The Characterization of Immunoprotection Induced by a cDNA Clone Derived from the Attenuated Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 Strain.

abstract：:Beyond acute infections, group B coxsackieviruses (CVB) are also reported to play a role in the development of chronic diseases, like type 1 diabetes. The viral pathogenesis mainly relies on the interplay between the viruses and innate immune response in genetically-susceptible individuals. We investigated the interac...

journal_title：Viruses

authors： Alidjinou EK,Sané F,Trauet J,Copin MC,Hober D

更新日期：2015-11-24 00:00:00

abstract：:The Pneumoviridae family includes human metapneumovirus (HMPV) and human orthopneumovirus, which is also known as a respiratory syncytial virus (HRSV). These are large enveloped, negative single-strand RNA viruses. HMPV and HRSV are the human members, which commonly infect children. HMPV, which was discovered in 2001,...

journal_title：Viruses

authors： Diab M,Schmiedel D,Seidel E,Bacharach E,Mandelboim O

更新日期：2020-07-20 00:00:00

abstract：:It has been recently reported, using in vitro studies, that the herpes simplex virus 1 (HSV-1) encoded envelope glycoprotein B (gB1) interacts with cell surface toll-like receptor 2 (TLR2) and induces the secretion of interleukin-8 (IL8), a representative marker of inflammatory cytokine activation. The purpose of this...

journal_title：Viruses

authors： Marino A,Pergolizzi S,Cimino F,Lauriano ER,Speciale A,D'Angelo V,Sicurella M,Argnani R,Manservigi R,Marconi P

更新日期：2019-09-04 00:00:00

abstract：:The world's first natural avian-origin H6N1 influenza A virus infection case in dogs was confirmed in Taiwan in 2014. The H6N1 virus in chickens has been endemic in Taiwan since 1972. Whether the dog H6N1 virus has interspecies transmission potential is the key issue we aim to understand. Following one virus passage i...

journal_title：Viruses

authors： Tsai SK,Shih CH,Chang HW,Teng KH,Hsu WE,Lin HJ,Lin HY,Huang CH,Chen HW,Wang LC

更新日期：2020-06-30 00:00:00

abstract：:The development of effective yet nontoxic strategies to target the latent human immunodeficiency virus-1 (HIV-1) reservoir in antiretroviral therapy (ART)-suppressed individuals poses a critical barrier to a functional cure. The 'kick and kill' approach to HIV eradication entails proviral reactivation during ART, coup...

journal_title：Viruses

authors： Kristoff J,Rinaldo CR,Mailliard RB

更新日期：2019-12-28 00:00:00

abstract：:There is an epidemic of obesity starting about 1980 in both developed and undeveloped countries definitely associated with multiple etiologies. About 670 million people worldwide are obese. The incidence of obesity has increased in all age groups, including children. Obesity causes numerous diseases and the interactio...

journal_title：Viruses

authors： Ponterio E,Gnessi L

更新日期：2015-07-08 00:00:00

abstract：:To further understanding of the structure and morphology of the Orthohantavirus, family Hantaviridae, we have employed cryo-electron microscopy (cryo-EM) for three New World hantaviruses: Andes (ANDV), Sin Nombre (SNV), and Black Creek Canal (BCCV). Building upon our prior cryo-EM and cryo-tomography study of the Old ...

journal_title：Viruses

authors： Parvate A,Williams EP,Taylor MK,Chu YK,Lanman J,Saphire EO,Jonsson CB

更新日期：2019-09-16 00:00:00

abstract：:An equine parvovirus-hepatitis (EqPV-H) has been recently identified in association with equine serum hepatitis, also known as Theiler's disease. This disease was first described by Arnold Theiler in 1918 and is often observed after applications with blood products in equines. So far, the virus has only been described...

journal_title：Viruses

authors： Meister TL,Tegtmeyer B,Postel A,Cavalleri JV,Todt D,Stang A,Steinmann E

更新日期：2019-05-21 00:00:00

abstract：:Retroviruses are well known pathogens of mammals, birds and fish. Their potential to induce cancer in chickens was already described almost 100 years ago and murine retroviruses have been a subject of study for 50 years. The first human retroviruses, HTLV and HIV, were discovered more than 30 years ago, surprising res...

journal_title：Viruses

authors： Hohn O,Bannert N

更新日期：2011-08-01 00:00:00

abstract：:Viral CD8 T-cell epitopes, represented by viral peptides bound to major histocompatibility complex class-I (MHC-I) glycoproteins, are often identified by "reverse immunology", a strategy not requiring biochemical and structural knowledge of the actual viral protein from which they are derived by antigen processing. In...

