Porcine Dendritic Cells and Viruses: An Update.

abstract：:The Vibrio cholerae biotype "El Tor" is responsible for all of the current epidemic and endemic cholera outbreaks worldwide. These outbreaks are clonal, and it is hypothesized that they originate from the coastal areas near the Bay of Bengal, where the lytic bacteriophage ICP1 (International Centre for Diarrhoeal Dise...

journal_title：Viruses

authors： Angermeyer A,Das MM,Singh DV,Seed KD

更新日期：2018-06-01 00:00:00

abstract：:Hepatitis C Virus (HCV) remains an important public health threat with approximately 170 million carriers worldwide who are at risk of developing hepatitis C-associated end-stage liver diseases. Despite improvement of HCV treatment using the novel direct-acting antivirals (DAAs) targeting viral replication, there is a...

journal_title：Viruses

authors： Hung TC,Jassey A,Lin CJ,Liu CH,Lin CC,Yen MH,Lin LT

更新日期：2018-11-27 00:00:00

abstract：:Gammaherpesviruses like Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) subvert the ubiquitin proteasome system for their own benefit in order to facilitate viral gene expression and replication. In particular, viral tegument proteins that share sequence homology to the formylglycineamide r...

journal_title：Viruses

authors： Full F,Hahn AS,Großkopf AK,Ensser A

更新日期：2017-10-21 00:00:00

abstract：:Metagenomics studies have accelerated the discovery of novel or divergent viruses of the honey bee. However, most of these studies predominantly focused on RNA viruses, and many suffer from the relatively low abundance of viral nucleic acids in the samples (i.e., compared to that of the host). Here, we explored the vi...

journal_title：Viruses

authors： Gebremedhn H,Deboutte W,Schoonvaere K,Demaeght P,De Smet L,Amssalu B,Matthijnssens J,de Graaf DC

更新日期：2020-10-27 00:00:00

abstract：:The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of severe hemorrhagic fever outbreaks in central Africa, with case fata...

journal_title：Viruses

authors： Cárdenas WB

更新日期：2010-01-01 00:00:00

abstract：:It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and c...

journal_title：Viruses

authors： Grove J

更新日期：2014-03-19 00:00:00

abstract：:Viruses protect their genomes by enclosing them into protein capsids that sometimes contain lipid bilayers that either reside above or below the protein layer. Controlled dissociation of virions provides important information on virion composition, interactions, and stoichiometry of virion components, as well as their...

journal_title：Viruses

authors： Eskelin K,Poranen MM

更新日期：2018-10-23 00:00:00

abstract：:Protoparvoviruses are simple single-stranded DNA viruses that infect many animal species. The protoparvovirus minute virus of mice (MVM) infects murine and transformed human cells provoking a sustained DNA damage response (DDR). This DDR is dependent on signaling by the ATM kinase and leads to a prolonged pre-mitotic ...

journal_title：Viruses

authors： Majumder K,Etingov I,Pintel DJ

更新日期：2017-10-31 00:00:00

abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

journal_title：Viruses

authors： Mishra P,Furey C,Balaraman V,Fraser MJ

更新日期：2016-06-10 00:00:00

abstract：:We are currently facing a pandemic of COVID-19, caused by a spillover from an animal-originating coronavirus to humans occurring in the Wuhan region of China in December 2019. From China, the virus has spread to 188 countries and regions worldwide, reaching the Sahel region on March 2, 2020. Since whole genome sequenc...

journal_title：Viruses

authors： Kouriba B,Dürr A,Rehn A,Sangaré AK,Traoré BY,Bestehorn-Willmann MS,Ouedraogo J,Heitzer A,Sogodogo E,Maiga A,Walter MC,Zimmermann F,Wölfel R,Antwerpen MH

更新日期：2020-11-02 00:00:00

abstract：:Diagnostic electron microscopy for infectious diseases has the advantage that "everything" in the specimen can be observed, without a priori knowledge of the likely identity of the microorganisms present in the sample. The classical specimen preparation method used employs a droplet of sample, which allows particles t...

journal_title：Viruses

authors： Beniac DR,Siemens CG,Wright CJ,Booth TF

更新日期：2014-09-19 00:00:00

abstract：:Historically, mice and guinea pigs have been the rodent models of choice for therapeutic and prophylactic countermeasure testing against Ebola virus disease (EVD). Recently, hamsters have emerged as a novel animal model for the in vivo study of EVD. In this review, we discuss the history of the hamster as a research l...

