In Vitro Inhibition of Zika Virus Replication with Poly(Sodium 4-Styrenesulfonate).

abstract：:An equine parvovirus-hepatitis (EqPV-H) has been recently identified in association with equine serum hepatitis, also known as Theiler's disease. This disease was first described by Arnold Theiler in 1918 and is often observed after applications with blood products in equines. So far, the virus has only been described...

journal_title：Viruses

authors： Meister TL,Tegtmeyer B,Postel A,Cavalleri JV,Todt D,Stang A,Steinmann E

更新日期：2019-05-21 00:00:00

abstract：:Mechanistic models are critical for our understanding of both within-host dynamics (i.e., pathogen replication and immune system processes) and among-host dynamics (i.e., transmission). Within-host models, however, are not often fit to experimental data, which can serve as a robust method of hypothesis testing and hyp...

journal_title：Viruses

authors： Mihaljevic JR,Greer AL,Brunner JL

更新日期：2019-04-27 00:00:00

abstract：:The assembly of a hexameric lattice of retroviral immature particles requires the involvement of cell factors such as proteins and small molecules. A small, negatively charged polyanionic molecule, myo-inositol hexaphosphate (IP6), was identified to stimulate the assembly of immature particles of HIV-1 and other lenti...

journal_title：Viruses

authors： Dostálková A,Vokatá B,Kaufman F,Ulbrich P,Ruml T,Rumlová M

更新日期：2021-01-18 00:00:00

abstract：:Hantaviruses, members of the order Bunyavirales, family Hantaviridae, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year. The spectrum of disease associated with hantavirus infection include hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrom...

journal_title：Viruses

authors： Brocato RL,Hooper JW

更新日期：2019-07-04 00:00:00

abstract：:Human parechovirus (HPeV), particularly type 3 (HPeV3), is an important cause of sepsis-/meningitis-like illness in young infants. Laboratory records identified a total of ten HPeV-positive cases in Southeastern Australia between January and July 2019. The HPeV present in these cases were typed by Sanger sequencing of...

journal_title：Viruses

authors： Chamings A,Liew KC,Reid E,Athan E,Raditsis A,Vuillermin P,Yoga Y,Caly L,Druce J,Alexandersen S

更新日期：2019-10-03 00:00:00

abstract：:We previously hypothesized that increased capillary permeability observed in both hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS) may be caused by hantavirus-specific cytotoxic T cells attacking endothelial cells presenting viral antigens on their surface based on clinical o...

journal_title：Viruses

authors： Terajima M,Ennis FA

更新日期：2011-07-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is currently only found in humans and is a satellite virus that depends on hepatitis B virus (HBV) envelope proteins for assembly, release, and entry. Using meta-transcriptomics, we identified the genome of a novel HDV-like agent in ducks. Sequence analysis revealed secondary structures tha...

journal_title：Viruses

authors： Wille M,Netter HJ,Littlejohn M,Yuen L,Shi M,Eden JS,Klaassen M,Holmes EC,Hurt AC

更新日期：2018-12-17 00:00:00

abstract：:Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a curative potential for many hematologic malignancies and blood diseases. However, the success of allo-HSCT is limited by graft-versus-host disease (GVHD), an immunological syndrome that involves inflammation and tissue damage mediated by donor lympho...

journal_title：Viruses

authors： Villa NY,Rahman MM,McFadden G,Cogle CR

更新日期：2016-03-22 00:00:00

abstract：:Alfuy (ALFV) is an attenuated flavivirus related to the Murray Valley encephalitis virus (MVEV). We previously identified markers of attenuation in the envelope (E) protein of the prototype strain (ALFV3929), including the hinge region (E273-277) and lack of glycosylation at E154-156. To further determine the mechanis...

journal_title：Viruses

authors： Westlake D,Bielefeldt-Ohmann H,Prow NAA,Hall RAA

更新日期：2021-01-20 00:00:00

abstract：:The RNA3 species of the beet necrotic yellow vein virus (BNYVV), a multipartite positive-stranded RNA phytovirus, contains the 'core' nucleotide sequence required for its systemic movement in Beta macrocarpa. Within this 'core' sequence resides a conserved "coremin" motif of 20 nucleotides that is absolutely essential...

journal_title：Viruses

authors： Flobinus A,Chevigny N,Charley PA,Seissler T,Klein E,Bleykasten-Grosshans C,Ratti C,Bouzoubaa S,Wilusz J,Gilmer D