journal_title：Viruses

authors： Fink A,Büttner JK,Thomas D,Holtappels R,Reddehase MJ,Lemmermann NA

更新日期：2014-02-14 00:00:00

abstract：:Phage display has become an established, widely used method for selection of peptides, antibodies or alternative scaffolds. The use of phage display for the selection of antigens from genomic or cDNA libraries of pathogens which is an alternative to the classical way of identifying immunogenic proteins is not well-kno...

journal_title：Viruses

authors： Kügler J,Zantow J,Meyer T,Hust M

更新日期：2013-10-16 00:00:00

abstract：:Pestiviruses, which include economically important animal pathogens such as bovine viral diarrhea virus and classical swine fever virus, possess three envelope glycoproteins, namely Erns, E1, and E2. This article discusses the structures and functions of these glycoproteins and their effects on viral pathogenicity in ...

journal_title：Viruses

authors： Wang FI,Deng MC,Huang YL,Chang CY

更新日期：2015-06-29 00:00:00

abstract：:Dengue is a worldwide problem characterized by a multifactorial pathogenesis. Considering the viral components, it is known that high viremia or high levels of the secreted nonstructural protein 1 (NS1) may be associated with a more severe disease. We aimed to characterize the NS1 antigenemia and viremia in dengue fat...

journal_title：Viruses

authors： Nunes PCG,Nogueira RMR,Heringer M,Chouin-Carneiro T,Damasceno Dos Santos Rodrigues C,de Filippis AMB,Lima MDRQ,Dos Santos FB

更新日期：2018-06-14 00:00:00

abstract：:Monoderm bacteria possess a cell envelope made of a cytoplasmic membrane and a cell wall, whereas diderm bacteria have and extra lipid layer, the outer membrane, covering the cell wall. Both cell types can also produce extracellular protective coats composed of polymeric substances like, for example, polysaccharidic c...

journal_title：Viruses

authors： Fernandes S,São-José C

更新日期：2018-07-27 00:00:00

abstract：:Streptococcus thermophilus is considered one of the most important species for the dairy industry. Due to their diffusion in dairy environments, bacteriophages can represent a threat to this widely used bacterial species. Despite the presence of a CRISPR-Cas system in the S. thermophilus genome, some lysogenic strains...

journal_title：Viruses

authors： da Silva Duarte V,Giaretta S,Campanaro S,Treu L,Armani A,Tarrah A,Oliveira de Paula S,Giacomini A,Corich V

更新日期：2018-12-22 00:00:00

abstract：:Rabies is a highly fatal zoonotic disease which is primarily caused by rabies virus (RABV) although other members of the genus Lyssavirus can cause rabies as well. As yet, 14 serologically and genetically diverse lyssaviruses have been identified, mostly in bats. To assess the quality of rabies vaccines and immunoglob...

journal_title：Viruses

authors： Moeschler S,Locher S,Conzelmann KK,Krämer B,Zimmer G

更新日期：2016-09-16 00:00:00

abstract：:Deoxynucleoside triphosphate (dNTP) molecules are essential for the replication and maintenance of genomic information in both cells and a variety of viral pathogens. While the process of dNTP biosynthesis by cellular enzymes, such as ribonucleotide reductase (RNR) and thymidine kinase (TK), has been extensively inves...

journal_title：Viruses

authors： Coggins SA,Mahboubi B,Schinazi RF,Kim B

更新日期：2020-03-31 00:00:00

abstract：:The family Totiviridae currently contains five genera Totivirus, Victorivirus, Leishmavirus, Trichomonasvirus, and Giardiavirus. Members in this family generally have a set of two-open reading frame (ORF) elements in their genome with the 5'-proximal ORF (ORF1) encoding a capsid protein (CP) and the 3'-proximal one (O...

journal_title：Viruses

authors： Jamal A,Sato Y,Shahi S,Shamsi W,Kondo H,Suzuki N

更新日期：2019-06-25 00:00:00

abstract：:Three dsRNAs, in sizes of approximately 2.5⁻5 kbp, were detected in the plant pathogenic fungus Nigrospora oryzae strain CS-7.5-4. Genomic analysis showed that the 5.0 kb dsRNA was a victorivirus named as Nigrospora oryzae victorivirus 2 (NoRV2). The genome of NoRV2 was 5166 bp in length containing two overlapping ope...

journal_title：Viruses

authors： Liu H,Liu R,Li CX,Wang H,Zhu HJ,Gao BD,Zhou Q,Zhong J

更新日期：2019-01-19 00:00:00

abstract：:Sandfly-borne phleboviruses pathogenic to humans, such as Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV), are endemic in the Mediterranean region. In France, several autochthonous cases of TOSV infection have been described, causing either meningitis or encephalitis. The aim of the present study was to i...

