Respiratory Epithelial Cells Respond to Lactobacillus plantarum but Provide No Cross-Protection against Virus-Induced Inflammation.

abstract：:Enteroviruses are a group of over 250 naked icosahedral virus serotypes that have been associated with clinical conditions that range from intrauterine enterovirus transmission withfataloutcome through encephalitis and meningitis, to paralysis. Classically, enterovirus detection was done by assaying for the developmen...

journal_title：Viruses

authors： Faleye TO,Adewumi MO,Adeniji JA

更新日期：2016-01-12 00:00:00

abstract：:Non-human primates (NHP) are the only animal model suitable to evaluate the protection efficacy of HIV-1 vaccines. It is important to understand how and when neutralizing antibodies (nAbs) with specificities similar to those of human broadly neutralizing antibodies (bnAbs) develop in NHPs. To address these questions, ...

journal_title：Viruses

authors： Gao N,Gai Y,Meng L,Wang C,Zhang X,Wang W,Qin C,Yu X,Gao F

更新日期：2020-01-31 00:00:00

abstract：:The genomes of polyomaviruses are characterized by their tripartite organization with an early region, a late region and a noncoding control region (NCCR). The early region encodes proteins involved in replication and transcription of the viral genome, while expression of the late region generates the capsid proteins....

journal_title：Viruses

authors： Moens U,Prezioso C,Pietropaolo V

更新日期：2020-12-07 00:00:00

abstract：:The development of oncolytic viruses has led to an emerging new class of cancer therapeutics. Although the safety profile has been encouraging, the transition of oncolytic viruses to the clinical setting has been a slow process due to modifications. Therefore, a new generation of more potent oncolytic viruses needs to...

journal_title：Viruses

authors： Yuan M,Webb E,Lemoine NR,Wang Y

更新日期：2016-03-07 00:00:00

abstract：:The most highly expressed protein during the productive phase of the human papillomavirus (HPV) life cycle is E1^E4. Its full role during infection remains to be established. HPV E1^E4 is expressed during both the early and late stages of the virus life cycle and contributes to viral genome amplification. In an attemp...

journal_title：Viruses

authors： Biryukov J,Myers JC,McLaughlin-Drubin ME,Griffin HM,Milici J,Doorbar J,Meyers C

更新日期：2017-12-19 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is an important cancer-causing human retrovirus that has infected approximately 15 million individuals worldwide. Many aspects of HTLV-1 replication, including virus particle structure and assembly, are poorly understood. Group-specific antigen (Gag) proteins labeled at the ...

journal_title：Viruses

authors： Maldonado JO,Angert I,Cao S,Berk S,Zhang W,Mueller JD,Mansky LM

更新日期：2017-07-19 00:00:00

abstract：:Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis C infection associates with lipid and lipoprotein metabolism disorders such as hepatic steatosis, hypobetalipoproteinemia, and hypocholesterolemia. Furthermore,...

journal_title：Viruses

authors： Felmlee DJ,Hafirassou ML,Lefevre M,Baumert TF,Schuster C

更新日期：2013-05-23 00:00:00

abstract：:We are currently facing a pandemic of COVID-19, caused by a spillover from an animal-originating coronavirus to humans occurring in the Wuhan region of China in December 2019. From China, the virus has spread to 188 countries and regions worldwide, reaching the Sahel region on March 2, 2020. Since whole genome sequenc...

journal_title：Viruses

authors： Kouriba B,Dürr A,Rehn A,Sangaré AK,Traoré BY,Bestehorn-Willmann MS,Ouedraogo J,Heitzer A,Sogodogo E,Maiga A,Walter MC,Zimmermann F,Wölfel R,Antwerpen MH

更新日期：2020-11-02 00:00:00

abstract：:West Nile (WNV) and Dengue (DENV) viruses are major arboviral human pathogens belonging to the genus Flavivirus. At the current time, there are no approved prophylactics (e.g., vaccines) or specific therapeutics available to prevent or treat human infections by these pathogens. Due to their minimal genome, these virus...

journal_title：Viruses

authors： Krishnan MN,Garcia-Blanco MA

更新日期：2014-02-10 00:00:00

abstract：:In this review, we describe the distribution and genetic diversity of sapoviruses detected among humans, animals and the environment in African countries. Databases were searched for studies conducted in African countries and published between Jan 2005 and Mar 2019. Only studies where RT- PCR was used for initial dete...

journal_title：Viruses

authors： Makhaola K,Moyo S,Kebaabetswe LP

更新日期：2020-04-27 00:00:00

abstract：:Human immunodeficiency virus (HIV) is a causative agent of acquired immune deficiency syndrome (AIDS). Highly active antiretroviral therapy (HAART) can slow down the replication of HIV-1, leading to an improvement in the survival of HIV-1-infected patients. However, drug toxicities and poor drug administration has led...

