Histone deacetylases in herpesvirus replication and virus-stimulated host defense.

abstract：:Innate immunity is the first line of defense against viral infection, and in turn, viruses have evolved to evade host immune surveillance. As a result, viruses may persist in host and develop chronic infections. Type I interferons (IFN-α/β) are among the most potent antiviral cytokines triggered by viral infections. P...

journal_title：Viruses

authors： Sun Y,Han M,Kim C,Calvert JG,Yoo D

更新日期：2012-04-01 00:00:00

abstract：:In July 2018, a novel avian influenza virus (A/Mandarin duck/South Korea/KNU18-12/2018(H11N9)) was isolated from Mandarin ducks in South Korea. Phylogenetic and molecular analyses were conducted to characterize the genetic origins of the H11N9 strain. Phylogenetic analysis indicated that eight gene segments of strain ...

journal_title：Viruses

authors： Tuong HT,Nguyen NM,Sung HW,Park H,Yeo SJ

更新日期：2020-02-12 00:00:00

abstract：:Bombyx mori nuclear polyhedrosis virus (BmNPV) is an important pathogen of silkworms. Despite extensive studies in recent decades, the interaction between BmNPV and host cells is still not clearly understood. Autophagy is an intrinsic innate immune mechanism and it controls infection autonomously in virus-infected cel...

journal_title：Viruses

authors： Wang,Xiao Q,Zhou XL,Zhu Y,Dong ZQ,Chen P,Pan MH,Lu C

更新日期：2017-12-30 00:00:00

abstract：:Delivering rapid protection against infectious agents to non-immune populations is a formidable public health challenge. Although passive immunotherapy is a fast and effective method of protection, large-scale production and administration of monoclonal antibodies (mAbs) is expensive and unpractical. Viral vector-medi...

journal_title：Viruses

authors： Michelini Z,Minkoff JM,Yang J,Negri D,Cara A,Hanson BJ,Salvatore M

更新日期：2020-12-17 00:00:00

abstract：:Influenza is a serious public health concern worldwide, as it causes significant morbidity and mortality. The emergence of drug-resistant viral strains requires new approaches for the treatment of influenza. In this study, Rubus coreanus seed (RCS) that is left over from the production of wine or juice was found to sh...

journal_title：Viruses

authors： Lee JH,Oh M,Seok JH,Kim S,Lee DB,Bae G,Bae HI,Bae SY,Hong YM,Kwon SO,Lee DH,Song CS,Mun JY,Chung MS,Kim KH

更新日期：2016-06-06 00:00:00

abstract：:In Europe, cowpox virus (CPXV) infection in South American camelids occurs as a so-called spill-over infection. Although infected animals generally have a mild form of the disease and survive, cases of fatal generalised CPXV infection have also been described. Prevention by prophylactic vaccination is the only way to ...

journal_title：Viruses

authors： Prkno A,Hoffmann D,Kaiser M,Goerigk D,Pfeffer M,Winter K,Vahlenkamp TW,Beer M,Starke A

更新日期：2020-02-20 00:00:00

abstract：:Arctic marine ecosystems are currently undergoing rapid changes in temperature and light availability. Picophytoplankton, such as Micromonas polaris, are predicted to benefit from such changes. However, little is known about how these environmental changes affect the viruses that exert a strong mortality pressure on t...

journal_title：Viruses

authors： Piedade GJ,Wesdorp EM,Montenegro-Borbolla E,Maat DS,Brussaard CPD

更新日期：2018-11-29 00:00:00

abstract：:MicroRNAs (miRNAs) are non-coding but functional RNA molecules of 21-25 nucleotides in length. MiRNAs play significant regulatory roles in diverse plant biological processes. In order to decipher the relationship between nbe-miR1919c-5p and the accumulations of tobacco curly shoot virus (TbCSV) and its betasatellite (...

journal_title：Viruses

authors： Du J,Wu R,Liu Z,Sun M,Ghanem H,Li M,Wu G,Qing L

更新日期：2020-04-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus that causes cancer (Adult T cell Leukemia, ATL) and a spectrum of inflammatory diseases (mainly HTLV-associated myelopathy-tropical spastic paraparesis, HAM/TSP). Since virions are particularly unstable, HTLV-1 transmission primarily occurs by transfer of a c...

journal_title：Viruses

authors： Carpentier A,Barez PY,Hamaidia M,Gazon H,de Brogniez A,Perike S,Gillet N,Willems L

更新日期：2015-07-07 00:00:00

abstract：:During flavivirus infection, some viral proteins move to the nucleus and cellular components are relocated from the nucleus to the cytoplasm. Thus, the integrity of the main regulator of the nuclear-cytoplasmic transport, the nuclear pore complex (NPC), was evaluated during infection with dengue virus (DENV) and Zika ...

