Guggulipid and nimesulide differentially regulated inflammatory genes mRNA expressions via inhibition of NF-kB and CHOP activation in LPS-stimulated rat astrocytoma cells, C6.

abstract：:Exposing bovine chromaffin cells to a single 5 ns, high-voltage (5 MV/m) electric pulse stimulates Ca(2+) entry into the cells via L-type voltage-gated Ca(2+) channels (VGCC), resulting in the release of catecholamine. In this study, fluorescence imaging was used to monitor nanosecond pulse-induced effects on intracel...

journal_title：Cellular and molecular neurobiology

authors： Craviso GL,Choe S,Chatterjee P,Chatterjee I,Vernier PT

更新日期：2010-11-01 00:00:00

abstract：:1. Synaptic vesicles (SVs) mediate fast regulated secretion of classical neurotransmitters. In order to perform their task SVs rely on a restrict set of membrane proteins. The mechanisms responsible for targeting these proteins to the SV membrane are still poorly understood. 2. Likewise, little is known about the intr...

journal_title：Cellular and molecular neurobiology

authors： Prado VF,Prado MA

更新日期：2002-12-01 00:00:00

abstract：:1. Aminoalkylindoles, typified by WIN 55212-2, bind to G protein-coupled cannabinoid receptors in brain. Although cannabinoids inhibit adenylyl cyclase in NG108-15 neuroblastoma x glioma hybrid cells, cannabinoid receptor binding in these cells has not been described previously. This study compares pharmacological cha...

journal_title：Cellular and molecular neurobiology

authors： Stark S,Pacheco MA,Childers SR

更新日期：1997-10-01 00:00:00

abstract：:1. The original concept of the ischemic penumbra surrounding a focus of dense cerebral ischemia is based on electrophysiological observations. In the cortex of baboons following middle cerebral artery occlusion, complete failure of the cortical evoked potential was observed at a cerebral blood flow (CBF) threshold lev...

journal_title：Cellular and molecular neurobiology

authors： Back T

更新日期：1998-12-01 00:00:00

abstract：:1. Compared to pineal N-acetyl transferase (NAT) activity, which exhibited a dramatic drop following acute light exposure at night, nocturnal rat pineal thyroxine type II 5'-deiodinase (5'-D) activity was minimally influenced by the same light exposure. The injection of cycloheximide, a potent inhibitor of protein syn...

journal_title：Cellular and molecular neurobiology

authors： Guerrero JM,Puig-Domingo M,Santana C,Menendez-Pelaez A,Gonzalez-Brito A,Reiter RJ

更新日期：1988-12-01 00:00:00

abstract：:The role of NO in epileptogenesis has been studied in different experimental models, and the reported results have been highly contradictory. The current study aimed to determine the role of NO in mechanisms of D: ,L: -homocysteine-thiolactone (H) induced seizures by testing the action of L: -arginine (NO precursor) a...

journal_title：Cellular and molecular neurobiology

authors： Hrncić D,Rasić-Marković A,Krstić D,Macut D,Djuric D,Stanojlović O

更新日期：2010-03-01 00:00:00

abstract：:1. Two giant peptidergic neurons, VD1 and RPD2, of the visceral ganglion and right parietal ganglion of Lymnaea stagnalis, respectively, play an important role in the modulation of complex physiological and behavioral adjustments that occur as a result of changes in O2 availability. 2. By cDNA cloning, we have identif...

journal_title：Cellular and molecular neurobiology

authors： Bogerd J,Van Kesteren RE,Van Heerikhuizen H,Geraerts WP,Veenstra J,Smit AB,Joosse J

更新日期：1993-04-01 00:00:00

abstract：:1. A lambda phage genomic DNA library for Limulus (L.) polyphemus brain was constructed using the AGEM-12 vector and the host strain KW251. 2. The primary library contained approximately 1.275 x 10(6) independent clones, increasing upon amplfication to 6.66 x 10(9) pfu/ml in a total volume of 58 ml. 3. A total of 28 c...

journal_title：Cellular and molecular neurobiology

authors： Wang Y,Cao Z,Reid EA,Newkirk RF,Ivy MT,Townsel JG

更新日期：2000-08-01 00:00:00

abstract：:1. Tau, which is a microtubule-associated protein, with mRNA targeted to the axon and growth cone, is involved in axonal elongation. During postnatal development in mouse, Tau expression in cerebellar granule cells is reduced afte the second postnatal week. The aim of this work was to study the regulation of the rate ...

journal_title：Cellular and molecular neurobiology

authors： Vilá-Ortiz GJ,Santa-Coloma TA,Carminatti H,Radrizzani M

更新日期：2001-10-01 00:00:00

abstract：:The original version of the article unfortunately contained an error in the unit of the protein concentrations under 'Stereotactic Intraparenchymal Injections' subsection in 'Methods' section. ...

