Astrovirus Diagnostics.

Abstract:

:Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, novel human astrovirus (HAstV) strains have been found in immunocompromised individuals in association with central nervous system (CNS) infections. This work reviews the past and current methods for astrovirus detection and their uses in both research laboratories and for medical diagnostic purposes.

journal_name

Viruses

journal_title

Viruses

authors

Pérot P,Lecuit M,Eloit M

doi

10.3390/v9010010

subject

Has Abstract

pub_date

2017-01-12 00:00:00

issue

1

issn

1999-4915

pii

v9010010

journal_volume

9

pub_type

杂志文章,评审
  • Echovirus 6 Infects Human Exocrine and Endocrine Pancreatic Cells and Induces Pro-Inflammatory Innate Immune Response.

    abstract::Human enteroviruses (HEV), especially coxsackievirus serotype B (CVB) and echovirus (E), have been associated with diseases of both the exocrine and endocrine pancreas, but so far evidence on HEV infection in human pancreas has been reported only in islets and ductal cells. This study aimed to investigate the capabili...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v9020025

    authors: Sarmiento L,Frisk G,Anagandula M,Hodik M,Barchetta I,Netanyah E,Cabrera-Rode E,Cilio CM

    更新日期:2017-01-30 00:00:00

  • Evaluation of Two Real-Time, TaqMan Reverse Transcription-PCR Assays for Detection of Rabies Virus in Circulating Variants from Argentina: Influence of Sequence Variation.

    abstract::In rabies diagnosis, it is essential to count on a rapid test to give a quick response. The combined sensitivity and robustness of the TaqMan RT-PCR assays (qRT-PCR) have made these methods a valuable alternative for rabies virus (RABV) detection. We conducted a study to compare the applicability of two widely used qR...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v13010023

    authors: Caraballo DA,Lombardo MA,Becker P,Sabio MS,Lema C,Martínez LM,Beltrán FJ,Li Y,Cisterna DM

    更新日期:2020-12-25 00:00:00

  • A Turkey-origin H9N2 Avian Influenza Virus Shows Low Pathogenicity but Different Within-Host Diversity in Experimentally Infected Turkeys, Quail and Ducks.

    abstract::Avian influenza virus (AIV) is a highly diverse and widespread poultry pathogen. Itsevolution and adaptation may be affected by multiple host and ecological factors, which are stillpoorly understood. In the present study, a turkey-origin H9N2 AIV was used as a model toinvestigate the within-host diversity of the virus...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12030319

    authors: Świętoń E,Tarasiuk K,Olszewska-Tomczyk M,Iwan E,Śmietanka K

    更新日期:2020-03-16 00:00:00

  • miRNAs as Potential Biomarkers for Viral Hepatitis B and C.

    abstract::Around 257 million people are living with hepatitis B virus (HBV) chronic infection and 71 million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead to liver complications such as cirrhosis and hepatocellular carcinoma (HCC). To take care of these chronically infected patients, one s...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v12121440

    authors: Loureiro D,Tout I,Narguet S,Benazzouz SM,Mansouri A,Asselah T

    更新日期:2020-12-14 00:00:00

  • Innovation in Newcastle Disease Virus Vectored Avian Influenza Vaccines.

    abstract::Highly pathogenic avian influenza (HPAI) and Newcastle disease are economically important avian diseases worldwide. Effective vaccination is critical to control these diseases in poultry. Live attenuated Newcastle disease virus (NDV) vectored vaccines have been developed for bivalent vaccination against HPAI viruses a...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v11030300

    authors: Kim SH,Samal SK

    更新日期:2019-03-26 00:00:00

  • Jan van der Noordaa (1934-2015); A Virologist Pur Sang.

    abstract::Our loyal friend and colleague, Jan van der Noordaa, passed away unexpectedly at the age of 80 on the evening of 17 June 2015. [...]. ...

    journal_title:Viruses

    pub_type: 传,历史文章,杂志文章

    doi:10.3390/v7092859

    authors: Berkhout B,Bukrinsky M

    更新日期:2015-09-15 00:00:00

  • Translation-Independent Roles of RNA Secondary Structures within the Replication Protein Coding Region of Turnip Crinkle Virus.

