CD8 and CD4 T cells in west nile virus immunity and pathogenesis.

abstract：:Bovine viral diarrhea virus (BVDV) is an important pathogen belonging to the Pestivirus genus, Flaviviridae family, which comprises viral species that causes an economic impact in animal production. Cattle are the natural host of BVDV and the main source of infection for pigs and other animal species. Due to its antig...

journal_title：Viruses

authors： de Oliveira LG,Mechler-Dreibi ML,Almeida HMS,Gatto IRH

更新日期：2020-05-31 00:00:00

abstract：:The most highly expressed protein during the productive phase of the human papillomavirus (HPV) life cycle is E1^E4. Its full role during infection remains to be established. HPV E1^E4 is expressed during both the early and late stages of the virus life cycle and contributes to viral genome amplification. In an attemp...

journal_title：Viruses

authors： Biryukov J,Myers JC,McLaughlin-Drubin ME,Griffin HM,Milici J,Doorbar J,Meyers C

更新日期：2017-12-19 00:00:00

abstract：:Lactococcus lactis is one of the most important bacteria in dairy fermentations, being used in the production of cheese and buttermilk. The processes are vulnerable to phage attacks, and undefined mixtures of lactococcal strains are often used to reduce the risk of bacteriophage caused fermentation failure. Other prev...

journal_title：Viruses

authors： Frantzen CA,Holo H

更新日期：2019-05-16 00:00:00

abstract：:BST-2 or tetherin is a host cell restriction factor that prevents the budding of enveloped viruses at the cell surface, thus impairing the viral spread. Several countermeasures to evade this antiviral factor have been positively selected in retroviruses: the human immunodeficiency virus type 2 (HIV-2) relies on the en...

journal_title：Viruses

authors： Dufrasne FE,Lombard C,Goubau P,Ruelle J

更新日期：2016-10-14 00:00:00

abstract：:We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection p...

journal_title：Viruses

authors： Andreo V,Neteler M,Rocchini D,Provensal C,Levis S,Porcasi X,Rizzoli A,Lanfri M,Scavuzzo M,Pini N,Enria D,Polop J

更新日期：2014-01-14 00:00:00

abstract：:Using different prion strains, such as the variant Creutzfeldt-Jakob disease agent and the atypical bovine spongiform encephalopathy agents, and using transgenic mice expressing human or bovine prion protein, we assessed the reliability of protein misfolding cyclic amplification (PMCA) to model interspecies and geneti...

journal_title：Viruses

authors： Levavasseur E,Privat N,Martin JC,Simoneau S,Baron T,Flan B,Torres JM,Haïk S

更新日期：2014-10-02 00:00:00

abstract：:Since the development of methods for inserting and expressing genes in baculoviruses, a line of research has focused on developing recombinant baculoviruses that express insecticidal peptides and proteins. These recombinant viruses have been engineered with the goal of improving their pesticidal potential by shortenin...

journal_title：Viruses

authors： Kroemer JA,Bonning BC,Harrison RL

更新日期：2015-01-21 00:00:00

abstract：:At the end of 2019, a new disease appeared and spread all over the world, the COVID-19, produced by the coronavirus SARS-CoV-2. As a consequence of this worldwide health crisis, the scientific community began to redirect their knowledge and resources to fight against it. Here we summarize the recent research on viruse...

journal_title：Viruses

authors： Fernandez-Garcia L,Pacios O,González-Bardanca M,Blasco L,Bleriot I,Ambroa A,López M,Bou G,Tomás M

更新日期：2020-10-16 00:00:00

abstract：:Mechanistic models are critical for our understanding of both within-host dynamics (i.e., pathogen replication and immune system processes) and among-host dynamics (i.e., transmission). Within-host models, however, are not often fit to experimental data, which can serve as a robust method of hypothesis testing and hyp...

journal_title：Viruses

authors： Mihaljevic JR,Greer AL,Brunner JL

更新日期：2019-04-27 00:00:00

abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

journal_title：Viruses

authors： Mishra P,Furey C,Balaraman V,Fraser MJ

更新日期：2016-06-10 00:00:00

abstract：:Herpesviridae comprise a large family of enveloped DNA viruses all of whom employ orthologs of the same three glycoproteins, gB, gH and gL. Additionally, herpesviruses often employ accessory proteins to bind receptors and/or bind the heterodimer gH/gL or even to determine cell tropism. Sorting out how these proteins f...