journal_title：Cellular and molecular neurobiology

authors： Riabinska A,Zille M,Terzi MY,Cordell R,Nieminen-Kelhä M,Klohs J,Piña AL

更新日期：2020-07-01 00:00:00

abstract：:1. Innervation of the mammalian pineal gland is mainly sympathetic. Pineal synthesis of melatonin and its levels in the circulation are thought to be under strict adrenergic control of serotonin N-acetyltransferase (NAT). In addition, several putative pineal neurotransmitters modulate melatonin synthesis and secretion...

journal_title：Cellular and molecular neurobiology

authors： Laitinen JT,Laitinen KS,Kokkola T

更新日期：1995-04-01 00:00:00

abstract：:1. We studied the effects of three cytoskeleton-disrupting agents, colchicine (COL), vinblastine (VIN), cytochalasins, on the functional hemispheric expression of native muscarinic and acquired thyrotropin-releasing hormone receptors TRH-Rs). Responses in oocytes of common donors, which express M3-like receptors (M3Rs...

journal_title：Cellular and molecular neurobiology

authors： Matus-Leibovitch N,Gershengorn MC,Oron Y

更新日期：1993-12-01 00:00:00

abstract：:Transient forebrain ischemia and reperfusion induces delayed neuronal death (DND) in the hippocampal Cornu Ammonis 1 (CA1) subfield of stroke-prone spontaneously hypertensive rat (SHRSP). The vulnerability to DND is potentially related to the genetic susceptibility to stroke in this strain. To elucidate the mechanism ...

journal_title：Cellular and molecular neurobiology

authors： Daisu M,Hatta T,Sakurai-Yamashita Y,Nabika T,Moritake K

更新日期：2009-06-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a leading cause of death and long-term disability. Fucoidan, a sulfated polysaccharide extracted from brown algae, possesses potent anti-oxidative and anti-inflammatory effects. Considering TBI happens frequently in adults, especially in aged individuals, we herein sought to define the ...

journal_title：Cellular and molecular neurobiology

authors： Wang T,Zhu M,He ZZ

更新日期：2016-11-01 00:00:00

abstract：:1. The pathogenesis of diabetic neuropathy is a complex phenomenon, the mechanisms of which are not fully understood. Our previous studies have shown that the intracellular calcium signaling is impaired in primary and secondary nociceptive neurons in rats with streptozotocin (STZ)-induced diabetes. Here, we investigat...

journal_title：Cellular and molecular neurobiology

authors： Shutov L,Kruglikov I,Gryshchenko O,Khomula E,Viatchenko-Karpinski V,Belan P,Voitenko N

更新日期：2006-10-01 00:00:00

abstract：:Voltage-gated sodium channels are crucial mediators of neuronal damage in ischemic and excitotoxicity disease models. Fenamates have been reported to have anti-inflammatory properties following a decrease in prostaglandin synthesis. Several researches showed that fenamates appear to be ion channel modulators and poten...

journal_title：Cellular and molecular neurobiology

authors： Sun JF,Zhao MY,Xu YJ,Su Y,Kong XH,Wang ZY

更新日期：2020-11-01 00:00:00

abstract：:(1) A Little information exists on the distribution of Slit-Robo-GTPase activating proteins (srGAPs), particularly about their intracellular locations, which may provide further clues to their functions. The purpose of this study is to elucidate the expression patterns of the three srGAPs in wild-type rat brains at ad...

journal_title：Cellular and molecular neurobiology

authors： Yao Q,Jin WL,Wang Y,Ju G

更新日期：2008-02-01 00:00:00

abstract：:1. The possibility that a long-lasting neuronal activation regulates the expression of muscarinic cholinergic receptors was studied with three cultured neuronal cell lines. 2. Continuous depolarization of a subclone of the neuroblastoma-glioma NG108-15 hybrid cells with potassium chloride increased by 45-75% the numbe...

journal_title：Cellular and molecular neurobiology

authors： Simantov R,Levy R

更新日期：1989-03-01 00:00:00

abstract：:Although Butylphthalide (BP) has protective effects that reduce ischemia-induced brain damage and neuronal cell death, little is known about the precise mechanisms occurring during cerebral ischemia/reperfusion (I/R). Therefore, the aim of this study was to investigate the neuroprotective mechanisms of BP against isch...

journal_title：Cellular and molecular neurobiology

authors： Wen XR,Tang M,Qi DS,Huang XJ,Liu HZ,Zhang F,Wu J,Wang YW,Zhang XB,Guo JQ,Wang SL,Liu Y,Wang YL,Song YJ

更新日期：2016-10-01 00:00:00

abstract：:Spinal cord injury (SCI) remains a formidable challenge in the clinic. In the current study, we examined the effects of the TLX gene on the proliferation and neuronal differentiation of dermal multipotent stem cells (DMSCs) in vitro and the potential of these cells to improve SCI in rats in vivo. DMSCs were stably tra...

