Lead as an inductor of some morphological and functional changes in synaptosomes from rat brain.

abstract：:The original version of this article unfortunately contained a typo in co-author name. ...

journal_title：Cellular and molecular neurobiology

authors： Narayan A,Hunkele A,Xu J,Bassoni DL,Pasternak GW,Pan YX

更新日期：2020-10-31 00:00:00

abstract：:1. The term "blood-brain barrier" describes a range of mechanisms that control the exchange of molecules between the internal environment of the brain and the rest of the body. 2. The underlying morphological feature of these barriers is the presence of tight junctions which are present between cerebral endothelial ce...

journal_title：Cellular and molecular neurobiology

authors： Saunders NR,Knott GW,Dziegielewska KM

更新日期：2000-02-01 00:00:00

abstract：:1. Taurine applied to mouse brain slices evokes a long-lasting enhancement (LLE) of corticostriatal synaptic transmission, LLE(TAU). 2. The occurrence of LLE(TAU) was significantly decreased in the presence of the specific antagonists at either D1 (SCH23390) or D2 (raclopride) dopamine (DA) receptors. 3. LLE(TAU) was ...

journal_title：Cellular and molecular neurobiology

authors： Chepkova AN,Sergeeva OA,Haas HL

更新日期：2005-06-01 00:00:00

abstract：:We have investigated the action of the recombinant neurotoxins, named Hk7a and Hk2a, whose amino acid sequences differ only in two positions, isolated from the sea anemone Anthopleura sp., on neuronal sodium currents using the whole-cell voltage-clamp techniques. The rat cerebral cortical neurons in primary culture we...

journal_title：Cellular and molecular neurobiology

authors： Xiang H,Tao W,Wang L,Wang F,Xu A

更新日期：2008-12-01 00:00:00

abstract：:microRNAs (miRNAs) comprise a class of ~18-25 nucleotide (nt) single-stranded non-coding RNAs (sncRNAs) that are the smallest known carriers of gene-encoded, post-transcriptional regulatory information in both plants and animals. There are many fundamental similarities between plant and animal miRNAs-the miRNAs of bot...

journal_title：Cellular and molecular neurobiology

authors： Zhao Y,Cong L,Lukiw WJ

更新日期：2018-01-01 00:00:00

abstract：:1. Neural angiotensinergic circuitry located in the lamina terminalis has been proposed to be involved in blood pressure regulation and fluid homeostasis. 2. ANG II binding sites have been described to be localized throughout the lamina terminalis including the subfornical organ (SFO), the median preoptic nucleus (MnP...

journal_title：Cellular and molecular neurobiology

authors： Guilhaume SS,Corrêa FM

更新日期：2001-02-01 00:00:00

abstract：:The perineurium serves as a selective, metabolically active diffusion barrier in the peripheral nervous system, which is composed of perineurial cells joined together by tight junctions (TJs). Not only are these junctions known to play an essential role in maintaining cellular polarity and tissue integrity, but also l...

journal_title：Cellular and molecular neurobiology

authors： Yin X,Liu X,Zhang Y,Zeng J,Liang X,Yang X,Hou J

更新日期：2020-10-07 00:00:00

abstract：:The prelimbic cortex (PL) is an important structure in the neural pathway integrating stress responses. Brain angiotensin is involved in cardiovascular control and modulation of stress responses. Blockade of angiotensin receptors has been reported to reduce stress responses. Acute restraint stress (ARS) is a stress mo...

journal_title：Cellular and molecular neurobiology

authors： Brasil TFS,Fassini A,Corrêa FM

更新日期：2018-01-01 00:00:00

abstract：:1. RNA interference (RNAi) is a multicomponent machinery that operates in a sequence-specific manner to repress the expression of genes in most eukaryotic cells. 2. Here we wanted to investigate in a murine neuroblastoma cell line (NBP2) (a) if replacement of the loop of the short hairpin RNA (shRNA) with a hammerhead...

journal_title：Cellular and molecular neurobiology

authors： Nahreini P,Hanson AJ,Andreatta CP,Koustas WT,Prasad KN

更新日期：2004-12-01 00:00:00

abstract：:1. The pathogenesis of diabetic neuropathy is a complex phenomenon, the mechanisms of which are not fully understood. Our previous studies have shown that the intracellular calcium signaling is impaired in primary and secondary nociceptive neurons in rats with streptozotocin (STZ)-induced diabetes. Here, we investigat...

journal_title：Cellular and molecular neurobiology

authors： Shutov L,Kruglikov I,Gryshchenko O,Khomula E,Viatchenko-Karpinski V,Belan P,Voitenko N

