Abstract：
:Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses with global impact on the health of domestic cats. The two viruses differ in their potential to cause disease. FeLV is more pathogenic, and was long considered to be responsible for more clinical syndromes than any other agent in cats. FeLV can cause tumors (mainly lymphoma), bone marrow suppression syndromes (mainly anemia), and lead to secondary infectious diseases caused by suppressive effects of the virus on bone marrow and the immune system. Today, FeLV is less commonly diagnosed than in the previous 20 years; prevalence has been decreasing in most countries. However, FeLV importance may be underestimated as it has been shown that regressively infected cats (that are negative in routinely used FeLV tests) also can develop clinical signs. FIV can cause an acquired immunodeficiency syndrome that increases the risk of opportunistic infections, neurological diseases, and tumors. In most naturally infected cats, however, FIV itself does not cause severe clinical signs, and FIV-infected cats may live many years without any health problems. This article provides a review of clinical syndromes in progressively and regressively FeLV-infected cats as well as in FIV-infected cats.
journal_name
Virusesjournal_title
Virusesauthors
Hartmann Kdoi
10.3390/v4112684subject
Has Abstractpub_date
2012-10-31 00:00:00pages
2684-710issue
11issn
1999-4915pii
v4112684journal_volume
4pub_type
杂志文章,评审相关文献
Viruses-Basel文献大全abstract：:Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal. The host range and tissue tropism are largely determined by the coronaviral spike protein, which initiates cellular infection b...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v12091023
更新日期：2020-09-13 00:00:00
abstract：:RNA secondary structures play diverse roles in positive-sense (+) RNA virus infections, but those located with the replication protein coding sequence can be difficult to investigate. Structures that regulate the translation of replication proteins pose particular challenges, as their potential involvement in post-tra...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12030350
更新日期：2020-03-22 00:00:00
abstract：:Autophagy is an essential vacuolar process of the cell, leading to lysosomal degradation and recycling of proteins and organelles, which is extremely important in maintaining homeostasis. Multiple roles have been now associated with autophagy, in particular a pro-survival role in nutrient starvation or in stressful en...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9120372
更新日期：2017-12-04 00:00:00
abstract：:Retroviruses integrate a reverse transcribed double stranded DNA copy of their viral genome into the chromosomal DNA of cells they infect. Occasionally, exogenous retroviruses infect germ cells and when this happens a profound shift in the virus host dynamic occurs. Retroviruses maintained as hereditable viral genetic...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v3060901
更新日期：2011-06-01 00:00:00
abstract：:The impact of topical applications of deltamethrin and ivermectin to cattle on Culicoides spp. landing and blood-feeding was studied in this work using sticky traps mounted on Friesian heifers' backs. There was no effect of the insecticides on total numbers of Culicoides trapped or the proportion engorged. Deltamethri...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11080731
更新日期：2019-08-08 00:00:00
abstract：:The capsid domain (CA) of the lentiviral Gag polyproteins has two distinct roles during virion morphogenesis. As a domain of Gag, it mediates the Gag-Gag interactions that drive immature particle assembly, whereas as a mature protein, it self-assembles into the conical core of the mature virion. Lentiviral CA proteins...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11090816
更新日期：2019-09-04 00:00:00
abstract：:Cytoskeleton defines the shape and structural organization of the cell. Its elements participate in cell motility, intracellular transport and chromosome movement during mitosis. Papillomaviruses (PV) are strictly epitheliotropic and induce self-limiting benign tumors of skin and mucosa, which may progress to malignan...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v3030260
更新日期：2011-03-01 00:00:00
abstract：:Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance arises from mutation fixation in the viral genome during antiretroviral therapy. Primary mutations directly confer antiviral drug resistance, while secondary mutations arise that do not confer drug resistance. The A62V amino acid substitution in ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10070376
更新日期：2018-07-19 00:00:00
abstract：:Arctic marine ecosystems are currently undergoing rapid changes in temperature and light availability. Picophytoplankton, such as Micromonas polaris, are predicted to benefit from such changes. However, little is known about how these environmental changes affect the viruses that exert a strong mortality pressure on t...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10120676
更新日期：2018-11-29 00:00:00
abstract：:Thermobifida fusca is of biotechnological interest due to its ability to produce an array of plant cell wall hydrolytic enzymes. Nonetheless, only one T. fusca bacteriophage with genome information has been reported to date. This study was aimed at discovering more relevant bacteriophages to expand the existing knowle...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11111042
更新日期：2019-11-08 00:00:00
abstract：:Cotton leaf curl disease (CLCuD) is one of the most economically important diseases and is a constraint to cotton production in major producers, Pakistan and India. CLCuD is caused by monopartite plant viruses belonging to the family Geminiviridae (genus Begomovirus), in association with an essential, disease-specific...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9100280
更新日期：2017-09-29 00:00:00
abstract：:In response to viral infection, host cells activate various antiviral responses to inhibit virus replication. While feline herpesvirus 1 (FHV-1) manipulates the host early innate immune response in many different ways, the host could activate the antiviral response to counteract it through some unknown mechanisms. Mic...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12010002
更新日期：2019-12-18 00:00:00
abstract：:Preclinical infection model systems are extremely valuable tools to aid in our understanding of Human Papillomavirus (HPV) biology, disease progression, prevention, and treatments. In this context, rodent papillomaviruses and their respective infection models are useful tools but remain underutilized resources in the ...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9120362
更新日期：2017-11-27 00:00:00
