Effects of adrenocortical steroids on long-term potentiation in the limbic system: basic mechanisms and behavioral consequences.

abstract：:1. Retina-cell aggregate cultures expressed glutamate decarboxylase activity (L-glutamate 1-carboxylase; EC 4.1.1.15) as a function of culture differentiation. 2. Glutamic acid decarboxylase (GAD) activity was low in the initial phases of culture and increased eight-fold until culture day 7, remaining high up to day 1...

journal_title：Cellular and molecular neurobiology

authors： de Mello FG,Hokoç JN,Ventura AL,Gardino PF

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:The diagnosis of multiple sclerosis (MS) is still challenging recently due to the lack of a specific diagnostic test. Proteomics analysis was applied to biomarkers discovery and their pathways study. METHODS:First, the proteins of CSF from MS patients and control group were analyzed individually with 2D-DIGE...

journal_title：Cellular and molecular neurobiology

authors： Qin Z,Qin Y,Liu S

更新日期：2009-03-01 00:00:00

abstract：:1. Differential regulation, by dexamethasone, of glucocorticoid receptor gene expression was studied in three different neuronal cultures derived from hypothalamus amygdala, and cerebral cortex. 2. Cellular glucocorticoid receptor (GR) mRNA concentration was measured by hybridization using a 32P-labeled RNA probe comp...

journal_title：Cellular and molecular neurobiology

authors： Pepin MC,Beaulieu S,Barden N

更新日期：1990-06-01 00:00:00

abstract：:D-serine is synthesized by serine racemase (SR) and is a co-agonist at forebrain N-methyl-D-aspartate receptors (NMDARs). D-serine and SR are expressed primarily in neurons, but not in quiescent astrocytes. In this study, we examined the localization of D-serine and SR in the mouse striatum and the effects of genetica...

journal_title：Cellular and molecular neurobiology

authors： Takagi S,Puhl MD,Anderson T,Balu DT,Coyle JT

更新日期：2020-05-22 00:00:00

abstract：:Chromogranin A (CHGA) plays a fundamental role in the biogenesis of catecholamine secretory granules. Changes in storage and release of CHGA in clinical and experimental hypertension prompted us to study whether genetic variation at the CHGA locus might contribute to alterations in autonomic function, and hence hypert...

journal_title：Cellular and molecular neurobiology

authors： Chen Y,Rao F,Wen G,Gayen JR,Zhang K,Vaingankar SM,Biswas N,Mahata M,Friese RS,Fung MM,Salem RM,Nievergelt C,Bhatnagar V,Hook VY,Ziegler MG,Mahata SK,Hamilton BA,O'Connor DT

更新日期：2010-11-01 00:00:00

abstract：:The inactivation process of the calcium current (ICa) was investigated in a molluscan neuron which was perfused intracellularly and voltage-clamped using a suction pipette technique. The decay phase of the ICa contained a very slowly inactivated component (persistent inward current; PIC). The decay time constant of th...

journal_title：Cellular and molecular neurobiology

authors： Oyama Y,Akaike N,Nishi K

更新日期：1986-03-01 00:00:00

abstract：:1. The effect of transient forebrain ischemia on endothelin-1 (ET-1) and endothelin-3 (ET-3) production in the hippocampus of stroke-prone spontaneously hypertensive rats (SHRSPs) was investigated using immunohistochemical techniques. 2. In SHRSPs subjected to 10-min bilateral carotid occlusion, neuronal degeneration ...

journal_title：Cellular and molecular neurobiology

authors： Yamashita K,Kataoka Y,Niwa M,Shigematsu K,Himeno A,Koizumi S,Taniyama K

更新日期：1993-02-01 00:00:00

abstract：:ATP13A4 is a member of the subfamily of P5-type ATPases. P5-type ATPases are the least studied of the P-type ATPase subfamilies with no ion specificities assigned to them. In order to elucidate ATP13A4 function, we studied the protein's subcellular localization and tested whether it is involved in calcium regulation. ...