更新日期：2006-10-01 00:00:00

abstract：:Abeta accumulation, a hallmark of Alzheimer's disease, promotes the disease progress in multiple facets. Abeta is formed through amyloidogenic cleavage pathway of amyloid precursor protein (APP). Production of Abeta can be decreased via activation of 5-HT2C receptor, which enhances alternative APP non-amyloidogenic cl...

journal_title：Cellular and molecular neurobiology

authors： Tian XL,Yu LH,Li WQ,Hu Y,Yin M,Wang ZJ

更新日期：2015-04-01 00:00:00

abstract：:1. The electrophysiological actions of excitatory amino acids and serotonin were investigated in slices from cat neocortex in vitro. Intracellular recordings were obtained from neurons (mainly in layer V) and the drugs applied extracellularly to the same neurons by microiontophoresis. 2. Serotonin, and to some extent ...

journal_title：Cellular and molecular neurobiology

authors： Nedergaard S,Engberg I,Flatman JA

更新日期：1987-12-01 00:00:00

abstract：:Adeno-associated virus (AAV) has distinct advantages over other viral vectors in delivering genes of interest to the brain. AAV mainly transfects neurons, produces no toxicity or inflammatory responses, and yields long-term transgene expression. In this study, we first tested the hypothesis that AAV serotype 2 (AAV2) ...

journal_title：Cellular and molecular neurobiology

authors： Lin LH,Dragon DN,Jin J,Talman WT

更新日期：2011-08-01 00:00:00

abstract：:GABA is an inhibitory neurotransmitter that appears to be associated with the action of volatile anesthetics. These anesthetics potentiate GABA-induced postsynaptic currents by synaptic GABAA receptors, although recent evidence suggests that these agents also significantly affect extrasynaptic GABA receptors. However,...

journal_title：Cellular and molecular neurobiology

authors： Diniz PH,Guatimosim C,Binda NS,Costa FL,Gomez MV,Gomez RS

更新日期：2014-01-01 00:00:00

abstract：:The intention of this review is to emphasize the current knowledge about the extent and importance of the substances co-localized with magnocellular arginine vasopressin (AVP) and oxytocin (OXY) as potential candidates for the gradual clarification of their actual role in the regulation of hydromineral homeostasis. Ma...

journal_title：Cellular and molecular neurobiology

authors： Bundzikova J,Pirnik Z,Zelena D,Mikkelsen JD,Kiss A

更新日期：2008-12-01 00:00:00

abstract：:Ubiquitination of proteins and their degradation within the proteasome has emerged as the major proteolytic mechanism used by mammalian cells to regulate cytosolic and nuclear protein levels. Substrate ubiquitylation is mediated by ubiquitin (Ub) ligases, also called E3 Ub ligases. HECT-E3 Ub ligases are characterized...

journal_title：Cellular and molecular neurobiology

authors： Zhang L,Kang L,Bond W,Zhang N

更新日期：2009-02-01 00:00:00

abstract：:As a novel cell cycle inhibitor, PHB2 controls the G1/S transition in cycling cells in a complex manner. Its aberrant expression is closely related to cell carcinogenesis. While its expression and role in peripheral nervous system lesion and repair were still unknown. Here, we performed an acute sciatic nerve crush (S...

journal_title：Cellular and molecular neurobiology

authors： Long L,Huang Y,Wu H,Luan W,Zhang Q,Wen H,Ding T,Wang Y

更新日期：2013-07-01 00:00:00

abstract：:1. Interleukin-10 (IL-10) has a wide range of activities in the immune system such as modulation of interferon-gamma (IFN-gamma) and antibody production. The neuropeptide hormone corticotropin (ACTH) has similar activities, suggesting that a bidirectional communication mechanism operates between the immune and the neu...

journal_title：Cellular and molecular neurobiology

authors： Hughes TK,Cadet P,Rady PL,Tyring SK,Chin R,Smith EM

更新日期：1994-02-01 00:00:00

abstract：:Established cancer cell lines are routinely used to study cancer. Several factors such as serial passage may affect the reproducibility of experiments with cancer cell lines, but few researches focused on these changes. In the present study, different morphology and decreased tumorigenicity were observed in late passa...

journal_title：Cellular and molecular neurobiology

authors： Zeng Y,Wang X,Wang J,Yi R,Long H,Zhou M,Luo Q,Zhai Z,Song Y,Qi S

更新日期：2018-08-01 00:00:00

abstract：:1. Alzheimer's disease is characterized by the deposition in the brain of extracellular amyloid plaques and vascular deposits consisting mostly of amyloid beta-peptide (A beta). A beta, a polypeptide of 39-43 amino acids (M(r), approximately 4 kDa), is derived proteolytically from a family of proteins of 695-770 amino...

