Projection-dependent differentiation of melanin-concentrating hormone-containing neurons.

abstract：:Exposure to stress induces profound physiological and behavioral changes in the organisms and some of these changes may be important regarding stress-induced pathologies and animal models of psychiatric diseases. Consequences of stress are dependent on the duration of exposure to stressors (acute, chronic), but also o...

journal_title：Cellular and molecular neurobiology

authors： Armario A,Daviu N,Muñoz-Abellán C,Rabasa C,Fuentes S,Belda X,Gagliano H,Nadal R

更新日期：2012-07-01 00:00:00

abstract：:We have used the nervous system of the medicinal leech as a preparation to study the molecular basis of neural repair. The leech central nervous system, unlike mammalian CNS, can regenerate to restore function, and contains identified nerve cells of known function and connectivity. We have constructed subtractive cDNA...

journal_title：Cellular and molecular neurobiology

authors： Wang WZ,Emes RD,Christoffers K,Verrall J,Blackshaw SE

更新日期：2005-03-01 00:00:00

abstract：:(1) There is increasing evidence that the cerebral endothelium and the blood-brain barrier (BBB) plays an important role in the oxidative stress-induced brain damage. The aim of the present study was to investigate the role of interendothelial junctional proteins in the BBB permeability increase induced by oxidative s...

journal_title：Cellular and molecular neurobiology

authors： Krizbai IA,Bauer H,Bresgen N,Eckl PM,Farkas A,Szatmári E,Traweger A,Wejksza K,Bauer HC

更新日期：2005-02-01 00:00:00

abstract：:1. Nitric oxide (NO) is thought to play a neuromodulatory role in the nervous system of vertebrate and invertebrate species. In the hornworm Manduca sexta, NO-mediated signaling has been implicated in behavioral and developmental processes, but its exact function in neurons is unknown. In this study, we identify speci...

journal_title：Cellular and molecular neurobiology

authors： Zayas RM,Trimmer BA

更新日期：2007-03-01 00:00:00

abstract：:1. Synaptic vesicles (SVs) mediate fast regulated secretion of classical neurotransmitters. In order to perform their task SVs rely on a restrict set of membrane proteins. The mechanisms responsible for targeting these proteins to the SV membrane are still poorly understood. 2. Likewise, little is known about the intr...

journal_title：Cellular and molecular neurobiology

authors： Prado VF,Prado MA

更新日期：2002-12-01 00:00:00

abstract：:Inhibitory mechanism of cerebellum epileptic activity can be involved depending on the intensity and frequency of seizure convulsions. N-methyl-D-aspartate receptors (NMDARs) play key roles in excitatory synaptic transmission and have been implicated in neurological disorders: in cerebellum, they have specific charact...

journal_title：Cellular and molecular neurobiology

authors： Girardi E,Auzmendi J,Charó N,Gori MB,Castro M

更新日期：2010-10-01 00:00:00

abstract：:1. Hypothalamic magnocellular neurons synthesize, store, and secrete large quantities of the neuropeptides, vasopressin (VP) and oxytocin (OT), which are synthesized as protein precursors also containing proteins called neurophysins. These protein precursors are sorted through the regulated secretory pathway (RSP), pa...

journal_title：Cellular and molecular neurobiology

authors： Zhang BJ,Yamashita M,Fields R,Kusano K,Gainer H

更新日期：2005-06-01 00:00:00

abstract：:1. The sensory functions of the inner ear (hearing and balance) critically depend on the precise regulation of two fluid compartments of highly desparate ion composition, i.e., the endolymph and the perilymph. 2. The parameters volume, ion composition, and pH need to be held at homeostasis irrespective of the hydratio...

journal_title：Cellular and molecular neurobiology

authors： Beitz E,Zenner HP,Schultz JE

更新日期：2003-06-01 00:00:00

abstract：:The purpose of the study was to examine the nanoscale distribution and density of the VEGFR-2 membrane receptor on the endothelial cell surface of glioma microvasculature. Immunofluorescence and atomic force microscopy combined with immunogold labeling techniques were used to characterize and determine the position of...

journal_title：Cellular and molecular neurobiology

authors： Zhou D,Zhan S,Zhou D,Li Z,Lin X,Tang K,Shu H,Chen G,Zeng S,Cai Y,Jiang X

更新日期：2011-07-01 00:00:00

abstract：:The irrefutable change in the expression of brain-enriched microRNAs (miRNAs) following ischemic stroke has promoted the development of radical miRNA-based therapeutics encompassing neuroprotection and neuronal restoration. Our previous report on the systems-level prediction of miR-9 in post-stroke-induced neurogenesi...

journal_title：Cellular and molecular neurobiology

authors： Nampoothiri SS,Rajanikant GK

更新日期：2019-03-01 00:00:00

abstract：:The pathogenesis of Alzheimer's disease (AD) has been strongly associated with the accumulation of amyloid beta (Aβ) peptides in brain, and immunotherapy targeting Aβ provides potential for AD prevention. A clinical trial in which AD patients were immunized with Aβ42 peptide was stopped when 6% of participants showed ...

