当前位置： SCI文献检索 > Viruses-Basel期刊下所有文献 > Identification and characterization of porcine kobuvirus variant isolated from suckling piglet in Gansu province, China.

Identification and characterization of porcine kobuvirus variant isolated from suckling piglet in Gansu province, China.

Abstract：

:Kobuviruses comprise three species, the Aichivirus A, Aichivirus B, and Aichivirus C (porcine kobuvirus). Porcine kobuvirus is endemic to pig farms and is not restricted geographically but, rather, is distributed worldwide. The complete genomic sequences of four porcine kobuvirus strains isolated during a diarrhea outbreak in piglets in the Gansu province of China were determined. Two of these strains exhibited variations relative to the traditional strains. The potential 3C/3D cleavage sites of the variant strains were Q/C, which differed from the Q/S in the traditional porcine kobuvirus genome. A 90-nucleotide deletion in the 2B protein and a single nucleotide insertion in the 3'UTR were found in the variant strains. The VP1 regions of all four porcine kobuviruses in our study were highly variable (81%-86%). Ten common amino acid mutations were found specifically at certain positions within the VP1 region. Significant recombination sites were identified using SimPlot scans of whole genome sequences. Porcine kobuviruses were also detected in pig serum, indicating that the virus can escape the gastrointestinal tract and travel to the circulatory system. These findings suggest that mutations and recombination events may have contributed to the high level of genetic diversity of porcine kobuviruses and serve as a driving force in its evolution.

journal_name

Viruses

journal_title

Viruses

authors

Fan S,Sun H,Ying Y,Gao X,Wang Z,Yu Y,Li Y,Wang T,Yu Z,Yang S,Zhao Y,Qin C,Gao Y,Xia X

doi

10.3390/v5102548

subject

Has Abstract

pub_date

2013-10-18 00:00:00

pages

2548-60

issue

10

issn

1999-4915

pii

v5102548

journal_volume

5

pub_type

杂志文章

相关文献

Viruses-Basel文献大全
  • Transcriptomic Analysis of the Campylobacter jejuni Response to T4-Like Phage NCTC 12673 Infection.

    abstract：:Campylobacter jejuni is a frequent foodborne pathogen of humans. As C. jejuni infections commonly arise from contaminated poultry, phage treatments have been proposed to reduce the C. jejuni load on farms to prevent human infections. While a prior report documented the transcriptome of C. jejuni phages during the carr...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v10060332

    authors： Sacher JC,Flint A,Butcher J,Blasdel B,Reynolds HM,Lavigne R,Stintzi A,Szymanski CM

    更新日期：2018-06-16 00:00:00

  • Genetic Diversity of the Noncoding Control Region of the Novel Human Polyomaviruses.

    abstract：:The genomes of polyomaviruses are characterized by their tripartite organization with an early region, a late region and a noncoding control region (NCCR). The early region encodes proteins involved in replication and transcription of the viral genome, while expression of the late region generates the capsid proteins....

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v12121406

    authors： Moens U,Prezioso C,Pietropaolo V

    更新日期：2020-12-07 00:00:00

  • Bovine Lactoferrin Prevents Influenza A Virus Infection by Interfering with the Fusogenic Function of Viral Hemagglutinin.

    abstract：:Bovine lactoferrin (bLf) is an iron-binding glycoprotein folded in two symmetric globular lobes (N- and C-lobes) with potent antimicrobial and immunomodulatory activities. Recently, we have shown that bLf, and in particular its C-lobe, interacts with influenza A virus hemagglutinin and prevents infection by different ...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v11010051

    authors： Superti F,Agamennone M,Pietrantoni A,Ammendolia MG

    更新日期：2019-01-11 00:00:00

  • New Markers in Monitoring the Reactivation of Hepatitis B Virus Infection in Immunocompromised Hosts.

    abstract：:Hepatitis B virus (HBV) persistence is at the basis of HBV reactivation as a consequence of chemotherapy and immunosuppressive treatments. The identification of early viral replication indicators and markers of effective HBV immunological control would be useful in monitoring patients who are at risk of potential vira...

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v11090783

    authors： Svicher V,Salpini R,Malagnino V,Piermatteo L,Alkhatib M,Cerva C,Sarmati L

    更新日期：2019-08-25 00:00:00

  • Dendritic Cells in Innate and Adaptive Immune Responses against Influenza Virus.

    abstract：:Dendritic cells (DC) are major players in both innate and adaptive immune responses against influenza virus. These immune responses, as well as the important interface between the innate and adaptive systems, are orchestrated by specialized subsets of DC, including conventional steady-state DC, migratory DC and plasma...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v1031022

    authors： Summerfield A,McCullough KC

    更新日期：2009-12-01 00:00:00

  • Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus.

