Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.

abstract：:The anorexigenic molecule nesfatin-1 has recently been taken as a potential mood regulator, but the potential mechanisms remain unknown. Results of our previous study have demonstrated that nesfatin-1 could induce anxiety- and depression-like behaviors in rats, accompanied by the hyperactivity of the hypothalamic-pitu...

journal_title：Cellular and molecular neurobiology

authors： Chen Z,Xu YY,Ge JF,Chen FH

更新日期：2018-04-01 00:00:00

abstract：:1. Studies conducted on the rat arcuate nucleus, an area involved in the development and control of LH and FSH secretion, have shown the existence of hormonally regulated developmental sex differences in synaptic patterns and estrogen-induced synaptic plasticity during adult life. Several questions raised by these fin...

journal_title：Cellular and molecular neurobiology

authors： Naftolin F,Leranth C,Horvath TL,Garcia-Segura LM

更新日期：1996-04-01 00:00:00

abstract：:Our previous study showed that RalA-binding protein 1 (RLIP76) is overexpressed in gliomas and is associated with higher tumour grade and decreased patient survival. Furthermore, RLIP76 downregulation increases chemosensitivity of glioma cells to temozolomide by inducing apoptosis. However, other mechanisms underlying...

journal_title：Cellular and molecular neurobiology

authors： Zhang C,Cai Z,Liang Q,Wang Q,Lu Y,Hu L,Hu G

更新日期：2017-04-01 00:00:00

abstract：:1. We measured changes in resting membrane potential (Em) and Na-K pump activity, assayed by ouabain-sensitive 86Rb uptake, in response to carbamylcholine (CCh) and its continued presence in single rat skeletal myotubes in culture. 2. CCh caused immediate depolarization from control Em (-80 to -85 mV) to near 0 follow...

journal_title：Cellular and molecular neurobiology

authors： Brodie C,Sampson SR

更新日期：1988-12-01 00:00:00

abstract：:1. Angiotensin II receptors have been studied by quantitative autoradiography in selected brain areas of young (2-week-old) and adult (8-week-old) rats. 2. In young rats, angiotensin II receptors were present in brain areas which did not express receptors in the adult brain, such as thalamic nuclei, cortical areas, an...

journal_title：Cellular and molecular neurobiology

authors： Tsutsumi K,Saavedra JM

更新日期：1991-04-01 00:00:00

abstract：:Cerebral hemorrhage is a series of devastating cerebrovascular diseases with high mortality, morbidity and recurrence rate. Localized and systemic immuno-reactions are involved. Aggregation of immunocytes, which were both recruited from the peripheral circulation and resident in the central nervous system, is induced ...

journal_title：Cellular and molecular neurobiology

authors： Ye L,Gao L,Cheng H

更新日期：2018-10-01 00:00:00

abstract：:Phenylketonuria (PKU) is an inherited metabolic disorder caused by deficiency of phenylalanine hydroxylase which leads to accumulation of phenylalanine and its metabolites in tissues of patients with severe neurological involvement. Recently, many studies in animal models or patients have reported the role of oxidativ...

journal_title：Cellular and molecular neurobiology

authors： Moraes TB,Jacques CE,Rosa AP,Dalazen GR,Terra M,Coelho JG,Dutra-Filho CS

更新日期：2013-03-01 00:00:00

abstract：:Besides clinical and imaging techniques, there is a lack of molecular makers for the diagnosis of Parkinson's disease (PD). There is an immense need to develop biomarkers associated with the phenotypes which may be valuable for individualized treatment. Single-nucleotide polymorphisms (PARK2: Ser167Asn (G>A) and Val38...

journal_title：Cellular and molecular neurobiology

authors： Sanyal J,Anirudhan A,Banerjee TK,Guha G,Ramakrishnan Veerabathiran,Murugesan R,Ahmed SSJS,Rao VR

更新日期：2020-04-01 00:00:00

abstract：:The aim of this review was to give a general aspect of the sensorial function of the striatum related to pain modulation, which was intensively studied in our laboratory. We analyse the effect of electrical and chemical stimulation of the striatum on the orofacial pain, especially that produced by tooth pulp stimulati...

journal_title：Cellular and molecular neurobiology

authors： Barceló AC,Filippini B,Pazo JH

更新日期：2012-01-01 00:00:00

abstract：:1. The proteins of large dense-core vesicles (LDV) in neuroendocrine tissues are well characterized. Secretory components comprise chromogranins and neuropeptides. Intrinsic membrane proteins include cytochrome b-561, transporters, SV2, synaptotagmin, and synaptobrevin. 2. The effects of stimulation and of second mess...

journal_title：Cellular and molecular neurobiology

authors： Winkler H,Fischer-Colbrie R

更新日期：1998-04-01 00:00:00

abstract：:Bone morphogenic protein (BMP) signaling is crucial for coordinated synaptic growth and plasticity. Here, we show that the nuclear LEM-domain protein MAN1 is a negative regulator of synaptic growth at Drosophila larval and adult neuromuscular junctions (NMJs). Loss of MAN1 is associated with synaptic structural defect...

