Poxviruses in bats … so what?

Abstract:

:Poxviruses are important pathogens of man and numerous domestic and wild animal species. Cross species (including zoonotic) poxvirus infections can have drastic consequences for the recipient host. Bats are a diverse order of mammals known to carry lethal viral zoonoses such as Rabies, Hendra, Nipah, and SARS. Consequent targeted research is revealing bats to be infected with a rich diversity of novel viruses. Poxviruses were recently identified in bats and the settings in which they were found were dramatically different. Here, we review the natural history of poxviruses in bats and highlight the relationship of the viruses to each other and their context in the Poxviridae family. In addition to considering the zoonotic potential of these viruses, we reflect on the broader implications of these findings. Specifically, the potential to explore and exploit this newfound relationship to study coevolution and cross species transmission together with fundamental aspects of poxvirus host tropism as well as bat virology and immunology.

journal_name

Viruses

journal_title

Viruses

authors

Baker KS,Murcia PR

doi

10.3390/v6041564

subject

Has Abstract

pub_date

2014-04-03 00:00:00

pages

1564-77

issue

4

issn

1999-4915

pii

v6041564

journal_volume

6

pub_type

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