Abstract:
:Via virome sequencing, six viruses were detected from Magnaporthe oryzae strains YC81-2, including one virus in the family Tombusviridae, one virus in the family Narnaviridae and four viruses in the family Botourmiaviridae. Since the RNA-dependent RNA polymerase (RdRp) of one botourmiavirus show the highest identity (79%) with Magnaporthe oryzae ourmia-like virus 1 (MOLV1), the virus that was grouped into the genus Magoulivirus was designated as Magnaporthe oryzae botourmiavirus 2 (MOBV2). The three other novel botourmiaviruses were selected for further study. The complete nucleotide sequences of the three botourmiaviruses were determined. Sequence analysis showed that virus 1, virus 2, and virus 3 were 2598, 2385, and 2326 nts in length, respectively. The variable 3' untranslated region (3'-UTR) and 5'-UTR of each virus could be folded into a stable stem-loop secondary structure. Each virus consisted of a unique ORF encoding a putative RdRp. The putative proteins with a conserved GDD motif of RdRp showed the highest sequence similarity to RdRps of viruses in the family Botourmiaviridae. Phylogenetic analysis demonstrated that these viruses were three distinct novel botourmiaviruses, clustered into the Botourmiaviridae family but not belonging to any known genera of this family. Thus, virus 1, virus 2, and virus 3 were designated as Magnaporthe oryzae botourmiavirus 5, 6, and 7 (MOBV5, MOBV6, and MOBV7), respectively. Our results suggest that four distinct botourmiaviruses, MOBV2, MOBV5, MOBV6, and MOBV7, co-infect a single strain of Magnaporthe oryzae, and MOBV5, MOBV6, and MOBV7 are members of three unclassified genera in the family Botourmiaviridae.
journal_name
Virusesjournal_title
Virusesauthors
Liu Y,Zhang L,Esmael A,Duan J,Bian X,Jia J,Xie J,Cheng J,Fu Y,Jiang D,Lin Ydoi
10.3390/v12121383subject
Has Abstractpub_date
2020-12-03 00:00:00issue
12issn
1999-4915pii
v12121383journal_volume
12pub_type
杂志文章相关文献
Viruses-Basel文献大全abstract::Since the human immunodeficiency virus (HIV) was discovered as the etiological agent of acquired immunodeficiency syndrome (AIDS), it has encouraged much research into antiviral compounds. The reverse transcriptase (RT) of HIV has been a main target for antiviral drugs. However, all drugs developed so far inhibit the ...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v2040900
更新日期:2010-04-01 00:00:00
abstract::Dendritic cells (DCs) are involved in human and simian immunodeficiency virus (HIV and SIV) pathogenesis but also play a critical role in orchestrating innate and adaptive vaccine-specific immune responses. Effective HIV/SIV vaccines require strong antigen-specific CD4 T cell responses, cytotoxic activity of CD8 T cel...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v12010024
更新日期:2019-12-24 00:00:00
abstract::Different developmental stages of Artemia spp. (metanauplii, juveniles and adults) were bath-challenged with two isolates of the Lymphocystis disease virus (LCDV), namely, LCDV SA25 (belonging to the species Lymphocystis disease virus 3) and ATCC VR-342 (an unclassified member of the genus Lymphocystivirus). Viral qua...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11060506
更新日期:2019-06-01 00:00:00
abstract::Bacteriophages represent a valuable source for studying the mechanisms underlying virus-host interactions. A better understanding of the host-specificity of viruses at the molecular level can promote various phage applications, including bacterial diagnostics, antimicrobial therapeutics, and improve methods in molecul...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v7122932
更新日期:2015-11-27 00:00:00
abstract::The mosquito antiviral response has mainly been studied in the context of arthropod-borne virus (arbovirus) infection in female mosquitoes. However, in nature, both female and male mosquitoes are frequently infected with insect-specific viruses (ISVs). ISVs are capable of infecting the reproductive organs of both sexe...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12040468
更新日期:2020-04-21 00:00:00
abstract::Noroviruses are a leading cause of gastroenteritis worldwide. Although infections in healthy individuals are self-resolving, immunocompromised individuals are at risk for chronic disease and severe complications. Chronic norovirus infections in immunocompromised hosts are often characterized by long-term virus sheddin...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12060619
更新日期:2020-06-05 00:00:00
abstract::During the early stages of human papillomavirus (HPV) infections, the innate immune system creates a pro-inflammatory microenvironment by recruiting innate immune cells to eliminate the infected cells, initiating an effective acquired immune response. However, HPV exhibits a wide range of strategies for evading immune...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v5112624
