Resistance to HIV Integrase Inhibitors: About R263K and E157Q Mutations.

abstract：:Dengue, chikungunya and Zika viruses share similar disease features, rendering them difficult to distinguish clinically. Incapacitating arthralgia/arthritis is a specific manifestation associated with chikungunya virus infection. However, the profile of arthralgia/arthritis in Zika virus (ZIKV) cases has not been well...

journal_title：Viruses

authors： Wimalasiri-Yapa BMCR,Yapa HE,Huang X,Hafner LM,Kenna TJ,Frentiu FD

更新日期：2020-10-07 00:00:00

abstract：:Commentary on Pais-Correia, A.M.; Sachse, M.; Guadagnini, S.; Robbiati, V.; Lasserre, R.; Gessain, A.; Gout, O.; Alcover, A.; Thoulouze, M.I. Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses. Nat. Med.2010, 16, 83-89. ...

journal_title：Viruses

authors： Jin J,Sherer N,Mothes W

更新日期：2010-02-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is a major cause of pediatric infection and also causes disease in the elderly and those with underlying respiratory problems. There is no vaccine for HRSV and anti-viral therapeutics are not broadly applicable. To investigate the effect of HRSV biology in children, nasopharyng...

journal_title：Viruses

authors： Aljabr W,Armstrong S,Rickett NY,Pollakis G,Touzelet O,Cloutman-Green E,Matthews DA,Hiscox JA

更新日期：2019-10-10 00:00:00

abstract：:Filovirus serological diagnosis and epidemiological investigations are hampered due to the unavailability of validated immunoassays. Diagnostic performance of three indirect enzyme-linked immunosorbent assays (I-ELISA) was evaluated for the detection of IgG antibody to Ebola virus (EBOV) in human sera. One I-ELISA was...

journal_title：Viruses

authors： Paweska JT,Moolla N,Storm N,Msimang V,Conteh O,Weyer J,Vuren PJV

更新日期：2019-07-24 00:00:00

abstract：:In the last 20 years, molecular ecology approaches have proven to be extremely useful to identify and assess factors associated with viral emerging diseases, particularly in economically and socially important tropical crops such as maize (maize streak disease) and cassava (cassava mosaic disease). Molecular ecology a...

journal_title：Viruses

authors： Péréfarres F,Thierry M,Becker N,Lefeuvre P,Reynaud B,Delatte H,Lett JM

更新日期：2012-12-12 00:00:00

abstract：:Viral lysis is a main mortality factor for bacteria in deep-sea sediments, leading to changing microbial community structures and the release of cellular components to the environment. Nature and fate of these compounds and the role of viruses for microbial diversity is largely unknown. We investigated the effect of v...

journal_title：Viruses

authors： Heinrichs ME,Tebbe DA,Wemheuer B,Niggemann J,Engelen B

更新日期：2020-08-22 00:00:00

abstract：UNLABELLED:Cytomegalovirus (CMV) is a prevalent pathogen in the immunocompromised host and invasive pneumonia is a feared complication of the virus in this population. In this pediatric case series we characterized CMV lung infection in 15 non-HIV infected children (median age 3 years; IQR 0.2-4.9 years), using current...

journal_title：Viruses

authors： Restrepo-Gualteros SM,Jaramillo-Barberi LE,Gonzalez-Santos M,Rodriguez-Martinez CE,Perez GF,Gutierrez MJ,Nino G

更新日期：2014-05-07 00:00:00

abstract：:Progression of HIV infection is variable among individuals, and definition disease progression biomarkers is still needed. Here, we aimed to categorize the predictive potential of several variables using feature selection methods and decision trees. A total of seventy-five treatment-naïve subjects were enrolled during...

journal_title：Viruses

authors： Turk G,Ghiglione Y,Hormanstorfer M,Laufer N,Coloccini R,Salido J,Trifone C,Ruiz MJ,Falivene J,Holgado MP,Caruso MP,Figueroa MI,Salomón H,Giavedoni LD,Pando MLÁ,Gherardi MM,Rabinovich RD,Pury PA,Sued O

更新日期：2018-01-13 00:00:00

abstract：:Rapid and sensitive detection of prions is important in managing prion diseases. The real-time quaking-induced conversion (RT-QuIC) assay for prion seeding activity has been applied to many prion diseases and provides for specific antemortem diagnostic testing. We evaluated RT-QuIC's long-term consistency and varied m...