更新日期：2018-03-19 00:00:00

abstract：:HIV-1 Gag polyprotein orchestrates the assembly of viral particles. Its C-terminus consists of the nucleocapsid (NC) domain that interacts with nucleic acids, and p1 and p6, two unstructured regions, p6 containing the motifs to bind ALIX, the cellular ESCRT factor TSG101 and the viral protein Vpr. The processing of Ga...

journal_title：Viruses

authors： Mouhand A,Pasi M,Catala M,Zargarian L,Belfetmi A,Barraud P,Mauffret O,Tisné C

更新日期：2020-09-29 00:00:00

abstract：:Small Ruminant Lentiviruses (SRLVs) are widespread in many countries and cause economically relevant, slow, and persistent diseases in sheep and goats. Monitoring the genetic diversity of SRLVs is useful to improve the diagnostic tools used in the eradication programs. In this study, SRLVs detected in Spanish Assaf sh...

journal_title：Viruses

authors： Gayo E,Cuteri V,Polledo L,Rossi G,García Marín JF,Preziuso S

更新日期：2018-06-09 00:00:00

abstract：:Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral (PRRSV) disease in pigs characterized by poor reproductive health, increased mortality, and reductions in growth rates. PRRSV is known to implement immuno-antagonistic mechanisms to evade detection and mute host responses to infection. To bette...

journal_title：Viruses

authors： Hicks JA,Yoo D,Liu HC

更新日期：2020-11-12 00:00:00

abstract：:Beyond acute infections, group B coxsackieviruses (CVB) are also reported to play a role in the development of chronic diseases, like type 1 diabetes. The viral pathogenesis mainly relies on the interplay between the viruses and innate immune response in genetically-susceptible individuals. We investigated the interac...

journal_title：Viruses

authors： Alidjinou EK,Sané F,Trauet J,Copin MC,Hober D

更新日期：2015-11-24 00:00:00

abstract：:Heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar) was first diagnosed in Norway in 1999. The disease is caused by Piscine orthoreovirus-1 (PRV-1). The virus is prevalent in farmed Atlantic salmon, but not always associated with disease. Phylogeny and sequence analyses of 31 PRV-1 ge...

journal_title：Viruses

authors： Dhamotharan K,Tengs T,Wessel Ø,Braaen S,Nyman IB,Hansen EF,Christiansen DH,Dahle MK,Rimstad E,Markussen T

更新日期：2019-05-22 00:00:00

abstract：:The orthopoxviruses (OPV) comprise several emerging viruses with great importance to human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of bovine vaccinia (BV) in South America. Historically, VACV is the most comprehensively studied virus, however, its origin and natural hosts remai...

journal_title：Viruses

authors： Oliveira JS,Figueiredo PO,Costa GB,Assis FL,Drumond BP,da Fonseca FG,Nogueira ML,Kroon EG,Trindade GS

更新日期：2017-11-15 00:00:00

abstract：:Although the concept of high-level containment care (HLCC or 'biocontainment'), dates back to 1969, the 2014-2016 outbreak of Ebola virus disease (EVD) brought with it a renewed emphasis on the use of specialized HLCC units in the care of patients with EVD. Employment of these units in the United States and Western Eu...

journal_title：Viruses

authors： Cieslak TJ,Herstein JJ,Kortepeter MG,Hewlett AL

更新日期：2019-08-22 00:00:00

abstract：:Negative strand RNA viruses (NSVs) include many important human pathogens, such as influenza virus, Ebola virus, and rabies virus. One of the unique characteristics that NSVs share is the assembly of the nucleocapsid and its role in viral RNA synthesis. In NSVs, the single strand RNA genome is encapsidated in the line...

journal_title：Viruses

authors： Luo M,Terrell JR,Mcmanus SA

更新日期：2020-07-30 00:00:00

abstract：:Since deer were introduced into Australia in the mid-1800s, their wild populations have increased in size and distribution, posing a potential risk to the livestock industry, through their role in pathogen transmission cycles. In comparison to livestock, there are limited data on viral infections in all wildlife, incl...

journal_title：Viruses

authors： Huaman JL,Pacioni C,Forsyth DM,Pople A,Hampton JO,Carvalho TG,Helbig KJ

更新日期：2020-07-13 00:00:00

abstract：:H1N1 swine influenza viruses (SIV) are prevalent in pigs globally, and occasionally emerge in humans, which raises concern about their pandemic threats. To stimulate hemagglutination (HA) of A/Swine/Guangdong/LM/2004 (H1N1) (SW/GD/04) antibody response, eukaryotic expression plasmid pCI-neo-HA was constructed and used...

