Biochemical and Functional Characterization of Mouse Mammary Tumor Virus Full-Length Pr77Gag Expressed in Prokaryotic and Eukaryotic Cells.

abstract：:We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection p...

journal_title：Viruses

authors： Andreo V,Neteler M,Rocchini D,Provensal C,Levis S,Porcasi X,Rizzoli A,Lanfri M,Scavuzzo M,Pini N,Enria D,Polop J

更新日期：2014-01-14 00:00:00

abstract：:Thermobifida fusca is of biotechnological interest due to its ability to produce an array of plant cell wall hydrolytic enzymes. Nonetheless, only one T. fusca bacteriophage with genome information has been reported to date. This study was aimed at discovering more relevant bacteriophages to expand the existing knowle...

journal_title：Viruses

authors： Cheepudom J,Lin TL,Lee CC,Meng M

更新日期：2019-11-08 00:00:00

abstract：:Herpesviruses use a vesicle-mediated transfer of intranuclearly assembled nucleocapsids through the nuclear envelope (NE) for final maturation in the cytoplasm. The molecular basis for this novel vesicular nucleo-cytoplasmic transport is beginning to be elucidated in detail. The heterodimeric viral nuclear egress comp...

journal_title：Viruses

authors： Mettenleiter TC

更新日期：2016-09-27 00:00:00

abstract：:Arctic marine ecosystems are currently undergoing rapid changes in temperature and light availability. Picophytoplankton, such as Micromonas polaris, are predicted to benefit from such changes. However, little is known about how these environmental changes affect the viruses that exert a strong mortality pressure on t...

journal_title：Viruses

authors： Piedade GJ,Wesdorp EM,Montenegro-Borbolla E,Maat DS,Brussaard CPD

更新日期：2018-11-29 00:00:00

abstract：:With the availability of an increasing number of 3D structures of bacteriophage components, combined with powerful in silico predictive tools, it has become possible to decipher the structural assembly and functionality of phage adhesion devices. In the current study, we examined 113 members of the 936 group of lactoc...

journal_title：Viruses

authors： Hayes S,Mahony J,Vincentelli R,Ramond L,Nauta A,van Sinderen D,Cambillau C

更新日期：2019-07-09 00:00:00

abstract：:Countries rely on good diagnostic tests and appropriate testing schemes to fight against economically important small ruminant lentivirus (SRLV) infections. We undertook an extensive comparative analysis of seven commercially available serological tests and one in-house real-time PCR (qPCR) detecting genotype A and B ...

journal_title：Viruses

authors： Michiels R,Van Mael E,Quinet C,Adjadj NR,Cay AB,De Regge N

更新日期：2018-12-08 00:00:00

abstract：:Several viral factors impact the natural course of hepatitis B virus (HBV) infection, the sensitivity of diagnostic tests, or treatment response to interferon-α and nucleos(t)ide analogues. These factors include the viral genotype and serotype but also mutations affecting the HBV surface antigen, basal core promoter/p...

journal_title：Viruses

authors： Velkov S,Protzer U,Michler T

更新日期：2020-11-23 00:00:00

abstract：:Research on human enteroviruses has resulted in the identification of more than 100 enterovirus types, which use more than 10 protein receptors and/or attachment factors required in cell binding and initiation of the replication cycle. Many of these "viral" receptors are overexpressed in cancer cells. Receptor binding...

journal_title：Viruses

authors： Ylä-Pelto J,Tripathi L,Susi P

更新日期：2016-02-23 00:00:00

abstract：:Viruses represent important test cases for data federation due to their genome size and the rapid increase in sequence data in publicly available databases. However, some consequences of previously decentralized (unfederated) data are lack of consensus or comparisons between feature annotations. Unifying or displaying...

journal_title：Viruses

authors： Martí-Carreras J,Gener AR,Miller SD,Brito AF,Camacho CE,Connor R,Deboutte W,Glickman C,Kristensen DM,Meyer WK,Modha S,Norris AL,Saha S,Belford AK,Biederstedt E,Brister JR,Buchmann JP,Cooley NP,Edwards RA,Javkar K,

更新日期：2020-12-10 00:00:00

abstract：:At the end of my doctoral studies, in 1988, I published a review article on the major steps of transcription and translation during the mammalian reovirus multiplication cycle, a topic that still fascinates me 30 years later. It is in the nature of scientific research to generate further questioning as new knowledge e...

journal_title：Viruses

authors： Lemay G

更新日期：2018-11-27 00:00:00

abstract：:Bats are an important source of viral zoonoses, including paramyxoviruses. The paramyxoviral Pararubulavirus genus contains viruses mostly derived from bats that are common, diverse, distributed throughout the Old World, and known to be zoonotic. Here, we describe a new member of the genus Achimota pararubulavirus 3 (...

