Abstract：
:Dengue virus (DENV) is the most widespread arthropod-borne virus, with the number and severity of outbreaks increasing worldwide in recent decades. Dengue is caused by genetically distinct serotypes, DENV-1-4. Here, we present data on DENV-1, isolated from patients with dengue fever during an outbreak in Senegal and Mali (Western Africa) in 2015-2019, that were analyzed by sequencing the envelope (E) gene. The emergence and the dynamics of DENV-1 in Western Africa were inferred by using maximum likelihood and Bayesian methods. The DENV-1 grouped into a monophyletic cluster that was closely related to those from Southeast Asia. The virus appears to have been introduced directly into Medina Gounass (Suburb of Dakar), Senegal (location probability = 0.301, posterior = 0.76). The introduction of the virus in Senegal occurred around 2014 (95% HPD = 2012.88-2014.84), and subsequently, the virus moved to regions within Senegal (e.g., Louga and Fatick), causing intense outbreaks in the subsequent years. The virus appears to have been introduced in Mali (a neighboring country) after its introduction in Senegal. In conclusion, we present evidence that the outbreak caused by DENV-1 in urban environments in Senegal and Mali after 2015 was caused by a single viral introduction from Asia.
journal_name
Virusesjournal_title
Virusesauthors
Dieng I,Cunha M,Diagne MM,Sembène PM,Zanotto PMA,Faye O,Faye O,Sall AAdoi
10.3390/v13010057subject
Has Abstractpub_date
2021-01-04 00:00:00issue
1issn
1999-4915pii
v13010057journal_volume
13pub_type
杂志文章相关文献
Viruses-Basel文献大全abstract：:Developments of genome amplification techniques have rapidly expanded the family of human polyomaviruses (PyV). Following infection early in life, PyV persist in their hosts and are generally of no clinical consequence. High-level replication of PyV can occur in patients under immunosuppressive or immunomodulatory the...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v8100292
更新日期：2016-10-22 00:00:00
abstract：:To further understanding of the structure and morphology of the Orthohantavirus, family Hantaviridae, we have employed cryo-electron microscopy (cryo-EM) for three New World hantaviruses: Andes (ANDV), Sin Nombre (SNV), and Black Creek Canal (BCCV). Building upon our prior cryo-EM and cryo-tomography study of the Old ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11090862
更新日期：2019-09-16 00:00:00
abstract：:Seoul virus (SEOV) is a zoonotic orthohantavirus carried by black and brown rats, and can cause hemorrhagic fever with renal syndrome in humans. Human cases of SEOV virus infection have most recently been reported in the USA, United Kingdom, France and the Netherlands and were primarily associated with contact with pe...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11060531
更新日期：2019-06-07 00:00:00
abstract：:Canine distemper virus (CDV) is a member of the genus morbillivirus, which is known to cause a variety of disorders in dogs including demyelinating leukoencephalitis (CDV-DL). In recent years, substantial progress in understanding the pathogenetic mechanisms of CDV-DL has been made. In vivo and in vitro investigations...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v6072571
更新日期：2014-07-02 00:00:00
abstract：:Avian infectious bronchitis has caused huge economic losses in the poultry industry. Previous studies have reported that infectious bronchitis virus (IBV) infection can produce cytopathic effects (CPE) and apoptosis in some mammalian cells and primary cells. However, there is little research on IBV-induced immune cell...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v9080198
更新日期：2017-07-26 00:00:00
abstract：:Viroids are small non-capsidated non-coding RNA replicons that utilize host factors for efficient propagation and spread through the entire plant. They can incite specific disease symptoms in susceptible plants. To better understand viroid-plant interactions, we employed microarray analysis to observe the changes of g...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10050257
更新日期：2018-05-15 00:00:00
abstract：:Nasopharyngeal cancer (NPC) is associated with Epstein Barr virus (EBV) infection. However different viral strains have been implicated in NPC worldwide. This study aimed to detect and characterize EBV in patients diagnosed with NPC in Ghana. A total of 55 patients diagnosed with NPC by CT scan and endoscopy were age-...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12070766
更新日期：2020-07-16 00:00:00
abstract：:We previously characterized a carbohydrate binding protein, Gp047, derived from lytic Campylobacter phage NCTC 12673, as a promising diagnostic tool for the identification of Campylobacter jejuni and Campylobacter coli. We also demonstrated that this protein binds specifically to acetamidino-modified pseudaminic acid ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v7122964
更新日期：2015-12-16 00:00:00