journal_title：Viruses

authors： Liu Y,Li H,Xue Y,Zhao S,Li C,Qu L,Zhang Y,Liu M

更新日期：2017-08-08 00:00:00

abstract：:Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by photosensitization has been applied with success since the first decades of the last century. Due to the fact that mammalian viruses are known to p...

journal_title：Viruses

authors： Costa L,Faustino MA,Neves MG,Cunha A,Almeida A

更新日期：2012-07-01 00:00:00

abstract：:Although there have been many epidemiological reports of the inter-country transmission of measles, systematic analysis of the global transmission dynamics of the measles virus (MV) is limited. In this study, we applied phylogeographic analysis to characterize the global transmission dynamics of the MV using large-sca...

journal_title：Viruses

authors： Furuse Y,Oshitani H

更新日期：2017-04-16 00:00:00

abstract：:Salmonid alphavirus (SAV) is the cause of pancreas disease and sleeping disease in farmed salmonid fish in Europe. The spread of these diseases has been difficult to control with biosecurity and current vaccination strategies, and increased understanding of the viral pathogenesis could be beneficial for the developmen...

journal_title：Viruses

authors： Aksnes I,Markussen T,Braaen S,Rimstad E

更新日期：2020-09-24 00:00:00

abstract：:We determined the earliest full-length HIV-1 gag gene sequences in 110 patients with HIV-1, including 20 hemophiliacs (HPs) and 90 local controls (LCs). The gag gene from stored sera was amplified using RT-PCR, and was subjected to direct sequencing. Phylogenetic analysis indicated that 94 and 16 sequences belonged to...

journal_title：Viruses

authors： Cho YK,Kim JE,Foley BT

更新日期：2019-06-11 00:00:00

abstract：:Virus transmission is essential for spreading viral infections and is a highly coordinated process which occurs by cell-free transmission or cell-cell contact. The transmission of Bovine Foamy Virus (BFV) is highly cell-associated, with undetectable cell-free transmission. However, BFV particle budding can be induced ...

journal_title：Viruses

authors： Bao Q,Hipp M,Hugo A,Lei J,Liu Y,Kehl T,Hechler T,Löchelt M

更新日期：2015-11-11 00:00:00

abstract：:Research on human enteroviruses has resulted in the identification of more than 100 enterovirus types, which use more than 10 protein receptors and/or attachment factors required in cell binding and initiation of the replication cycle. Many of these "viral" receptors are overexpressed in cancer cells. Receptor binding...

journal_title：Viruses

authors： Ylä-Pelto J,Tripathi L,Susi P

更新日期：2016-02-23 00:00:00

abstract：:Effects of elevated pCO₂ on Emiliania huxleyi genetic diversity and the viruses that infect E. huxleyi (EhVs) have been investigated in large volume enclosures in a Norwegian fjord. Triplicate enclosures were bubbled with air enriched with CO₂ to 760 ppmv whilst the other three enclosures were bubbled with air at ambi...

journal_title：Viruses

authors： Highfield A,Joint I,Gilbert JA,Crawfurd KJ,Schroeder DC

更新日期：2017-03-08 00:00:00

abstract：:Enteroviruses, the most common human viral pathogens worldwide, have been associated with serous meningitis, encephalitis, syndrome of acute flaccid paralysis, myocarditis and the onset of diabetes type 1. In the future, the rapid identification of the etiological agent would allow to adjust the therapy promptly and t...

journal_title：Viruses

authors： Krasota A,Loginovskih N,Ivanova O,Lipskaya G

更新日期：2016-01-06 00:00:00

abstract：:Sea star wasting disease (SSWD) is a condition that has affected asteroids for over 120 years, yet mechanistic understanding of this wasting etiology remains elusive. We investigated temporal virome variation in two Pisaster ochraceus specimens that wasted in the absence of external stimuli and two specimens that did ...

journal_title：Viruses

authors： Hewson I,Aquino CA,DeRito CM

更新日期：2020-11-20 00:00:00

abstract：:Seoul virus (SEOV) is a zoonotic orthohantavirus carried by black and brown rats, and can cause hemorrhagic fever with renal syndrome in humans. Human cases of SEOV virus infection have most recently been reported in the USA, United Kingdom, France and the Netherlands and were primarily associated with contact with pe...

journal_title：Viruses

authors： Maas M,van Heteren M,de Vries A,Kuiken T,Hoornweg T,Veldhuis Kroeze E,Rockx B

更新日期：2019-06-07 00:00:00