journal_title：Cellular and molecular neurobiology

authors： Vallipuram J,Grenville J,Crawford DA

更新日期：2010-03-01 00:00:00

abstract：:The contribution of axonal activity to the ionic currents which generate bursting pacemaker activity was studied by using the two-electrode voltage-clamp technique in Aplysia bursting neuron somata in conjunction with intraaxonal voltage recordings. Depolarizing voltage-clamp pulses applied to bursting cell somata tri...

journal_title：Cellular and molecular neurobiology

authors： Kramer RH

更新日期：1986-09-01 00:00:00

abstract：:Green fluorescent protein (GFP) gene was transfected and expressed in murine embryonic stem (ES) cells under the control of the astrocyte-specific glial fibrillary acidic protein (GFAP) promoter. Stably transfected cells were characterized by immunohistochemistry and by fluorescence microscopy. Cells containing GFP we...

journal_title：Cellular and molecular neurobiology

authors： Tang F,Shang K,Wang X,Gu J

更新日期：2002-02-01 00:00:00

abstract：:Abeta accumulation, a hallmark of Alzheimer's disease, promotes the disease progress in multiple facets. Abeta is formed through amyloidogenic cleavage pathway of amyloid precursor protein (APP). Production of Abeta can be decreased via activation of 5-HT2C receptor, which enhances alternative APP non-amyloidogenic cl...

journal_title：Cellular and molecular neurobiology

authors： Tian XL,Yu LH,Li WQ,Hu Y,Yin M,Wang ZJ

更新日期：2015-04-01 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by deposition of beta-amyloid peptides (Aβ) and progressive loss of neurons. Neural stem/progenitor cells (NSPCs) can proliferate and produce immature neurons even in the brain of AD patients. However, Aβ42 significantly decreased the expression of RhoC in NSPCs during the co-...

journal_title：Cellular and molecular neurobiology

authors： Zhang C,Ge X,Lok K,Zhao L,Yin M,Wang ZJ

更新日期：2014-04-01 00:00:00

abstract：:1. Gonadotropin-releasing hormone (GnRH) was originally isolated as a hypothalamic peptide hormone that regulates the reproductive system by stimulating the release of gonadotropins from the anterior pituitary. However, during evolution the peptide was subject to gene duplication and structural changes, and multiple m...

journal_title：Cellular and molecular neurobiology

authors： King JA,Millar RP

更新日期：1995-02-01 00:00:00

abstract：:1. Interleukin-10 (IL-10) has a wide range of activities in the immune system such as modulation of interferon-gamma (IFN-gamma) and antibody production. The neuropeptide hormone corticotropin (ACTH) has similar activities, suggesting that a bidirectional communication mechanism operates between the immune and the neu...

journal_title：Cellular and molecular neurobiology

authors： Hughes TK,Cadet P,Rady PL,Tyring SK,Chin R,Smith EM

更新日期：1994-02-01 00:00:00

abstract：:As a novel cell cycle inhibitor, PHB2 controls the G1/S transition in cycling cells in a complex manner. Its aberrant expression is closely related to cell carcinogenesis. While its expression and role in peripheral nervous system lesion and repair were still unknown. Here, we performed an acute sciatic nerve crush (S...

journal_title：Cellular and molecular neurobiology

authors： Long L,Huang Y,Wu H,Luan W,Zhang Q,Wen H,Ding T,Wang Y

更新日期：2013-07-01 00:00:00

abstract：:1. Effects of pentosan polysulfate (PPS) and the structurally related sulfated polyanions dextran sulfate, fucoidan, and heparin on the scavenger receptor-mediated and fluidphase endocytosis in GP8 immortalized rat brain endothelial cells were investigated. 2. Using 1,1'-dioctadecyl-3,3,3,3'-tetramethylindocarboxyamin...

journal_title：Cellular and molecular neurobiology

authors： Deli MA,Abrahám CS,Takahata H,Katamine S,Niwa M

更新日期：2000-12-01 00:00:00

abstract：:Established cancer cell lines are routinely used to study cancer. Several factors such as serial passage may affect the reproducibility of experiments with cancer cell lines, but few researches focused on these changes. In the present study, different morphology and decreased tumorigenicity were observed in late passa...

