Gammaherpesviral Tegument Proteins, PML-Nuclear Bodies and the Ubiquitin-Proteasome System.

abstract：:Emerging viruses have caused concerns about pollinator population declines, as multi-host RNA viruses may pose a health threat to pollinators and associated arthropods. In order to understand the ecology and impact these viruses have, we studied their host range and determined to what extent host and spatial variation...

journal_title：Viruses

authors： Dobelmann J,Felden A,Lester PJ

更新日期：2020-03-24 00:00:00

abstract：:Enteroviruses are small RNA viruses that affect millions of people each year by causing an important burden of disease with a broad spectrum of symptoms. In routine diagnostic laboratories, enteroviruses are identified by PCR-based methods, often combined with partial sequencing for genotyping. In this proof-of-princi...

journal_title：Viruses

authors： Grädel C,Terrazos Miani MA,Baumann C,Barbani MT,Neuenschwander S,Leib SL,Suter-Riniker F,Ramette A

更新日期：2020-07-31 00:00:00

abstract：:In Europe, cowpox virus (CPXV) infection in South American camelids occurs as a so-called spill-over infection. Although infected animals generally have a mild form of the disease and survive, cases of fatal generalised CPXV infection have also been described. Prevention by prophylactic vaccination is the only way to ...

journal_title：Viruses

authors： Prkno A,Hoffmann D,Kaiser M,Goerigk D,Pfeffer M,Winter K,Vahlenkamp TW,Beer M,Starke A

更新日期：2020-02-20 00:00:00

abstract：:Noroviruses are the most common etiological agent of acute gastroenteritis worldwide. Despite their high infectivity, a subpopulation of individuals is resistant to infection and disease. This susceptibility is norovirus genotype-dependent and is largely mediated by the presence or absence of human histo-blood group a...

journal_title：Viruses

authors： Nordgren J,Svensson L

更新日期：2019-03-06 00:00:00

abstract：:Many geometric forms are found in nature, some of them adhering to mathematical laws or amazing aesthetic rules. One of the best-known examples in microbiology is the icosahedral shape of certain viruses with 20 triangular facets and 12 edges. What is less known, however, is that a complementary object displaying 12 f...

journal_title：Viruses

authors： Besson S,Vragniau C,Vassal-Stermann E,Dagher MC,Fender P

更新日期：2020-07-02 00:00:00

abstract：:Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man died as a result of renal and respiratory failure after admission to a hospital in Jeddah, Saudi A...

journal_title：Viruses

authors： Chafekar A,Fielding BC

更新日期：2018-02-24 00:00:00

abstract：:Respiratory viruses cause disease in humans characterized by an abrupt onset of symptoms. Studies in humans and animal models have shown that symptoms are not immediate and appear days or even weeks after infection. Since the initial symptoms are a manifestation of virus recognition by elements of the innate immune re...

journal_title：Viruses

authors： Hermesh T,Moltedo B,López CB,Moran TM

更新日期：2010-11-01 00:00:00

abstract：:Two sister orders of the brown macroalgae (class Phaeophyceae), the morphologically complex Laminariales (commonly referred to as kelp) and the morphologically simple Ectocarpales are natural hosts for the dsDNA phaeoviruses (family Phycodnaviridae) that persist as proviruses in the genomes of their hosts. We have pre...

journal_title：Viruses

authors： McKeown DA,Schroeder JL,Stevens K,Peters AF,Sáez CA,Park J,Rothman MD,Bolton JJ,Brown MT,Schroeder DC

更新日期：2018-08-05 00:00:00

abstract：:Over the past 15 years we have been investigating an alternative approach to treating HIV-1/AIDS, based on the creation of a disease-resistant immune system through transplantation of autologous, gene-modified (HIV-1-resistant) hematopoietic stem and progenitor cells (GM-HSPC). We propose that the expression of select...

journal_title：Viruses

authors： DiGiusto DL,Stan R,Krishnan A,Li H,Rossi JJ,Zaia JA

更新日期：2013-11-22 00:00:00

abstract：:Salmonid alphavirus (SAV) is the cause of pancreas disease and sleeping disease in farmed salmonid fish in Europe. The spread of these diseases has been difficult to control with biosecurity and current vaccination strategies, and increased understanding of the viral pathogenesis could be beneficial for the developmen...