    abstract：:The Gammacoronavirus infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not replicate in cell culture, making the study of their basic virolo...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v12101102

    authors： Stevenson-Leggett P,Keep S,Bickerton E

    更新日期：2020-09-29 00:00:00

  • Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing.

    abstract：:The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. Intracellular expression of P triggers SOS-independent cellular filamenta...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v8060172

    authors： Hayes S,Wang W,Rajamanickam K,Chu A,Banerjee A,Hayes C

    更新日期：2016-06-22 00:00:00

  • Cell Lines for Honey Bee Virus Research.

    abstract：:With ongoing colony losses driven in part by the Varroa mite and the associated exacerbation of the virus load, there is an urgent need to protect honey bees (Apis mellifera) from fatal levels of virus infection and from the non-target effects of insecticides used in agricultural settings. A continuously replicating c...

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v12020236

    authors： Guo Y,Goodman CL,Stanley DW,Bonning BC

    更新日期：2020-02-20 00:00:00

  • Neutralizing Epitopes and Residues Mediating the Potential Antigenic Drift of the Hemagglutinin-Esterase Protein of Influenza C Virus.

    abstract：:We mapped the hemagglutinin-esterase (HE) antigenic epitopes of the influenza C virus on the three-dimensional (3D) structure of the HE glycoprotein using 246 escape mutants that were selected by a panel of nine anti-HE monoclonal antibodies (MAbs), including seven of the C/Ann Arbor/1/50 virus and two of the C/Yamaga...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v10080417

    authors： Matsuzaki Y,Sugawara K,Furuse Y,Shimotai Y,Hongo S,Mizuta K,Nishimura H

    更新日期：2018-08-09 00:00:00

  • Co-Circulation of Multiple Serotypes of Bluetongue Virus in Zambia.

    abstract：:Bluetongue (BT) is an arthropod-borne viral disease of ruminants with serious trade and socio-economic implications. Although the disease has been reported in a number of countries in sub-Saharan Africa, there is currently no information on circulating serotypes and disease distribution in Zambia. Following surveillan...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v12090963

    authors： Chambaro HM,Sasaki M,Simulundu E,Silwamba I,Sinkala Y,Gonzalez G,Squarre D,Fandamu P,Lubaba CH,Munyeme M,Maseko A,Chimvwele C,Mataa L,Mooya LE,Mukubesa AN,Harima H,Samui KL,Munang'andu HM,Simuunza M,Nalubamba KS,Q

    更新日期：2020-08-31 00:00:00

  • PCR Detection and Phylogenetic Analysis of Megalocytivirus Isolates in Farmed Giant Sea Perch Lates calcarifer in Southern Taiwan.

    abstract：:The Megalocytivirus genus includes three genotypes, red sea bream iridovirus (RSIV), infectious spleen and kidney necrosis virus (ISKNV), and turbot reddish body iridovirus (TRBIV), and has caused mass mortalities in various marine and freshwater fish species in East and Southeast Asia. Of the three genotypes, TRBIV-l...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v12060681

    authors： Tsai JM,Huang SL,Yang CD

    更新日期：2020-06-24 00:00:00

  • Evolution of the Piscine orthoreovirus Genome Linked to Emergence of Heart and Skeletal Muscle Inflammation in Farmed Atlantic Salmon (Salmo salar).

    abstract：:Heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar) was first diagnosed in Norway in 1999. The disease is caused by Piscine orthoreovirus-1 (PRV-1). The virus is prevalent in farmed Atlantic salmon, but not always associated with disease. Phylogeny and sequence analyses of 31 PRV-1 ge...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v11050465

    authors： Dhamotharan K,Tengs T,Wessel Ø,Braaen S,Nyman IB,Hansen EF,Christiansen DH,Dahle MK,Rimstad E,Markussen T

    更新日期：2019-05-22 00:00:00

  • A Lineage of Begomoviruses Encode Rep and AC4 Proteins of Enigmatic Ancestry: Hints on the Evolution of Geminiviruses in the New World.

    abstract：:The begomoviruses (BGVs) are plant pathogens that evolved in the Old World during the Cretaceous and arrived to the New World (NW) in the Cenozoic era. A subgroup of NW BGVs, the "Squash leaf curl virus (SLCV) lineage" (S-Lin), includes viruses with unique characteristics. To get clues on the evolutionary origin of th...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v11070644

    authors： Torres-Herrera SI,Romero-Osorio A,Moreno-Valenzuela O,Pastor-Palacios G,Cardenas-Conejo Y,Ramírez-Prado JH,Riego-Ruiz L,Minero-García Y,Ambriz-Granados S,Argüello-Astorga GR

    更新日期：2019-07-13 00:00:00

  • Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation.