journal_title：Viruses

authors： Eisenberg RJ,Atanasiu D,Cairns TM,Gallagher JR,Krummenacher C,Cohen GH

更新日期：2012-05-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer than 5% of HBV-infected adults (but up to 90% of HBV-infected infants and children) develop chronic HBV infection as indicated by contin...

journal_title：Viruses

authors： Megahed FAK,Zhou X,Sun P

更新日期：2020-03-05 00:00:00

abstract：:Enteric viral co-infections, infections involving more than one virus, have been reported for a diverse group of etiological agents, including rotavirus, norovirus, astrovirus, adenovirus, and enteroviruses. These pathogens are causative agents for acute gastroenteritis and diarrheal disease in immunocompetent and imm...

journal_title：Viruses

authors： Makimaa H,Ingle H,Baldridge MT

更新日期：2020-08-18 00:00:00

abstract：:West Nile virus (WNV) is a member of the genus Flavivirus in the family Flaviviridae. Flaviviruses replicate in the cytoplasm of infected cells and modify the host cell environment. Although much has been learned about virion structure and virion-endosomal membrane fusion, the cell receptor(s) used have not been defin...

journal_title：Viruses

authors： Brinton MA

更新日期：2013-12-27 00:00:00

abstract：:MicroRNAs (miRNAs) are non-coding but functional RNA molecules of 21-25 nucleotides in length. MiRNAs play significant regulatory roles in diverse plant biological processes. In order to decipher the relationship between nbe-miR1919c-5p and the accumulations of tobacco curly shoot virus (TbCSV) and its betasatellite (...

journal_title：Viruses

authors： Du J,Wu R,Liu Z,Sun M,Ghanem H,Li M,Wu G,Qing L

更新日期：2020-04-01 00:00:00

abstract：:Metagenomics studies have accelerated the discovery of novel or divergent viruses of the honey bee. However, most of these studies predominantly focused on RNA viruses, and many suffer from the relatively low abundance of viral nucleic acids in the samples (i.e., compared to that of the host). Here, we explored the vi...

journal_title：Viruses

authors： Gebremedhn H,Deboutte W,Schoonvaere K,Demaeght P,De Smet L,Amssalu B,Matthijnssens J,de Graaf DC

更新日期：2020-10-27 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is a complex retrovirus that infects CD4+ T cells and causes adult T-cell leukemia/lymphoma (ATLL) in 3%-5% of infected individuals after a long latent period. HTLV-1 Tax is a trans-activating protein that regulates viral gene expression and also modulates cellular signaling...

journal_title：Viruses

authors： Lavorgna A,Harhaj EW

更新日期：2014-10-23 00:00:00

abstract：:Campylobacter jejuni is a frequent foodborne pathogen of humans. As C. jejuni infections commonly arise from contaminated poultry, phage treatments have been proposed to reduce the C. jejuni load on farms to prevent human infections. While a prior report documented the transcriptome of C. jejuni phages during the carr...

journal_title：Viruses

authors： Sacher JC,Flint A,Butcher J,Blasdel B,Reynolds HM,Lavigne R,Stintzi A,Szymanski CM

更新日期：2018-06-16 00:00:00

abstract：:The DNA damage response (DDR) is a complex signalling network activated when DNA is altered by intrinsic or extrinsic agents. DDR plays important roles in genome stability and cell cycle regulation, as well as in tumour transformation. Viruses have evolved successful life cycle strategies in order to ensure a chronic ...

journal_title：Viruses

authors： Bordignon V,Di Domenico EG,Trento E,D'Agosto G,Cavallo I,Pontone M,Pimpinelli F,Mariani L,Ensoli F

更新日期：2017-12-19 00:00:00

abstract：:The human cytomegalovirus (HCMV)-encoded protein kinase, pUL97, is considered a cyclin-dependent kinase (CDK) ortholog, due to shared structural and functional characteristics. The primary mechanism of CDK activation is binding to corresponding cyclins, including cyclin T1, which is the usual regulatory cofactor of CD...

journal_title：Viruses

authors： Graf L,Webel R,Wagner S,Hamilton ST,Rawlinson WD,Sticht H,Marschall M

更新日期：2013-12-18 00:00:00

abstract：:The Protoparvovirus (PtPV) genus of the Parvoviridae family of viruses includes important animal pathogens and reference molecular models for the entire family. Some virus members of the PtPV genus have arisen as promising tools to treat tumoral processes, as they exhibit marked oncotropism and oncolytic activities wh...