更新日期:2013-10-28 00:00:00
abstract::Cellular receptor-mediated signaling pathways play critical roles during the initial immune response to Human Cytomegalovirus (HCMV) infection. However, the involvement of type-I transmembrane glycoprotein CD147/EMMPRIN (extracellular matrix metalloproteinase inducer) in the antiviral response to HCMV infection is sti...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v9120365
更新日期:2017-12-01 00:00:00
abstract::Persistent circulative transmission of plant viruses involves complex interactions between the transmitted virus and its insect vector. Several studies have shown that insect vector proteins are involved in the passage and the transmission of the virus. Interestingly, proteins expressed by bacterial endosymbionts that...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v5061516
更新日期:2013-06-19 00:00:00
abstract::Arctic marine ecosystems are currently undergoing rapid changes in temperature and light availability. Picophytoplankton, such as Micromonas polaris, are predicted to benefit from such changes. However, little is known about how these environmental changes affect the viruses that exert a strong mortality pressure on t...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10120676
更新日期:2018-11-29 00:00:00
abstract::Human cytomegalovirus (HCMV) encodes a number of viral proteins with homology to cellular G protein-coupled receptors (GPCRs). These viral GPCRs, including US27, US28, UL33, and UL78, have been ascribed numerous functions during infection, including activating diverse cellular pathways, binding to immunomodulatory che...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v6031202
更新日期:2014-03-12 00:00:00
abstract::A field study was undertaken to (i) measure the prevalence of feline leukaemia virus (FeLV) exposure and FeLV infection in a cross-section of healthy Australian pet cats; and (ii) investigate the outcomes following natural FeLV exposure in two Australian rescue facilities. Group 1 (n = 440) consisted of healthy client...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11060503
更新日期:2019-05-31 00:00:00
abstract::Non-human primates (NHP) are the only animal model suitable to evaluate the protection efficacy of HIV-1 vaccines. It is important to understand how and when neutralizing antibodies (nAbs) with specificities similar to those of human broadly neutralizing antibodies (bnAbs) develop in NHPs. To address these questions, ...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12020163
更新日期:2020-01-31 00:00:00
abstract::Porcine epidemic diarrhea (PED) has re-emerged in recent years and has already caused huge economic losses to the porcine industry all over the world. Therefore, it is urgent for us to find out efficient ways to prevent and control this disease. In this study, the antiviral activity of a cationic amphibian antimicrobi...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10090507
更新日期:2018-09-18 00:00:00
abstract::African swine fever is a highly lethal hemorrhagic fever of Suidae, threatening pig production globally. Suidae can be infected by different ways like ingestion of contaminated feed, direct contact with infected animals or fomites, and biting by infected soft tick bites. As already described, European soft ticks (Orni...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12030300
更新日期:2020-03-11 00:00:00
abstract::The Vibrio cholerae biotype "El Tor" is responsible for all of the current epidemic and endemic cholera outbreaks worldwide. These outbreaks are clonal, and it is hypothesized that they originate from the coastal areas near the Bay of Bengal, where the lytic bacteriophage ICP1 (International Centre for Diarrhoeal Dise...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10060299
更新日期:2018-06-01 00:00:00
abstract::Infectious retrovirus particles contain two copies of unspliced viral RNA that serve as the viral genome. Unspliced retroviral RNA is transcribed in the nucleus by the host RNA polymerase II and has three potential fates: (1) it can be spliced into subgenomic messenger RNAs (mRNAs) for the translation of viral protein...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v8090257
更新日期:2016-09-20 00:00:00
abstract::Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses with global impact on the health of domestic cats. The two viruses differ in their potential to cause disease. FeLV is more pathogenic, and was long considered to be responsible for more clinical syndromes than any other agent in cat...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v4112684
更新日期:2012-10-31 00:00:00