journal_title：Cellular and molecular neurobiology

authors： Lahiri DK

更新日期：1994-08-01 00:00:00

abstract：:1. It has been discussed for over 100 years whether short-term memory (STM) is separate from, or just an early phase of, long-term memory (LTM). The only way to solve this dilemma is to find out at least one treatment that blocks STM while keeping LTM intact for the same task in the same animal. 2. The effect of a lar...

journal_title：Cellular and molecular neurobiology

authors： Izquierdo LA,Barros DM,Vianna MR,Coitinho A,deDavid e Silva T,Choi H,Moletta B,Medina JH,Izquierdo I

更新日期：2002-06-01 00:00:00

abstract：:Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society. Although significant progress has been made in depression research, the common molecular mechanism of antidepressants is still far from clearly understood. The neuroprotective eff...

journal_title：Cellular and molecular neurobiology

authors： Zheng M,Liu C,Pan F,Shi D,Ma F,Zhang Y,Zhang Y

更新日期：2011-04-01 00:00:00

abstract：AIM:Poly (ADP-ribose) polymerase (PARP) is a nuclear repair enzyme whose role is widely depicted in various physiological and pathological processes. In the present study, we wanted to check the status of PARP and the role of various cell death proteases involved in apoptotic and non-apoptotic forms of cell death durin...

journal_title：Cellular and molecular neurobiology

authors： Chaitanya GV,Babu PP

更新日期：2009-06-01 00:00:00

abstract：:In our previous research, the formation and development of age-related cataract (ARC) is associated with DNA hypermethylation of some genes in lens epithelial cells (LECs). This study aimed to investigate the expression profile of DNA methylation- and transcriptional repression-associated genes in LECs of ARC. The exp...

journal_title：Cellular and molecular neurobiology

authors： Wang Y,Zhang G,Kang L,Guan H

更新日期：2017-04-01 00:00:00

abstract：:1. Two giant peptidergic neurons, VD1 and RPD2, of the visceral ganglion and right parietal ganglion of Lymnaea stagnalis, respectively, play an important role in the modulation of complex physiological and behavioral adjustments that occur as a result of changes in O2 availability. 2. By cDNA cloning, we have identif...

journal_title：Cellular and molecular neurobiology

authors： Bogerd J,Van Kesteren RE,Van Heerikhuizen H,Geraerts WP,Veenstra J,Smit AB,Joosse J

更新日期：1993-04-01 00:00:00

abstract：:The myelin-associated inhibitor/Nogo-66 receptor 1 (NgR1) pathway directly functions in negative modulation of structural and electrophysiological synaptic plasticity. A previous study has established an important role of NgR1 pathway signaling in cognitive function, and we have demonstrated that multiple components o...

journal_title：Cellular and molecular neurobiology

authors： VanGuilder Starkey HD,Bixler GV,Sonntag WE,Freeman WM

更新日期：2013-05-01 00:00:00

abstract：:1. Wobbler mice suffer an autosomal recessive mutation producing severe motoneuron degeneration and dense astrogliosis, with increased levels of glial fibrillary acidic protein (GFAP) in the spinal cord and brain stem. They have been considered animal models of amyotrophic lateral sclerosis and infantile spinal muscul...

journal_title：Cellular and molecular neurobiology

authors： Gonzalez Deniselle MC,Gonzalez SL,Piroli GG,Lima AE,De Nicola AF

更新日期：1996-02-01 00:00:00

abstract：:EP3 is prostaglandin E2 receptor subtype 3 and mediates the activation of several signaling pathways, changing in cAMP levels, calcium mobilization, and activation of phospholipase C. Previous studies demonstrated a direct role for EP3 in various neurodegenerative disorders, such as stroke and Alzheimer disease. Howev...

journal_title：Cellular and molecular neurobiology

authors： Ni H,Shen J,Song Y,Cao M,Liu X,Huang J,Zhang W,Xie L,Ning X,Ke K

更新日期：2016-08-01 00:00:00

abstract：:Traumatic brain injury (TBI) causes permanent neurological and cognitive impairments. Effective pharmacological interventions remain elusive. Spermidine is a polyamine compound found in our body that may play a role in brain development and congenital function. In this study, we aimed to investigate the therapeutic po...

journal_title：Cellular and molecular neurobiology

authors： Huang J,Zhang H,Zhang J,Yu H,Lin Z,Cai Y

更新日期：2020-08-01 00:00:00

abstract：:Organotellurium compounds have been synthesized since 1840, but pharmacological and toxicological studies about them are still incipient. Therefore, the objective of this study was to verify the effect of acute administration of the organochalcogen 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one on some parameters of o...

journal_title：Cellular and molecular neurobiology

authors： Funchal C,Carvalho CA,Gemelli T,Centeno AS,Guerra RB,Salvador M,Dani C,Coitinho A,Gomez R

更新日期：2010-10-01 00:00:00