journal_title：Viruses

authors： Orrú CD,Hughson AG,Groveman BR,Campbell KJ,Anson KJ,Manca M,Kraus A,Caughey B

更新日期：2016-05-23 00:00:00

abstract：:Influenza A viruses (IAVs) are highly contagious pathogens infecting human and numerous animals. The viruses cause millions of infection cases and thousands of deaths every year, thus making IAVs a continual threat to global health. Upon IAV infection, host innate immune system is triggered and activated to restrict v...

journal_title：Viruses

authors： Zhang Y,Xu Z,Cao Y

更新日期：2020-03-29 00:00:00

abstract：:The Gammacoronavirus infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not replicate in cell culture, making the study of their basic virolo...

journal_title：Viruses

authors： Stevenson-Leggett P,Keep S,Bickerton E

更新日期：2020-09-29 00:00:00

abstract：:We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of exosomes, i.e., nanovesicles spontaneously released by all cell types. We engineered the upload of huge amounts of protein antigens upon fusion with an anchoring pro...

journal_title：Viruses

authors： Di Bonito P,Ridolfi B,Columba-Cabezas S,Giovannelli A,Chiozzini C,Manfredi F,Anticoli S,Arenaccio C,Federico M

更新日期：2015-03-09 00:00:00

abstract：:Human influenza A(H2N2) viruses emerged in 1957 and were replaced by A(H3N2) viruses in 1968. The antigenicity of human H2N2 viruses has been tested by using ferret antisera or mouse and human monoclonal antibodies. Here, we examined the antigenicity of human H2N2 viruses by using human plasma samples obtained from 50...

journal_title：Viruses

authors： Matsuzawa Y,Iwatsuki-Horimoto K,Nishimoto Y,Abe Y,Fukuyama S,Hamabata T,Okuda M,Go Y,Watanabe T,Imai M,Arai Y,Fouchier RAM,Yamayoshi S,Kawaoka Y

更新日期：2019-10-23 00:00:00

abstract：:Potato virus Y (PVY) is the most economically important virus infecting cultivated potato (Solanum tuberosum L.). Accurate diagnosis is crucial to regulate the trade of tubers and for the sanitary selection of plant material for propagation. However, high genetic diversity of PVY represents a challenge for the detecti...

journal_title：Viruses

authors： Della Bartola M,Byrne S,Mullins E

更新日期：2020-04-23 00:00:00

abstract：:Hepatitis delta virus (HDV) is currently only found in humans and is a satellite virus that depends on hepatitis B virus (HBV) envelope proteins for assembly, release, and entry. Using meta-transcriptomics, we identified the genome of a novel HDV-like agent in ducks. Sequence analysis revealed secondary structures tha...

journal_title：Viruses

authors： Wille M,Netter HJ,Littlejohn M,Yuen L,Shi M,Eden JS,Klaassen M,Holmes EC,Hurt AC

更新日期：2018-12-17 00:00:00

abstract：:Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, nov...

journal_title：Viruses

authors： Pérot P,Lecuit M,Eloit M

更新日期：2017-01-12 00:00:00

abstract：:Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral (PRRSV) disease in pigs characterized by poor reproductive health, increased mortality, and reductions in growth rates. PRRSV is known to implement immuno-antagonistic mechanisms to evade detection and mute host responses to infection. To bette...

journal_title：Viruses

authors： Hicks JA,Yoo D,Liu HC

更新日期：2020-11-12 00:00:00

abstract：:Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer than 5% of HBV-infected adults (but up to 90% of HBV-infected infants and children) develop chronic HBV infection as indicated by contin...

journal_title：Viruses

authors： Megahed FAK,Zhou X,Sun P

更新日期：2020-03-05 00:00:00

abstract：:We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection p...

journal_title：Viruses

authors： Andreo V,Neteler M,Rocchini D,Provensal C,Levis S,Porcasi X,Rizzoli A,Lanfri M,Scavuzzo M,Pini N,Enria D,Polop J

更新日期：2014-01-14 00:00:00

abstract：:Porcine circovirus 3 (PCV3) has been identified as a putative swine pathogen with a subset of infections resulting in stillborn and mummified fetuses, encephalitis and myocarditis in perinatal, and periarteritis in growing pigs. Three PCV3 isolates were isolated from weak-born piglets or elevated stillborn and mummifi...

journal_title：Viruses

authors： Mora-Díaz J,Piñeyro P,Shen H,Schwartz K,Vannucci F,Li G,Arruda B,Giménez-Lirola L

