Prevalence of antibodies against hantaviruses in serum and saliva of adults living or working on farms in Yorkshire, United Kingdom.

Abstract:

:Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation of a Seoul hantavirus from rats trapped on the patient's farm, it was considered appropriate to further investigate the public health risk of this virus in the region. Of a total 119 individuals tested, nine (7.6%) were seropositive for hantavirus antibodies. Seven of the seropositive samples showed a stronger reaction to Seoul and Hantaan compared to other clinically relevant hantaviruses. Observation of rodents during the day, in particular mice, was associated with a reduced risk of seropositivity. In addition to one region known to be at risk following an acute case, five further potential risk areas have been identified. This study supports recently published evidence that hantaviruses are likely to be of public health interest in the region.

journal_name

Viruses

journal_title

Viruses

authors

Jameson LJ,Newton A,Coole L,Newman EN,Carroll MW,Beeching NJ,Hewson R,Christley RM

doi

10.3390/v6020524

subject

Has Abstract

pub_date

2014-02-05 00:00:00

pages

524-34

issue

2

issn

1999-4915

pii

v6020524

journal_volume

6

pub_type

杂志文章
  • Metagenomic Approach with the NetoVIR Enrichment Protocol Reveals Virus Diversity within Ethiopian Honey Bees (Apis mellifera simensis).

    abstract::Metagenomics studies have accelerated the discovery of novel or divergent viruses of the honey bee. However, most of these studies predominantly focused on RNA viruses, and many suffer from the relatively low abundance of viral nucleic acids in the samples (i.e., compared to that of the host). Here, we explored the vi...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12111218

    authors: Gebremedhn H,Deboutte W,Schoonvaere K,Demaeght P,De Smet L,Amssalu B,Matthijnssens J,de Graaf DC

    更新日期:2020-10-27 00:00:00

  • Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection.

    abstract::Andes orthohantavirus (ANDV) is an important human pathogen causing hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of 30% in Chile. Around 60% of all cases have a severe clinical course, while the others have a mild clinical course. The main goal of this study was to understand if the genetic variatio...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11080680

    authors: Ribeiro GE,Leon LE,Perez R,Cuiza A,Vial PA,Ferres M,Mertz GJ,Vial C

    更新日期:2019-07-25 00:00:00

  • Gammaherpesviral Tegument Proteins, PML-Nuclear Bodies and the Ubiquitin-Proteasome System.

    abstract::Gammaherpesviruses like Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) subvert the ubiquitin proteasome system for their own benefit in order to facilitate viral gene expression and replication. In particular, viral tegument proteins that share sequence homology to the formylglycineamide r...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v9100308

    authors: Full F,Hahn AS,Großkopf AK,Ensser A

    更新日期:2017-10-21 00:00:00

  • The role of bacterial chaperones in the circulative transmission of plant viruses by insect vectors.

    abstract::Persistent circulative transmission of plant viruses involves complex interactions between the transmitted virus and its insect vector. Several studies have shown that insect vector proteins are involved in the passage and the transmission of the virus. Interestingly, proteins expressed by bacterial endosymbionts that...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v5061516

    authors: Kliot A,Ghanim M

    更新日期:2013-06-19 00:00:00

  • Human cytomegalovirus US28 facilitates cell-to-cell viral dissemination.

    abstract::Human cytomegalovirus (HCMV) encodes a number of viral proteins with homology to cellular G protein-coupled receptors (GPCRs). These viral GPCRs, including US27, US28, UL33, and UL78, have been ascribed numerous functions during infection, including activating diverse cellular pathways, binding to immunomodulatory che...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v6031202

    authors: Noriega VM,Gardner TJ,Redmann V,Bongers G,Lira SA,Tortorella D

    更新日期:2014-03-12 00:00:00

  • Nipah Virus: Past Outbreaks and Future Containment.

    abstract::Viral outbreaks of varying frequencies and severities have caused panic and havoc across the globe throughout history. Influenza, small pox, measles, and yellow fever reverberated for centuries, causing huge burden for economies. The twenty-first century witnessed the most pathogenic and contagious virus outbreaks of ...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v12040465

    authors: Soman Pillai V,Krishna G,Valiya Veettil M

    更新日期:2020-04-20 00:00:00

  • Metagenomic Virome Analysis of Culex Mosquitoes from Kenya and China.

