Vaccinia Virus Natural Infections in Brazil: The Good, the Bad, and the Ugly.

abstract：:Exosomes are extracellular vesicles released upon fusion of multivesicular bodies(MVBs) with the cellular plasma membrane. They originate as intraluminal vesicles (ILVs) during the process of MVB formation. Exosomes were shown to contain selectively sorted functional proteins, lipids, and RNAs, mediating cell-to-cell ...

journal_title：Viruses

authors： Alenquer M,Amorim MJ

更新日期：2015-09-17 00:00:00

abstract：:Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal. The host range and tissue tropism are largely determined by the coronaviral spike protein, which initiates cellular infection b...

journal_title：Viruses

authors： Haake C,Cook S,Pusterla N,Murphy B

更新日期：2020-09-13 00:00:00

abstract：:Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, the bank vole, is rather continuous. A missing pi...

journal_title：Viruses

authors： Castel G,Couteaudier M,Sauvage F,Pons JB,Murri S,Plyusnina A,Pontier D,Cosson JF,Plyusnin A,Marianneau P,Tordo N

更新日期：2015-10-22 00:00:00

abstract：:Respiratory viruses cause disease in humans characterized by an abrupt onset of symptoms. Studies in humans and animal models have shown that symptoms are not immediate and appear days or even weeks after infection. Since the initial symptoms are a manifestation of virus recognition by elements of the innate immune re...

journal_title：Viruses

authors： Hermesh T,Moltedo B,López CB,Moran TM

更新日期：2010-11-01 00:00:00

abstract：:Seoul virus (SEOV) is a zoonotic orthohantavirus carried by black and brown rats, and can cause hemorrhagic fever with renal syndrome in humans. Human cases of SEOV virus infection have most recently been reported in the USA, United Kingdom, France and the Netherlands and were primarily associated with contact with pe...

journal_title：Viruses

authors： Maas M,van Heteren M,de Vries A,Kuiken T,Hoornweg T,Veldhuis Kroeze E,Rockx B

更新日期：2019-06-07 00:00:00

abstract：:Influenza A viruses (IAVs) are highly contagious pathogens infecting human and numerous animals. The viruses cause millions of infection cases and thousands of deaths every year, thus making IAVs a continual threat to global health. Upon IAV infection, host innate immune system is triggered and activated to restrict v...

journal_title：Viruses

authors： Zhang Y,Xu Z,Cao Y

更新日期：2020-03-29 00:00:00

abstract：:The Human immunodeficiency virus-1 (HIV-1) accessory protein Vpu modulates numerous proteins, including the host proteins CD4 and BST-2/tetherin. Vpu interacts with the Skp, Cullin, F-Box (SCF) ubiquitin ligase through interactions with the F-Box protein βTrCP (1 and/or 2). This interaction is dependent on phosphoryla...

journal_title：Viruses

authors： Song YE,Cyburt D,Lucas TM,Gregory DA,Lyddon TD,Johnson MC

更新日期：2018-10-19 00:00:00

abstract：:Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer than 5% of HBV-infected adults (but up to 90% of HBV-infected infants and children) develop chronic HBV infection as indicated by contin...

journal_title：Viruses

authors： Megahed FAK,Zhou X,Sun P

更新日期：2020-03-05 00:00:00

abstract：:Since 2015, severe hydropericardium-hepatitis syndrome (HHS), caused by a highly pathogenic fowl adenovirus 4 (FAdV-4), emerged in China. In our previous study, the FAdV-4 has been identified as a novel genotype with a unique 1966-bp nucleotide deletion (1966Del) between open reading frame 42 and 43. In this study, th...

journal_title：Viruses

authors： Pan Q,Wang J,Gao Y,Cui H,Liu C,Qi X,Zhang Y,Wang Y,Wang X

更新日期：2018-09-13 00:00:00

abstract：:Nasopharyngeal cancer (NPC) is associated with Epstein Barr virus (EBV) infection. However different viral strains have been implicated in NPC worldwide. This study aimed to detect and characterize EBV in patients diagnosed with NPC in Ghana. A total of 55 patients diagnosed with NPC by CT scan and endoscopy were age-...

journal_title：Viruses

authors： Ayee R,Ofori MEO,Tagoe EA,Languon S,Searyoh K,Armooh L,Bilson-Amoah E,Baidoo K,Kitcher E,Wright E,Quaye O