abstract：:Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense RNA genome that can cause serious illness in humans and animals. The 11 kb 5' capped RNA genome consists of a single open reading frame (ORF), and is flanked by 5' and 3' untranslated regions (UTR). The ORF is a polyprotein that ...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9060137
更新日期：2017-06-06 00:00:00
abstract：:Rabies is a viral infection that targets the nervous system, specifically neurons. The clinical manifestations of the disease are dramatic and their outcome fatal; paradoxically, conventional histopathological descriptions reveal only subtle changes in the affected nervous tissue. Some researchers have considered that...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10030112
更新日期：2018-03-06 00:00:00
abstract：:The objective of this study was to evaluate the effects of A3R phage and Staphylococcus aureus lysate obtained after phage infection on neutrophil degranulation. The exocytosis of primary and secondary granules from neutrophils was investigated in vitro in whole blood specimens by flow cytometry based on the expressio...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v9020036
更新日期：2017-02-21 00:00:00
abstract：:Viroids are small, non-coding, circular RNA molecules that infect plants. Different hypotheses for their evolutionary origin have been put forward, such as an early emergence in a precellular RNA World or several de novo independent evolutionary origins in plants. Here, we discuss the plausibility of de novo emergence...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11050425
更新日期：2019-05-09 00:00:00
abstract：:Exosomes are membrane-enclosed vesicles actively released into the extracellular space, whose content reflect the physiological/pathological state of the cells they originate from. These vesicles participate in cell-to-cell communication and transfer of biologically active proteins, lipids, and RNAs. Their role in vir...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v7062770
更新日期：2015-06-19 00:00:00
abstract：:Effects of elevated pCO₂ on Emiliania huxleyi genetic diversity and the viruses that infect E. huxleyi (EhVs) have been investigated in large volume enclosures in a Norwegian fjord. Triplicate enclosures were bubbled with air enriched with CO₂ to 760 ppmv whilst the other three enclosures were bubbled with air at ambi...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v9030041
更新日期：2017-03-08 00:00:00
abstract：:The Protoparvovirus (PtPV) genus of the Parvoviridae family of viruses includes important animal pathogens and reference molecular models for the entire family. Some virus members of the PtPV genus have arisen as promising tools to treat tumoral processes, as they exhibit marked oncotropism and oncolytic activities wh...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9110313
更新日期：2017-10-26 00:00:00
abstract：:Persistent circulative transmission of plant viruses involves complex interactions between the transmitted virus and its insect vector. Several studies have shown that insect vector proteins are involved in the passage and the transmission of the virus. Interestingly, proteins expressed by bacterial endosymbionts that...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v5061516
更新日期：2013-06-19 00:00:00
abstract：:The immune-suppressive effects of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) on T cells have been observed via multiple in vitro and in vivo models. However, the precise mechanism that causes these effects is still undefined. In this study, we investigated whether n-3 PUFAs regulated T cell receptor (TCR) and p...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12060639
更新日期：2020-06-12 00:00:00
abstract：:Tetherin is an interferon-induced, intrinsic cellular response factor that blocks release of numerous viruses, including Ebola virus, from infected cells. As with many viruses targeted by host factors, Ebola virus employs a tetherin antagonist, the viral glycoprotein (EboGP), to counteract restriction and promote viru...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v7102888
更新日期：2015-10-26 00:00:00
abstract：:A Chikungunya virus (CHIKV) outbreak in Italy in 2007 spread to include the islands of the Caribbean and most of the Americas and still circulates in Europe and Africa. Florida being close in distance to the Caribbean islands experienced a CHIKV outbreak in 2014 and continues to have a few travel-related cases each ye...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12080823
更新日期：2020-07-29 00:00:00
abstract：:The genomes of polyomaviruses are characterized by their tripartite organization with an early region, a late region and a noncoding control region (NCCR). The early region encodes proteins involved in replication and transcription of the viral genome, while expression of the late region generates the capsid proteins....