    abstract::Many blood-feeding arthropods are known vectors of viruses that are a source of unprecedented global health concern. Mosquitoes are an integral part of these arthropod vectors. Advancements in next-generation sequencing and bioinformatics has expanded our knowledge on the richness of viruses harbored by arthropods. In...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10010030

    authors: Atoni E,Wang Y,Karungu S,Waruhiu C,Zohaib A,Obanda V,Agwanda B,Mutua M,Xia H,Yuan Z

    更新日期:2018-01-12 00:00:00

  • Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses.

    abstract::Arthropod-borne flaviviruses are human pathogens of global medical importance, against which no effective small molecule-based antiviral therapy has currently been reported. Arbidol (umifenovir) is a broad-spectrum antiviral compound approved in Russia and China for prophylaxis and treatment of influenza. This compoun...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10040184

    authors: Haviernik J,Štefánik M,Fojtíková M,Kali S,Tordo N,Rudolf I,Hubálek Z,Eyer L,Ruzek D

    更新日期:2018-04-10 00:00:00

  • Investigation about the Occurrence of Transmission Cycles of Arbovirus in the Tropical Forest, Amazon Region.

    abstract::Because of its ecological characteristics, the Caxiuanã National Forest (FLONA) is a potential area of arbovirus circulation. The present study aimed to investigate the occurrence of arbovirus transmission cycles at FLONA de Caxiuanã. Five field trips were performed to capture mosquitoes and sylvatic vertebrates. For ...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11090774

    authors: Araújo PA,Freitas MO,Chiang JO,Silva FA,Chagas LL,Casseb SM,Silva SP,Nunes-Neto JP,Rosa-Júnior JW,Nascimento BS,Hernández LA,Paz TB,Barros LL,Silva EP,Azevedo RS,Martins LC,Ferreira MS,Vasconcelos PF

    更新日期:2019-08-22 00:00:00

  • The Characterization of Immunoprotection Induced by a cDNA Clone Derived from the Attenuated Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 Strain.

    abstract::The porcine epidemic diarrhea virus (PEDV) poses a great threat to the global swine industries and the unreliable protection induced by the currently available vaccines remains a major challenge. We previously generated a genogroup 2b (G2b) PEDV Taiwan Pintung 52 (PEDVPT) strain, PEDVPT-P96, and determined its promisi...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10100543

    authors: Kao CF,Chiou HY,Chang YC,Hsueh CS,Jeng CR,Tsai PS,Cheng IC,Pang VF,Chang HW

    更新日期:2018-10-04 00:00:00

  • Facing antibiotic resistance: Staphylococcus aureus phages as a medical tool.

    abstract::Staphylococcus aureus is a common and often virulent pathogen in humans. This bacterium is widespread, being present on the skin and in the nose of healthy people. Staphylococcus aureus can cause infections with severe outcomes ranging from pustules to sepsis and death. The introduction of antibiotics led to a general...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v6072551

    authors: Kaźmierczak Z,Górski A,Dąbrowska K

    更新日期:2014-07-01 00:00:00

  • Molecular characterization and phylogenetic analysis of new variants of the porcine epidemic diarrhea virus in Gansu, China in 2012.

    abstract::Between January 2012 and March 2012, the infection rates of porcine epidemic diarrhea virus (PEDV) increased substantially in vaccinated swine herds in many porcine farms in Gansu Province, China. The spike (S) glycoprotein is an important determinant for PEDV biological properties. To determine the distribution profi...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v5081991

    authors: Tian Y,Yu Z,Cheng K,Liu Y,Huang J,Xin Y,Li Y,Fan S,Wang T,Huang G,Feng N,Yang Z,Yang S,Gao Y,Xia X

    更新日期:2013-08-15 00:00:00

  • Marine Viruses: Key Players in Marine Ecosystems.

    abstract::Viruses were recognized as the causative agents of fish diseases, such as infectious pancreatic necrosis and Oregon sockeye disease, in the early 1960s [1], and have since been shown to be responsible for diseases in all marine life from bacteria to protists, mollusks, crustaceans, fish and mammals [2].[...]. ...

    journal_title:Viruses

    pub_type: 社论

    doi:10.3390/v9100302

    authors: Middelboe M,Brussaard CPD

    更新日期:2017-10-18 00:00:00

  • Equine Immunoglobulin and Equine Neutralizing F(ab')₂ Protect Mice from West Nile Virus Infection.

