anatomical sanctuaries ma...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v7041578

    authors: Abbas W,Tariq M,Iqbal M,Kumar A,Herbein G

    更新日期:2015-03-31 00:00:00

  • Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic Strategies.

    abstract::Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a curative potential for many hematologic malignancies and blood diseases. However, the success of allo-HSCT is limited by graft-versus-host disease (GVHD), an immunological syndrome that involves inflammation and tissue damage mediated by donor lympho...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v8030085

    authors: Villa NY,Rahman MM,McFadden G,Cogle CR

    更新日期:2016-03-22 00:00:00

  • Molecular signatures of hepatitis C virus (HCV)-induced type II mixed cryoglobulinemia (MCII).

    abstract::The role of hepatitis C virus (HCV) infection in the induction of type II mixed cryoglobulinemia (MCII) and the possible establishment of related lymphoproliferative disorders, such as B-cell non-Hodgkin lymphoma (B-NHL), is well ascertained. However, the molecular pathways involved and the factors predisposing to th...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v4112924

    authors: Sautto G,Mancini N,Clementi M,Burioni R

    更新日期:2012-11-08 00:00:00

  • Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus.

    abstract::Innate immunity is the first line of defense against viral infection, and in turn, viruses have evolved to evade host immune surveillance. As a result, viruses may persist in host and develop chronic infections. Type I interferons (IFN-α/β) are among the most potent antiviral cytokines triggered by viral infections. P...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v4040424

    authors: Sun Y,Han M,Kim C,Calvert JG,Yoo D

    更新日期:2012-04-01 00:00:00

  • High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication.

    abstract::Interferon (IFN) regulatory factor 3 (IRF3) is the key transcription factor for the induction of IFN and antiviral genes. The absence of antiviral genes in IRF3 deficiency leads to susceptibility to a wide range of viral infections. Previously, we uncovered a function for nontranscriptional IRF3 (nt-IRF3), RLR (RIG-I-...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12040442

    authors: Glanz A,Chawla K,Fabry S,Subramanian G,Garcia J,Jay B,Ciricillo J,Chakravarti R,Taylor RT,Chattopadhyay S

    更新日期:2020-04-14 00:00:00

  • Circulation of Toscana Virus in a Sample Population of Corsica, France.

    abstract::Sandfly-borne phleboviruses pathogenic to humans, such as Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV), are endemic in the Mediterranean region. In France, several autochthonous cases of TOSV infection have been described, causing either meningitis or encephalitis. The aim of the present study was to i...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11090817

    authors: Masse S,Ayhan N,Capai L,Bosseur F,de Lamballerie X,Charrel R,Falchi A

    更新日期:2019-09-04 00:00:00

  • Genetic Susceptibility to Human Norovirus Infection: An Update.

    abstract::Noroviruses are the most common etiological agent of acute gastroenteritis worldwide. Despite their high infectivity, a subpopulation of individuals is resistant to infection and disease. This susceptibility is norovirus genotype-dependent and is largely mediated by the presence or absence of human histo-blood group a...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v11030226

    authors: Nordgren J,Svensson L

    更新日期:2019-03-06 00:00:00

  • An Update of the Virion Proteome of Kaposi Sarcoma-Associated Herpesvirus.

    abstract::The virion proteins of Kaposi sarcoma-associated herpesvirus (KSHV) were initially characterized in 2005 in two separate studies that combined the detection of 24 viral proteins and a few cellular components via LC-MS/MS or MALDI-TOF. Despite considerable advances in the sensitivity and specificity of mass spectrometr...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12121382

    authors: Nabiee R,Syed B,Ramirez Castano J,Lalani R,Totonchy JE

    更新日期:2020-12-02 00:00:00

  • Phage Lytic Enzymes.

    abstract::Phage lytic enzymes are enzymes produced by bacterial viruses, either as part of their virion to facilitate bacterial infection through local peptidoglycan degradation, or as soluble proteins to induce massive cell lysis at the end of the lytic replication cycle [...]. ...

    journal_title:Viruses

    pub_type: 社论

    doi:10.3390/v11020113

    authors: Briers Y

    更新日期:2019-01-29 00:00:00

  • Bovine Adenovirus-3 Tropism for Bovine Leukocyte Sub-Populations.

    abstract::A number of characteristics including lack of virulence and the ability to grow to high titers, have made bovine adenovirus-3 (BAdV-3) a vector of choice for further development as a vaccine-delivery vehicle for cattle. Despite the importance of blood leukocytes, including dendritic cells (DC), in the induction of pro...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12121431

    authors: Khosa S,Araya MB,Griebel P,Arsic N,Tikoo SK

    更新日期:2020-12-12 00:00:00

  • Advanced Therapeutics, Vaccinations, and Precision Medicine in the Treatment and Management of Chronic Hepatitis B Viral Infections; Where Are We and Where Are We Going?

    abstract::The management of chronic hepatitis B virus (CHB) infection is an area of massive unmet clinical need worldwide. In spite of the development of powerful nucleoside/nucleotide analogue (NUC) drugs, and the widespread use of immune stimulators such as interferon-alpha (IFNα) or PEGylated interferon-alpha (PEG-IFNα), sub...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v12090998

    authors: Duraisamy GS,Bhosale D,Lipenská I,Huvarova I,Růžek D,Windisch MP,Miller AD

    更新日期:2020-09-07 00:00:00