journal_title：Cellular and molecular neurobiology

authors： Laugks U,Hieke M,Wagner N

更新日期：2017-08-01 00:00:00

abstract：:The ataxia-telangiectasia mutated (ATM) protein is regarded as the linchpin of cellular defenses to stress. Deletion of ATM results in strong oxidative stress and degenerative diseases in the nervous system. However, the role of ATM in neuronal ischemic preconditioning and lethal ischemic injury is still largely unkno...

journal_title：Cellular and molecular neurobiology

authors： Xie GH,Dai HJ,Liu F,Zhang YP,Zhu L,Nie JJ,Wu JH

更新日期：2020-07-01 00:00:00

abstract：:We have previously demonstrated that alpha2-adrenoceptors regulate hypothalamic magnocellular oxytocinergic (OXY) neurons in Sprague Dawley rats. Here we investigated whether activation/inhibition of alpha2-adrenoceptors may similarly trigger/downregulate the activity of OXY neurons in control Long Evans (+/+) and per...

journal_title：Cellular and molecular neurobiology

authors： Bundzikova J,Pirnik Z,Zelena D,Mikkelsen JD,Kiss A

更新日期：2009-09-01 00:00:00

abstract：:Matrix metalloproteinase-1 (MMP-1), a member of the matrix metalloproteinases family, plays an integral role in extracellular matrix degradation and has been reportedly involved in the regulation of the brain or spinal cord traumatic neurovascular remodeling. Although the critical involvement of MMP-1 in the metastasi...

journal_title：Cellular and molecular neurobiology

authors： Zhou Y,Cui Z,Xia X,Liu C,Zhu X,Cao J,Wu Y,Zhou L,Ben Z,Song Y,Zhang H,Zhang D

更新日期：2014-11-01 00:00:00

abstract：:1. A novel tridecapeptide was isolated from extracts of bovine adrenal medulla chromaffin vesicles and the primary structure determined to be SVPHFSDEDKDPE. 2. This peptide is identical to the C termini of human and porcine 7B2 and is highly homologous to the same region of the mouse and Xenopus lavis protein. 3. In a...

journal_title：Cellular and molecular neurobiology

authors： Sigafoos J,Chestnut WG,Merrill BM,Taylor LC,Diliberto EJ Jr,Viveros OH

更新日期：1993-06-01 00:00:00

abstract：:Reeler heterozygous mice (reln+/-) are seemingly normal but haplodeficient in reln, a gene implicated in autism. Structural/neurochemical alterations in the reln+/- brain are subtle and difficult to demonstrate. Therefore, the usefulness of these mice in translational research is still debated. As evidence implicated ...

journal_title：Cellular and molecular neurobiology

authors： Castagna C,Merighi A,Lossi L

更新日期：2019-08-01 00:00:00

abstract：:Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by the selective loss of nigrostriatal dopaminergic neurons. However, the molecular pathways leading to the dopaminergic neuron degeneration have remained obscure until recently. Reports demonstrated that reduction of b...

journal_title：Cellular and molecular neurobiology

authors： Yuan Y,Sun J,Zhao M,Hu J,Wang X,Du G,Chen NH

更新日期：2010-08-01 00:00:00

abstract：:1. Platelet-derived growth factor (PDGF) plays an important role not only in mesenchyme-derived tissues, but also in the mammalian central nervous system. The Patch mutant (Ph/+) lacks one copy of the PDGFR-alpha gene. However, it is not clear whether there are differences in expression of PDGF receptor alpha-subunit ...

journal_title：Cellular and molecular neurobiology

authors： Zhang FX,Hutchins JB

更新日期：1996-08-01 00:00:00

abstract：:The intention of this review is to emphasize the current knowledge about the extent and importance of the substances co-localized with magnocellular arginine vasopressin (AVP) and oxytocin (OXY) as potential candidates for the gradual clarification of their actual role in the regulation of hydromineral homeostasis. Ma...

journal_title：Cellular and molecular neurobiology

authors： Bundzikova J,Pirnik Z,Zelena D,Mikkelsen JD,Kiss A

更新日期：2008-12-01 00:00:00

abstract：:1. Neurotrophins and serotonin have both been implicated in the pathophysiology of depression and in the mechanisms of antidepressant treatments. 2. Brain-derived neurotrophic factor (BDNF) influences the growth and plasticity of serotonergic (5-HT) neurons via the activation of trkB receptor. 3. Transgenic mice overe...

