An Emerging Human Parechovirus Type 5 Causing Sepsis-Like Illness in Infants in Australia.

abstract：:HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we found that exosomes, a type of extracellular vesicle (EV), from uninfected cells activate the transcription of HIV-1 ...

journal_title：Viruses

authors： Barclay RA,Mensah GA,Cowen M,DeMarino C,Kim Y,Pinto DO,Erickson J,Kashanchi F

更新日期：2020-06-19 00:00:00

abstract：:One hundred Prunus trees, including almond (P. dulcis), apricot (P. armeniaca), nectarine (P. persica var. nucipersica), peach (P. persica), plum (P. domestica), purple leaf plum (P. cerasifera) and sweet cherry (P. avium), were selected from growing regions Australia-wide and tested for the presence of 34 viruses and...

journal_title：Viruses

authors： Kinoti WM,Nancarrow N,Dann A,Rodoni BC,Constable FE

更新日期：2020-02-23 00:00:00

abstract：:: African swine fever is a devastating hemorrhagic infectious disease, which affects domestic and wild swines (Susscrofa) of all breeds and ages, with a high lethality of up to 90-100% in naïve animals. The causative agent, African swine fever virus (ASFV), is a large and complex double-stranded DNA arbovirus which is...

journal_title：Viruses

authors： Montaner-Tarbes S,Pujol M,Jabbar T,Hawes P,Chapman D,Portillo HD,Fraile L,Sánchez-Cordón PJ,Dixon L,Montoya M

更新日期：2019-09-20 00:00:00

abstract：:Hepatitis B virus (HBV) persistence is at the basis of HBV reactivation as a consequence of chemotherapy and immunosuppressive treatments. The identification of early viral replication indicators and markers of effective HBV immunological control would be useful in monitoring patients who are at risk of potential vira...

journal_title：Viruses

authors： Svicher V,Salpini R,Malagnino V,Piermatteo L,Alkhatib M,Cerva C,Sarmati L

更新日期：2019-08-25 00:00:00

abstract：:Bovine rotavirus A (RVA), a major causative pathogen of diarrhea in dairy and Japanese beef calves, has led to severe economic losses in numerous countries. A dual genotyping system based on genomic segments encoding VP7 (G genotype) and VP4 (P genotype), comprising the outer layer of the virion, has been used to unde...

journal_title：Viruses

authors： Odagiri K,Yoshizawa N,Sakihara H,Umeda K,Rahman S,Nguyen SV,Suzuki T

更新日期：2020-12-03 00:00:00

abstract：:The development of oncolytic viruses has led to an emerging new class of cancer therapeutics. Although the safety profile has been encouraging, the transition of oncolytic viruses to the clinical setting has been a slow process due to modifications. Therefore, a new generation of more potent oncolytic viruses needs to...

journal_title：Viruses

authors： Yuan M,Webb E,Lemoine NR,Wang Y

更新日期：2016-03-07 00:00:00

abstract：:Extracellular vesicles (EVs) play an important role in intercellular communication. They are naturally released from cells into the extracellular environment. Based on their biogenesis, release pathways, size, content, and function, EVs are classified into exosomes, microvesicles (MVs), and apoptotic bodies (ApoBDs). ...

journal_title：Viruses

authors： Alqatawni A,Sharma AL,Attilus B,Tyagi M,Daniel R

更新日期：2020-05-27 00:00:00

abstract：:Cytoskeleton defines the shape and structural organization of the cell. Its elements participate in cell motility, intracellular transport and chromosome movement during mitosis. Papillomaviruses (PV) are strictly epitheliotropic and induce self-limiting benign tumors of skin and mucosa, which may progress to malignan...

journal_title：Viruses

authors： Bienkowska-Haba M,Sapp M

更新日期：2011-03-01 00:00:00

abstract：:Countries rely on good diagnostic tests and appropriate testing schemes to fight against economically important small ruminant lentivirus (SRLV) infections. We undertook an extensive comparative analysis of seven commercially available serological tests and one in-house real-time PCR (qPCR) detecting genotype A and B ...

journal_title：Viruses

authors： Michiels R,Van Mael E,Quinet C,Adjadj NR,Cay AB,De Regge N

更新日期：2018-12-08 00:00:00

abstract：:Enteroviruses, the most common human viral pathogens worldwide, have been associated with serous meningitis, encephalitis, syndrome of acute flaccid paralysis, myocarditis and the onset of diabetes type 1. In the future, the rapid identification of the etiological agent would allow to adjust the therapy promptly and t...

