Sodium-independent taurine binding to brain synaptic membranes.

Abstract:

:Saturable sodium-independent taurine binding to mouse and rat brain synaptic membranes was exposed after two freezing-thawing cycles combined with Triton X-100 treatments. The amount of saturable taurine binding was fairly low but was enhanced after depletion of brain taurine. Saturable taurine binding was displaceable by some convulsants and anticonvulsants but is specificity still remains to be established.

journal_name

Cell Mol Neurobiol

authors

Kontro P,Oja SS

doi

10.1007/BF00735281

subject

Has Abstract

pub_date

1983-06-01 00:00:00

pages

183-7

issue

2

eissn

0272-4340

issn

1573-6830

journal_volume

3

pub_type

杂志文章
  • Accumulation of different c-erbA transcripts during rat brain development and in cortical neurons cultured in a synthetic medium.

    abstract::1. Accumulation of different c-erbA transcripts was studied, during rat brain maturation and in cortical neurons differentiating in a serum-free medium, by quantitative Northern blot hybridization. 2. The alpha and beta forms of c-erbA mRNAs exhibit different patterns of accumulation, with a precocious increase in the...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00712930

    authors: Castiglia D,Cestelli A,Di Liegro C,Bonfanti L,Di Liegro I

    更新日期:1992-06-01 00:00:00

  • SNAP-25 contains non-acylated thiol pairs that can form intrachain disulfide bonds: possible sites for redox modulation of neurotransmission.

    abstract::Intrachain disulfide bond formation among the cysteine thiols of SNAP-25, a component of the SNARE protein complex required for neurotransmitter release, has been hypothesized to link oxidative stress and inhibition of synaptic transmission. However, neither the availability in vivo of SNAP-25 thiols, which are known ...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-011-9748-4

    authors: Foley TD,Clark AR,Stredny ES,Wierbowski BM

    更新日期:2012-03-01 00:00:00

  • Multiple mechanisms of antagonism of gamma-aminobutyric acid (GABA) responses.

    abstract::Gamma-aminobutyric acid (GABA) is one of the most important neurotransmitters in the brain. In an effort to understand the operation of the GABA receptor-ionophore complex, the antagonism of GABA responses by four substances was studied in bullfrog dorsal root ganglion cells by concentration-clamp and internal-perfusi...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00734993

    authors: Akaike N,Yakushiji T,Tokutomi N,Carpenter DO

    更新日期:1987-03-01 00:00:00

  • Correction to: Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1.

    abstract::The original version of this article unfortunately contained a typo in co-author name. ...

    journal_title:Cellular and molecular neurobiology

    pub_type: 已发布勘误

    doi:10.1007/s10571-020-00990-4

    authors: Narayan A,Hunkele A,Xu J,Bassoni DL,Pasternak GW,Pan YX

    更新日期:2020-10-31 00:00:00

  • Hydroalcoholic extract of cyperus rotundus ameliorates H2O2-induced human neuronal cell damage via its anti-oxidative and anti-apoptotic machinery.

    abstract::Hydrogen peroxide (H(2)O(2)), a major reactive oxygen species produced during oxidative stress, has been implicated in the pathophysiology of various neurodegenerative conditions. Cyperus rotundus is a traditional medicinal herb that has recently found applications in food and confectionary industries. In the current ...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-012-9865-8

    authors: Kumar KH,Khanum F

    更新日期:2013-01-01 00:00:00

  • Effect of cholinomimetics on the release and uptake of L-[3H] glutamic acid in rat neostriatum.

    abstract::The effects of cholinomimetics on the release and uptake of L-glutamic acid have been studied by means of local superfusion of rat neostriatum (in vivo) and using striatum slices (in vitro). Cholinomimetics regulate the release of L-glutamic acid through both muscarinic (m-) and nicotinic (n-) choline receptors accord...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00710999

    authors: Godukhin OV,Budantsev AYu,Selifanova OV,Agapova VN

    更新日期:1984-06-01 00:00:00

  • The role of nitric oxide in homocysteine thiolactone-induced seizures in adult rats.

    abstract::The role of NO in epileptogenesis has been studied in different experimental models, and the reported results have been highly contradictory. The current study aimed to determine the role of NO in mechanisms of D: ,L: -homocysteine-thiolactone (H) induced seizures by testing the action of L: -arginine (NO precursor) a...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-009-9444-9

    authors: Hrncić D,Rasić-Marković A,Krstić D,Macut D,Djuric D,Stanojlović O

    更新日期:2010-03-01 00:00:00

  • Endothelin-1 binding to endothelin receptors in the rat anterior pituitary gland: interaction in the recognition of endothelin-1 between ETA and ETB receptors.