journal_title：Viruses

authors： Aksnes I,Markussen T,Braaen S,Rimstad E

更新日期：2020-09-24 00:00:00

abstract：:Bats are an important source of viral zoonoses, including paramyxoviruses. The paramyxoviral Pararubulavirus genus contains viruses mostly derived from bats that are common, diverse, distributed throughout the Old World, and known to be zoonotic. Here, we describe a new member of the genus Achimota pararubulavirus 3 (...

journal_title：Viruses

authors： Baker KS,Tachedjian M,Barr J,Marsh GA,Todd S,Crameri G,Crameri S,Smith I,Holmes CEG,Suu-Ire R,Fernandez-Loras A,Cunningham AA,Wood JLN,Wang LF

更新日期：2020-10-30 00:00:00

abstract：:Emerging evidence highlights a critical role for protein acetylation during herpesvirus infection. As prominent modulators of protein acetylation, histone deacetylases (HDACs) are essential transcriptional and epigenetic regulators. Not surprisingly, viruses have evolved a wide array of mechanisms to subvert HDAC func...

journal_title：Viruses

authors： Guise AJ,Budayeva HG,Diner BA,Cristea IM

更新日期：2013-06-27 00:00:00

abstract：:Arboviruses continue to be a significant global health concern. The unbiased metagenomic analyses of mosquito-borne and mosquito-specific viruses are useful to understand viral diversity and for the surveillance of pathogens of medical and veterinary importance. Metagenomic analysis was conducted on 6368 mosquitoes (7...

journal_title：Viruses

authors： Sanborn MA,Klein TA,Kim HC,Fung CK,Figueroa KL,Yang Y,Asafo-Adjei EA,Jarman RG,Hang J

更新日期：2019-03-05 00:00:00

abstract：:Begomoviruses are one of the major groups of plant viruses with an important economic impact on crop production in tropical and subtropical regions. The global spread of its polyphagous vector, the whitefly Bemisia tabaci, has contributed to the emergence and diversification of species within this genus. In this study...

journal_title：Viruses

authors： Romay G,Geraud-Pouey F,Chirinos DT,Mahillon M,Gillis A,Mahillon J,Bragard C

更新日期：2019-04-04 00:00:00

abstract：:Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by photosensitization has been applied with success since the first decades of the last century. Due to the fact that mammalian viruses are known to p...

journal_title：Viruses

authors： Costa L,Faustino MA,Neves MG,Cunha A,Almeida A

更新日期：2012-07-01 00:00:00

abstract：:Herpesviruses use a vesicle-mediated transfer of intranuclearly assembled nucleocapsids through the nuclear envelope (NE) for final maturation in the cytoplasm. The molecular basis for this novel vesicular nucleo-cytoplasmic transport is beginning to be elucidated in detail. The heterodimeric viral nuclear egress comp...

journal_title：Viruses

authors： Mettenleiter TC

更新日期：2016-09-27 00:00:00

abstract：:RNA interference (RNAi) was shown over 18 years ago to be a mechanism by which arbovirus replication and transmission could be controlled in arthropod vectors. During the intervening period, research on RNAi has defined many of the components and mechanisms of this antiviral pathway in arthropods, yet a number of unex...

journal_title：Viruses

authors： Blair CD,Olson KE

更新日期：2015-02-17 00:00:00

abstract：:Environmental and agricultural pollination services by honey bees, Apis mellifera, and honey production are compromised by high levels of annual colony losses globally. The majority are associated with disease caused by deformed wing virus (DWV), a positive-strand RNA virus, exacerbated by the ectoparasitic mite Varro...

journal_title：Viruses

authors： Gusachenko ON,Woodford L,Balbirnie-Cumming K,Campbell EM,Christie CR,Bowman AS,Evans DJ

更新日期：2020-05-12 00:00:00

abstract：:Cucurbit yellow stunting disorder virus (CYSDV), a bipartite whitefly-transmitted virus, constitutes a major threat to commercial cucurbit production worldwide. Here, construction of full-length CYSDV RNA1 and RNA2 cDNA clones allowed the in vitro synthesis of RNA transcripts able to replicate in cucumber protoplasts....

journal_title：Viruses

authors： Owen CA,Moukarzel R,Huang X,Kassem MA,Eliasco E,Aranda MA,Coutts RH,Livieratos IC

更新日期：2016-06-14 00:00:00

abstract：:The assembly of a hexameric lattice of retroviral immature particles requires the involvement of cell factors such as proteins and small molecules. A small, negatively charged polyanionic molecule, myo-inositol hexaphosphate (IP6), was identified to stimulate the assembly of immature particles of HIV-1 and other lenti...

