Importance of Autophagy in Mediating Human Immunodeficiency Virus (HIV) and Morphine-Induced Metabolic Dysfunction and Inflammation in Human Astrocytes.

abstract：:During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of autochthonous hepatitis E in Western countries has increased as well, raising the question of what role these possible animal reservoirs play in human infections. The a...

journal_title：Viruses

authors： Doceul V,Bagdassarian E,Demange A,Pavio N

更新日期：2016-10-03 00:00:00

abstract：:Glycoprotein B (gB) plays an important role in alphaherpesvirus cellular entry and acts in concert with gD and the gH/gL complex. To evaluate whether functional differences exist between gB1 and gB4, the corresponding genes were exchanged between the two viruses. The gB4-containing-EHV-1 (EHV-1_gB4) recombinant virus ...

journal_title：Viruses

authors： Spiesschaert B,Osterrieder N,Azab W

更新日期：2015-02-03 00:00:00

abstract：:The subgroup A through E avian sarcoma and leukosis viruses (ASLV(A) through ASLV(E)) are a group of highly related alpharetroviruses that have evolved their envelope glycoproteins to use different receptors to enable efficient virus entry due to host resistance and/or to expand host range. Previously, we demonstrated...

journal_title：Viruses

authors： Munguia A,Federspiel MJ

更新日期：2019-06-05 00:00:00

abstract：:Rotavirus (RV), a member of the Reoviridae family, causes infection in children and infants, with high morbidity and mortality. To be viable, the virus particle must package a set of eleven RNA segments. In order to understand the packaging mechanism, here, we co-synthesized sets of RNA segments in vitro in different ...

journal_title：Viruses

authors： Fajardo T,Sung PY,Celma CC,Roy P

更新日期：2017-06-29 00:00:00

abstract：:Astroviral infection is considered to be one of the causes of mammalian diarrheal diseases. It has been shown that astrovirus infections cause varying degrees of diarrhea in turkeys and mice. However, the pathogenesis of porcine astrovirus is unknown. In this study, the virulence of a cytopathic porcine astrovirus (PA...

journal_title：Viruses

authors： Fang Q,Wang C,Liu H,Wu Q,Liang S,Cen M,Dong Q,Wei Y,Chen Y,Ouyang K,Wei Z,Huang W

更新日期：2019-12-13 00:00:00

abstract：:Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, the bank vole, is rather continuous. A missing pi...

journal_title：Viruses

authors： Castel G,Couteaudier M,Sauvage F,Pons JB,Murri S,Plyusnina A,Pontier D,Cosson JF,Plyusnin A,Marianneau P,Tordo N

更新日期：2015-10-22 00:00:00

abstract：:Commentary on Pais-Correia, A.M.; Sachse, M.; Guadagnini, S.; Robbiati, V.; Lasserre, R.; Gessain, A.; Gout, O.; Alcover, A.; Thoulouze, M.I. Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses. Nat. Med.2010, 16, 83-89. ...

journal_title：Viruses

authors： Jin J,Sherer N,Mothes W

更新日期：2010-02-01 00:00:00

abstract：:Viral codon usage bias may be the product of a number of synergistic or antagonistic factors, including genomic nucleotide composition, translational selection, genomic architecture, and mutational or repair biases. Most studies of viral codon bias evaluate only the relative importance of genomic base composition and ...

journal_title：Viruses

authors： Cardinale DJ,DeRosa K,Duffy S

更新日期：2013-01-15 00:00:00

abstract：:The world's first natural avian-origin H6N1 influenza A virus infection case in dogs was confirmed in Taiwan in 2014. The H6N1 virus in chickens has been endemic in Taiwan since 1972. Whether the dog H6N1 virus has interspecies transmission potential is the key issue we aim to understand. Following one virus passage i...

journal_title：Viruses

authors： Tsai SK,Shih CH,Chang HW,Teng KH,Hsu WE,Lin HJ,Lin HY,Huang CH,Chen HW,Wang LC

更新日期：2020-06-30 00:00:00

abstract：:Several human monoclonal antibodies (hmAbs) and antibody fragments, including the best characterized in terms of structure-function b12 and Fab X5, exhibit relatively potent and broad HIV-1 neutralizing activity. However, the elicitation of b12 or b12-like antibodies in vivo by vaccine immunogens based on the HIV-1 en...

journal_title：Viruses

authors： Xiao X,Chen W,Feng Y,Dimitrov DS

更新日期：2009-12-01 00:00:00

abstract：:The Bunyaviridae is the largest family of RNA viruses, with over 350 members worldwide. Several of these viruses cause severe diseases in livestock and humans. With an increasing number and frequency of outbreaks, bunyaviruses represent a growing threat to public health and agricultural productivity globally. Yet, the...