    abstract::West Nile virus (WNV) is prevalent in Africa, Europe, the Middle East, West Asia, and North America, and causes epidemic encephalitis. To date, no effective therapy for WNV infection has been developed; therefore, there is urgent need to find an efficient method to prevent WNV disease. In this study, we prepared and e...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v8120332

    authors: Cui J,Zhao Y,Wang H,Qiu B,Cao Z,Li Q,Zhang Y,Yan F,Jin H,Wang T,Sun W,Feng N,Gao Y,Sun J,Wang Y,Perlman S,Zhao J,Yang S,Xia X

    更新日期:2016-12-18 00:00:00

  • A Mechanism Underlying Attenuation of Recombinant Influenza A Viruses Carrying Reporter Genes.

    abstract::Influenza A viruses (IAV) carrying reporter genes provide a powerful tool to study viral infection and pathogenesis in vivo, however, incorporating a non-essential gene into the IAV genome often results in virus attenuation and genetic instability. Very few studies have systematically compared different reporter IAVs,...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10120679

    authors: Zhao X,Wang L,Cui Q,Li P,Wang Y,Zhang Y,Yang Y,Rong L,Du R

    更新日期:2018-11-30 00:00:00

  • Diversity and Evolution of Viral Pathogen Community in Cave Nectar Bats (Eonycteris spelaea).

    abstract::Bats are unique mammals, exhibit distinctive life history traits and have unique immunological approaches to suppression of viral diseases upon infection. High-throughput next-generation sequencing has been used in characterizing the virome of different bat species. The cave nectar bat, Eonycteris spelaea, has a broad...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11030250

    authors: Mendenhall IH,Wen DLH,Jayakumar J,Gunalan V,Wang L,Mauer-Stroh S,Su YCF,Smith GJD

    更新日期:2019-03-12 00:00:00

  • Addressing the Challenges of Hepatitis C Cure and Persistent Risk of Hepatocellular Carcinoma.

    abstract::Chronic hepatitis C virus (HCV) infection is a major cause of liver disease and hepatocellular carcinoma (HCC)-the second leading, and rising, cause of death due to cancer world-wide [...]. ...

    journal_title:Viruses

    pub_type: 社论

    doi:10.3390/v11050441

    authors: Baumert TF,Hoshida Y

    更新日期:2019-05-15 00:00:00

  • Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects.

    abstract::Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of HTLV-associated disease and viral dynamics. A subset of 45 human T-...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v8080221

    authors: Usadi B,Bruhn R,Lin J,Lee TH,Blackburn E,Murphy EL

    更新日期:2016-08-11 00:00:00

  • Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates.

    abstract::Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain. The objective of this study was to determine whether HuNoV-lettuce binding...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v11090833

    authors: Esseili MA,Gao X,Boley P,Hou Y,Saif LJ,Brewer-Jensen P,Lindesmith LC,Baric RS,Atmar RL,Wang Q

    更新日期:2019-09-08 00:00:00

  • Human cytomegalovirus encoded homologs of cytokines, chemokines and their receptors: roles in immunomodulation.

    abstract::Human cytomegalovirus (HCMV), the largest human herpesvirus, infects a majority of the world's population. Like all herpesviruses, following primary productive infection, HCMV establishes a life-long latent infection, from which it can reactivate years later to produce new, infectious virus. Despite the presence of a ...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v4112448

    authors: McSharry BP,Avdic S,Slobedman B

    更新日期:2012-10-25 00:00:00

  • High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication.

    abstract::Interferon (IFN) regulatory factor 3 (IRF3) is the key transcription factor for the induction of IFN and antiviral genes. The absence of antiviral genes in IRF3 deficiency leads to susceptibility to a wide range of viral infections. Previously, we uncovered a function for nontranscriptional IRF3 (nt-IRF3), RLR (RIG-I-...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12040442

    authors: Glanz A,Chawla K,Fabry S,Subramanian G,Garcia J,Jay B,Ciricillo J,Chakravarti R,Taylor RT,Chattopadhyay S

    更新日期:2020-04-14 00:00:00

  • Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing.

    abstract::The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. Intracellular expression of P triggers SOS-independent cellular filamenta...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v8060172

    authors: Hayes S,Wang W,Rajamanickam K,Chu A,Banerjee A,Hayes C

    更新日期:2016-06-22 00:00:00

  • Requirements within the Ebola Viral Glycoprotein for Tetherin Antagonism.