journal_title：Viruses

authors： Wahl-Jensen V,Bollinger L,Safronetz D,de Kok-Mercado F,Scott DP,Ebihara H

更新日期：2012-12-14 00:00:00

abstract：:The hepatitis C virus (HCV), a hepatotropic plus-strand RNA virus of the family Flaviviridae, encodes a set of 10 viral proteins. These viral factors act in concert with host proteins to mediate virus entry, and to coordinate RNA replication and virus production. Recent evidence has highlighted the complexity of HCV a...

journal_title：Viruses

authors： Steinmann E,Pietschmann T

更新日期：2010-09-01 00:00:00

abstract：:Between January 2012 and March 2012, the infection rates of porcine epidemic diarrhea virus (PEDV) increased substantially in vaccinated swine herds in many porcine farms in Gansu Province, China. The spike (S) glycoprotein is an important determinant for PEDV biological properties. To determine the distribution profi...

journal_title：Viruses

authors： Tian Y,Yu Z,Cheng K,Liu Y,Huang J,Xin Y,Li Y,Fan S,Wang T,Huang G,Feng N,Yang Z,Yang S,Gao Y,Xia X

更新日期：2013-08-15 00:00:00

abstract：:The use of integrase inhibitors (INI) is increasing in antiretroviral therapies (ART) and INI are not all equal regarding genetic barrier to resistance. The aim of this manuscript was to review main in vivo and in vitro knowledge about two particular integrase resistance-associated mutations: R263K and E157Q. The R263...

journal_title：Viruses

authors： Charpentier C,Descamps D

更新日期：2018-01-18 00:00:00

abstract：:RNA secondary structures play diverse roles in positive-sense (+) RNA virus infections, but those located with the replication protein coding sequence can be difficult to investigate. Structures that regulate the translation of replication proteins pose particular challenges, as their potential involvement in post-tra...

journal_title：Viruses

authors： Sun R,Zhang S,Zheng L,Qu F

更新日期：2020-03-22 00:00:00

abstract：:Enteric viral co-infections, infections involving more than one virus, have been reported for a diverse group of etiological agents, including rotavirus, norovirus, astrovirus, adenovirus, and enteroviruses. These pathogens are causative agents for acute gastroenteritis and diarrheal disease in immunocompetent and imm...

journal_title：Viruses

authors： Makimaa H,Ingle H,Baldridge MT

更新日期：2020-08-18 00:00:00

abstract：:We show that focused ion beam/scanning electron microscopy (FIB/SEM) tomography is an excellent method to analyze the three-dimensional structure of a fibroblast nucleus infected with human cytomegalovirus (HCMV). We found that the previously described infoldings of the inner nuclear membrane, which are unique among i...

journal_title：Viruses

authors： Villinger C,Neusser G,Kranz C,Walther P,Mertens T

更新日期：2015-11-04 00:00:00

abstract：:Andrias davidianus ranavirus (ADRV) is an emerging viral pathogen that causes severe systemic hemorrhagic disease in Chinese giant salamanders. There is an urgent need for developing an effective vaccine against this fatal disease. In this study, DNA vaccines containing the ADRV 2L gene (pcDNA-2L) and the 58L gene (pc...

journal_title：Viruses

authors： Chen ZY,Li T,Gao XC,Wang CF,Zhang QY

更新日期：2018-01-24 00:00:00

abstract：:Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed. Spontaneous resolution of infection is associated with effective host adaptive immunity t...

journal_title：Viruses

authors： Tarr AW,Urbanowicz RA,Ball JK

更新日期：2012-01-01 00:00:00

abstract：:Two sister orders of the brown macroalgae (class Phaeophyceae), the morphologically complex Laminariales (commonly referred to as kelp) and the morphologically simple Ectocarpales are natural hosts for the dsDNA phaeoviruses (family Phycodnaviridae) that persist as proviruses in the genomes of their hosts. We have pre...

journal_title：Viruses

authors： McKeown DA,Schroeder JL,Stevens K,Peters AF,Sáez CA,Park J,Rothman MD,Bolton JJ,Brown MT,Schroeder DC

更新日期：2018-08-05 00:00:00

abstract：:Bluetongue (BT) is an arthropod-borne viral disease of ruminants with serious trade and socio-economic implications. Although the disease has been reported in a number of countries in sub-Saharan Africa, there is currently no information on circulating serotypes and disease distribution in Zambia. Following surveillan...