journal_title：Cellular and molecular neurobiology

authors： Lambracht-Washington D,Qu BX,Fu M,Anderson LD Jr,Stüve O,Eagar TN,Rosenberg RN

更新日期：2011-08-01 00:00:00

abstract：:Endothelins regulate cellular functions in the mammalian brain through the endothelin receptors A and B (EDNRA and EDNRB). In this study, we investigated the role of EDNRB on cell proliferation in the cerebellum by using the spotting lethal (sl) rat, which carries a naturally occurring deletion in the EDNRB gene. Prol...

journal_title：Cellular and molecular neurobiology

authors： Vidovic M,Chen MM,Lu QY,Kalloniatis KF,Martin BM,Tan AH,Lynch C,Croaker GD,Cass DT,Song ZM

更新日期：2008-12-01 00:00:00

abstract：:1. Alpha-synuclein is known to play an important role in the pathogenesis of Parkinson's disease (PD). The pathogenicity of alpha-synuclein is related to its ability to form intraneuronal inclusions. The inclusions, which are found in brains of patients with PD and diffuse Lewy body disease consist partially of C-term...

journal_title：Cellular and molecular neurobiology

authors： Zach S,Bueler H,Hengerer B,Gillardon F

更新日期：2007-06-01 00:00:00

abstract：:Since gonadal female hormones act on and protect neurons, it is well known that the female brain is less vulnerable to stroke or other brain insults than the male brain. Although glial functions have been shown to affect the vulnerability of the brain, little is known if such a sex difference exists in glia, much less...

journal_title：Cellular and molecular neurobiology

authors： Morizawa Y,Sato K,Takaki J,Kawasaki A,Shibata K,Suzuki T,Ohta S,Koizumi S

更新日期：2012-08-01 00:00:00

abstract：:Neuroinflammation is an integral part of neurodegenerative diseases. Lipo-polysacharide (LPS) induces reactive astrogliosis, the cellular manifestation of neuroinflammation, in various models of neurological diseases, but its mechanism of action is still not properly known. The effect of guggulipid and nimesulide on L...

journal_title：Cellular and molecular neurobiology

authors： Niranjan R,Nath C,Shukla R

更新日期：2011-07-01 00:00:00

abstract：:1. The aim of these studies was to test the hypothesis that glutamate is the principal excitatory neurotransmitter in the sympathetic premotor pathway from the rostral ventrolateral medulla (RVLM) to the sympathetic preganglionic neurons (SPNs) in the thoracic spinal cord. 2. Iontophoretic and pressure ejection of glu...

journal_title：Cellular and molecular neurobiology

authors： Morrison SF

更新日期：2003-10-01 00:00:00

abstract：:1. In the retinal inner nuclear layer of the majority of species, a dopaminergic neuronal network has been visualized in either amacrine cells or the so-called interplexiform cells. 2. Binding studies of retinal dopamine receptors have revealed the existence of both D1- as well D2-subtypes. The D1-subtype was characte...

journal_title：Cellular and molecular neurobiology

authors： Schorderet M,Nowak JZ

更新日期：1990-09-01 00:00:00

abstract：:1. The effect of lead (in vivo) on the uptake of GABA, dopamine, and histidine as a precursor of histamine in synaptosomes obtained from chronically lead-treated rats was studied. 2. Lead decreased the uptake of GABA, increased the uptake of dopamine, and did not change the uptake of histidine. These effects were inde...

journal_title：Cellular and molecular neurobiology

authors： Jabłońska L,Walski M,Rafałowska U

更新日期：1994-12-01 00:00:00

abstract：:Spinal cord injury (SCI) remains a formidable challenge in the clinic. In the current study, we examined the effects of the TLX gene on the proliferation and neuronal differentiation of dermal multipotent stem cells (DMSCs) in vitro and the potential of these cells to improve SCI in rats in vivo. DMSCs were stably tra...

journal_title：Cellular and molecular neurobiology

authors： Wang T,Ren X,Xiong J,Zhang L,Qu J,Xu W

更新日期：2011-04-01 00:00:00

abstract：:Ischemic preconditioning (IPC) represents an important adaptation of CNS to sub-lethal ischemia, which results in increased tolerance of CNS to the lethal ischemia. Ischemia-induced mitochondrial apoptosis is considered to be an important event leading to neuronal cell death after cerebral blood flow arrest. In presen...

