Abstract:
:1. A novel tridecapeptide was isolated from extracts of bovine adrenal medulla chromaffin vesicles and the primary structure determined to be SVPHFSDEDKDPE. 2. This peptide is identical to the C termini of human and porcine 7B2 and is highly homologous to the same region of the mouse and Xenopus lavis protein. 3. In all these species the homologous peptide is preceded by a pair of lysine residues, a potential proteolytic processing site. 4. Ser6 is part of a well-conserved casein kinase II consensus phosphorylation sequence. Evidence for phosphorylation of this residue was obtained during Edman sequencing. 5. Thus, this novel adrenal medullary probably arises from the posttranslational processing of the bovine 7B2 protein.
journal_name
Cell Mol Neurobioljournal_title
Cellular and molecular neurobiologyauthors
Sigafoos J,Chestnut WG,Merrill BM,Taylor LC,Diliberto EJ Jr,Viveros OHdoi
10.1007/BF00733755subject
Has Abstractpub_date
1993-06-01 00:00:00pages
271-8issue
3eissn
0272-4340issn
1573-6830journal_volume
13pub_type
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