更新日期：2020-07-16 00:00:00

abstract：:Type-I interferons (IFN-I) play an important role in the innate immune response to several retroviruses. They seem to be effective in controlling the in vivo infection, though many of the clinical signs of retroviral infection may be due to their continual presence which over-stimulates the immune system and activates...

journal_title：Viruses

authors： Gómez-Lucía E,Collado VM,Miró G,Doménech A

更新日期：2009-12-01 00:00:00

abstract：:Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related Old-World mammarenaviruses. LASV causes severe hemorrhagic fever with high mortality in humans, whereas no case of MOPV infection has been reported. Comparing MOPV and LASV is a powerful strategy to unravel pathogenic mechanisms that occur during the c...

journal_title：Viruses

authors： Baillet N,Krieger S,Journeaux A,Caro V,Tangy F,Vidalain PO,Baize S

更新日期：2019-03-23 00:00:00

abstract：:Fruit trees, such as apricot trees, are constantly exposed to the attack of viruses. As they are propagated in a vegetative way, this risk is present not only in the field, where they remain for decades, but also during their propagation. Metagenomic diagnostic methods, based on next generation sequencing (NGS), offer...

journal_title：Viruses

authors： Baráth D,Jaksa-Czotter N,Molnár J,Varga T,Balássy J,Szabó LK,Kirilla Z,Tusnády GE,Preininger É,Várallyay É

更新日期：2018-06-11 00:00:00

abstract：:The strong association between Varroa destructor, deformed wing virus (DWV), and high overwintering colony losses (OCL) of honey bees is well established. Three DWV master variants (DWV-A, -B, and -C) have been described, and their role in colony mortality remains an open question. Therefore, the aim of this study is ...

journal_title：Viruses

authors： Kevill JL,de Souza FS,Sharples C,Oliver R,Schroeder DC,Martin SJ

更新日期：2019-05-09 00:00:00

abstract：:Pectobacterium atrosepticum is a phytopathogen of economic importance as it is the causative agent of potato blackleg and soft rot. Here we describe the Pectobacterium phage vB_PatP_CB5 (abbreviated as CB5), which specifically infects the bacterium. The bacteriophage is characterized in detail and TEM micrographs indi...

journal_title：Viruses

authors： Buttimer C,Lucid A,Neve H,Franz CMAP,O'Mahony J,Turner D,Lavigne R,Coffey A

更新日期：2018-07-26 00:00:00

abstract：:The DNA damage response (DDR) is a complex signalling network activated when DNA is altered by intrinsic or extrinsic agents. DDR plays important roles in genome stability and cell cycle regulation, as well as in tumour transformation. Viruses have evolved successful life cycle strategies in order to ensure a chronic ...

journal_title：Viruses

authors： Bordignon V,Di Domenico EG,Trento E,D'Agosto G,Cavallo I,Pontone M,Pimpinelli F,Mariani L,Ensoli F

更新日期：2017-12-19 00:00:00

abstract：:While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. Among 1779 bat samples collected in China, diverse coronaviruses were detected in 32 samples from five different bat species by RT-PCR. Two novel alpha...

journal_title：Viruses

authors： Lau SKP,Wong ACP,Zhang L,Luk HKH,Kwok JSL,Ahmed SS,Cai JP,Zhao PSH,Teng JLL,Tsui SKW,Yuen KY,Woo PCY

更新日期：2019-05-07 00:00:00

abstract：:Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understanding of the pathog...

journal_title：Viruses

authors： Lhomme S,Marion O,Abravanel F,Chapuy-Regaud S,Kamar N,Izopet J

更新日期：2016-08-05 00:00:00

abstract：BACKGROUND:Zika virus is a mosquito-borne flavivirus responsible for recent outbreaks of epidemic proportions in Latin America. Sexual transmission of the virus has been reported in 13 countries and may be an important route of infection. Sexual transmission of ZIKV has mostly been male-to-female, and persistence of vi...

journal_title：Viruses

authors： Mlera L,Bloom ME

更新日期：2019-01-09 00:00:00

abstract：:Present in many cell types, non-degradative secretory autophagy is a newly discovered pathway in which autophagosomes fuse with the plasma membrane instead of lysosomes. Surprisingly, some viruses exploit secretory autophagy to exit cells non-lytically, shedding into the extracellular environment as particle populatio...

journal_title：Viruses

authors： Mutsafi Y,Altan-Bonnet N

更新日期：2018-03-20 00:00:00

abstract：:Our previous studies have demonstrated that haploid AAV vectors made from capsids of two different serotypes induced high transduction and prevented serotype-specific antibody binding. In this study, we explored the transduction efficiency of several haploid viruses, which were made from the VP1/VP2 of one serotype an...

