Abstract：
:Present in many cell types, non-degradative secretory autophagy is a newly discovered pathway in which autophagosomes fuse with the plasma membrane instead of lysosomes. Surprisingly, some viruses exploit secretory autophagy to exit cells non-lytically, shedding into the extracellular environment as particle populations contained within vesicles. As a result, this significantly enhances the infectivity of these viruses. In this paper, this novel cellular exit pathway is highlighted and its advantages for viral transmission discussed.
journal_name
Virusesjournal_title
Virusesauthors
Mutsafi Y,Altan-Bonnet Ndoi
10.3390/v10030139subject
Has Abstractpub_date
2018-03-20 00:00:00issue
3issn
1999-4915pii
v10030139journal_volume
10pub_type
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