journal_title：Viruses

authors： Chambaro HM,Sasaki M,Simulundu E,Silwamba I,Sinkala Y,Gonzalez G,Squarre D,Fandamu P,Lubaba CH,Munyeme M,Maseko A,Chimvwele C,Mataa L,Mooya LE,Mukubesa AN,Harima H,Samui KL,Munang'andu HM,Simuunza M,Nalubamba KS,Q

更新日期：2020-08-31 00:00:00

abstract：:HIV continues to spread among vulnerable heterosexual (HET), Men-having-Sex with Men (MSM) and intravenous drug user (IDU) populations, influenced by a complex array of biological, behavioral and societal factors. Phylogenetics analyses of large sequence datasets from national drug resistance testing programs reveal t...

journal_title：Viruses

authors： Brenner BG,Ibanescu RI,Hardy I,Roger M

更新日期：2017-12-28 00:00:00

abstract：:Parrot bornaviruses (PaBVs) are the causative agents of proventricular dilatation disease (PDD), a chronic and often fatal neurologic disorder in Psittaciformes. The disease is widely distributed in private parrot collections and threatens breeding populations of endangered species. Thus, immunoprophylaxis strategies ...

journal_title：Viruses

authors： Rall I,Amann R,Malberg S,Herden C,Rubbenstroth D

更新日期：2019-12-06 00:00:00

abstract：:It has been demonstrated that MEK1, one of the two MEK isoforms in Raf-MEK-ERK1/2 pathway, is essential for successful EV71 propagation. However, the distinct function of ERK1 and ERK2 isoforms, the downstream kinases of MEKs, remains unclear in EV71 replication. In this study, specific ERK siRNAs and selective inhibi...

journal_title：Viruses

authors： Zhu M,Duan H,Gao M,Zhang H,Peng Y

更新日期：2015-03-20 00:00:00

abstract：:Small Ruminant Lentiviruses (SRLVs) are widespread in many countries and cause economically relevant, slow, and persistent diseases in sheep and goats. Monitoring the genetic diversity of SRLVs is useful to improve the diagnostic tools used in the eradication programs. In this study, SRLVs detected in Spanish Assaf sh...

journal_title：Viruses

authors： Gayo E,Cuteri V,Polledo L,Rossi G,García Marín JF,Preziuso S

更新日期：2018-06-09 00:00:00

abstract：:Victoria and Yamagata lineages of influenza B viruses are globally circulating in seasonal epidemics. Madin-Darby canine kidney (MDCK) cells are permissive for viral isolation and vaccine manufacture. Nevertheless, the interplay between influenza B viruses and host microRNAs has not been investigated in this cell line...

journal_title：Viruses

authors： Saengchoowong S,Khongnomnan K,Poomipak W,Praianantathavorn K,Poovorawan Y,Zhang Q,Payungporn S

更新日期：2019-10-25 00:00:00

abstract：:Herpesviruses use a vesicle-mediated transfer of intranuclearly assembled nucleocapsids through the nuclear envelope (NE) for final maturation in the cytoplasm. The molecular basis for this novel vesicular nucleo-cytoplasmic transport is beginning to be elucidated in detail. The heterodimeric viral nuclear egress comp...

journal_title：Viruses

authors： Mettenleiter TC

更新日期：2016-09-27 00:00:00

abstract：:Under physiological conditions, the function of astrocytes in providing brain metabolic support is compromised under pathophysiological conditions caused by human immunodeficiency virus (HIV) and opioids. Herein, we examined the role of autophagy, a lysosomal degradation pathway important for cellular homeostasis and ...

journal_title：Viruses

authors： Rodriguez M,Lapierre J,Ojha CR,Estrada-Bueno H,Dever SM,Gewirtz DA,Kashanchi F,El-Hage N

更新日期：2017-07-28 00:00:00

abstract：UNLABELLED:Cytomegalovirus (CMV) is a prevalent pathogen in the immunocompromised host and invasive pneumonia is a feared complication of the virus in this population. In this pediatric case series we characterized CMV lung infection in 15 non-HIV infected children (median age 3 years; IQR 0.2-4.9 years), using current...

journal_title：Viruses

authors： Restrepo-Gualteros SM,Jaramillo-Barberi LE,Gonzalez-Santos M,Rodriguez-Martinez CE,Perez GF,Gutierrez MJ,Nino G

更新日期：2014-05-07 00:00:00