Vascular endothelial growth factor levels in dobrava/belgrade virus infections.

abstract：:The Gammacoronavirus infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not replicate in cell culture, making the study of their basic virolo...

journal_title：Viruses

authors： Stevenson-Leggett P,Keep S,Bickerton E

更新日期：2020-09-29 00:00:00

abstract：:Dengue virus (DENV) is the most widespread arthropod-borne virus, with the number and severity of outbreaks increasing worldwide in recent decades. Dengue is caused by genetically distinct serotypes, DENV-1-4. Here, we present data on DENV-1, isolated from patients with dengue fever during an outbreak in Senegal and M...

journal_title：Viruses

authors： Dieng I,Cunha M,Diagne MM,Sembène PM,Zanotto PMA,Faye O,Faye O,Sall AA

更新日期：2021-01-04 00:00:00

abstract：:To further understanding of the structure and morphology of the Orthohantavirus, family Hantaviridae, we have employed cryo-electron microscopy (cryo-EM) for three New World hantaviruses: Andes (ANDV), Sin Nombre (SNV), and Black Creek Canal (BCCV). Building upon our prior cryo-EM and cryo-tomography study of the Old ...

journal_title：Viruses

authors： Parvate A,Williams EP,Taylor MK,Chu YK,Lanman J,Saphire EO,Jonsson CB

更新日期：2019-09-16 00:00:00

abstract：:Viroids are small, non-coding, circular RNA molecules that infect plants. Different hypotheses for their evolutionary origin have been put forward, such as an early emergence in a precellular RNA World or several de novo independent evolutionary origins in plants. Here, we discuss the plausibility of de novo emergence...

journal_title：Viruses

authors： Catalán P,Elena SF,Cuesta JA,Manrubia S

更新日期：2019-05-09 00:00:00

abstract：:The Pneumoviridae family includes human metapneumovirus (HMPV) and human orthopneumovirus, which is also known as a respiratory syncytial virus (HRSV). These are large enveloped, negative single-strand RNA viruses. HMPV and HRSV are the human members, which commonly infect children. HMPV, which was discovered in 2001,...

journal_title：Viruses

authors： Diab M,Schmiedel D,Seidel E,Bacharach E,Mandelboim O

更新日期：2020-07-20 00:00:00

abstract：:Kobuviruses comprise three species, the Aichivirus A, Aichivirus B, and Aichivirus C (porcine kobuvirus). Porcine kobuvirus is endemic to pig farms and is not restricted geographically but, rather, is distributed worldwide. The complete genomic sequences of four porcine kobuvirus strains isolated during a diarrhea out...

journal_title：Viruses

authors： Fan S,Sun H,Ying Y,Gao X,Wang Z,Yu Y,Li Y,Wang T,Yu Z,Yang S,Zhao Y,Qin C,Gao Y,Xia X

更新日期：2013-10-18 00:00:00

abstract：:Neuraminidase inhibitors (NAIs) are vital in managing seasonal and pandemic influenza infections. NAI susceptibilities of virus isolates (n = 5540) collected during the 2008-2009 influenza season were assessed in the chemiluminescent neuraminidase inhibition (NI) assay. Box-and-whisker plot analyses of log-transformed...

journal_title：Viruses

authors： Okomo-Adhiambo M,Sleeman K,Ballenger K,Nguyen HT,Mishin VP,Sheu TG,Smagala J,Li Y,Klimov AI,Gubareva LV

更新日期：2010-10-01 00:00:00

abstract：:Monkeypox is a smallpox-like illness that can be accompanied by a range of significant medical complications. To date there are no standard or optimized guidelines for the clinical management of monkeypox (MPX) patients, particularly in low-resource settings. Consequently, patients can experience protracted illness an...

journal_title：Viruses

authors： Reynolds MG,McCollum AM,Nguete B,Shongo Lushima R,Petersen BW

更新日期：2017-12-12 00:00:00

abstract：:Specific chromatin immunoprecipitation of salt-fractionated infected cell extracts has demonstrated that the CCCTC-binding factor (CTCF), a highly conserved, 11-zinc-finger DNA-binding protein with known roles in cellular and viral genome organization and gene expression, specifically binds the genome of Minute Virus ...

journal_title：Viruses

authors： Boftsi M,Majumder K,Burger LR,Pintel DJ

更新日期：2020-11-30 00:00:00

abstract：:A metagenomic study was performed on 498 female and 40 male Aedes albopictus mosquitos collected in August and September 2019 in Ticino, a region in southern Switzerland, to address the question regarding the risk of the local transmission of zoonotic viruses. A total of 13 viruses from seven different virus families ...