journal_title：Cellular and molecular neurobiology

authors： Koponen E,Rantamäki T,Voikar V,Saarelainen T,MacDonald E,Castrén E

更新日期：2005-09-01 00:00:00

abstract：:Pulsed radiofrequency (PRF) treatment involves the pulsed application of a radiofrequency electric field to a nerve. The technology offers pain relief for patients suffering from chronic pain who do not respond well to conventional treatments. We tested whether PRF treatment attenuated complete Freund's adjuvant (CFA)...

journal_title：Cellular and molecular neurobiology

authors： Chen KH,Yang CH,Juang SE,Huang HW,Cheng JK,Sheen-Chen SM,Cheng JT,Lin CR

更新日期：2014-03-01 00:00:00

abstract：:1. Growth cones of cultured dorsal root ganglion neurons from mice were irradiated using a mercury lamp. 2. The flux of particles of fast retrograde axoplasmic transport decreased promptly after light irradiation without a change in velocity. 3. That of anterograde transport decreased as well, but with a significant l...

journal_title：Cellular and molecular neurobiology

authors： Kano M,Tashiro H,Kawakami T,Takenaka T,Gotoh H

更新日期：1995-06-01 00:00:00

abstract：:The perineurium serves as a selective, metabolically active diffusion barrier in the peripheral nervous system, which is composed of perineurial cells joined together by tight junctions (TJs). Not only are these junctions known to play an essential role in maintaining cellular polarity and tissue integrity, but also l...

journal_title：Cellular and molecular neurobiology

authors： Yin X,Liu X,Zhang Y,Zeng J,Liang X,Yang X,Hou J

更新日期：2020-10-07 00:00:00

abstract：:This study tested whether the glial cells are involved in the exciting effects of doxapram on brainstem slice in vitro. Experiments were performed in brainstem slice preparations from neonatal rats. The medial area of nucleus retrofacialis (mNRF) and the hypoglossal nerve (XII nerve) were contained in the preparations...

journal_title：Cellular and molecular neurobiology

authors： Li GC,Zhang HT,Jiao YG,Wu ZH,Fang F,Cheng J

更新日期：2010-07-01 00:00:00

abstract：:The hypothesis that peripheral, skeletal muscle tissue contains a trophic factor supporting central neurons has recently been investigated in vitro by supplementing the culture medium of spinal cord neurons with muscle extracts and fractions of extract. We extended these studies asking whether or not a trophic factor ...

journal_title：Cellular and molecular neurobiology

authors： Popiela H,Porter T,Beach RL,Festoff BW

更新日期：1984-03-01 00:00:00

abstract：:The myelin-associated inhibitor/Nogo-66 receptor 1 (NgR1) pathway directly functions in negative modulation of structural and electrophysiological synaptic plasticity. A previous study has established an important role of NgR1 pathway signaling in cognitive function, and we have demonstrated that multiple components o...

journal_title：Cellular and molecular neurobiology

authors： VanGuilder Starkey HD,Bixler GV,Sonntag WE,Freeman WM

更新日期：2013-05-01 00:00:00

abstract：:1. The role of oxidative stress, and accordingly uncontrolled reactive oxygen species generation/action, have been widely documented in a number of different neuronal pathologies. However, the concept of pharmacological interventions in prevention and therapy of oxidative stress-related diseases has not found adequate...

journal_title：Cellular and molecular neurobiology

authors： Stolc S,Snirc V,Májeková M,Gáspárová Z,Gajdosíková A,Stvrtina S

更新日期：2006-10-01 00:00:00

abstract：:Both sex and steroid hormones are important to consider in human ischemic stroke and its experimental models. Stroke initiates a cascade of changes that lead to neural cell death, but also activates endogenous protective processes that counter the deleterious consequences of ischemia. Steroids may be part of these cer...

journal_title：Cellular and molecular neurobiology

authors： Guennoun R,Zhu X,Fréchou M,Gaignard P,Slama A,Liere P,Schumacher M

更新日期：2019-05-01 00:00:00

abstract：:1. An identified dopaminergic interneuron (RPeD1) of the snail Lymnaea stagnalis, makes specific synaptic connections with a number of target (VI and VJ) but not non-target (VF and RPB) neurons in vivo. When cultured in vitro with both target and non-target cells, RPeD1 re-establishes synapses with target cells only. ...

journal_title：Cellular and molecular neurobiology

authors： Spencer GE,Lukowiak K,Syed NI

更新日期：1996-10-01 00:00:00

abstract：:Naked2 (NKD2), one member of Naked family, has been shown to negatively regulate Wnt/β-catenin signaling pathway. It has been recognized that NKD2 plays a vital role in cell homeostasis and prevention of tumorigenesis. However, NKD2 expression and its functional role in the brain in neuroinflammatory processes remain ...

journal_title：Cellular and molecular neurobiology

authors： Cui Z,Zhou L,Song Y,Liu C,Zhu G,Wu X,Yan Y,Xia X,Duan C,Zhou Y,Huang Y,Zhang D

更新日期：2016-01-01 00:00:00