    abstract::1. 125I-Endothelin (ET)-1 binding to the rat anterior pituitary gland was saturable and single, with a Kd of 71 pM and a Bmax of 120 fmol/mg. 2. When 1.0 microM BQ-123 (ETA antagonist) was added to the incubation buffer, the binding parameters were 8.3 pM and 8.0 fmol/mg, whereas 10 nM sarafotoxin S6c (ETB agonist) ex...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1023/a:1022557717481

    authors: Himeno A,Shigematsu K,Taguchi T,Niwa M

    更新日期:1998-08-01 00:00:00

  • The 21-aminosteroid U-74389F increases the number of glial fibrillary acidic protein-expressing astrocytes in the spinal cord of control and Wobbler mice.

    abstract::1. Wobbler mice suffer an autosomal recessive mutation producing severe motoneuron degeneration and dense astrogliosis, with increased levels of glial fibrillary acidic protein (GFAP) in the spinal cord and brain stem. They have been considered animal models of amyotrophic lateral sclerosis and infantile spinal muscul...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF02578387

    authors: Gonzalez Deniselle MC,Gonzalez SL,Piroli GG,Lima AE,De Nicola AF

    更新日期:1996-02-01 00:00:00

  • Molecular pharmacological dissection of short- and long-term memory.

    abstract::1. It has been discussed for over 100 years whether short-term memory (STM) is separate from, or just an early phase of, long-term memory (LTM). The only way to solve this dilemma is to find out at least one treatment that blocks STM while keeping LTM intact for the same task in the same animal. 2. The effect of a lar...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章,评审

    doi:10.1023/a:1020715800956

    authors: Izquierdo LA,Barros DM,Vianna MR,Coitinho A,deDavid e Silva T,Choi H,Moletta B,Medina JH,Izquierdo I

    更新日期:2002-06-01 00:00:00

  • Effects of adrenocortical steroids on long-term potentiation in the limbic system: basic mechanisms and behavioral consequences.

    abstract::Hippocampal structures are a major target for adrenal steroid hormones, and hence these neural regions are some of the most likely mediators of the effects of adrenocortical steroids on behavior. Memory disturbance, in particular biasing toward negative contents, are part of the symptomatology presented by depressive ...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00711580

    authors: Dubrovsky B,Gijsbers K,Filipini D,Birmingham MK

    更新日期:1993-08-01 00:00:00

  • Light-Induced Retinal Ganglion Cell Damage and the Relevant Mechanisms.

    abstract::While light is the basic element for inducing vision and modulating circadian rhythms, excessive light has been reported to have a negative effect on the survival of various types of retinal cells. Among them photoreceptors and retinal pigment epithelial (RPE) cells degeneration after light exposure is widely observed...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章,评审

    doi:10.1007/s10571-020-00819-0

    authors: Zhao Y,Shen Y

    更新日期:2020-11-01 00:00:00

  • The effect of nimodipine on calcium homeostasis and pain sensitivity in diabetic rats.

    abstract::1. The pathogenesis of diabetic neuropathy is a complex phenomenon, the mechanisms of which are not fully understood. Our previous studies have shown that the intracellular calcium signaling is impaired in primary and secondary nociceptive neurons in rats with streptozotocin (STZ)-induced diabetes. Here, we investigat...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-006-9107-z

    authors: Shutov L,Kruglikov I,Gryshchenko O,Khomula E,Viatchenko-Karpinski V,Belan P,Voitenko N

    更新日期:2006-10-01 00:00:00

  • A quantum dot probe conjugated with aβ antibody for molecular imaging of Alzheimer's disease in a mouse model.

    abstract::The treatment of Alzheimer's disease (AD) has been hampered by a lack of sensitive and specific non-invasive diagnostic methods. Quantum dots (QD) are nano-crystals with unique photo-physical properties that bypass some of the limitations of conventional dyes and imaging tools. This study is aimed to evaluate the fluo...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-013-9943-6

    authors: Feng L,Long HY,Liu RK,Sun DN,Liu C,Long LL,Li Y,Chen S,Xiao B

    更新日期:2013-08-01 00:00:00

  • Axonal contribution to subthreshold currents in Aplysia bursting pacemaker neurons.