journal_title：Viruses

authors： Ros C,Bayat N,Wolfisberg R,Almendral JM

更新日期：2017-10-26 00:00:00

abstract：:Zika virus recently re-emerged and caused global outbreaks mainly in Central Africa, Southeast Asia, the Pacific Islands and in Central and South America. Even though there is a declining trend, the virus continues to spread throughout different geographical regions of the world. Since its re-emergence in 2015, massiv...

journal_title：Viruses

authors： Alves MP,Vielle NJ,Thiel V,Pfaender S

更新日期：2018-10-30 00:00:00

abstract：:Different developmental stages of Artemia spp. (metanauplii, juveniles and adults) were bath-challenged with two isolates of the Lymphocystis disease virus (LCDV), namely, LCDV SA25 (belonging to the species Lymphocystis disease virus 3) and ATCC VR-342 (an unclassified member of the genus Lymphocystivirus). Viral qua...

journal_title：Viruses

authors： Valverde EJ,Labella AM,Borrego JJ,Castro D

更新日期：2019-06-01 00:00:00

abstract：:Influenza A virus (IAV) in swine, so-called swine influenza A virus (swIAV), causes respiratory illness in pigs around the globe. In Danish pig herds, a H1N2 subtype named H1N2dk is one of the main circulating swIAV. In this cohort study, the infection dynamic of swIAV was evaluated in a Danish pig herd by sampling an...

journal_title：Viruses

authors： Bhatta TR,Ryt-Hansen P,Nielsen JP,Larsen LE,Larsen I,Chamings A,Goecke NB,Alexandersen S

更新日期：2020-09-10 00:00:00

abstract：:The impact of topical applications of deltamethrin and ivermectin to cattle on Culicoides spp. landing and blood-feeding was studied in this work using sticky traps mounted on Friesian heifers' backs. There was no effect of the insecticides on total numbers of Culicoides trapped or the proportion engorged. Deltamethri...

journal_title：Viruses

authors： Murchie AK,Thompson GM,Clawson S,Brown A,Gordon AW,Jess S

更新日期：2019-08-08 00:00:00

abstract：:The levels of vascular endothelial growth factor-A (VEGF) were estimated in 102 serum samples from 63 hospitalized Greek patients with hemorrhagic fever with renal syndrome (HFRS) caused by Dobrava/Belgrade virus. Significantly higher VEGF levels were seen in the severe when compared with non-severe cases (mean values...

journal_title：Viruses

authors： Tsergouli K,Papa A

更新日期：2013-12-10 00:00:00

abstract：:African swine fever is a highly lethal hemorrhagic fever of Suidae, threatening pig production globally. Suidae can be infected by different ways like ingestion of contaminated feed, direct contact with infected animals or fomites, and biting by infected soft tick bites. As already described, European soft ticks (Orni...

journal_title：Viruses

authors： Pereira De Oliveira R,Hutet E,Duhayon M,Guionnet JM,Paboeuf F,Vial L,Le Potier MF

更新日期：2020-03-11 00:00:00

abstract：:Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understanding of the pathog...

journal_title：Viruses

authors： Lhomme S,Marion O,Abravanel F,Chapuy-Regaud S,Kamar N,Izopet J

更新日期：2016-08-05 00:00:00

abstract：:The development of high-throughput technologies allows for evaluating gene expression at the whole-genome level. Together with proteomic and metabolomic studies, these analyses have resulted in the identification of plant genes whose function or expression is altered as a consequence of pathogen attacks. Members of th...

journal_title：Viruses

authors： Czosnek H,Eybishtz A,Sade D,Gorovits R,Sobol I,Bejarano E,Rosas-Díaz T,Lozano-Durán R

更新日期：2013-03-22 00:00:00

abstract：:Zika virus (ZIKV) is an important arbovirus, responsible for recent outbreaks of Guillain Barré Syndrome and Congenital Zika Syndrome (CZS). After thousands of CZS cases, ZIKV is under constant surveillance in Brazil. Reliable and robust detection techniques are required to minimize the influence of host inhibitors fr...

journal_title：Viruses

authors： Almeida PR,Eisen AKA,Demoliner M,Spilki FR

更新日期：2020-07-30 00:00:00