更新日期：2020-02-16 00:00:00

abstract：:Astroviruses (AstVs) cause disease in a wide variety of species. Porcine AstVs are highly genetically diverse and conventionally assigned to five genetic lineages (PoAstV1-5). Due to the increasing evidence that porcine astrovirus type 3 (PoAstV3) is a cause of encephalomyelitis in swine and to elucidate important eco...

journal_title：Viruses

authors： Rawal G,Ferreyra FM,Macedo NR,Bradner LK,Harmon KM,Allison G,Linhares DCL,Arruda BL

更新日期：2020-09-07 00:00:00

abstract：:Factors controlling the community composition of marine heterotrophic prokaryotes include organic-C, mineral nutrients, predation, and viral lysis. Two mesocosm experiments, performed at an Arctic location and bottom-up manipulated with organic-C, had very different results in community composition for both prokaryote...

journal_title：Viruses

authors： Sandaa RA,Pree B,Larsen A,Våge S,Töpper B,Töpper JP,Thyrhaug R,Thingstad TF

更新日期：2017-08-23 00:00:00

abstract：:The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS)...

journal_title：Viruses

authors： Jin Y,Yang H,Ji W,Wu W,Chen S,Zhang W,Duan G

更新日期：2020-03-27 00:00:00

abstract：:Small ruminant lentiviruses include members that infect sheep (ovine lentivirus [OvLV]; also known as ovine progressive pneumonia virus/maedi-visna virus) and goats (caprine arthritis encephalitis virus [CAEV]). Breed differences in seroprevalence and proviral concentration of OvLV had suggested a strong genetic compo...

journal_title：Viruses

authors： White SN,Knowles DP

更新日期：2013-06-14 00:00:00

abstract：:Koalas (Phascolarctos cinereus) are native Australian marsupials whose populations are in decline from a range of threats. Infectious diseases caused by the bacterium Chlamydia pecorum and other pathogens are of particular concern. We analysed 26 poly-A selected RNA-sequencing libraries from a data set designed to stu...

journal_title：Viruses

authors： Harvey E,Madden D,Polkinghorne A,Holmes EC

更新日期：2019-03-02 00:00:00

abstract：:Environmental genomics can describe all forms of organisms--cellular and viral--present in a community. The analysis of such eco-systems biology data relies heavily on reference databases, e.g., taxonomy or gene function databases. Reference databases of symbiosis sensu lato, although essential for the analysis of org...

journal_title：Viruses

authors： Mihara T,Nishimura Y,Shimizu Y,Nishiyama H,Yoshikawa G,Uehara H,Hingamp P,Goto S,Ogata H

更新日期：2016-03-01 00:00:00

abstract：:Human parechovirus (HPeV), particularly type 3 (HPeV3), is an important cause of sepsis-/meningitis-like illness in young infants. Laboratory records identified a total of ten HPeV-positive cases in Southeastern Australia between January and July 2019. The HPeV present in these cases were typed by Sanger sequencing of...

journal_title：Viruses

authors： Chamings A,Liew KC,Reid E,Athan E,Raditsis A,Vuillermin P,Yoga Y,Caly L,Druce J,Alexandersen S

更新日期：2019-10-03 00:00:00

abstract：:Phage lytic enzymes are enzymes produced by bacterial viruses, either as part of their virion to facilitate bacterial infection through local peptidoglycan degradation, or as soluble proteins to induce massive cell lysis at the end of the lytic replication cycle [...]. ...

journal_title：Viruses

authors： Briers Y

更新日期：2019-01-29 00:00:00

abstract：:Since deer were introduced into Australia in the mid-1800s, their wild populations have increased in size and distribution, posing a potential risk to the livestock industry, through their role in pathogen transmission cycles. In comparison to livestock, there are limited data on viral infections in all wildlife, incl...

journal_title：Viruses

authors： Huaman JL,Pacioni C,Forsyth DM,Pople A,Hampton JO,Carvalho TG,Helbig KJ

更新日期：2020-07-13 00:00:00

abstract：:Rotavirus causes severe gastroenteritis in children. Although vaccines are implemented, rotavirus-related diarrhea still claims ~200,000 lives annually worldwide, mainly in low-income settings, pointing to a need for improved vaccine tactics. To meet such a public health need, a P24-VP8* nanoparticle displaying the gl...

journal_title：Viruses

authors： Xia M,Huang P,Jiang X,Tan M

更新日期：2021-01-06 00:00:00