    abstract::The contribution of axonal activity to the ionic currents which generate bursting pacemaker activity was studied by using the two-electrode voltage-clamp technique in Aplysia bursting neuron somata in conjunction with intraaxonal voltage recordings. Depolarizing voltage-clamp pulses applied to bursting cell somata tri...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00711111

    authors: Kramer RH

    更新日期:1986-09-01 00:00:00

  • Fractalkine Induces Hepcidin Expression of BV-2 Microglia and Causes Iron Accumulation in SH-SY5Y Cells.

    abstract::Fractalkine (CX3CL1) is a potent inflammatory mediator of the central nervous system, which is expressed by neurons and regulates microglial functions by binding to fractalkine receptor (CX3CR1). It has been demonstrated that neuroinflammation plays an important role in iron accumulation of the brain leading to neuron...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-019-00694-4

    authors: Pandur E,Tamási K,Pap R,Varga E,Miseta A,Sipos K

    更新日期:2019-10-01 00:00:00

  • Effect of ionophores on the processing of the beta-amyloid precursor protein in different cell lines.

    abstract::1. Alzheimer's disease is characterized by the deposition in the brain of extracellular amyloid plaques and vascular deposits consisting mostly of amyloid beta-peptide (A beta). A beta, a polypeptide of 39-43 amino acids (M(r), approximately 4 kDa), is derived proteolytically from a family of proteins of 695-770 amino...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF02088713

    authors: Lahiri DK

    更新日期:1994-08-01 00:00:00

  • Lead as an inductor of some morphological and functional changes in synaptosomes from rat brain.

    abstract::1. The effect of lead (in vivo) on the uptake of GABA, dopamine, and histidine as a precursor of histamine in synaptosomes obtained from chronically lead-treated rats was studied. 2. Lead decreased the uptake of GABA, increased the uptake of dopamine, and did not change the uptake of histidine. These effects were inde...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF02088678

    authors: Jabłońska L,Walski M,Rafałowska U

    更新日期:1994-12-01 00:00:00

  • Up-regulation of podoplanin involves in neuronal apoptosis in LPS-induced neuroinflammation.

    abstract::Podoplanin (PDPN) is a mucin-type transmembrane sialoglycoprotein expressed in multiple tissues in adult animals, including the brain, lungs, kidney, and lymphoid organs. Studies of this molecule have demonstrated its great importance in tumor metastasis, platelet aggregation, and lymphatic vessel formation. However, ...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-014-0060-y

    authors: Song Y,Shen J,Lin Y,Shen J,Wu X,Yan Y,Zhou L,Zhang H,Zhou Y,Cao M,Liu Y

    更新日期:2014-08-01 00:00:00

  • Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus.

    abstract::The myelin-associated inhibitor/Nogo-66 receptor 1 (NgR1) pathway directly functions in negative modulation of structural and electrophysiological synaptic plasticity. A previous study has established an important role of NgR1 pathway signaling in cognitive function, and we have demonstrated that multiple components o...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-013-9929-4

    authors: VanGuilder Starkey HD,Bixler GV,Sonntag WE,Freeman WM

    更新日期:2013-05-01 00:00:00

  • Choroid plexus recovery after transient forebrain ischemia: role of growth factors and other repair mechanisms.

    abstract::1. Transient forebrain ischemia in adult rats, induced by 10 min of bilateral carotid occlusion and an arterial hypotension of 40 mmHg, caused substantial damage not only to CA-1 neurons in hippocampus but also to epithelial cells in lateral ventricle choroid plexus. 2. When transient forebrain ischemia was followed b...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章,评审

    doi:10.1023/a:1007097622590

    authors: Johanson CE,Palm DE,Primiano MJ,McMillan PN,Chan P,Knuckey NW,Stopa EG

    更新日期:2000-04-01 00:00:00

  • Differential responses of rat pineal thyroxine type II 5'-deiodinase and N-acetyltransferase activities to either light exposure, isoproterenol, phenylephrine, or propranolol.

    abstract::1. Compared to pineal N-acetyl transferase (NAT) activity, which exhibited a dramatic drop following acute light exposure at night, nocturnal rat pineal thyroxine type II 5'-deiodinase (5'-D) activity was minimally influenced by the same light exposure. The injection of cycloheximide, a potent inhibitor of protein syn...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00711228

    authors: Guerrero JM,Puig-Domingo M,Santana C,Menendez-Pelaez A,Gonzalez-Brito A,Reiter RJ

    更新日期:1988-12-01 00:00:00

  • Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.