    abstract：:The most highly expressed protein during the productive phase of the human papillomavirus (HPV) life cycle is E1^E4. Its full role during infection remains to be established. HPV E1^E4 is expressed during both the early and late stages of the virus life cycle and contributes to viral genome amplification. In an attemp...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v9120385

    authors： Biryukov J,Myers JC,McLaughlin-Drubin ME,Griffin HM,Milici J,Doorbar J,Meyers C

    更新日期：2017-12-19 00:00:00

  • Genetic Analysis of the Full-Length gag Gene from the Earliest Korean Subclade B of HIV-1: An Outbreak among Korean Hemophiliacs.

    abstract：:We determined the earliest full-length HIV-1 gag gene sequences in 110 patients with HIV-1, including 20 hemophiliacs (HPs) and 90 local controls (LCs). The gag gene from stored sera was amplified using RT-PCR, and was subjected to direct sequencing. Phylogenetic analysis indicated that 94 and 16 sequences belonged to...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v11060545

    authors： Cho YK,Kim JE,Foley BT

    更新日期：2019-06-11 00:00:00

  • Vesicular Nucleo-Cytoplasmic Transport-Herpesviruses as Pioneers in Cell Biology.

    abstract：:Herpesviruses use a vesicle-mediated transfer of intranuclearly assembled nucleocapsids through the nuclear envelope (NE) for final maturation in the cytoplasm. The molecular basis for this novel vesicular nucleo-cytoplasmic transport is beginning to be elucidated in detail. The heterodimeric viral nuclear egress comp...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v8100266

    authors： Mettenleiter TC

    更新日期：2016-09-27 00:00:00

  • An Update of the Virion Proteome of Kaposi Sarcoma-Associated Herpesvirus.

    abstract：:The virion proteins of Kaposi sarcoma-associated herpesvirus (KSHV) were initially characterized in 2005 in two separate studies that combined the detection of 24 viral proteins and a few cellular components via LC-MS/MS or MALDI-TOF. Despite considerable advances in the sensitivity and specificity of mass spectrometr...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v12121382

    authors： Nabiee R,Syed B,Ramirez Castano J,Lalani R,Totonchy JE

    更新日期：2020-12-02 00:00:00

  • Challenges in mucosal HIV vaccine development: lessons from non-human primate models.

    abstract：:An efficacious HIV vaccine is urgently needed to curb the AIDS pandemic. The modest protection elicited in the phase III clinical vaccine trial in Thailand provided hope that this goal might be achieved. However, new approaches are necessary for further advances. As HIV is transmitted primarily across mucosal surfaces...

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v6083129

    authors： Tuero I,Robert-Guroff M

    更新日期：2014-08-15 00:00:00

  • Nipah Virus: Past Outbreaks and Future Containment.

    abstract：:Viral outbreaks of varying frequencies and severities have caused panic and havoc across the globe throughout history. Influenza, small pox, measles, and yellow fever reverberated for centuries, causing huge burden for economies. The twenty-first century witnessed the most pathogenic and contagious virus outbreaks of ...

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v12040465

    authors： Soman Pillai V,Krishna G,Valiya Veettil M

    更新日期：2020-04-20 00:00:00

  • RNase L Is Involved in Liposaccharide-Induced Lung Inflammation.

    abstract：:RNase L mediates interferon (IFN) function during viral infection and cell proliferation. Furthermore, the role of RNase L in the regulation of gene expression, cell apoptosis, autophagy, and innate immunity has been well established in the last decade. Tissue distribution reveals that RNase L is highly expressed in t...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v12010073

    authors： Wei R,Chen G,Algehainy N,Zeng C,Liu C,Liu H,Liu W,Stacey D,Zhou A

    更新日期：2020-01-07 00:00:00

  • Biochemical and Functional Characterization of Mouse Mammary Tumor Virus Full-Length Pr77Gag Expressed in Prokaryotic and Eukaryotic Cells.

    abstract：:The mouse mammary tumor virus (MMTV) Pr77Gag polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be formed. This process requires specific recognition and packaging of dimerized genomic RNA (gRNA) by Gag during virus assembly. Most of the previous work on retrovira...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v10060334

    authors： Chameettachal A,Pillai VN,Ali LM,Pitchai FNN,Ardah MT,Mustafa F,Marquet R,Rizvi TA

    更新日期：2018-06-18 00:00:00

  • HIV-1 Virological Synapse: Live Imaging of Transmission.

    abstract：:A relatively new aspect of HIV-1 biology is the ability of the virus to infect cells by direct cellular contacts across a specialized structure, the virological synapse. This process was recently described through live cell imaging. Together with the accumulated knowledge on cellular and molecular structures involved ...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v2081666

    authors： Feldmann J,Schwartz O

    更新日期：2010-08-01 00:00:00

  • Following in the Footsteps of the Chikungunya Virus in Brazil: The First Autochthonous Cases in Amapá in 2014 and Its Emergence in Rio de Janeiro during 2016.