    abstract::RNA secondary structures play diverse roles in positive-sense (+) RNA virus infections, but those located with the replication protein coding sequence can be difficult to investigate. Structures that regulate the translation of replication proteins pose particular challenges, as their potential involvement in post-tra...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12030350

    authors: Sun R,Zhang S,Zheng L,Qu F

    更新日期:2020-03-22 00:00:00

  • Development of Antibodies with Broad Neutralization Specificities against HIV-1 after Long Term SHIV Infection in Macaques.

    abstract::Non-human primates (NHP) are the only animal model suitable to evaluate the protection efficacy of HIV-1 vaccines. It is important to understand how and when neutralizing antibodies (nAbs) with specificities similar to those of human broadly neutralizing antibodies (bnAbs) develop in NHPs. To address these questions, ...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12020163

    authors: Gao N,Gai Y,Meng L,Wang C,Zhang X,Wang W,Qin C,Yu X,Gao F

    更新日期:2020-01-31 00:00:00

  • Phage Lytic Enzymes.

    abstract::Phage lytic enzymes are enzymes produced by bacterial viruses, either as part of their virion to facilitate bacterial infection through local peptidoglycan degradation, or as soluble proteins to induce massive cell lysis at the end of the lytic replication cycle [...]. ...

    journal_title:Viruses

    pub_type: 社论

    doi:10.3390/v11020113

    authors: Briers Y

    更新日期:2019-01-29 00:00:00

  • The RNA Architecture of the SARS-CoV-2 3'-Untranslated Region.

    abstract::Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. The 3' untranslated region (UTR) of this β-CoV contains essential cis-acting RNA elements for the viral genome transcription and replication. These elements include an equilibrium between an extended bulged s...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12121473

    authors: Zhao J,Qiu J,Aryal S,Hackett JL,Wang J

    更新日期:2020-12-21 00:00:00

  • Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocket.

    abstract::The hydrophobic pocket in the HIV-1 gp41 N-terminal heptad repeat (NHR) domain plays an important role in viral fusion and entry into the host cell, and serves as an attractive target for development of HIV-1 fusion/entry inhibitors. The peptide anti-HIV drug targeting gp41 NHR, T-20 (generic name: enfuvirtide; brand ...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v5010127

    authors: Yu F,Lu L,Du L,Zhu X,Debnath AK,Jiang S

    更新日期:2013-01-11 00:00:00

  • Tomato Twisted Leaf Virus: A Novel Indigenous New World Monopartite Begomovirus Infecting Tomato in Venezuela.

    abstract::Begomoviruses are one of the major groups of plant viruses with an important economic impact on crop production in tropical and subtropical regions. The global spread of its polyphagous vector, the whitefly Bemisia tabaci, has contributed to the emergence and diversification of species within this genus. In this study...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11040327

    authors: Romay G,Geraud-Pouey F,Chirinos DT,Mahillon M,Gillis A,Mahillon J,Bragard C

    更新日期:2019-04-04 00:00:00

  • Small RNA NGS Revealed the Presence of Cherry Virus A and Little Cherry Virus 1 on Apricots in Hungary.

    abstract::Fruit trees, such as apricot trees, are constantly exposed to the attack of viruses. As they are propagated in a vegetative way, this risk is present not only in the field, where they remain for decades, but also during their propagation. Metagenomic diagnostic methods, based on next generation sequencing (NGS), offer...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10060318

    authors: Baráth D,Jaksa-Czotter N,Molnár J,Varga T,Balássy J,Szabó LK,Kirilla Z,Tusnády GE,Preininger É,Várallyay É

    更新日期:2018-06-11 00:00:00

  • Transcriptional Immune Signatures of Alveolar Macrophages and the Impact of the NLRP3 Inflammasome on Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Replication.

    abstract::Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral (PRRSV) disease in pigs characterized by poor reproductive health, increased mortality, and reductions in growth rates. PRRSV is known to implement immuno-antagonistic mechanisms to evade detection and mute host responses to infection. To bette...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12111299

    authors: Hicks JA,Yoo D,Liu HC

    更新日期:2020-11-12 00:00:00

  • Orchestrating the Selection and Packaging of Genomic RNA by Retroviruses: An Ensemble of Viral and Host Factors.

