Abstract:
:A relatively new aspect of HIV-1 biology is the ability of the virus to infect cells by direct cellular contacts across a specialized structure, the virological synapse. This process was recently described through live cell imaging. Together with the accumulated knowledge on cellular and molecular structures involved in cell-to-cell transmission of HIV-1, the visualization of the virological synapse in video-microscopy has brought exciting new hypotheses on its underlying mechanisms. This review will recapitulate current knowledge with a particular emphasis on the questions live microscopy has raised.
journal_name
Virusesjournal_title
Virusesauthors
Feldmann J,Schwartz Odoi
10.3390/v2081666subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1666-80issue
8issn
1999-4915pii
viruses-02-01666journal_volume
2pub_type
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