abstract：:The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system is widely explored for sequence-specific attack on HIV-1 proviral DNA. We recently identified dual-guide RNA (dual-gRNA) combinations that can block HIV-1 replication permanently in infected cell cultures and prevent viral escape. Altho...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11030255
更新日期：2019-03-13 00:00:00
abstract：:Bombyx mori nuclear polyhedrosis virus (BmNPV) is an important pathogen of silkworms. Despite extensive studies in recent decades, the interaction between BmNPV and host cells is still not clearly understood. Autophagy is an intrinsic innate immune mechanism and it controls infection autonomously in virus-infected cel...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10010014
更新日期：2017-12-30 00:00:00
abstract：:: Rabies virus (RABV) is the only lyssavirus known to be present within the Caribbean. The island of Trinidad, is richly diverse in chiropteran fauna and endemic for bat-transmitted rabies with low RABV isolation rates observed in this population. We aimed to determine the seroprevalence of rabies virus neutralizing a...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12020178
更新日期：2020-02-05 00:00:00
abstract：:We describe herein, limitations on research at biosafety level 4 (BSL-4) containment laboratories, with regard to biosecurity regulations, safety considerations, research space limitations, and physical constraints in executing experimental procedures. These limitations can severely impact the number of collaborations...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v4123932
更新日期：2012-12-01 00:00:00
abstract：:Kaposi's sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes. KSHV infection is typically asymptomatic, but immunosuppression can predispose KSHV-infected individuals to primary effusion lymphoma (PEL); a malignancy ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12010012
更新日期：2019-12-20 00:00:00
abstract：:The honey bee queen is the central hub of a colony to produce eggs and release pheromones to maintain social cohesion. Among many environmental stresses, viruses are a major concern to compromise the queen's health and reproductive vigor. Viruses have evolved numerous strategies to infect queens either via vertical tr...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v12030322
更新日期：2020-03-17 00:00:00
abstract：:The feline immunodeficiency virus (FIV) vaccine called Fel-O-Vax® FIV is the first commercial FIV vaccine released worldwide for the use in domestic cats against global FIV subtypes (A⁻E). This vaccine consists of inactivated dual-subtype (A plus D) FIV-infected cells, whereas its prototype vaccine consists of inactiv...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v10050277
更新日期：2018-05-22 00:00:00
abstract：:Astroviruses (AstVs) cause disease in a wide variety of species. Porcine AstVs are highly genetically diverse and conventionally assigned to five genetic lineages (PoAstV1-5). Due to the increasing evidence that porcine astrovirus type 3 (PoAstV3) is a cause of encephalomyelitis in swine and to elucidate important eco...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12090992
更新日期：2020-09-07 00:00:00
abstract：:One of the major obstacles that must be overcome in the design of effective lentiviral vaccines is the ability of lentiviruses to evolve in order to escape from neutralizing antibodies. The primary target for neutralizing antibodies is the highly variable viral envelope glycoprotein (Env), a glycoprotein that is essen...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v3101870
更新日期：2011-10-01 00:00:00
abstract：:Developments of genome amplification techniques have rapidly expanded the family of human polyomaviruses (PyV). Following infection early in life, PyV persist in their hosts and are generally of no clinical consequence. High-level replication of PyV can occur in patients under immunosuppressive or immunomodulatory the...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v8100292
更新日期：2016-10-22 00:00:00
abstract：:Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hooved animals that poses a constant burden on farmers in endemic regions and threatens the livestock industries in disease-free countries. Despite the increased number of publicly available whole genome sequences, FMDV data are biased by...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10040192
更新日期：2018-04-13 00:00:00
abstract：:Cyclophilins are peptidyl-prolyl cis/trans isomerases important in the proper folding of certain proteins. Mounting evidence supports varied roles of cyclophilins, either positive or negative, in the life cycles of diverse viruses, but the nature and mechanisms of these roles are yet to be defined. The potential for c...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v5071684
更新日期：2013-07-11 00:00:00
abstract：:Diagnostic electron microscopy for infectious diseases has the advantage that "everything" in the specimen can be observed, without a priori knowledge of the likely identity of the microorganisms present in the sample. The classical specimen preparation method used employs a droplet of sample, which allows particles t...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v6093458
更新日期：2014-09-19 00:00:00
abstract：:Human immunodeficiency virus (HIV) is a causative agent of acquired immune deficiency syndrome (AIDS). Highly active antiretroviral therapy (HAART) can slow down the replication of HIV-1, leading to an improvement in the survival of HIV-1-infected patients. However, drug toxicities and poor drug administration has led...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9100281
更新日期：2017-09-29 00:00:00
abstract：:Foot-and-mouth disease virus (FMDV) causes a highly contagious disease with catastrophic economic impact for affected countries. BHK21 suspension cells are preferred for the industrial production of FMDV vaccine antigen, but not all virus strains can be successfully propagated in these cells. Serotype Asia-1 is often ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v9080231
更新日期：2017-08-18 00:00:00
abstract：:On average, there are 3-5 million severe cases of influenza virus infections globally each year. Seasonal influenza vaccines provide limited protection against divergent influenza strains. Therefore, the development of a universal influenza vaccine is a top priority for the NIH. Here, we report a comprehensive summary...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v12101186
更新日期：2020-10-20 00:00:00
abstract：:Eukaryotic translation is a complex process composed of three main steps: initiation, elongation, and termination. During infections by RNA- and DNA-viruses, the eukaryotic translation machinery is used to assure optimal viral protein synthesis. Human immunodeficiency virus type I (HIV-1) uses several non-canonical pa...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v7010199
更新日期：2015-01-19 00:00:00