abstract::Around 257 million people are living with hepatitis B virus (HBV) chronic infection and 71 million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead to liver complications such as cirrhosis and hepatocellular carcinoma (HCC). To take care of these chronically infected patients, one s...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v12121440
更新日期:2020-12-14 00:00:00
abstract::In the last 20 years, molecular ecology approaches have proven to be extremely useful to identify and assess factors associated with viral emerging diseases, particularly in economically and socially important tropical crops such as maize (maize streak disease) and cassava (cassava mosaic disease). Molecular ecology a...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v4123665
更新日期:2012-12-12 00:00:00
abstract::Hepatitis C is a major global health burden with an estimated 160 million infected individuals worldwide. This long-term disease evolves slowly, often leading to chronicity and potentially to liver failure. There is no anti-HCV vaccine, and, until recently, the only treatment available, based on pegylated interferon a...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v4102197
更新日期:2012-10-17 00:00:00
abstract::Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular evolution of peptide-displayed libraries in mammalian model systems, using in vivo phage di...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11110988
更新日期:2019-10-26 00:00:00
abstract::Using different prion strains, such as the variant Creutzfeldt-Jakob disease agent and the atypical bovine spongiform encephalopathy agents, and using transgenic mice expressing human or bovine prion protein, we assessed the reliability of protein misfolding cyclic amplification (PMCA) to model interspecies and geneti...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v6103766
更新日期:2014-10-02 00:00:00
abstract::The recent emergence and rapid geographic expansion of Zika virus (ZIKV) poses a significant challenge for public health. Although historically causing only mild febrile illness, recent ZIKV outbreaks have been associated with more severe neurological complications, such as Guillain-Barré syndrome and fetal microcepha...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10120728
更新日期:2018-12-19 00:00:00
abstract::A myriad of factors favor the emergence and re-emergence of arthropod-borne viruses (arboviruses), including migration, climate change, intensified livestock production, an increasing volume of international trade and transportation, and changes to ecosystems (e.g., deforestation and loss of biodiversity). Consequentl...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v3060629
更新日期:2011-06-01 00:00:00
abstract::Heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar) was first diagnosed in Norway in 1999. The disease is caused by Piscine orthoreovirus-1 (PRV-1). The virus is prevalent in farmed Atlantic salmon, but not always associated with disease. Phylogeny and sequence analyses of 31 PRV-1 ge...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11050465
更新日期:2019-05-22 00:00:00
abstract::Nipah virus (NiV) is an emerging zoonotic virus that is transmitted by bats to humans and to pigs, causing severe respiratory disease and often fatal encephalitis. Antibodies directed against the NiV-glycoprotein (G) protein are known to play a major role in clearing NiV infection and in providing vaccine-induced prot...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12010026
更新日期:2019-12-24 00:00:00
abstract::Peste des petits ruminants virus (PPRV) causes a contagious disease of high morbidity and mortality in global sheep and goat populations. To better control this disease and inform eradication strategies, an improved understanding of how PPRV transmission risk varies by age is needed. Our study used a piece-wise cataly...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12020186
更新日期:2020-02-07 00:00:00
abstract::Human T-cell leukemia virus type 1 (HTLV-1) is an important cancer-causing human retrovirus that has infected approximately 15 million individuals worldwide. Many aspects of HTLV-1 replication, including virus particle structure and assembly, are poorly understood. Group-specific antigen (Gag) proteins labeled at the ...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v9070191
更新日期:2017-07-19 00:00:00
abstract::Hepatitis delta virus (HDV) is currently only found in humans and is a satellite virus that depends on hepatitis B virus (HBV) envelope proteins for assembly, release, and entry. Using meta-transcriptomics, we identified the genome of a novel HDV-like agent in ducks. Sequence analysis revealed secondary structures tha...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10120720
更新日期:2018-12-17 00:00:00