journal_title：Viruses

authors： Baker KS,Tachedjian M,Barr J,Marsh GA,Todd S,Crameri G,Crameri S,Smith I,Holmes CEG,Suu-Ire R,Fernandez-Loras A,Cunningham AA,Wood JLN,Wang LF

更新日期：2020-10-30 00:00:00

abstract：:Significantly higher numbers of human infections with H5N1 virus have occurred in Indonesia and Egypt, compared with other affected areas, and it is speculated that there are specific viral factors for human infection with avian H5N1 viruses in these locations. We previously showed PB2-K526R is present in 80% of Indon...

journal_title：Viruses

authors： Wang P,Song W,Mok BW,Zheng M,Lau SY,Liu S,Chen P,Huang X,Liu H,Cremin CJ,Chen H

更新日期：2019-03-22 00:00:00

abstract：:The Bunyaviridae is the largest family of RNA viruses, with over 350 members worldwide. Several of these viruses cause severe diseases in livestock and humans. With an increasing number and frequency of outbreaks, bunyaviruses represent a growing threat to public health and agricultural productivity globally. Yet, the...

journal_title：Viruses

authors： Albornoz A,Hoffmann AB,Lozach PY,Tischler ND

更新日期：2016-05-24 00:00:00

abstract：:The Vibrio cholerae biotype "El Tor" is responsible for all of the current epidemic and endemic cholera outbreaks worldwide. These outbreaks are clonal, and it is hypothesized that they originate from the coastal areas near the Bay of Bengal, where the lytic bacteriophage ICP1 (International Centre for Diarrhoeal Dise...

journal_title：Viruses

authors： Angermeyer A,Das MM,Singh DV,Seed KD

更新日期：2018-06-01 00:00:00

abstract：:Innate immunity is the first line of defense against viral infection, and in turn, viruses have evolved to evade host immune surveillance. As a result, viruses may persist in host and develop chronic infections. Type I interferons (IFN-α/β) are among the most potent antiviral cytokines triggered by viral infections. P...

journal_title：Viruses

authors： Sun Y,Han M,Kim C,Calvert JG,Yoo D

更新日期：2012-04-01 00:00:00

abstract：:Autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) are poorly understood autoimmune liver diseases. Immunosuppression is used to treat AIH and ursodeoxycholic acid is used to slow the progression of PBC. Nevertheless, a proportion of patients with both disorders progress to liver failure. Following liver t...

journal_title：Viruses

authors： Wasilenko ST,Montano-Loza AJ,Mason AL

更新日期：2013-01-24 00:00:00

abstract：:The extension of virology beyond its traditional medical, veterinary, or agricultural applications, now called environmental virology, has shown that viruses are both the most numerous and diverse biological entities on Earth. In particular, virus isolations from unicellular eukaryotic hosts (heterotrophic and photosy...

journal_title：Viruses

authors： Claverie JM

更新日期：2020-10-06 00:00:00

abstract：:A Pseudorabies virus (PRV) variant has emerged in China since 2011 that is not protected by commercial vaccines, and has not been well studied. The PRV genome is large and difficult to manipulate, but it is feasible to use clustered, regularly interspaced short palindromic repeats (CRISPR)/Cas9 technology. However, id...

journal_title：Viruses

authors： Tang YD,Liu JT,Fang QQ,Wang TY,Sun MX,An TQ,Tian ZJ,Cai XH

更新日期：2016-03-29 00:00:00

abstract：:Poxviruses are important pathogens of man and numerous domestic and wild animal species. Cross species (including zoonotic) poxvirus infections can have drastic consequences for the recipient host. Bats are a diverse order of mammals known to carry lethal viral zoonoses such as Rabies, Hendra, Nipah, and SARS. Consequ...

journal_title：Viruses

authors： Baker KS,Murcia PR

更新日期：2014-04-03 00:00:00

abstract：:Glycoprotein B (gB) plays an important role in alphaherpesvirus cellular entry and acts in concert with gD and the gH/gL complex. To evaluate whether functional differences exist between gB1 and gB4, the corresponding genes were exchanged between the two viruses. The gB4-containing-EHV-1 (EHV-1_gB4) recombinant virus ...

journal_title：Viruses

authors： Spiesschaert B,Osterrieder N,Azab W

更新日期：2015-02-03 00:00:00

abstract：:Mycoviruses infect a large number of diverse fungal species, but considering their prevalence, relatively few high-quality genome sequences have been determined. Many mycoviruses have linear double-stranded RNA genomes, which makes it technically challenging to ascertain their nucleotide sequence using conventional se...