journal_title：Viruses

authors： De Jesús-González LA,Cervantes-Salazar M,Reyes-Ruiz JM,Osuna-Ramos JF,Farfán-Morales CN,Palacios-Rápalo SN,Pérez-Olais JH,Cordero-Rivera CD,Hurtado-Monzón AM,Ruíz-Jiménez F,Gutiérrez-Escolano AL,Del Ángel RM

更新日期：2020-05-26 00:00:00

abstract：:The environmental factors that lead to the reactivation of human T cell leukemia virus type-1 (HTLV-I) in latently infected T cells in vivo remain unknown. It has been previously shown that heat shock (HS) is a potent inducer of HTLV-I viral protein expression in long-term cultured cell lines. However, the precise HTL...

journal_title：Viruses

authors： Kunihiro M,Fujii H,Miyagi T,Takahashi Y,Tanaka R,Fukushima T,Ansari AA,Tanaka Y

更新日期：2016-07-11 00:00:00

abstract：:Foot-and-mouth disease virus (FMDV) causes a highly contagious disease with catastrophic economic impact for affected countries. BHK21 suspension cells are preferred for the industrial production of FMDV vaccine antigen, but not all virus strains can be successfully propagated in these cells. Serotype Asia-1 is often ...

journal_title：Viruses

authors： Dill V,Hoffmann B,Zimmer A,Beer M,Eschbaumer M

更新日期：2017-08-18 00:00:00

abstract：:Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress toward...

journal_title：Viruses

authors： Schindewolf C,Menachery VD

更新日期：2019-01-17 00:00:00

abstract：:BST-2 or tetherin is a host cell restriction factor that prevents the budding of enveloped viruses at the cell surface, thus impairing the viral spread. Several countermeasures to evade this antiviral factor have been positively selected in retroviruses: the human immunodeficiency virus type 2 (HIV-2) relies on the en...

journal_title：Viruses

authors： Dufrasne FE,Lombard C,Goubau P,Ruelle J

更新日期：2016-10-14 00:00:00

abstract：:Specific chromatin immunoprecipitation of salt-fractionated infected cell extracts has demonstrated that the CCCTC-binding factor (CTCF), a highly conserved, 11-zinc-finger DNA-binding protein with known roles in cellular and viral genome organization and gene expression, specifically binds the genome of Minute Virus ...

journal_title：Viruses

authors： Boftsi M,Majumder K,Burger LR,Pintel DJ

更新日期：2020-11-30 00:00:00

abstract：:Post translational modification of proteins is a critical requirement that regulates function. Among the diverse kinds of protein post translational modifications, phosphorylation plays essential roles in protein folding, protein:protein interactions, signal transduction, intracellular localization, transcription regu...

journal_title：Viruses

authors： Keck F,Ataey P,Amaya M,Bailey C,Narayanan A

更新日期：2015-10-12 00:00:00

abstract：:Three dsRNAs, in sizes of approximately 2.5⁻5 kbp, were detected in the plant pathogenic fungus Nigrospora oryzae strain CS-7.5-4. Genomic analysis showed that the 5.0 kb dsRNA was a victorivirus named as Nigrospora oryzae victorivirus 2 (NoRV2). The genome of NoRV2 was 5166 bp in length containing two overlapping ope...

journal_title：Viruses

authors： Liu H,Liu R,Li CX,Wang H,Zhu HJ,Gao BD,Zhou Q,Zhong J

更新日期：2019-01-19 00:00:00

abstract：:During the early stages of human papillomavirus (HPV) infections, the innate immune system creates a pro-inflammatory microenvironment by recruiting innate immune cells to eliminate the infected cells, initiating an effective acquired immune response. However, HPV exhibits a wide range of strategies for evading immune...

journal_title：Viruses

authors： Amador-Molina A,Hernández-Valencia JF,Lamoyi E,Contreras-Paredes A,Lizano M

更新日期：2013-10-28 00:00:00

abstract：:Chronic hepatitis C virus (HCV) infection is a major cause of liver disease and hepatocellular carcinoma (HCC)-the second leading, and rising, cause of death due to cancer world-wide [...]. ...

journal_title：Viruses

authors： Baumert TF,Hoshida Y

更新日期：2019-05-15 00:00:00

abstract：:Insectivorous bats are speculated to be ancestral hosts of Middle-East respiratory syndrome (MERS) coronavirus (CoV). MERS-CoV causes disease in humans with thirty-five percent fatality, and has evolved proteins that counteract human antiviral responses. Since bats experimentally infected with MERS-CoV do not develop ...