    abstract::Tetherin is an interferon-induced, intrinsic cellular response factor that blocks release of numerous viruses, including Ebola virus, from infected cells. As with many viruses targeted by host factors, Ebola virus employs a tetherin antagonist, the viral glycoprotein (EboGP), to counteract restriction and promote viru...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v7102888

    authors: Vande Burgt NH,Kaletsky RL,Bates P

    更新日期:2015-10-26 00:00:00

  • Zoonotic Hepatitis E Virus: Classification, Animal Reservoirs and Transmission Routes.

    abstract::During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of autochthonous hepatitis E in Western countries has increased as well, raising the question of what role these possible animal reservoirs play in human infections. The a...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v8100270

    authors: Doceul V,Bagdassarian E,Demange A,Pavio N

    更新日期:2016-10-03 00:00:00

  • n-3 Polyunsaturated Fatty Acids Impede the TCR Mobility and the TCR-pMHC Interaction of Anti-Viral CD8+ T Cells.

    abstract::The immune-suppressive effects of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) on T cells have been observed via multiple in vitro and in vivo models. However, the precise mechanism that causes these effects is still undefined. In this study, we investigated whether n-3 PUFAs regulated T cell receptor (TCR) and p...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v12060639

    authors: Lim Y,Kim S,Kim S,Kim DI,Kang KW,Hong SH,Lee SM,Koh HR,Seo YJ

    更新日期:2020-06-12 00:00:00

  • A hypothesis for bacteriophage DNA packaging motors.

    abstract::The hypothesis is presented that bacteriophage DNA packaging motors have a cycle comprised of bind/release thermal ratcheting with release-associated DNA pushing via ATP-dependent protein folding. The proposed protein folding occurs in crystallographically observed peptide segments that project into an axial channel o...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v2091821

    authors: Serwer P

    更新日期:2010-09-01 00:00:00

  • Molecular signatures of hepatitis C virus (HCV)-induced type II mixed cryoglobulinemia (MCII).

    abstract::The role of hepatitis C virus (HCV) infection in the induction of type II mixed cryoglobulinemia (MCII) and the possible establishment of related lymphoproliferative disorders, such as B-cell non-Hodgkin lymphoma (B-NHL), is well ascertained. However, the molecular pathways involved and the factors predisposing to th...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v4112924

    authors: Sautto G,Mancini N,Clementi M,Burioni R

    更新日期:2012-11-08 00:00:00

  • Two Different Strains of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) in North and South Osaka by Phylogenetic Analysis of Evolutionary Lineage: Evidence for Independent SFTSV Transmission.

    abstract::Severe fever with thrombocytopenia syndrome (SFTS) is a novel tick-borne infectious disease, therefore, the information on the whole genome of the SFTS virus (SFTSV) is still limited. This study demonstrates a nearly whole genome of the SFTSV identified in Osaka in 2017 and 2018 by next-generation sequencing (NGS). Th...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v13020177

    authors: Ikemori R,Aoyama I,Sasaki T,Takabayashi H,Morisada K,Kinoshita M,Ikuta K,Yumisashi T,Motomura K

    更新日期:2021-01-25 00:00:00

  • Application of CRISPR/Cas9 Gene Editing System on MDV-1 Genome for the Study of Gene Function.

    abstract::Marek's disease virus (MDV) is a member of alphaherpesviruses associated with Marek's disease, a highly contagious neoplastic disease in chickens. Complete sequencing of the viral genome and recombineering techniques using infectious bacterial artificial chromosome (BAC) clones of Marek's disease virus genome have ide...

    journal_title:Viruses

    pub_type: 杂志文章

    doi:10.3390/v10060279

    authors: Zhang Y,Tang N,Sadigh Y,Baigent S,Shen Z,Nair V,Yao Y

    更新日期:2018-05-24 00:00:00

  • Viral RNA Silencing Suppression: The Enigma of Bunyavirus NSs Proteins.

    abstract::The Bunyaviridae is a family of arboviruses including both plant- and vertebrate-infecting representatives. The Tospovirus genus accommodates plant-infecting bunyaviruses, which not only replicate in their plant host, but also in their insect thrips vector during persistent propagative transmission. For this reason, t...

    journal_title:Viruses

    pub_type: 杂志文章,评审

    doi:10.3390/v8070208

    authors: Hedil M,Kormelink R

    更新日期:2016-07-23 00:00:00