Interferon yield and MHC antigen expression of human medulloblastoma cells and its suppression during dibutyryl cyclic AMP-induced differentiation: do medulloblastoma cells derive from bipotent neuronal and glial progenitors?

abstract：:Sulfur dioxide (SO2) is a common gas pollutant that is detrimental to many organs. Previous studies have shown that SO2 exposure is involved in neurotoxicity and increased risk of many brain disorders; however, our understanding of the mechanisms underlying SO2-induced cytotoxicity on neuronal cells remains elusive. T...

journal_title：Cellular and molecular neurobiology

authors： Guan DF,Ren PY,Hu W,Zhang YL

更新日期：2015-05-01 00:00:00

abstract：:Working memory (WM) is a highly heritable cognitive trait that is involved in many higher-level cognitive functions. In the past few years, much evidence has indicated that the reduction of dopamine activity in human brain can impair the WM system of the neuropsychiatric disorders. In this study, we hypothesized that ...

journal_title：Cellular and molecular neurobiology

authors： Gong P,Zhang H,Chi W,Ge W,Zhang K,Zheng A,Gao X,Zhang F

更新日期：2012-08-01 00:00:00

abstract：:Compound 511 (511) is specially developed for opioid addiction treatment based on the Ancient Chinese drug rehabilitation literature, and its composition has profound effects in the treatment of drug addiction in various clinical trials and animal experiments. The effect of 511 on the rewarding properties of morphine ...

journal_title：Cellular and molecular neurobiology

authors： Zhang H,Wang Q,Sun Q,Qin F,Nie D,Li Q,Gu Y,Jiang Y,Lu S,Lu Z

更新日期：2020-04-22 00:00:00

abstract：:Saturable sodium-independent taurine binding to mouse and rat brain synaptic membranes was exposed after two freezing-thawing cycles combined with Triton X-100 treatments. The amount of saturable taurine binding was fairly low but was enhanced after depletion of brain taurine. Saturable taurine binding was displaceabl...

journal_title：Cellular and molecular neurobiology

authors： Kontro P,Oja SS

更新日期：1983-06-01 00:00:00

abstract：:The insulin-like growth factor (IGF) system is linked to CNS pathological states. The functions of IGFs are modulated by a family of binding proteins termed insulin-like growth factor binding proteins (IGFBPs). Here, we demonstrate that IGFBP-6 may be associated with neuronal apoptosis in the processes of intracerebra...

journal_title：Cellular and molecular neurobiology

authors： Dai Q,Jiang P,Gu Y,Zhu L,Dai H,Yao Z,Liu H,Ma X,Duan C,Qu L

更新日期：2017-10-01 00:00:00

abstract：:The allelic variant of apolipoprotein (Apo) E4 is a known risk factor for the development of most common late onset form of Alzheimer's disease (AD). As aging is associated with reduced circulating level of gonadal steroid hormones, hormone replacement therapies have been used for the possible treatment of AD. Both es...

journal_title：Cellular and molecular neurobiology

authors： Singh S,Thakur MK

更新日期：2011-04-01 00:00:00

abstract：:Neuropathic pain occurs as a result of peripheral or central nervous system injury. Its pathophysiology involves mainly a central sensitization mechanism that may be correlated to many molecules acting in regions involved in pain processing, such as the spinal cord. It has been demonstrated that reactive oxygen specie...

journal_title：Cellular and molecular neurobiology

authors： Guedes RP,Araújo AS,Janner D,Belló-Klein A,Ribeiro MF,Partata WA

更新日期：2008-12-01 00:00:00

abstract：:Cannabinoid (CB) ligands have demonstrated neuroprotective properties. In this study we compared the effects of a diverse set of CB ligands against β amyloid-mediated neuronal toxicity and activated microglial-conditioned media-based neurotoxicity in vitro, and compared this with a capacity to directly alter β amyloid...

journal_title：Cellular and molecular neurobiology

authors： Janefjord E,Mååg JL,Harvey BS,Smid SD

更新日期：2014-01-01 00:00:00

abstract：:The hematopoietic cell kinase (Hck) is a member of the Src family protein kinases which regulates many signal transduction pathways including cell growth, proliferation, differentiation, migration, and apoptosis. However, the expression and function of Hck after intracerebral hemorrhage (ICH) are unknown. Western blot...

journal_title：Cellular and molecular neurobiology

authors： Wang J,Chen R,Liu X,Shen J,Yan Y,Gao Y,Tao T,Shi J

更新日期：2017-03-01 00:00:00

abstract：:Cerebral hemorrhage is a series of devastating cerebrovascular diseases with high mortality, morbidity and recurrence rate. Localized and systemic immuno-reactions are involved. Aggregation of immunocytes, which were both recruited from the peripheral circulation and resident in the central nervous system, is induced ...

