MERS-CoV: Understanding the Latest Human Coronavirus Threat.


:Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man died as a result of renal and respiratory failure after admission to a hospital in Jeddah, Saudi Arabia. The aetiological agent was eventually identified as a coronavirus and designated Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV has now been reported in more than 27 countries across the Middle East, Europe, North Africa and Asia. As of July 2017, 2040 MERS-CoV laboratory confirmed cases, resulting in 712 deaths, were reported globally, with a majority of these cases from the Arabian Peninsula. This review summarises the current understanding of MERS-CoV, with special reference to the (i) genome structure; (ii) clinical features; (iii) diagnosis of infection; and (iv) treatment and vaccine development.






Chafekar A,Fielding BC




Has Abstract


2018-02-24 00:00:00










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  • New Markers in Monitoring the Reactivation of Hepatitis B Virus Infection in Immunocompromised Hosts.

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    authors: Svicher V,Salpini R,Malagnino V,Piermatteo L,Alkhatib M,Cerva C,Sarmati L

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    authors: Ryt-Hansen P,Pedersen AG,Larsen I,Kristensen CS,Krog JS,Wacheck S,Larsen LE

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  • Therapeutic Use of Native and Recombinant Enteroviruses.

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    authors: Ylä-Pelto J,Tripathi L,Susi P

    更新日期:2016-02-23 00:00:00

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    authors: Wu X,Zhai X,Lai Y,Zuo L,Zhang Y,Mei X,Xiang R,Kang Z,Zhou L,Wang H

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    authors: Johnson N,Aréchiga-Ceballos N,Aguilar-Setien A

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    authors: Fink A,Büttner JK,Thomas D,Holtappels R,Reddehase MJ,Lemmermann NA

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    authors: Brinton MA

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    authors: Zhang Y,Tang N,Sadigh Y,Baigent S,Shen Z,Nair V,Yao Y

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    authors: Zuo J,Rowe M

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    authors: Michiels R,Van Mael E,Quinet C,Adjadj NR,Cay AB,De Regge N

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    authors: Piedade GJ,Wesdorp EM,Montenegro-Borbolla E,Maat DS,Brussaard CPD

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    authors: Kanda T,Sasaki R,Masuzaki R,Matsumoto N,Ogawa M,Moriyama M

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    pub_type: 杂志文章


    authors: Wei R,Chen G,Algehainy N,Zeng C,Liu C,Liu H,Liu W,Stacey D,Zhou A

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    pub_type: 杂志文章


    authors: Jacquat AG,Theumer MG,Cañizares MC,Debat HJ,Iglesias J,García Pedrajas MD,Dambolena JS

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    pub_type: 杂志文章


    authors: Orrú CD,Hughson AG,Groveman BR,Campbell KJ,Anson KJ,Manca M,Kraus A,Caughey B

    更新日期:2016-05-23 00:00:00

  • Organization, Function, and Therapeutic Targeting of the Morbillivirus RNA-Dependent RNA Polymerase Complex.

    abstract::The morbillivirus genus comprises major human and animal pathogens, including the highly contagious measles virus. Morbilliviruses feature single stranded negative sense RNA genomes that are wrapped by a plasma membrane-derived lipid envelope. Genomes are encapsidated by the viral nucleocapsid protein forming ribonucl...


    pub_type: 杂志文章,评审


    authors: Sourimant J,Plemper RK

    更新日期:2016-09-10 00:00:00

  • Characterization of a Novel Thermobifida fusca Bacteriophage P318.

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    pub_type: 杂志文章


    authors: Cheepudom J,Lin TL,Lee CC,Meng M

    更新日期:2019-11-08 00:00:00