journal_title：Viruses

authors： Kubacki J,Flacio E,Qi W,Guidi V,Tonolla M,Fraefel C

更新日期：2020-08-24 00:00:00

abstract：:Hepatitis B surface antigen (HBsAg) promotes persistent hepatitis B virus (HBV) infection. It primarily corresponds to small (S) envelope protein secreted as subviral particles. We previously found that genotype D clones expressed less S protein than genotype A clones but showed higher extracellular/intracellular rati...

journal_title：Viruses

authors： Wang Q,Fu S,Zhang J,Yuan Q,Li J,Xia N,Wen YM,Wang Y,Tong S

更新日期：2020-09-01 00:00:00

abstract：:Exosomes are membrane-enclosed vesicles actively released into the extracellular space, whose content reflect the physiological/pathological state of the cells they originate from. These vesicles participate in cell-to-cell communication and transfer of biologically active proteins, lipids, and RNAs. Their role in vir...

journal_title：Viruses

authors： Chahar HS,Bao X,Casola A

更新日期：2015-06-19 00:00:00

abstract：:Insectivorous bats are speculated to be ancestral hosts of Middle-East respiratory syndrome (MERS) coronavirus (CoV). MERS-CoV causes disease in humans with thirty-five percent fatality, and has evolved proteins that counteract human antiviral responses. Since bats experimentally infected with MERS-CoV do not develop ...

journal_title：Viruses

authors： Banerjee A,Falzarano D,Rapin N,Lew J,Misra V

更新日期：2019-02-13 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the etiological agent for a serious lower respiratory tract disease responsible for close to 200,000 annual deaths worldwide. The first infection is generally most severe, while re-infections usually associate with a milder disease. This observation and the finding that re-infecti...

journal_title：Viruses

authors： Rudraraju R,Jones BG,Sealy R,Surman SL,Hurwitz JL

更新日期：2013-02-05 00:00:00

abstract：:Infectious bronchitis virus (IBV) and Newcastle disease virus (NDV) are two poultry pathogens seriously affecting the poultry industry. Here, IBV S1 and the ectodomain of NDV F proteins were separately linked with the trans-membrane and carboxy-terminal domain of IBV S protein (STMCT), composing rS and rF; thus, a nov...

journal_title：Viruses

authors： Wu X,Zhai X,Lai Y,Zuo L,Zhang Y,Mei X,Xiang R,Kang Z,Zhou L,Wang H

更新日期：2019-03-13 00:00:00

abstract：:At the forefront of vector control efforts are strategies that leverage host-microbe associations to reduce vectorial capacity. The most promising of these efforts employs Wolbachia, a maternally transmitted endosymbiotic bacterium naturally found in 40% of insects. Wolbachia can spread through a population of insects...

journal_title：Viruses

authors： Lindsey ARI,Bhattacharya T,Newton ILG,Hardy RW

更新日期：2018-03-21 00:00:00

abstract：:Although there have been many epidemiological reports of the inter-country transmission of measles, systematic analysis of the global transmission dynamics of the measles virus (MV) is limited. In this study, we applied phylogeographic analysis to characterize the global transmission dynamics of the MV using large-sca...

journal_title：Viruses

authors： Furuse Y,Oshitani H

更新日期：2017-04-16 00:00:00

abstract：:Foodborne illnesses remain a major cause of hospitalization and death worldwide despite many advances in food sanitation techniques and pathogen surveillance. Traditional antimicrobial methods, such as pasteurization, high pressure processing, irradiation, and chemical disinfectants are capable of reducing microbial p...

journal_title：Viruses

authors： Moye ZD,Woolston J,Sulakvelidze A

更新日期：2018-04-19 00:00:00

abstract：:Influenza A virus (IAV) in swine, so-called swine influenza A virus (swIAV), causes respiratory illness in pigs around the globe. In Danish pig herds, a H1N2 subtype named H1N2dk is one of the main circulating swIAV. In this cohort study, the infection dynamic of swIAV was evaluated in a Danish pig herd by sampling an...

journal_title：Viruses

authors： Bhatta TR,Ryt-Hansen P,Nielsen JP,Larsen LE,Larsen I,Chamings A,Goecke NB,Alexandersen S

更新日期：2020-09-10 00:00:00

abstract：:The mouse mammary tumor virus (MMTV) Pr77Gag polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be formed. This process requires specific recognition and packaging of dimerized genomic RNA (gRNA) by Gag during virus assembly. Most of the previous work on retrovira...

journal_title：Viruses

authors： Chameettachal A,Pillai VN,Ali LM,Pitchai FNN,Ardah MT,Mustafa F,Marquet R,Rizvi TA