journal_title：Viruses

authors： Masse S,Ayhan N,Capai L,Bosseur F,de Lamballerie X,Charrel R,Falchi A

更新日期：2019-09-04 00:00:00

abstract：:Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS. Tula virus (TULV) is also widely distributed in Europe, but there is little knowledge about the pathogenicity of TULV for humans, as r...

journal_title：Viruses

authors： Bourquain D,Bodenstein C,Schürer S,Schaade L

更新日期：2019-09-14 00:00:00

abstract：:Mechanistic models are critical for our understanding of both within-host dynamics (i.e., pathogen replication and immune system processes) and among-host dynamics (i.e., transmission). Within-host models, however, are not often fit to experimental data, which can serve as a robust method of hypothesis testing and hyp...

journal_title：Viruses

authors： Mihaljevic JR,Greer AL,Brunner JL

更新日期：2019-04-27 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the etiological agent for a serious lower respiratory tract disease responsible for close to 200,000 annual deaths worldwide. The first infection is generally most severe, while re-infections usually associate with a milder disease. This observation and the finding that re-infecti...

journal_title：Viruses

authors： Rudraraju R,Jones BG,Sealy R,Surman SL,Hurwitz JL

更新日期：2013-02-05 00:00:00

abstract：:Porcine epidemic diarrhea (PED) has re-emerged in recent years and has already caused huge economic losses to the porcine industry all over the world. Therefore, it is urgent for us to find out efficient ways to prevent and control this disease. In this study, the antiviral activity of a cationic amphibian antimicrobi...

journal_title：Viruses

authors： Guo N,Zhang B,Hu H,Ye S,Chen F,Li Z,Chen P,Wang C,He Q

更新日期：2018-09-18 00:00:00

abstract：:Many blood-feeding arthropods are known vectors of viruses that are a source of unprecedented global health concern. Mosquitoes are an integral part of these arthropod vectors. Advancements in next-generation sequencing and bioinformatics has expanded our knowledge on the richness of viruses harbored by arthropods. In...

journal_title：Viruses

authors： Atoni E,Wang Y,Karungu S,Waruhiu C,Zohaib A,Obanda V,Agwanda B,Mutua M,Xia H,Yuan Z

更新日期：2018-01-12 00:00:00

abstract：:Samples of two Ageratum conyzoides, one Sonchus oleraceus and one turnip (Brassica rapa var. rapa) exhibiting virus-like symptoms were collected from Pakistan and Nepal. Full-length begomovirus clones were obtained from the four plant samples and betasatellite clones from three of these. The begomovirus sequences were...

journal_title：Viruses

authors： Tahir M,Amin I,Haider MS,Mansoor S,Briddon RW

更新日期：2015-02-10 00:00:00

abstract：:As countries with endemic canine rabies progress towards elimination by 2030, it will become necessary to employ techniques to help plan, monitor, and confirm canine rabies elimination. Sequencing can provide critical information to inform control and vaccination strategies by identifying genetically distinct virus va...

journal_title：Viruses

authors： Gigante CM,Yale G,Condori RE,Costa NC,Long NV,Minh PQ,Chuong VD,Tho ND,Thanh NT,Thin NX,Hanh NTH,Wambura G,Ade F,Mito O,Chuchu V,Muturi M,Mwatondo A,Hampson K,Thumbi SM,Thomae BG,de Paz VH,Meneses S,Munyua P,

更新日期：2020-11-04 00:00:00

abstract：:Kaposi's sarcoma associated herpesvirus (KSHV), like other human herpes viruses, establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic phases. The latent phase is characterized by the persistence of viral episomes in a highly ordered chromatin structure and with the expression of ...

journal_title：Viruses

authors： Uppal T,Banerjee S,Sun Z,Verma SC,Robertson ES

更新日期：2014-12-11 00:00:00

abstract：:The degree of antigenic drift in swine influenza A viruses (swIAV) has historically been regarded as minimal compared to that of human influenza A virus strains. However, as surveillance activities on swIAV have increased, more isolates have been characterized, revealing a high level of genetic and antigenic differenc...

journal_title：Viruses

authors： Ryt-Hansen P,Pedersen AG,Larsen I,Kristensen CS,Krog JS,Wacheck S,Larsen LE

更新日期：2020-02-23 00:00:00

abstract：:Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense RNA genome that can cause serious illness in humans and animals. The 11 kb 5' capped RNA genome consists of a single open reading frame (ORF), and is flanked by 5' and 3' untranslated regions (UTR). The ORF is a polyprotein that ...

journal_title：Viruses

authors： Ng WC,Soto-Acosta R,Bradrick SS,Garcia-Blanco MA,Ooi EE

更新日期：2017-06-06 00:00:00