    abstract：:Currently, Brazil lives a triple arboviruses epidemic (DENV, ZIKV and CHIKV) making the differential diagnosis difficult for health professionals. Here, we aimed to investigate chikungunya cases and the possible occurrence of co-infections during the epidemic in Amapá (AP) that started in 2014 when the first autochtho...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v10110623

    authors： de Souza TMA,Ribeiro ED,Corrêa VCE,Damasco PV,Santos CC,de Bruycker-Nogueira F,Chouin-Carneiro T,Faria NRDC,Nunes PCG,Heringer M,Lima MDRQ,Badolato-Corrêa J,Cipitelli MDC,Azeredo EL,Nogueira RMR,Dos Santos FB

    更新日期：2018-11-12 00:00:00

  • HIV-1 replication and the cellular eukaryotic translation apparatus.

    abstract：:Eukaryotic translation is a complex process composed of three main steps: initiation, elongation, and termination. During infections by RNA- and DNA-viruses, the eukaryotic translation machinery is used to assure optimal viral protein synthesis. Human immunodeficiency virus type I (HIV-1) uses several non-canonical pa...

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v7010199

    authors： Guerrero S,Batisse J,Libre C,Bernacchi S,Marquet R,Paillart JC

    更新日期：2015-01-19 00:00:00

  • Time-Course Microarray Analysis Reveals Differences between Transcriptional Changes in Tomato Leaves Triggered by Mild and Severe Variants of Potato Spindle Tuber Viroid.

    abstract：:Viroids are small non-capsidated non-coding RNA replicons that utilize host factors for efficient propagation and spread through the entire plant. They can incite specific disease symptoms in susceptible plants. To better understand viroid-plant interactions, we employed microarray analysis to observe the changes of g...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v10050257

    authors： Więsyk A,Iwanicka-Nowicka R,Fogtman A,Zagórski-Ostoja W,Góra-Sochacka A

    更新日期：2018-05-15 00:00:00

  • Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants? Viruses 2012, 4, 1711-1730.

    abstract：:In the original manuscript, the text in figure 1 is illegible. Furthermore, there is an unnecessary carriage return (page 1716, ~line 18) "crystallographic ... methods". ...

    journal_title：Viruses

    pub_type： 杂志文章,已发布勘误

    doi：10.3390/v4102014

    authors： Mwimanzi P,Markle TJ,Ueno T,Brockman MA

    更新日期：2012-10-05 00:00:00

  • Protective Immunity Induced by DNA Vaccination against Ranavirus Infection in Chinese Giant Salamander Andrias davidianus.

    abstract：:Andrias davidianus ranavirus (ADRV) is an emerging viral pathogen that causes severe systemic hemorrhagic disease in Chinese giant salamanders. There is an urgent need for developing an effective vaccine against this fatal disease. In this study, DNA vaccines containing the ADRV 2L gene (pcDNA-2L) and the 58L gene (pc...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v10020052

    authors： Chen ZY,Li T,Gao XC,Wang CF,Zhang QY

    更新日期：2018-01-24 00:00:00

  • Successive Passage In Vitro Led to Lower Virulence and Higher Titer of A Variant Porcine Epidemic Diarrhea Virus.

    abstract：:A highly virulent porcine epidemic diarrhea virus (PEDV) appeared in China and spread rapidly to neighbor countries, which have led to great economic losses to the pig industry. In the present study, we isolated a PEDV using Vero cells and serially propagated 100 passages. PEDV SDSX16 was characterized in vitro and in...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v12040391

    authors： Zhao P,Wang S,Chen Z,Yu J,Tang R,Qiu W,Zhao L,Liu Y,Guo X,He H,Xu G,Li J,Wu J

    更新日期：2020-04-01 00:00:00

  • Role of innate immunity against human papillomavirus (HPV) infections and effect of adjuvants in promoting specific immune response.

    abstract：:During the early stages of human papillomavirus (HPV) infections, the innate immune system creates a pro-inflammatory microenvironment by recruiting innate immune cells to eliminate the infected cells, initiating an effective acquired immune response. However, HPV exhibits a wide range of strategies for evading immune...

    journal_title：Viruses

    pub_type： 杂志文章,评审

    doi：10.3390/v5112624

    authors： Amador-Molina A,Hernández-Valencia JF,Lamoyi E,Contreras-Paredes A,Lizano M

    更新日期：2013-10-28 00:00:00

  • Antiviral Hammerhead Ribozymes Are Effective for Developing Transgenic Suppression of Chikungunya Virus in Aedes aegypti Mosquitoes.

    abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

    journal_title：Viruses

    pub_type： 杂志文章

    doi：10.3390/v8060163

    authors： Mishra P,Furey C,Balaraman V,Fraser MJ

    更新日期：2016-06-10 00:00:00