journal_title：Viruses

authors： Crabtree AM,Kizer EA,Hunter SS,Van Leuven JT,New DD,Fagnan MW,Rowley PA

更新日期：2019-01-16 00:00:00

abstract：:Astroviral infection is considered to be one of the causes of mammalian diarrheal diseases. It has been shown that astrovirus infections cause varying degrees of diarrhea in turkeys and mice. However, the pathogenesis of porcine astrovirus is unknown. In this study, the virulence of a cytopathic porcine astrovirus (PA...

journal_title：Viruses

authors： Fang Q,Wang C,Liu H,Wu Q,Liang S,Cen M,Dong Q,Wei Y,Chen Y,Ouyang K,Wei Z,Huang W

更新日期：2019-12-13 00:00:00

abstract：:HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we found that exosomes, a type of extracellular vesicle (EV), from uninfected cells activate the transcription of HIV-1 ...

journal_title：Viruses

authors： Barclay RA,Mensah GA,Cowen M,DeMarino C,Kim Y,Pinto DO,Erickson J,Kashanchi F

更新日期：2020-06-19 00:00:00

abstract：:Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by photosensitization has been applied with success since the first decades of the last century. Due to the fact that mammalian viruses are known to p...

journal_title：Viruses

authors： Costa L,Faustino MA,Neves MG,Cunha A,Almeida A

更新日期：2012-07-01 00:00:00

abstract：:African swine fever (ASF) has become the major threat for the global swine industry. Furthermore, the epidemiological situation of African swine fever virus (ASFV) in some endemic regions of Sub-Saharan Africa is worse than ever, with multiple virus strains and genotypes currently circulating in a given area. Despite ...

journal_title：Viruses

authors： Lopez E,van Heerden J,Bosch-Camós L,Accensi F,Navas MJ,López-Monteagudo P,Argilaguet J,Gallardo C,Pina-Pedrero S,Salas ML,Salt J,Rodriguez F

更新日期：2020-12-21 00:00:00

abstract：:The human respiratory syncytial virus (hRSV) and human Metapneumovirus (hMPV) are two of the leading etiological agents of acute lower respiratory tract infections, which constitute the main cause of mortality in infants. However, there are currently approved vaccines for neither hRSV nor hMPV. Moreover, despite the s...

journal_title：Viruses

authors： Andrade CA,Pacheco GA,Gálvez NMS,Soto JA,Bueno SM,Kalergis AM

更新日期：2020-06-12 00:00:00

abstract：:While dromedaries are the immediate animal source of Middle East Respiratory Syndrome (MERS) epidemic, viruses related to MERS coronavirus (MERS-CoV) have also been found in bats as well as hedgehogs. To elucidate the evolution of MERS-CoV-related viruses and their interspecies transmission pathway, samples were colle...

journal_title：Viruses

authors： Lau SKP,Luk HKH,Wong ACP,Fan RYY,Lam CSF,Li KSM,Ahmed SS,Chow FWN,Cai JP,Zhu X,Chan JFW,Lau TCK,Cao K,Li M,Woo PCY,Yuen KY

更新日期：2019-10-24 00:00:00

abstract：:While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. Among 1779 bat samples collected in China, diverse coronaviruses were detected in 32 samples from five different bat species by RT-PCR. Two novel alpha...

journal_title：Viruses

authors： Lau SKP,Wong ACP,Zhang L,Luk HKH,Kwok JSL,Ahmed SS,Cai JP,Zhao PSH,Teng JLL,Tsui SKW,Yuen KY,Woo PCY

更新日期：2019-05-07 00:00:00

abstract：:Zika virus (ZIKV) is a vertically and sexually transmissible virus resulting in severe congenital malformation. The goal of this study was to develop an ovine model of ZIKV infection. Between 28-35 days gestation (DG), four pregnant animals were infected with two doses of 6 × 106 PFU of ZIKV; four control animals rece...

journal_title：Viruses

authors： Schwarz ER,Pozor MA,Pu R,Barr KL,Beachboard SE,MacLachlan NJ,Prakoso D,Long MT

更新日期：2019-08-29 00:00:00

abstract：:The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated in 2012, and circulated worldwide with high mortality. The continual outbreaks of MERS-CoV highlight the importance of developing antiviral therapeutics. Here, we rationally designed a novel fusion inhibitor named MERS-five-helix bundle (ME...

journal_title：Viruses

authors： Sun Y,Zhang H,Shi J,Zhang Z,Gong R

更新日期：2017-09-14 00:00:00