journal_title：Viruses

authors： Chupradit K,Moonmuang S,Nangola S,Kitidee K,Yasamut U,Mougel M,Tayapiwatana C

更新日期：2017-09-29 00:00:00

abstract：:It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and c...

journal_title：Viruses

authors： Grove J

更新日期：2014-03-19 00:00:00

abstract：:The smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae), is an economically important pest of tea in Japan. Previous work showed that a fast-killing nucleopolyhedrovirus (NPV) isolated from A. orana (AdorNPV) and a slow-killing NPV isolated from A. honmai (AdhoNPV) are both infectious to A. honmai larvae...

journal_title：Viruses

authors： Takahashi M,Nakai M,Saito Y,Sato Y,Ishijima C,Kunimi Y

更新日期：2015-03-18 00:00:00

abstract：:A novel virus from moribund European chub (Squalius cephalus) was isolated on epithelioma papulosum cyprini (EPC) cells. Transmission electron microscopic examination revealed abundant non-enveloped, hexagonal virus particles in the cytoplasm of infected EPC cells consistent with an iridovirus. Illumina MiSeq sequence...

journal_title：Viruses

authors： Halaly MA,Subramaniam K,Koda SA,Popov VL,Stone D,Way K,Waltzek TB

更新日期：2019-05-15 00:00:00

abstract：:Sandfly-borne phleboviruses pathogenic to humans, such as Toscana virus (TOSV) and Sandfly Fever Sicilian virus (SFSV), are endemic in the Mediterranean region. In France, several autochthonous cases of TOSV infection have been described, causing either meningitis or encephalitis. The aim of the present study was to i...

journal_title：Viruses

authors： Masse S,Ayhan N,Capai L,Bosseur F,de Lamballerie X,Charrel R,Falchi A

更新日期：2019-09-04 00:00:00

abstract：:Duck Tembusu virus (DTMUV) is a recently emerging pathogenic flavivirus that has resulted in a huge economic loss in the duck industry. However, no vaccine is currently available to control this pathogen. Consequently, a practical strategy to construct a vaccine against this pathogen should be determined. In this stud...

journal_title：Viruses

authors： Zou Z,Liu Z,Jin M

更新日期：2014-06-20 00:00:00

abstract：:Ringspot symptoms in European mountain ash (Sorbus aucuparia L.), fig mosaic, rose rosette, raspberry leaf blotch, pigeonpea sterility mosaic (Cajanus cajan) and High Plains disease of maize and wheat were found to be associated with viruses that share several characteristics. They all have single-stranded multipartit...

journal_title：Viruses

authors： Mielke-Ehret N,Mühlbach HP

更新日期：2012-09-01 00:00:00

abstract：:African swine fever (ASF) has become the major threat for the global swine industry. Furthermore, the epidemiological situation of African swine fever virus (ASFV) in some endemic regions of Sub-Saharan Africa is worse than ever, with multiple virus strains and genotypes currently circulating in a given area. Despite ...

journal_title：Viruses

authors： Lopez E,van Heerden J,Bosch-Camós L,Accensi F,Navas MJ,López-Monteagudo P,Argilaguet J,Gallardo C,Pina-Pedrero S,Salas ML,Salt J,Rodriguez F

更新日期：2020-12-21 00:00:00

abstract：:At present, the clinical detection method of human papillomavirus (HPV) is mainly based on the PCR method. However, this method can only be used to detect HPV DNA and HPV types, and cannot be used to accurately predict cervical cancer. HPV16 E7 is an oncoprotein selectively expressed in cervical cancers. In this study...

journal_title：Viruses

authors： Hu R,Dong Z,Zhang K,Pan G,Li C,Cui H

更新日期：2020-03-19 00:00:00

abstract：:Recently, Alves-Freitas and colleagues [...]. ...

journal_title：Viruses

authors： Bejerman N,Dietzgen RG

更新日期：2019-03-07 00:00:00

abstract：:The role of hepatitis C virus (HCV) infection in the induction of type II mixed cryoglobulinemia (MCII) and the possible establishment of related lymphoproliferative disorders, such as B-cell non-Hodgkin lymphoma (B-NHL), is well ascertained. However, the molecular pathways involved and the factors predisposing to th...

journal_title：Viruses

authors： Sautto G,Mancini N,Clementi M,Burioni R

更新日期：2012-11-08 00:00:00

abstract：:Herpesviridae comprise a large family of enveloped DNA viruses all of whom employ orthologs of the same three glycoproteins, gB, gH and gL. Additionally, herpesviruses often employ accessory proteins to bind receptors and/or bind the heterodimer gH/gL or even to determine cell tropism. Sorting out how these proteins f...