journal_title：Cellular and molecular neurobiology

authors： Ye L,Gao L,Cheng H

更新日期：2018-10-01 00:00:00

abstract：:1. The retinoblastoma susceptibility gene product, p105Rb (RB), is an important regulator in the control of cell proliferation, differentiation, and apoptosis. Several cellular factors that complex with RB and exert their cellular regulatory functions have been identified, such as the RB:cyclophilin A (CypA) complex. ...

journal_title：Cellular and molecular neurobiology

authors： Chiu R,Rey O,Zheng JQ,Twiss JL,Song J,Pang S,Yokoyama KK

更新日期：2003-12-01 00:00:00

abstract：:1. Accumulation of different c-erbA transcripts was studied, during rat brain maturation and in cortical neurons differentiating in a serum-free medium, by quantitative Northern blot hybridization. 2. The alpha and beta forms of c-erbA mRNAs exhibit different patterns of accumulation, with a precocious increase in the...

journal_title：Cellular and molecular neurobiology

authors： Castiglia D,Cestelli A,Di Liegro C,Bonfanti L,Di Liegro I

更新日期：1992-06-01 00:00:00

abstract：:Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society. Although significant progress has been made in depression research, the common molecular mechanism of antidepressants is still far from clearly understood. The neuroprotective eff...

journal_title：Cellular and molecular neurobiology

authors： Zheng M,Liu C,Pan F,Shi D,Ma F,Zhang Y,Zhang Y

更新日期：2011-04-01 00:00:00

abstract：:1. Nitric oxide (NO) is thought to play a neuromodulatory role in the nervous system of vertebrate and invertebrate species. In the hornworm Manduca sexta, NO-mediated signaling has been implicated in behavioral and developmental processes, but its exact function in neurons is unknown. In this study, we identify speci...

journal_title：Cellular and molecular neurobiology

authors： Zayas RM,Trimmer BA

更新日期：2007-03-01 00:00:00

abstract：:Ac2-26, a mimetic peptide of Annexin-A1, plays a vital role in the anti-inflammatory response mediated by astrocytes. In this study, we aimed to explore the underlying mechanisms of Ac2-26-mediated anti-inflammatory effect. Specifically, we investigated the inhibitory effects of Ac2-26 on lipopolysaccharide (LPS)-indu...

journal_title：Cellular and molecular neurobiology

authors： Luo Z,Wang H,Fang S,Li L,Li X,Shi J,Zhu M,Tan Z,Lu Z

更新日期：2020-05-01 00:00:00

abstract：:Reactive microglia clustering around amyloid plaques in brain is a histopathological feature of Alzheimer's disease (AD) and reflects the contribution of neuroinflammation in AD pathogenesis. β-Amyloid peptide (Aβ) has been shown to induce a range of microglial responses including chemotaxis, cytotoxicity and inflamma...

journal_title：Cellular and molecular neurobiology

authors： Zhang X,Ye P,Wang D,Liu Y,Cao L,Wang Y,Xu Y,Zhu C

更新日期：2019-07-01 00:00:00

abstract：:Glioblastoma is the most malignant primary brain tumor and is very resistant to treatment; hence, it has a poor prognosis. Neurotensin receptor type 1 (NTSR1) plays a key role in cancer malignancy and has potential therapeutic applications. However, the presence and function of neurotensin (NTS) receptors in glioblast...

journal_title：Cellular and molecular neurobiology

authors： Ayala-Sarmiento AE,Martinez-Fong D,Segovia J

更新日期：2015-08-01 00:00:00

abstract：:1. Tau, which is a microtubule-associated protein, with mRNA targeted to the axon and growth cone, is involved in axonal elongation. During postnatal development in mouse, Tau expression in cerebellar granule cells is reduced afte the second postnatal week. The aim of this work was to study the regulation of the rate ...

journal_title：Cellular and molecular neurobiology

authors： Vilá-Ortiz GJ,Santa-Coloma TA,Carminatti H,Radrizzani M

更新日期：2001-10-01 00:00:00

abstract：AIM:Poly (ADP-ribose) polymerase (PARP) is a nuclear repair enzyme whose role is widely depicted in various physiological and pathological processes. In the present study, we wanted to check the status of PARP and the role of various cell death proteases involved in apoptotic and non-apoptotic forms of cell death durin...

journal_title：Cellular and molecular neurobiology

authors： Chaitanya GV,Babu PP

更新日期：2009-06-01 00:00:00

abstract：:The study was performed to investigate the effect of combination therapy with aminoguanidine (AG) and dexamethasone (DEX) on the compression spinal cord injury (SCI) in rat. Compared to the control group, the combination therapy group with AG (75 mg/kg) and DEX (0.025 mg/kg) significantly reduced the degree of (1) spi...

journal_title：Cellular and molecular neurobiology

authors： Xu WB,Lv G,Wang YF,Lu XH,Huang T,Zhu Y,Jia LS

更新日期：2009-07-01 00:00:00

abstract：:Contextual fear conditioning is a paradigm for investigating cellular mechanisms involved in hippocampus-dependent memory. Earlier, we showed that standardised extract of Bacopa monniera (CDRI-08) improves hippocampus-dependent learning in postnatal rats by elevating the level of serotonin (5-hydroxytryptamine, 5-HT),...