journal_title：Viruses

authors： Krasota A,Loginovskih N,Ivanova O,Lipskaya G

更新日期：2016-01-06 00:00:00

abstract：:Aplastic anemia is a rare blood disease characterized by the destruction of the hematopoietic stem cells (HSC) in the bone marrow that, in the majority of cases, is caused by an autoimmune reaction. Patients with aplastic anemia are treated with immunosuppressive drugs and some of them, especially younger individuals ...

journal_title：Viruses

authors： Inoue H,Rai S,Tanaka H,Espinoza JL,Komori-Inoue M,Kakutani H,Minamoto S,Kumode T,Nakayama S,Taniguchi Y,Morita Y,Okuda T,Tatsumi Y,Ashida T,Matsumura I

更新日期：2020-04-08 00:00:00

abstract：:Foodborne illnesses remain a major cause of hospitalization and death worldwide despite many advances in food sanitation techniques and pathogen surveillance. Traditional antimicrobial methods, such as pasteurization, high pressure processing, irradiation, and chemical disinfectants are capable of reducing microbial p...

journal_title：Viruses

authors： Moye ZD,Woolston J,Sulakvelidze A

更新日期：2018-04-19 00:00:00

abstract：:Two sister orders of the brown macroalgae (class Phaeophyceae), the morphologically complex Laminariales (commonly referred to as kelp) and the morphologically simple Ectocarpales are natural hosts for the dsDNA phaeoviruses (family Phycodnaviridae) that persist as proviruses in the genomes of their hosts. We have pre...

journal_title：Viruses

authors： McKeown DA,Schroeder JL,Stevens K,Peters AF,Sáez CA,Park J,Rothman MD,Bolton JJ,Brown MT,Schroeder DC

更新日期：2018-08-05 00:00:00

abstract：:Negative strand RNA viruses (NSVs) include many important human pathogens, such as influenza virus, Ebola virus, and rabies virus. One of the unique characteristics that NSVs share is the assembly of the nucleocapsid and its role in viral RNA synthesis. In NSVs, the single strand RNA genome is encapsidated in the line...

journal_title：Viruses

authors： Luo M,Terrell JR,Mcmanus SA

更新日期：2020-07-30 00:00:00

abstract：:The most highly expressed protein during the productive phase of the human papillomavirus (HPV) life cycle is E1^E4. Its full role during infection remains to be established. HPV E1^E4 is expressed during both the early and late stages of the virus life cycle and contributes to viral genome amplification. In an attemp...

journal_title：Viruses

authors： Biryukov J,Myers JC,McLaughlin-Drubin ME,Griffin HM,Milici J,Doorbar J,Meyers C

更新日期：2017-12-19 00:00:00

abstract：:Fruit trees, such as apricot trees, are constantly exposed to the attack of viruses. As they are propagated in a vegetative way, this risk is present not only in the field, where they remain for decades, but also during their propagation. Metagenomic diagnostic methods, based on next generation sequencing (NGS), offer...

journal_title：Viruses

authors： Baráth D,Jaksa-Czotter N,Molnár J,Varga T,Balássy J,Szabó LK,Kirilla Z,Tusnády GE,Preininger É,Várallyay É

更新日期：2018-06-11 00:00:00

abstract：:Vaccination is the most effective means to prevent influenza virus infection, although current approaches are associated with suboptimal efficacy. Here, we generated virus-like particles (VLPs) composed of the hemagglutinin (HA), neuraminidase (NA) and matrix protein (M1) of A/Changchun/01/2009 (H1N1) with or without ...

journal_title：Viruses

authors： Ji X,Ren Z,Xu N,Meng L,Yu Z,Feng N,Sang X,Li S,Li Y,Wang T,Zhao Y,Wang H,Zheng X,Jin H,Li N,Yang S,Cao J,Liu W,Gao Y,Xia X

更新日期：2016-04-21 00:00:00

abstract：:Influenza A viruses (IAVs) harbor a segmented RNA genome that is organized into eight distinct viral ribonucleoprotein (vRNP) complexes. Although a segmented genome may be a major advantage to adapt to new host environments, it comes at the cost of a highly sophisticated genome packaging mechanism. Newly synthesized v...

journal_title：Viruses

authors： Giese S,Bolte H,Schwemmle M

更新日期：2016-06-17 00:00:00

abstract：:In July 2018, a novel avian influenza virus (A/Mandarin duck/South Korea/KNU18-12/2018(H11N9)) was isolated from Mandarin ducks in South Korea. Phylogenetic and molecular analyses were conducted to characterize the genetic origins of the H11N9 strain. Phylogenetic analysis indicated that eight gene segments of strain ...