    abstract::The P2X4 receptor (P2X4R) is a member of a family of ATP-gated cation channels that are composed of three subunits. Each subunit has two transmembrane (TM) domains linked by a large extracellular loop and intracellularly located N- and C-termini. The receptors are expressed in excitable and non-excitable cells and hav...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章,评审

    doi:10.1007/s10571-010-9568-y

    authors: Stojilkovic SS,Yan Z,Obsil T,Zemkova H

    更新日期:2010-11-01 00:00:00

  • Effects of various kinds of stimulation on ornithine decarboxylase activity in superior cervical sympathetic and nodose ganglia of rats.

    abstract::Levels of cyclic nucleotides and ornithine decarboxylase (ODC) activity were examined following the application of various kinds of stimuli to superior cervical sympathetic ganglia (SCG), nodose ganglia, and vagus nerve fibers excised from the rat. The level of cyclic GMP in the SCG rose rapidly to about 4.5- to 7.5-f...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00710944

    authors: Ando M,Miwa M,Nagata Y

    更新日期:1984-03-01 00:00:00

  • Aquaporin-mediated fluid regulation in the inner ear.

    abstract::1. The sensory functions of the inner ear (hearing and balance) critically depend on the precise regulation of two fluid compartments of highly desparate ion composition, i.e., the endolymph and the perilymph. 2. The parameters volume, ion composition, and pH need to be held at homeostasis irrespective of the hydratio...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章,评审

    doi:10.1023/a:1023636620721

    authors: Beitz E,Zenner HP,Schultz JE

    更新日期:2003-06-01 00:00:00

  • Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells.

    abstract::1. Aminoalkylindoles, typified by WIN 55212-2, bind to G protein-coupled cannabinoid receptors in brain. Although cannabinoids inhibit adenylyl cyclase in NG108-15 neuroblastoma x glioma hybrid cells, cannabinoid receptor binding in these cells has not been described previously. This study compares pharmacological cha...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1023/a:1026306804802

    authors: Stark S,Pacheco MA,Childers SR

    更新日期:1997-10-01 00:00:00

  • Endogenous dopamine maintains synchronous oscillation of intracellular calcium in primary cultured-mouse midbrain neurons.

    abstract::We demonstrated synchronous oscillation of intracellular Ca2+ in cultured-mouse mid-brain neurons. This synchronous oscillation was thought to result from spontaneous and synchronous neural bursts in a synaptic neural network. We also examined the role of endogenous dopamine in neural networks showing synchronous osci...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1023/b:cemn.0000012724.79184.b6

    authors: Yasumoto F,Negishi T,Ishii Y,Kyuwa S,Kuroda Y,Yoshikawa Y

    更新日期:2004-02-01 00:00:00

  • Rab10 Disruption Results in Delayed OPC Maturation.

    abstract::Oligodendrocyte precursor cell (OPC) maturation requires membrane addition for myelin sheath formation. Since the Rab system has been shown to contribute to membrane addition in other cell types, in this study, we explored the role of Rab in OPC maturation. SiRNA and shRNA techniques and conditional knockout mice prov...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/s10571-017-0465-5

    authors: Zhang ZH,Zhao WQ,Ma FF,Zhang H,Xu XH

    更新日期:2017-10-01 00:00:00

  • S100, a brain-specific protein: localization and possible role in the snail nervous system.

    abstract::Immunofluorescence techniques were used to show that S100 is present on the surface of neuronal and glial membranes of Helix pomatia in vitro. By the method of rocket immunoelectrophoresis of aqueous , Trition, and n-pentanol extracts of snail nervous tissue, S100 was demonstrated to be mainly in the membrane fraction...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章

    doi:10.1007/BF00710684

    authors: Shtark MB,Gainutdinov KL,Khichenko VI,Starostina MV

    更新日期:1981-09-01 00:00:00

  • What can we know from pituitary-adrenal hormones about the nature and consequences of exposure to emotional stressors?

    abstract::Exposure to stress induces profound physiological and behavioral changes in the organisms and some of these changes may be important regarding stress-induced pathologies and animal models of psychiatric diseases. Consequences of stress are dependent on the duration of exposure to stressors (acute, chronic), but also o...

    journal_title:Cellular and molecular neurobiology

    pub_type: 杂志文章,评审

    doi:10.1007/s10571-012-9814-6

    authors: Armario A,Daviu N,Muñoz-Abellán C,Rabasa C,Fuentes S,Belda X,Gagliano H,Nadal R

    更新日期:2012-07-01 00:00:00