journal_title：Viruses

authors： Albornoz A,Hoffmann AB,Lozach PY,Tischler ND

更新日期：2016-05-24 00:00:00

abstract：:Severe fever with thrombocytopenia syndrome (SFTS) is a novel tick-borne infectious disease, therefore, the information on the whole genome of the SFTS virus (SFTSV) is still limited. This study demonstrates a nearly whole genome of the SFTSV identified in Osaka in 2017 and 2018 by next-generation sequencing (NGS). Th...

journal_title：Viruses

authors： Ikemori R,Aoyama I,Sasaki T,Takabayashi H,Morisada K,Kinoshita M,Ikuta K,Yumisashi T,Motomura K

更新日期：2021-01-25 00:00:00

abstract：:Temperate bacteriophages possess a molecular switch, which regulates the lytic and lysogenic growth. The genomes of the temperate telomere phages N15, PY54 and ɸKO2 harbor a primary immunity region (immB) comprising genes for the prophage repressor, the lytic repressor and a putative antiterminator. The roles of these...

journal_title：Viruses

authors： Hammerl JA,Roschanski N,Lurz R,Johne R,Lanka E,Hertwig S

更新日期：2015-06-02 00:00:00

abstract：:Kaposi's sarcoma associated herpesvirus (KSHV), like other human herpes viruses, establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic phases. The latent phase is characterized by the persistence of viral episomes in a highly ordered chromatin structure and with the expression of ...

journal_title：Viruses

authors： Uppal T,Banerjee S,Sun Z,Verma SC,Robertson ES

更新日期：2014-12-11 00:00:00

abstract：:Lentiviruses are infectious agents of a number of animal species, including sheep, goats, horses, monkeys, cows, and cats, in addition to humans. As in the human case, the host immune response fails to control the establishment of chronic persistent infection that finally leads to a specific disease development. Despi...

journal_title：Viruses

authors： de Pablo-Maiso L,Doménech A,Echeverría I,Gómez-Arrebola C,de Andrés D,Rosati S,Gómez-Lucia E,Reina R

更新日期：2018-08-17 00:00:00

abstract：:Baboons are susceptible to natural Ebola virus (EBOV) infection and share 96% genetic homology with humans. Despite these characteristics, baboons have rarely been utilized as experimental models of human EBOV infection to evaluate the efficacy of prophylactics and therapeutics in the United States. This review will s...

journal_title：Viruses

authors： Perry DL,Bollinger L,White GL

更新日期：2012-10-23 00:00:00

abstract：:Human adenovirus type 4 (HAdV-E4), which is intriguingly limited to military populations, causes acute respiratory disease with demonstrated morbidity and mortality implications. This respiratory pathogen contains genome identity with chimpanzee adenoviruses, indicating zoonotic origins. A signature of these "old" HAd...

journal_title：Viruses

authors： Zhang J,Kang J,Dehghan S,Sridhar S,Lau SKP,Ou J,Woo PCY,Zhang Q,Seto D

更新日期：2019-01-31 00:00:00

abstract：:Feline immunodeficiency virus (FIV) is widespread in feline populations and causes an AIDS-like illness in domestic cats. It is highly prevalent in several endangered feline species. In domestic cats FIV infection is a valuable small animal model for HIV infection. In recent years there has been sa significant increas...

journal_title：Viruses

authors： Kenyon JC,Lever AM

更新日期：2011-11-01 00:00:00

abstract：:A wide gap exists between the rapid acceptance of genetically modified (GM) crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the ...

journal_title：Viruses

authors： Lucht JM

更新日期：2015-07-30 00:00:00

abstract：:Via virome sequencing, six viruses were detected from Magnaporthe oryzae strains YC81-2, including one virus in the family Tombusviridae, one virus in the family Narnaviridae and four viruses in the family Botourmiaviridae. Since the RNA-dependent RNA polymerase (RdRp) of one botourmiavirus show the highest identity (...

journal_title：Viruses

authors： Liu Y,Zhang L,Esmael A,Duan J,Bian X,Jia J,Xie J,Cheng J,Fu Y,Jiang D,Lin Y

更新日期：2020-12-03 00:00:00

abstract：:The use of the rabies vaccine for post-exposure prophylaxis started as early as 1885, revealing a safe and efficient tool to prevent human rabies cases. Preventive vaccination is the basis for the control of canine-mediated rabies, which has already been eliminated from extensive parts of the world, including Europe. ...