journal_title：Viruses

authors： Tuong HT,Nguyen NM,Sung HW,Park H,Yeo SJ

更新日期：2020-02-12 00:00:00

abstract：:Most cases of hemorrhagic fever with renal syndrome (HFRS) in Europe are caused by the Puumala hantavirus (PUUV). Typical features of the disease are increased vascular permeability, acute kidney injury (AKI), and thrombocytopenia. YKL-40 is an inflammatory glycoprotein involved in various forms of acute and chronic i...

journal_title：Viruses

authors： Outinen TK,Mantula P,Jaatinen P,Hämäläinen M,Moilanen E,Vaheri A,Huhtala H,Mäkelä S,Mustonen J

更新日期：2019-08-21 00:00:00

abstract：:Arboviruses continue to be a significant global health concern. The unbiased metagenomic analyses of mosquito-borne and mosquito-specific viruses are useful to understand viral diversity and for the surveillance of pathogens of medical and veterinary importance. Metagenomic analysis was conducted on 6368 mosquitoes (7...

journal_title：Viruses

authors： Sanborn MA,Klein TA,Kim HC,Fung CK,Figueroa KL,Yang Y,Asafo-Adjei EA,Jarman RG,Hang J

更新日期：2019-03-05 00:00:00

abstract：:Hantaviruses, members of the order Bunyavirales, family Hantaviridae, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year. The spectrum of disease associated with hantavirus infection include hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrom...

journal_title：Viruses

authors： Brocato RL,Hooper JW

更新日期：2019-07-04 00:00:00

abstract：:Persistent infection by human papillomaviruses (HPVs), small, double-stranded DNA viruses that infect keratinocytes of the squamous epithelia, can lead to the development of cervical and other cancers. The viral oncoprotein E7 contributes to viral persistence in part by regulating host gene expression through binding ...

journal_title：Viruses

authors： Rice S,Kim SM,Rodriguez C,Songock W,Raikhy G,Lopez R,Henderson L,Yusufji A,Bodily J

更新日期：2020-03-13 00:00:00

abstract：:The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of HBV immunity in pat...

journal_title：Viruses

authors： Bertoletti A,Tan AT,Gehring AJ

更新日期：2009-09-01 00:00:00

abstract：:The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS)...

journal_title：Viruses

authors： Jin Y,Yang H,Ji W,Wu W,Chen S,Zhang W,Duan G

更新日期：2020-03-27 00:00:00

abstract：:Virus diseases greatly affect oilseed rape (Brassica napus) production. Investigating antiviral genes may lead to the development of disease-resistant varieties of oilseed rape. In this study, we examined the effects of the suppressor of gene silencing 3 in Brassica napus (BnSGS3, a putative antiviral gene) with diffe...

journal_title：Viruses

authors： Chen Q,Wang J,Hou M,Liu S,Huang J,Cai L

更新日期：2015-07-27 00:00:00

abstract：:: Rabies virus (RABV) is the only lyssavirus known to be present within the Caribbean. The island of Trinidad, is richly diverse in chiropteran fauna and endemic for bat-transmitted rabies with low RABV isolation rates observed in this population. We aimed to determine the seroprevalence of rabies virus neutralizing a...

journal_title：Viruses

authors： Seetahal JFR,Greenberg L,Satheshkumar PS,Sanchez-Vazquez MJ,Legall G,Singh S,Ramkissoon V,Schountz T,Munster V,Oura CAL,Carrington CVF

更新日期：2020-02-05 00:00:00

abstract：:The ability of the host to trigger apoptosis in infected cells is perhaps the most powerful tool by which viruses can be cleared from the host organism. To avoid elimination by this mechanism, human papillomaviruses (HPV) have developed several mechanisms that enable the cells they infect to elude both extrinsic and i...

journal_title：Viruses

authors： Yuan CH,Filippova M,Duerksen-Hughes P

更新日期：2012-12-18 00:00:00

abstract：:The degree of antigenic drift in swine influenza A viruses (swIAV) has historically been regarded as minimal compared to that of human influenza A virus strains. However, as surveillance activities on swIAV have increased, more isolates have been characterized, revealing a high level of genetic and antigenic differenc...

journal_title：Viruses

authors： Ryt-Hansen P,Pedersen AG,Larsen I,Kristensen CS,Krog JS,Wacheck S,Larsen LE

更新日期：2020-02-23 00:00:00

abstract：:Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral mechanisms. Recent studies reveal that IFN dysregulation is key to determine COVID-19 pathogenesis. Effective IFN stimulation or prophylactic administration of IFNs at the early stage prior to severe COVID-19 may elicit an a...

journal_title：Viruses

authors： Lopez L,Sang PC,Tian Y,Sang Y

更新日期：2020-12-13 00:00:00