    abstract::Infectious retrovirus particles contain two copies of unspliced viral RNA that serve as the viral genome. Unspliced retroviral RNA is transcribed in the nucleus by the host RNA polymerase II and has three potential fates: (1) it can be spliced into subgenomic messenger RNAs (mRNAs) for the translation of viral protein...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v8090257

    authors: Kaddis Maldonado RJ,Parent LJ

    更新日期:2016-09-20 00:00:00

  • Surf and turf: mechanism of enhanced virus spread during poxvirus infection.

    abstract::Commentary on Doceul, V.; Hollinshead, M.; van der Linden, L.; Smith, G.L. Repulsion of superinfecting virions: a mechanism for rapid virus spread. Science2010, 327, 873-876. ...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v2051050

    authors: Condit RC

    更新日期:2010-05-01 00:00:00

  • Influenza Virus Infections and Cellular Kinases.

    abstract::Influenza A viruses (IAVs) are a major cause of respiratory illness and are responsible for yearly epidemics associated with more than 500,000 annual deaths globally. Novel IAVs may cause pandemic outbreaks and zoonotic infections with, for example, highly pathogenic avian influenza virus (HPAIV) of the H5N1 and H7N9 ...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v11020171

    authors: Meineke R,Rimmelzwaan GF,Elbahesh H

    更新日期:2019-02-20 00:00:00

  • Hepatitis E Pathogenesis.

    abstract::Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understanding of the pathog...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v8080212

    authors: Lhomme S,Marion O,Abravanel F,Chapuy-Regaud S,Kamar N,Izopet J

    更新日期:2016-08-05 00:00:00

  • Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates.

    abstract::Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain. The objective of this study was to determine whether HuNoV-lettuce binding...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11090833

    authors: Esseili MA,Gao X,Boley P,Hou Y,Saif LJ,Brewer-Jensen P,Lindesmith LC,Baric RS,Atmar RL,Wang Q

    更新日期:2019-09-08 00:00:00

  • Defining the Enterovirus Diversity Landscape of a Fecal Sample: A Methodological Challenge?

    abstract::Enteroviruses are a group of over 250 naked icosahedral virus serotypes that have been associated with clinical conditions that range from intrauterine enterovirus transmission withfataloutcome through encephalitis and meningitis, to paralysis. Classically, enterovirus detection was done by assaying for the developmen...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v8010018

    authors: Faleye TO,Adewumi MO,Adeniji JA

    更新日期:2016-01-12 00:00:00

  • Role of innate immunity against human papillomavirus (HPV) infections and effect of adjuvants in promoting specific immune response.

    abstract::During the early stages of human papillomavirus (HPV) infections, the innate immune system creates a pro-inflammatory microenvironment by recruiting innate immune cells to eliminate the infected cells, initiating an effective acquired immune response. However, HPV exhibits a wide range of strategies for evading immune...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v5112624

    authors: Amador-Molina A,Hernández-Valencia JF,Lamoyi E,Contreras-Paredes A,Lizano M

    更新日期:2013-10-28 00:00:00

  • In Vitro Inhibition of Zika Virus Replication with Poly(Sodium 4-Styrenesulfonate).

    abstract::Zika virus (ZIKV) is an emerging mosquito-borne pathogen associated with microcephaly and other congenital abnormalities in newborns as well as neurologic complications in adults. The explosive transmission of the virus in the last ten years put it in the limelight and improved our understanding of its biology and pat...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12090926

    authors: Botwina P,Obłoza M,Szczepański A,Szczubiałka K,Nowakowska M,Pyrć K

    更新日期:2020-08-23 00:00:00

  • Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts.

    abstract::The hepatitis B virus (HBV) infects hepatocytes, which are the main cell type composing a human liver. However, the liver is enriched with immune cells, particularly innate cells (e.g., myeloid cells, natural killer and natural killer T-cells (NK/NKT), dendritic cells (DCs)), in resting condition. Hence, the study of ...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v9050095

    authors: Faure-Dupuy S,Lucifora J,Durantel D

    更新日期:2017-04-28 00:00:00

  • Diversity and Evolution of Viral Pathogen Community in Cave Nectar Bats (Eonycteris spelaea).

