Abstract:
:Immunofluorescence techniques were used to show that S100 is present on the surface of neuronal and glial membranes of Helix pomatia in vitro. By the method of rocket immunoelectrophoresis of aqueous , Trition, and n-pentanol extracts of snail nervous tissue, S100 was demonstrated to be mainly in the membrane fraction. Anti-S100 antiserum inhibited the electrical activity of identified neurons, pointing to a relationship of this process with ionic channels of the excitable membrane. The effect of anti-S100 antiserum on the membrane was potential dependent and controlled by the Ca2+ concentration.
journal_name
Cell Mol Neurobioljournal_title
Cellular and molecular neurobiologyauthors
Shtark MB,Gainutdinov KL,Khichenko VI,Starostina MVdoi
10.1007/BF00710684subject
Has Abstractpub_date
1981-09-01 00:00:00pages
289-99issue
3eissn
0272-4340issn
1573-6830journal_volume
1pub_type
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