journal_title：Cellular and molecular neurobiology

authors： Racay P,Chomova M,Tatarkova Z,Kaplan P,Hatok J,Dobrota D

更新日期：2009-09-01 00:00:00

abstract：:1. Taurine applied to mouse brain slices evokes a long-lasting enhancement (LLE) of corticostriatal synaptic transmission, LLE(TAU). 2. The occurrence of LLE(TAU) was significantly decreased in the presence of the specific antagonists at either D1 (SCH23390) or D2 (raclopride) dopamine (DA) receptors. 3. LLE(TAU) was ...

journal_title：Cellular and molecular neurobiology

authors： Chepkova AN,Sergeeva OA,Haas HL

更新日期：2005-06-01 00:00:00

abstract：:The Pax5, a B-cell-Specific Activator Protein (BSAP) and redox-sensitive transcription factor, is expressed in the immune-privileged brain, B-lymphocytes, lymph nodes and spleen. PAX5-mediated immune pathway has also been described in the progression of Glioblastoma multiforme. However, the status of Pax5 and its role...

journal_title：Cellular and molecular neurobiology

authors： Maurya SK,Mishra R

更新日期：2018-05-01 00:00:00

abstract：:1. We studied the effect of isolation stress in 3- and 12-month-old rats individually housed in metabolic cages for 7 days. Urine (24 hr) was collected daily from one group of animals of each age. The other group was tested in an open field and on a hot plate on days 1 and 7. 2. Total deambulation in the open-field te...

journal_title：Cellular and molecular neurobiology

authors： Gil MC,Aguirre JA,Lemoine AP,Segura ET,Barontini M,Armando I

更新日期：1999-10-01 00:00:00

abstract：:Astragalosides (AST) are reported to be neuroprotective in focal cerebral ischemic models in vivo. In this study, the direct effect of AST against oxygen and glucose deprivation (OGD) including neuronal injury and the underlying mechanisms in vitro were investigated. 5 h OGD followed by 24 h of reperfusion [adding bac...

journal_title：Cellular and molecular neurobiology

authors： Chiu BY,Chang CP,Lin JW,Yu JS,Liu WP,Hsu YC,Lin MT

更新日期：2014-08-01 00:00:00

abstract：:P2X3 receptor expression in various tissues appears to be modulated by age. In the present study, we used single cell RT-PCR to determine the number of P2X3 positive myenteric neurons at different stages of guinea pig postnatal development, and we tested if similar changes also occur to other myenteric P2X receptors. ...

journal_title：Cellular and molecular neurobiology

authors： Loera-Valencia R,Jiménez-Vargas NN,Villalobos EC,Juárez EH,Lomas-Ramos TL,Espinosa-Luna R,Montaño LM,Huizinga JD,Barajas-López C

更新日期：2014-07-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is one of the most important neurotransmitters in the brain. In an effort to understand the operation of the GABA receptor-ionophore complex, the antagonism of GABA responses by four substances was studied in bullfrog dorsal root ganglion cells by concentration-clamp and internal-perfusi...

journal_title：Cellular and molecular neurobiology

authors： Akaike N,Yakushiji T,Tokutomi N,Carpenter DO

更新日期：1987-03-01 00:00:00

abstract：:1. We investigated the association of c-Jun with apoptosis within retinal tissue. Explants of the retina of neonatal rats were subject to a variety of procedures that cause apoptosis of specific classes of retinal cells at distinct stages of differentiation. The expression of c-Jun was detected by Western Blot, and im...

journal_title：Cellular and molecular neurobiology

authors： Chiarini LB,de Freitas FG,Leal-Ferreira ML,Tolkovsky A,Linden R

更新日期：2002-12-01 00:00:00

abstract：:MEG8 is involved in ischemia stroke, however, its role in ischemia stroke remains unknown. The current research aimed to investigate the effects and mechanisms of MEG8 in ischemic stroke. Mouse brain microvascular endothelial cells (BMECs) were treated by oxygen-glucose deprivation (OGD). Then, the expressions of MEG8...

journal_title：Cellular and molecular neurobiology

authors： Sui S,Sun L,Zhang W,Li J,Han J,Zheng J,Xin H

更新日期：2020-07-05 00:00:00

abstract：:Symptoms like mental retardation, depression, and anxiety have been observed during aging. Almost similar phenotypes have been evident in patients having haploinsufficiency or mutations in Pax6, a transcriptional regulator. Since Pax6 regulates axon guidance, differentiation of neurons from glia, and neuronal migratio...

journal_title：Cellular and molecular neurobiology

authors： Tripathi R,Mishra R

更新日期：2012-03-01 00:00:00

abstract：:Accumulated evidence has shown that excessive reactive oxygen species (ROS) have been implicated in neuronal cell death related with various chronic neurodegenerative disorders. This study was designed to explore neuroprotective effects of ethyl acetate extract of Arctium lappa L. roots (EAL) on hydrogen peroxide (H2O...

journal_title：Cellular and molecular neurobiology

authors： Tian X,Guo LP,Hu XL,Huang J,Fan YH,Ren TS,Zhao QC

更新日期：2015-04-01 00:00:00