journal_title：Viruses

authors： Chai Z,Zhang X,Dobbins AL,Frost EA,Samulski RJ,Li C

更新日期：2019-12-09 00:00:00

abstract：:Type I interferon (IFN-I) is the first line of mammalian host defense against viral infection. To counteract this, the flaviviruses, like other viruses, have encoded a variety of antagonists, and use a multi-layered molecular defense strategy to establish their infections. Among the most potent antagonists is non-stru...

journal_title：Viruses

authors： Thurmond S,Wang B,Song J,Hai R

更新日期：2018-12-14 00:00:00

abstract：:Sandfly-borne phleboviruses pathogenic to humans, such as Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV), are endemic in the Mediterranean region. In France, several autochthonous cases of TOSV infection have been described, causing either meningitis or encephalitis. The aim of the present study was to i...

journal_title：Viruses

authors： Masse S,Ayhan N,Capai L,Bosseur F,de Lamballerie X,Charrel R,Falchi A

更新日期：2019-09-04 00:00:00

abstract：:To further understanding of the structure and morphology of the Orthohantavirus, family Hantaviridae, we have employed cryo-electron microscopy (cryo-EM) for three New World hantaviruses: Andes (ANDV), Sin Nombre (SNV), and Black Creek Canal (BCCV). Building upon our prior cryo-EM and cryo-tomography study of the Old ...

journal_title：Viruses

authors： Parvate A,Williams EP,Taylor MK,Chu YK,Lanman J,Saphire EO,Jonsson CB

更新日期：2019-09-16 00:00:00

abstract：:During the early stages of human papillomavirus (HPV) infections, the innate immune system creates a pro-inflammatory microenvironment by recruiting innate immune cells to eliminate the infected cells, initiating an effective acquired immune response. However, HPV exhibits a wide range of strategies for evading immune...

journal_title：Viruses

authors： Amador-Molina A,Hernández-Valencia JF,Lamoyi E,Contreras-Paredes A,Lizano M

更新日期：2013-10-28 00:00:00

abstract：:Phylodynamic inference is a pivotal tool in understanding transmission dynamics of viral outbreaks. These analyses are strongly guided by the input of an epidemiological model as well as sequence data that must contain sufficient intersequence variability in order to be informative. These criteria, however, may not be...

journal_title：Viruses

authors： Lam A,Duchene S

更新日期：2021-01-08 00:00:00

abstract：:The Iridoviridae family are large viruses (∼120-200 nm) that contain a linear double-stranded DNA genome. The genomic size of Iridoviridae family members range from 105,903 bases encoding 97 open reading frames (ORFs) for frog virus 3 to 212,482 bases encoding 211 ORFs for Chilo iridescent virus. The family Iridovirid...

journal_title：Viruses

authors： Eaton HE,Ring BA,Brunetti CR

更新日期：2010-07-01 00:00:00

abstract：:The ability of the host to trigger apoptosis in infected cells is perhaps the most powerful tool by which viruses can be cleared from the host organism. To avoid elimination by this mechanism, human papillomaviruses (HPV) have developed several mechanisms that enable the cells they infect to elude both extrinsic and i...

journal_title：Viruses

authors： Yuan CH,Filippova M,Duerksen-Hughes P

更新日期：2012-12-18 00:00:00

abstract：:Tetherin is an interferon-induced, intrinsic cellular response factor that blocks release of numerous viruses, including Ebola virus, from infected cells. As with many viruses targeted by host factors, Ebola virus employs a tetherin antagonist, the viral glycoprotein (EboGP), to counteract restriction and promote viru...

journal_title：Viruses

authors： Vande Burgt NH,Kaletsky RL,Bates P

更新日期：2015-10-26 00:00:00

abstract：:Noroviruses are a leading cause of gastroenteritis worldwide. Although infections in healthy individuals are self-resolving, immunocompromised individuals are at risk for chronic disease and severe complications. Chronic norovirus infections in immunocompromised hosts are often characterized by long-term virus sheddin...

journal_title：Viruses

authors： Davis A,Cortez V,Grodzki M,Dallas R,Ferrolino J,Freiden P,Maron G,Hakim H,Hayden RT,Tang L,Huys A,Kolawole AO,Wobus CE,Jones MK,Karst SM,Schultz-Cherry S

更新日期：2020-06-05 00:00:00