    abstract::Bats are unique mammals, exhibit distinctive life history traits and have unique immunological approaches to suppression of viral diseases upon infection. High-throughput next-generation sequencing has been used in characterizing the virome of different bat species. The cave nectar bat, Eonycteris spelaea, has a broad...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11030250

    authors: Mendenhall IH,Wen DLH,Jayakumar J,Gunalan V,Wang L,Mauer-Stroh S,Su YCF,Smith GJD

    更新日期:2019-03-12 00:00:00

  • Application of CRISPR/Cas9 Gene Editing System on MDV-1 Genome for the Study of Gene Function.

    abstract::Marek's disease virus (MDV) is a member of alphaherpesviruses associated with Marek's disease, a highly contagious neoplastic disease in chickens. Complete sequencing of the viral genome and recombineering techniques using infectious bacterial artificial chromosome (BAC) clones of Marek's disease virus genome have ide...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10060279

    authors: Zhang Y,Tang N,Sadigh Y,Baigent S,Shen Z,Nair V,Yao Y

    更新日期:2018-05-24 00:00:00

  • Biochemical and Biophysical Characterization of the dsDNA Packaging Motor from the Lactococcus lactis Bacteriophage Asccphi28.

    abstract::Double-stranded DNA viruses package their genomes into pre-assembled protein procapsids. This process is driven by macromolecular motors that transiently assemble at a unique vertex of the procapsid and utilize homomeric ring ATPases to couple genome encapsidation to ATP hydrolysis. Here, we describe the biochemical a...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v13010015

    authors: Reyes-Aldrete E,Dill EA,Bussetta C,Szymanski MR,Diemer G,Maindola P,White MA,Bujalowski WM,Choi KH,Morais MC

    更新日期:2020-12-23 00:00:00

  • Preparation, Characterization and Diagnostic Valuation of Two Novel Anti-HPV16 E7 Oncoprotein Monoclonal Antibodies.

    abstract::At present, the clinical detection method of human papillomavirus (HPV) is mainly based on the PCR method. However, this method can only be used to detect HPV DNA and HPV types, and cannot be used to accurately predict cervical cancer. HPV16 E7 is an oncoprotein selectively expressed in cervical cancers. In this study...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12030333

    authors: Hu R,Dong Z,Zhang K,Pan G,Li C,Cui H

    更新日期:2020-03-19 00:00:00

  • Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation.

    abstract::The most highly expressed protein during the productive phase of the human papillomavirus (HPV) life cycle is E1^E4. Its full role during infection remains to be established. HPV E1^E4 is expressed during both the early and late stages of the virus life cycle and contributes to viral genome amplification. In an attemp...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v9120385

    authors: Biryukov J,Myers JC,McLaughlin-Drubin ME,Griffin HM,Milici J,Doorbar J,Meyers C

    更新日期:2017-12-19 00:00:00

  • Phosphorylation of Single Stranded RNA Virus Proteins and Potential for Novel Therapeutic Strategies.

    abstract::Post translational modification of proteins is a critical requirement that regulates function. Among the diverse kinds of protein post translational modifications, phosphorylation plays essential roles in protein folding, protein:protein interactions, signal transduction, intracellular localization, transcription regu...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v7102872

    authors: Keck F,Ataey P,Amaya M,Bailey C,Narayanan A

    更新日期:2015-10-12 00:00:00

  • Autophagy Promotes Infectious Particle Production of Mopeia and Lassa Viruses.

    abstract::Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related Old-World mammarenaviruses. LASV causes severe hemorrhagic fever with high mortality in humans, whereas no case of MOPV infection has been reported. Comparing MOPV and LASV is a powerful strategy to unravel pathogenic mechanisms that occur during the c...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11030293

    authors: Baillet N,Krieger S,Journeaux A,Caro V,Tangy F,Vidalain PO,Baize S

    更新日期:2019-03-23 00:00:00