journal_title：Viruses

authors： Eisenberg RJ,Atanasiu D,Cairns TM,Gallagher JR,Krummenacher C,Cohen GH

更新日期：2012-05-01 00:00:00

abstract：:Human influenza A(H2N2) viruses emerged in 1957 and were replaced by A(H3N2) viruses in 1968. The antigenicity of human H2N2 viruses has been tested by using ferret antisera or mouse and human monoclonal antibodies. Here, we examined the antigenicity of human H2N2 viruses by using human plasma samples obtained from 50...

journal_title：Viruses

authors： Matsuzawa Y,Iwatsuki-Horimoto K,Nishimoto Y,Abe Y,Fukuyama S,Hamabata T,Okuda M,Go Y,Watanabe T,Imai M,Arai Y,Fouchier RAM,Yamayoshi S,Kawaoka Y

更新日期：2019-10-23 00:00:00

abstract：:Influenza A viruses (IAVs) are highly contagious pathogens infecting human and numerous animals. The viruses cause millions of infection cases and thousands of deaths every year, thus making IAVs a continual threat to global health. Upon IAV infection, host innate immune system is triggered and activated to restrict v...

journal_title：Viruses

authors： Zhang Y,Xu Z,Cao Y

更新日期：2020-03-29 00:00:00

abstract：:Zika virus (ZIKV) infection can cause severe congenital diseases, such as microcephaly, ocular defects and arthrogryposis in fetuses, and Guillain⁻Barré syndrome in adults. Efficacious therapeutic treatments for infected patients, as well as prophylactic treatments to prevent new infections are needed for combating ZI...

journal_title：Viruses

authors： Siddharthan V,Miao J,Van Wettere AJ,Li R,Wu H,Sullivan E,Jiao J,Hooper JW,Safronetz D,Morrey JD,Julander JG,Wang Z

更新日期：2019-01-22 00:00:00

abstract：:Type II transmembrane serine proteases (TTSPs) facilitate the spread and replication of viruses such as influenza and human coronaviruses, although it remains unclear whether TTSPs play a role in the progression of animal coronavirus infections, such as that by porcine epidemic diarrhea virus (PEDV). In this study, TT...

journal_title：Viruses

authors： Shi W,Fan W,Bai J,Tang Y,Wang L,Jiang Y,Tang L,Liu M,Cui W,Xu Y,Li Y

更新日期：2017-05-18 00:00:00

abstract：:Porcine epidemic diarrhea (PED) has re-emerged in recent years and has already caused huge economic losses to the porcine industry all over the world. Therefore, it is urgent for us to find out efficient ways to prevent and control this disease. In this study, the antiviral activity of a cationic amphibian antimicrobi...

journal_title：Viruses

authors： Guo N,Zhang B,Hu H,Ye S,Chen F,Li Z,Chen P,Wang C,He Q

更新日期：2018-09-18 00:00:00

abstract：:Dengue virus (DENV) infection has become a critically important globally prevalent infectious disease, especially in tropical and subtropical countries. Since neither currently exists, there is an urgent need for an effective vaccine to prevent, and a specific drug to treat DENV infection. Therapeutic peptides represe...

journal_title：Viruses

authors： Panya A,Sawasdee N,Songprakhon P,Tragoolpua Y,Rotarayanont S,Choowongkomon K,Yenchitsomanus PT

更新日期：2020-11-06 00:00:00

abstract：:Seoul virus (SEOV) is a zoonotic orthohantavirus carried by black and brown rats, and can cause hemorrhagic fever with renal syndrome in humans. Human cases of SEOV virus infection have most recently been reported in the USA, United Kingdom, France and the Netherlands and were primarily associated with contact with pe...

journal_title：Viruses

authors： Maas M,van Heteren M,de Vries A,Kuiken T,Hoornweg T,Veldhuis Kroeze E,Rockx B

更新日期：2019-06-07 00:00:00

abstract：:Human parechovirus (HPeV), particularly type 3 (HPeV3), is an important cause of sepsis-/meningitis-like illness in young infants. Laboratory records identified a total of ten HPeV-positive cases in Southeastern Australia between January and July 2019. The HPeV present in these cases were typed by Sanger sequencing of...

journal_title：Viruses

authors： Chamings A,Liew KC,Reid E,Athan E,Raditsis A,Vuillermin P,Yoga Y,Caly L,Druce J,Alexandersen S

更新日期：2019-10-03 00:00:00