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v12121406
更新日期：2020-12-07 00:00:00
abstract：:Iminosugars that are competitive inhibitors of endoplasmic reticulum (ER) α-glucosidases have been demonstrated to have antiviral activity against a diverse set of viruses. A novel iminosugar, UV-4B, has recently been shown to provide protection against lethal infections with dengue and influenza A (H1N1) viruses in m...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v8030071
更新日期：2016-03-07 00:00:00
abstract：:Viral encephalitis causes acute inflammation of the brain parenchyma and is a significant cause of human morbidity and mortality. Although Herpes Simplex encephalitis is the most frequent known cause of fatal sporadic encephalitis in humans, an increasingly wide range of viruses and other microbial pathogens are impli...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v9060138
更新日期：2017-06-06 00:00:00
abstract：:The development of high-throughput technologies allows for evaluating gene expression at the whole-genome level. Together with proteomic and metabolomic studies, these analyses have resulted in the identification of plant genes whose function or expression is altered as a consequence of pathogen attacks. Members of th...
journal_title：Viruses
pub_type： 杂志文章,评审
doi：10.3390/v5030998
更新日期：2013-03-22 00:00:00
abstract：:Emerging viruses have caused concerns about pollinator population declines, as multi-host RNA viruses may pose a health threat to pollinators and associated arthropods. In order to understand the ecology and impact these viruses have, we studied their host range and determined to what extent host and spatial variation...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12030358
更新日期：2020-03-24 00:00:00
abstract：:Zika virus (ZIKV) is a vertically and sexually transmissible virus resulting in severe congenital malformation. The goal of this study was to develop an ovine model of ZIKV infection. Between 28-35 days gestation (DG), four pregnant animals were infected with two doses of 6 × 106 PFU of ZIKV; four control animals rece...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v11090795
更新日期：2019-08-29 00:00:00
abstract：:Equine influenza, caused by the H3N8 subtype, is a highly contagious respiratory disease affecting equid populations worldwide and has led to serious epidemics and transboundary pandemics. This study describes the phylogenetic characterization and replication kinetics of recently-isolated H3N8 virus from a nasal swab ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v10010031
更新日期：2018-01-11 00:00:00
abstract：:Laboratories throughout the world that perform work with Risk Group 4 Pathogens generally adopt one of two approaches within BSL-4 environments: either the use of positive pressure air-fed suits or using Class III microbiological safety cabinets and isolators for animal work. Within the UK at present, all laboratories...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v4081202
更新日期：2012-08-01 00:00:00
abstract：:HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we found that exosomes, a type of extracellular vesicle (EV), from uninfected cells activate the transcription of HIV-1 ...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12060665
更新日期：2020-06-19 00:00:00
abstract：:The Australasian Virology Society (AVS) aims to promote, support and advocate for the discipline of virology in the Australasian region. The society was incorporated in 2011 after 10 years operating as the Australian Virology Group (AVG) founded in 2001, coinciding with the inaugural biennial scientific meeting. AVS c...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v12060621
更新日期：2020-06-06 00:00:00
abstract：:Different lines of evidence support an association between Epstein-Barr virus (EBV) and gastric cancer (GC). The main understood risk factor to develop GC is infection by Helicobacter pylori (H. pylori), which triggers a local inflammatory response critical for progression from gastritis to GC. The role of EBV in earl...
journal_title：Viruses
pub_type： 杂志文章
doi：10.3390/v6010301
更新日期：2014-01-20 00:00:00