journal_title：Cellular and molecular neurobiology

authors： Preethi J,Singh HK,Venkataraman JS,Rajan KE

更新日期：2014-05-01 00:00:00

abstract：:Hemorrhagic transformation (HT) is a common complication after thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) in ischemic stroke. In this article, recent research progress of HT in vivo and in vitro studies was reviewed. We have discussed new potential mechanisms and possible experimental mode...

journal_title：Cellular and molecular neurobiology

authors： Liu C,Xie J,Sun S,Li H,Li T,Jiang C,Chen X,Wang J,Le A,Wang J,Li Z,Wang J,Wang W

更新日期：2020-10-30 00:00:00

abstract：:1. The HCS2 (Helix command specific 2) gene expressed in giant command neurons for withdrawal behavior of the terrestrial snail Helix lucorum encodes a unique hybrid precursor protein that contains a Ca-binding (EF-hand motif) protein and four small peptides (CNP1-CNP4) with similar Tyr-Pro-Arg-X aminoacid sequence at...

journal_title：Cellular and molecular neurobiology

authors： Ivanova JL,Leonova OG,Popenko VI,Ierusalimsky VN,Korshunova TA,Boguslavsky DV,Malyshev AY,Balaban PM,Belyavsky AV

更新日期：2006-03-01 00:00:00

abstract：:1. Transient forebrain ischemia in adult rats, induced by 10 min of bilateral carotid occlusion and an arterial hypotension of 40 mmHg, caused substantial damage not only to CA-1 neurons in hippocampus but also to epithelial cells in lateral ventricle choroid plexus. 2. When transient forebrain ischemia was followed b...

journal_title：Cellular and molecular neurobiology

authors： Johanson CE,Palm DE,Primiano MJ,McMillan PN,Chan P,Knuckey NW,Stopa EG

更新日期：2000-04-01 00:00:00

abstract：:Neuroinflammation is an integral part of neurodegenerative diseases. Lipo-polysacharide (LPS) induces reactive astrogliosis, the cellular manifestation of neuroinflammation, in various models of neurological diseases, but its mechanism of action is still not properly known. The effect of guggulipid and nimesulide on L...

journal_title：Cellular and molecular neurobiology

authors： Niranjan R,Nath C,Shukla R

更新日期：2011-07-01 00:00:00

abstract：:The sympathoneural and the adrenomedullary systems are involved in regulation of immune processes. Their impairment has been suggested in patients with rheumatoid arthritis (RA). In this study, sympathetic response to orthostasis was evaluated in 22 RA females with <40 years of age and in 15 matched healthy controls. ...

journal_title：Cellular and molecular neurobiology

authors： Vlcek M,Rovensky J,Eisenhofer G,Radikova Z,Penesova A,Kerlik J,Imrich R

更新日期：2012-07-01 00:00:00

abstract：:1. In the retinal inner nuclear layer of the majority of species, a dopaminergic neuronal network has been visualized in either amacrine cells or the so-called interplexiform cells. 2. Binding studies of retinal dopamine receptors have revealed the existence of both D1- as well D2-subtypes. The D1-subtype was characte...

journal_title：Cellular and molecular neurobiology

authors： Schorderet M,Nowak JZ

更新日期：1990-09-01 00:00:00

abstract：:1. Coexisting with oxytocin or vasopressin in the cell bodies and nerve terminals of the hypothalamic-neurohypophysial system are smaller amounts of other peptides. For a number of these "copeptides" there is strong evidence of corelease with the major magnocellular hormones. Guided by the location of their specific r...

journal_title：Cellular and molecular neurobiology

authors： Bondy CA,Whitnall MH,Brady LS,Gainer H

更新日期：1989-12-01 00:00:00

abstract：:Chromogranin A (CHGA) plays a fundamental role in the biogenesis of catecholamine secretory granules. Changes in storage and release of CHGA in clinical and experimental hypertension prompted us to study whether genetic variation at the CHGA locus might contribute to alterations in autonomic function, and hence hypert...

journal_title：Cellular and molecular neurobiology

authors： Chen Y,Rao F,Wen G,Gayen JR,Zhang K,Vaingankar SM,Biswas N,Mahata M,Friese RS,Fung MM,Salem RM,Nievergelt C,Bhatnagar V,Hook VY,Ziegler MG,Mahata SK,Hamilton BA,O'Connor DT

更新日期：2010-11-01 00:00:00

abstract：:1. Melanin-concentrating hormone (MCH)-containing neurons within the lateral hypothalamus affect a broad spectrum of physiological and behavioral processes. The aim of this study was to examine a differentiation of rat MCH neurons dependent on their functionally related projections to the intermediolateral column (IML...

journal_title：Cellular and molecular neurobiology

authors： Harthoorn LF

更新日期：2007-02-01 00:00:00