journal_title：Viruses

authors： Echevarría JE,Banyard AC,McElhinney LM,Fooks AR

更新日期：2019-09-24 00:00:00

abstract：:The begomoviruses (BGVs) are plant pathogens that evolved in the Old World during the Cretaceous and arrived to the New World (NW) in the Cenozoic era. A subgroup of NW BGVs, the "Squash leaf curl virus (SLCV) lineage" (S-Lin), includes viruses with unique characteristics. To get clues on the evolutionary origin of th...

journal_title：Viruses

authors： Torres-Herrera SI,Romero-Osorio A,Moreno-Valenzuela O,Pastor-Palacios G,Cardenas-Conejo Y,Ramírez-Prado JH,Riego-Ruiz L,Minero-García Y,Ambriz-Granados S,Argüello-Astorga GR

更新日期：2019-07-13 00:00:00

abstract：:Zika virus (ZIKV) infection during pregnancy leads to severe congenital Zika syndrome, which includes microcephaly and other neurological malformations. No therapeutic agents have, so far, been approved for the treatment of ZIKV infection in humans; as such, there is a need for a continuous effort to develop effective...

journal_title：Viruses

authors： Gao Y,Tai W,Wang N,Li X,Jiang S,Debnath AK,Du L,Chen S

更新日期：2019-11-02 00:00:00

abstract：:Noroviruses are a leading cause of gastroenteritis worldwide. Although infections in healthy individuals are self-resolving, immunocompromised individuals are at risk for chronic disease and severe complications. Chronic norovirus infections in immunocompromised hosts are often characterized by long-term virus sheddin...

journal_title：Viruses

authors： Davis A,Cortez V,Grodzki M,Dallas R,Ferrolino J,Freiden P,Maron G,Hakim H,Hayden RT,Tang L,Huys A,Kolawole AO,Wobus CE,Jones MK,Karst SM,Schultz-Cherry S

更新日期：2020-06-05 00:00:00

abstract：:Enteroviruses are small RNA viruses that affect millions of people each year by causing an important burden of disease with a broad spectrum of symptoms. In routine diagnostic laboratories, enteroviruses are identified by PCR-based methods, often combined with partial sequencing for genotyping. In this proof-of-princi...

journal_title：Viruses

authors： Grädel C,Terrazos Miani MA,Baumann C,Barbani MT,Neuenschwander S,Leib SL,Suter-Riniker F,Ramette A

更新日期：2020-07-31 00:00:00

abstract：:The Gammacoronavirus infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not replicate in cell culture, making the study of their basic virolo...

journal_title：Viruses

authors： Stevenson-Leggett P,Keep S,Bickerton E

更新日期：2020-09-29 00:00:00

abstract：:Herpesviruses use a vesicle-mediated transfer of intranuclearly assembled nucleocapsids through the nuclear envelope (NE) for final maturation in the cytoplasm. The molecular basis for this novel vesicular nucleo-cytoplasmic transport is beginning to be elucidated in detail. The heterodimeric viral nuclear egress comp...

journal_title：Viruses

authors： Mettenleiter TC

更新日期：2016-09-27 00:00:00

abstract：:Infectious bursal disease (IBD) is an immunosuppressive, highly contagious, and lethal disease of young chickens caused by IBD virus (IBDV). It results in huge economic loss to the poultry industry worldwide. Infection caused by very virulent IBDV (vvIBDV) strains results in high mortality in young chicken flocks. How...

journal_title：Viruses

authors： Yang B,Yan N,Liu A,Li Y,Chen Z,Gao L,Qi X,Gao Y,Liu C,Zhang Y,Cui H,Li K,Pan Q,Wang Y,Wang X

更新日期：2020-02-23 00:00:00

abstract：:West Nile virus (WNV) is a member of the genus Flavivirus in the family Flaviviridae. Flaviviruses replicate in the cytoplasm of infected cells and modify the host cell environment. Although much has been learned about virion structure and virion-endosomal membrane fusion, the cell receptor(s) used have not been defin...

journal_title：Viruses

authors： Brinton MA

更新日期：2013-12-27 00:00:00

abstract：:Alfuy (ALFV) is an attenuated flavivirus related to the Murray Valley encephalitis virus (MVEV). We previously identified markers of attenuation in the envelope (E) protein of the prototype strain (ALFV3929), including the hinge region (E273-277) and lack of glycosylation at E154-156. To further determine the mechanis...

journal_title：Viruses

authors： Westlake D,Bielefeldt-Ohmann H,Prow NAA,Hall RAA

更新日期：2021-01-20 00:00:00