journal_title：Viruses

authors： Dostálková A,Vokatá B,Kaufman F,Ulbrich P,Ruml T,Rumlová M

更新日期：2021-01-18 00:00:00

abstract：:The feline immunodeficiency virus (FIV) vaccine called Fel-O-Vax® FIV is the first commercial FIV vaccine released worldwide for the use in domestic cats against global FIV subtypes (A⁻E). This vaccine consists of inactivated dual-subtype (A plus D) FIV-infected cells, whereas its prototype vaccine consists of inactiv...

journal_title：Viruses

authors： Sahay B,Yamamoto JK

更新日期：2018-05-22 00:00:00

abstract：:Commentary on Doceul, V.; Hollinshead, M.; van der Linden, L.; Smith, G.L. Repulsion of superinfecting virions: a mechanism for rapid virus spread. Science2010, 327, 873-876. ...

journal_title：Viruses

authors： Condit RC

更新日期：2010-05-01 00:00:00

abstract：:Kaposi's sarcoma associated herpesvirus (KSHV), like other human herpes viruses, establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic phases. The latent phase is characterized by the persistence of viral episomes in a highly ordered chromatin structure and with the expression of ...

journal_title：Viruses

authors： Uppal T,Banerjee S,Sun Z,Verma SC,Robertson ES

更新日期：2014-12-11 00:00:00

abstract：:Viruses were recognized as the causative agents of fish diseases, such as infectious pancreatic necrosis and Oregon sockeye disease, in the early 1960s [1], and have since been shown to be responsible for diseases in all marine life from bacteria to protists, mollusks, crustaceans, fish and mammals [2].[...]. ...

journal_title：Viruses

authors： Middelboe M,Brussaard CPD

更新日期：2017-10-18 00:00:00

abstract：:: Rabies virus (RABV) is the only lyssavirus known to be present within the Caribbean. The island of Trinidad, is richly diverse in chiropteran fauna and endemic for bat-transmitted rabies with low RABV isolation rates observed in this population. We aimed to determine the seroprevalence of rabies virus neutralizing a...

journal_title：Viruses

authors： Seetahal JFR,Greenberg L,Satheshkumar PS,Sanchez-Vazquez MJ,Legall G,Singh S,Ramkissoon V,Schountz T,Munster V,Oura CAL,Carrington CVF

更新日期：2020-02-05 00:00:00

abstract：:Alfuy (ALFV) is an attenuated flavivirus related to the Murray Valley encephalitis virus (MVEV). We previously identified markers of attenuation in the envelope (E) protein of the prototype strain (ALFV3929), including the hinge region (E273-277) and lack of glycosylation at E154-156. To further determine the mechanis...

journal_title：Viruses

authors： Westlake D,Bielefeldt-Ohmann H,Prow NAA,Hall RAA

更新日期：2021-01-20 00:00:00

abstract：:Endemic to West Africa and South America, mammalian arenaviruses can cross the species barrier from their natural rodent hosts to humans, resulting in illnesses ranging from mild flu-like syndromes to severe and fatal haemorrhagic zoonoses. The increased frequency of outbreaks and associated high fatality rates of the...

journal_title：Viruses

authors： Stott RJ,Strecker T,Foster TL

更新日期：2020-07-21 00:00:00

abstract：:HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we found that exosomes, a type of extracellular vesicle (EV), from uninfected cells activate the transcription of HIV-1 ...

journal_title：Viruses

authors： Barclay RA,Mensah GA,Cowen M,DeMarino C,Kim Y,Pinto DO,Erickson J,Kashanchi F

更新日期：2020-06-19 00:00:00

abstract：:The smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae), is an economically important pest of tea in Japan. Previous work showed that a fast-killing nucleopolyhedrovirus (NPV) isolated from A. orana (AdorNPV) and a slow-killing NPV isolated from A. honmai (AdhoNPV) are both infectious to A. honmai larvae...

journal_title：Viruses

authors： Takahashi M,Nakai M,Saito Y,Sato Y,Ishijima C,Kunimi Y

更新日期：2015-03-18 00:00:00

abstract：:Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and mortality and posing a great threat to human health. Because of the diversity of influenza virus strains and drug resistance to the current direct antiviral agents, there ha...

journal_title：Viruses

authors： Zhang L,Chen J,Ke C,Zhang H,Zhang S,Tang W,Liu C,Liu G,Chen S,Hu A,Sun W,Xiao Y,Liu M,Chen X

更新日期：2020-05-18 00:00:00