journal_title：Cellular and molecular neurobiology

authors： Wang T,Ren X,Xiong J,Zhang L,Qu J,Xu W

更新日期：2011-04-01 00:00:00

abstract：:Reactive microglia clustering around amyloid plaques in brain is a histopathological feature of Alzheimer's disease (AD) and reflects the contribution of neuroinflammation in AD pathogenesis. β-Amyloid peptide (Aβ) has been shown to induce a range of microglial responses including chemotaxis, cytotoxicity and inflamma...

journal_title：Cellular and molecular neurobiology

authors： Zhang X,Ye P,Wang D,Liu Y,Cao L,Wang Y,Xu Y,Zhu C

更新日期：2019-07-01 00:00:00

abstract：:Normokalemic periodic paralysis (normoPP) is a type of skeletal muscle function disorder which is characterized by paralysis attack with concomitant normal serum potassium level. We previously reported that R675Q mutation of human skeletal muscle voltage-gated sodium channel α subunit (SCN4A) may be the novel mutation...

journal_title：Cellular and molecular neurobiology

authors： Wu L,Zhang B,Kang Y,Wu W

更新日期：2014-07-01 00:00:00

abstract：:Reeler heterozygous mice (reln+/-) are seemingly normal but haplodeficient in reln, a gene implicated in autism. Structural/neurochemical alterations in the reln+/- brain are subtle and difficult to demonstrate. Therefore, the usefulness of these mice in translational research is still debated. As evidence implicated ...

journal_title：Cellular and molecular neurobiology

authors： Castagna C,Merighi A,Lossi L

更新日期：2019-08-01 00:00:00

abstract：:The degenerating muscle (dmu) mouse harbors a loss-of-function mutation in the Scn8a gene, which encodes the alpha subunit of the voltage-gated sodium channel (VGSC) Na(V)1.6. The distribution of c-Fos and c-Jun was examined in spinal and cranial motoneurons of the dmu mouse. In the cervical spinal cord, trigeminal mo...

journal_title：Cellular and molecular neurobiology

authors： Ichikawa H,Kano M,Shimizu Y,Suzuki T,Sawada E,Ono W,Chu LW,Côté PD

更新日期：2010-07-01 00:00:00

abstract：:1. Amphetamine-induced c-fos and egr-1 expression in the striatum was used as a model in which to study the effects of antisense oligodeoxynucleotides (ODNs) directed at c-fos. Using direct infusions of ODNs into the striata of animals we have demonstrated that c-fos antisense ODNs retain most of their biological acti...

journal_title：Cellular and molecular neurobiology

authors： Chiasson BJ,Armstrong JN,Hooper ML,Murphy PR,Robertson HA

更新日期：1994-10-01 00:00:00

abstract：:1. Differential regulation, by dexamethasone, of glucocorticoid receptor gene expression was studied in three different neuronal cultures derived from hypothalamus amygdala, and cerebral cortex. 2. Cellular glucocorticoid receptor (GR) mRNA concentration was measured by hybridization using a 32P-labeled RNA probe comp...

journal_title：Cellular and molecular neurobiology

authors： Pepin MC,Beaulieu S,Barden N

更新日期：1990-06-01 00:00:00

abstract：:We aim to develop a cultured cell model, to serve as a system with which the altered circadian phenotypes produced by the clock gene variations could be studied in vitro. Tau mutation, which shortens the circadian period of hamsters and mice, was introduced into the CK1epsilon locus of cultured Rat1-R12 cells by gene ...

journal_title：Cellular and molecular neurobiology

authors： Shimada H,Numazawa K,Sasaki T,Kato N,Ebisawa T

更新日期：2009-07-01 00:00:00

abstract：:The intention of this review is to emphasize the current knowledge about the extent and importance of the substances co-localized with magnocellular arginine vasopressin (AVP) and oxytocin (OXY) as potential candidates for the gradual clarification of their actual role in the regulation of hydromineral homeostasis. Ma...

journal_title：Cellular and molecular neurobiology

authors： Bundzikova J,Pirnik Z,Zelena D,Mikkelsen JD,Kiss A

更新日期：2008-12-01 00:00:00

abstract：:1. Wobbler mice suffer an autosomal recessive mutation producing severe motoneuron degeneration and dense astrogliosis, with increased levels of glial fibrillary acidic protein (GFAP) in the spinal cord and brain stem. They have been considered animal models of amyotrophic lateral sclerosis and infantile spinal muscul...

journal_title：Cellular and molecular neurobiology

authors： Gonzalez Deniselle MC,Gonzalez SL,Piroli GG,Lima AE,De Nicola AF

更新日期：1996-02-01 00:00:00

abstract：:Acute encephalopathy is a generic term for acute brain dysfunction occurring after infection. Acute encephalopathy induced by influenza virus results in high mortality, and most cases of influenza-associated encephalopathy (IAE) result in brain edema. Administration of diclofenac sodium (DCF), a non-steroidal anti-inf...

journal_title：Cellular and molecular neurobiology

authors： Asai H,Kakita H,Aoyama M,Nagaya Y,Saitoh S,Asai K

更新日期：2013-04-01 00:00:00