更新日期：2018-06-18 00:00:00

abstract：:SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated viral infection are important for studying immunity. Because SARS-CoV-2 is a biosafety-level-3 virus, one way to simplify such assays is ...

journal_title：Viruses

authors： Crawford KHD,Eguia R,Dingens AS,Loes AN,Malone KD,Wolf CR,Chu HY,Tortorici MA,Veesler D,Murphy M,Pettie D,King NP,Balazs AB,Bloom JD

更新日期：2020-05-06 00:00:00

abstract：:At the end of 2019, a new disease appeared and spread all over the world, the COVID-19, produced by the coronavirus SARS-CoV-2. As a consequence of this worldwide health crisis, the scientific community began to redirect their knowledge and resources to fight against it. Here we summarize the recent research on viruse...

journal_title：Viruses

authors： Fernandez-Garcia L,Pacios O,González-Bardanca M,Blasco L,Bleriot I,Ambroa A,López M,Bou G,Tomás M

更新日期：2020-10-16 00:00:00

abstract：:At present, the clinical detection method of human papillomavirus (HPV) is mainly based on the PCR method. However, this method can only be used to detect HPV DNA and HPV types, and cannot be used to accurately predict cervical cancer. HPV16 E7 is an oncoprotein selectively expressed in cervical cancers. In this study...

journal_title：Viruses

authors： Hu R,Dong Z,Zhang K,Pan G,Li C,Cui H

更新日期：2020-03-19 00:00:00

abstract：:The human OAS1 (hOAS1) gene produces multiple possible isoforms due to alternative splicing events and sequence variation among individuals, some of which affect splicing. The unique C-terminal sequences of the hOAS1 isoforms could differentially affect synthetase activity, protein stability, protein partner interacti...

journal_title：Viruses

authors： Di H,Elbahesh H,Brinton MA

更新日期：2020-01-29 00:00:00

abstract：:The human respiratory syncytial virus (hRSV) and human Metapneumovirus (hMPV) are two of the leading etiological agents of acute lower respiratory tract infections, which constitute the main cause of mortality in infants. However, there are currently approved vaccines for neither hRSV nor hMPV. Moreover, despite the s...

journal_title：Viruses

authors： Andrade CA,Pacheco GA,Gálvez NMS,Soto JA,Bueno SM,Kalergis AM

更新日期：2020-06-12 00:00:00

abstract：:The orthopoxviruses (OPV) comprise several emerging viruses with great importance to human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of bovine vaccinia (BV) in South America. Historically, VACV is the most comprehensively studied virus, however, its origin and natural hosts remai...

journal_title：Viruses

authors： Oliveira JS,Figueiredo PO,Costa GB,Assis FL,Drumond BP,da Fonseca FG,Nogueira ML,Kroon EG,Trindade GS

更新日期：2017-11-15 00:00:00

abstract：:Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems are key immune mechanisms helping prokaryotic species fend off RNA and DNA viruses. CRISPR/Cas9 has broad applications in basic research and biotechnology and has been widely used across eukaryotic species for genome...

journal_title：Viruses

authors： Aman R,Mahas A,Butt H,Aljedaani F,Mahfouz M

更新日期：2018-12-19 00:00:00

abstract：:While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. Among 1779 bat samples collected in China, diverse coronaviruses were detected in 32 samples from five different bat species by RT-PCR. Two novel alpha...

journal_title：Viruses

authors： Lau SKP,Wong ACP,Zhang L,Luk HKH,Kwok JSL,Ahmed SS,Cai JP,Zhao PSH,Teng JLL,Tsui SKW,Yuen KY,Woo PCY

更新日期：2019-05-07 00:00:00

abstract：:Since the emergence of NADC30-like porcine reproductive and respiratory syndrome virus (PRRSV) in China in 2013, PRRSVs have undergone rapid evolution. In this study, a novel variant of PRRSV strain (designated SCcd17) was successfully isolated from piglets with clinical signs in Sichuan Province in China in 2017, and...

journal_title：Viruses

authors： Zhou L,Kang R,Xie B,Tian Y,Wu X,Lv X,Yang X,Wang H

更新日期：2018-03-27 00:00:00

abstract：:During the last 25 years, swine vesicular disease (SVD) has occurred in Italy mostly sub-clinically. Therefore, regular testing of fecal samples from suspected holdings and high turnover premises was fundamental to identifying virus circulation and to achieve SVD eradication. In this study, we evaluated diagnostic per...

journal_title：Viruses

authors： Pezzoni G,Benedetti D,Bregoli A,Barbieri I,Foglia EA,Grazioli S,Brocchi E

更新日期：2020-11-20 00:00:00