journal_title：Viruses

authors： Banerjee A,Falzarano D,Rapin N,Lew J,Misra V

更新日期：2019-02-13 00:00:00

abstract：:Microvirin (MVN) is one of the human immunodeficiency virus (HIV-1) entry inhibitor lectins, which consists of two structural domains sharing 35% sequence identity and contrary to many other antiviral lectins, it exists as a monomer. In this study, we engineered an MVN variant, LUMS1, consisting of two domains with 10...

journal_title：Viruses

authors： Shahid M,Qadir A,Yang J,Ahmad I,Zahid H,Mirza S,Windisch MP,Shahzad-Ul-Hussan S

更新日期：2020-02-11 00:00:00

abstract：:Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed. Spontaneous resolution of infection is associated with effective host adaptive immunity t...

journal_title：Viruses

authors： Tarr AW,Urbanowicz RA,Ball JK

更新日期：2012-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) is a causative agent of acquired immune deficiency syndrome (AIDS). Highly active antiretroviral therapy (HAART) can slow down the replication of HIV-1, leading to an improvement in the survival of HIV-1-infected patients. However, drug toxicities and poor drug administration has led...

journal_title：Viruses

authors： Chupradit K,Moonmuang S,Nangola S,Kitidee K,Yasamut U,Mougel M,Tayapiwatana C

更新日期：2017-09-29 00:00:00

abstract：:The development of high-throughput technologies allows for evaluating gene expression at the whole-genome level. Together with proteomic and metabolomic studies, these analyses have resulted in the identification of plant genes whose function or expression is altered as a consequence of pathogen attacks. Members of th...

journal_title：Viruses

authors： Czosnek H,Eybishtz A,Sade D,Gorovits R,Sobol I,Bejarano E,Rosas-Díaz T,Lozano-Durán R

更新日期：2013-03-22 00:00:00

abstract：:Enteroviruses are a group of over 250 naked icosahedral virus serotypes that have been associated with clinical conditions that range from intrauterine enterovirus transmission withfataloutcome through encephalitis and meningitis, to paralysis. Classically, enterovirus detection was done by assaying for the developmen...

journal_title：Viruses

authors： Faleye TO,Adewumi MO,Adeniji JA

更新日期：2016-01-12 00:00:00

abstract：:About 70% of all Ewing sarcoma (EWS) patients are diagnosed under the age of 20 years. Over the last decades little progress has been made towards finding effective treatment approaches for primarily metastasized or refractory Ewing sarcoma in young patients. Here, in the context of the search for novel therapeutic op...

journal_title：Viruses

authors： Lacroix J,Kis Z,Josupeit R,Schlund F,Stroh-Dege A,Frank-Stöhr M,Leuchs B,Schlehofer JR,Rommelaere J,Dinsart C

更新日期：2018-06-03 00:00:00

abstract：:Influenza A virus (IAV) has caused seasonal influenza epidemics and influenza pandemics, which resulted in serious threat to public health and socioeconomic impacts. Until now, only 5 drugs belong to two categories are used for prophylaxis and treatment of IAV infection. Hemagglutinin (HA), the envelope glycoprotein o...

journal_title：Viruses

authors： Yang J,Li M,Shen X,Liu S

更新日期：2013-01-22 00:00:00

abstract：:Respiratory viruses cause disease in humans characterized by an abrupt onset of symptoms. Studies in humans and animal models have shown that symptoms are not immediate and appear days or even weeks after infection. Since the initial symptoms are a manifestation of virus recognition by elements of the innate immune re...

journal_title：Viruses

authors： Hermesh T,Moltedo B,López CB,Moran TM

更新日期：2010-11-01 00:00:00

abstract：:The mouse mammary tumor virus (MMTV) Pr77Gag polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be formed. This process requires specific recognition and packaging of dimerized genomic RNA (gRNA) by Gag during virus assembly. Most of the previous work on retrovira...

journal_title：Viruses

authors： Chameettachal A,Pillai VN,Ali LM,Pitchai FNN,Ardah MT,Mustafa F,Marquet R,Rizvi TA

更新日期：2018-06-18 00:00:00

abstract：:The smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae), is an economically important pest of tea in Japan. Previous work showed that a fast-killing nucleopolyhedrovirus (NPV) isolated from A. orana (AdorNPV) and a slow-killing NPV isolated from A. honmai (AdhoNPV) are both infectious to A. honmai larvae...

journal_title：Viruses

authors： Takahashi M,Nakai M,Saito Y,Sato Y,Ishijima C,Kunimi Y

更新日期：2015-03-18 00:00:00