journal_title：Cellular and molecular neurobiology

authors： Zeng Y,Wang X,Wang J,Yi R,Long H,Zhou M,Luo Q,Zhai Z,Song Y,Qi S

更新日期：2018-08-01 00:00:00

abstract：:Although it is known that brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal survival and differentiation, its effect on lipid homeostasis is poorly understood. To understand them, we here investigated the effect of BDNF on the fatty acid composition of primary neurons. A detailed analysis of t...

journal_title：Cellular and molecular neurobiology

authors： Suzuki S,Hongli Q,Okada A,Kasama T,Ohta K,Warita K,Tanaka K,Miki T,Takeuchi Y

更新日期：2012-11-01 00:00:00

abstract：:Matrix metalloproteinase-1 (MMP-1), a member of the matrix metalloproteinases family, plays an integral role in extracellular matrix degradation and has been reportedly involved in the regulation of the brain or spinal cord traumatic neurovascular remodeling. Although the critical involvement of MMP-1 in the metastasi...

journal_title：Cellular and molecular neurobiology

authors： Zhou Y,Cui Z,Xia X,Liu C,Zhu X,Cao J,Wu Y,Zhou L,Ben Z,Song Y,Zhang H,Zhang D

更新日期：2014-11-01 00:00:00

abstract：:The hypernociceptive role played by the chemokine CCL2, and its main receptor, CCR2, in pathological settings is being increasingly recognized. We aimed to characterize the involvement of spinal CCL2 in the hyperalgesia due to the intratibial inoculation of fibrosarcoma NCTC 2472 cells in mice. The intrathecal (i.t.) ...

journal_title：Cellular and molecular neurobiology

authors： Pevida M,González-Rodríguez S,Lastra A,García-Suárez O,Hidalgo A,Menéndez L,Baamonde A

更新日期：2014-01-01 00:00:00

abstract：:Shen-Zhi-Ling (SZL) is a Chinese medicine formulated from a Kai-Xin-San decoction that is commonly used to treat depression caused by dual deficiencies in the heart and spleen. However, the underlying mechanisms remain unclear. We investigated biological changes in depression patients (DPs) exhibiting antidepressant r...

journal_title：Cellular and molecular neurobiology

authors： Chen C,Hu Y,Dong XZ,Zhou XJ,Mu LH,Liu P

更新日期：2018-07-01 00:00:00

abstract：:Thymosin-beta4 (Tbeta4) is a major actin monomer-binding peptide in mammalian tissues and plays a crucial role in the nervous system in synaptogenesis, neuronal survival and migration, axonal growth, and plastic changes of dendritic spines. However, it is unknown whether Tbeta4 is also involved in challenges with exte...

journal_title：Cellular and molecular neurobiology

authors： Yang H,Cui GB,Jiao XY,Wang J,Ju G,You SW

更新日期：2010-01-01 00:00:00

abstract：:Microelectrophoretic application of sex hormones onto pineal cells in guinea pigs has shown different responses in pregnant females as compared to males. In pregnant females estrone caused excitation in 74% of the cells tested, while progesterone and testosterone, prolactin, and HCG were inhibitory in a majority of th...

journal_title：Cellular and molecular neurobiology

authors： Semm P,Demaine C,Vollrath L

更新日期：1981-09-01 00:00:00

abstract：:Inhibitory mechanism of cerebellum epileptic activity can be involved depending on the intensity and frequency of seizure convulsions. N-methyl-D-aspartate receptors (NMDARs) play key roles in excitatory synaptic transmission and have been implicated in neurological disorders: in cerebellum, they have specific charact...

journal_title：Cellular and molecular neurobiology

authors： Girardi E,Auzmendi J,Charó N,Gori MB,Castro M

更新日期：2010-10-01 00:00:00

abstract：:Hypothermia treatment is one of the neuroprotective strategies that improve neurological outcomes effectively after brain damage. Minimally invasive surgery (MIS) has been an important treatment of intracerebral hemorrhage (ICH). Herein, we evaluated the neuroprotective effect and mechanism of MIS joint local cooling ...

journal_title：Cellular and molecular neurobiology

authors： Liu XC,Jing LY,Yang MF,Wang K,Wang Y,Fu XY,Fang J,Hou YJ,Sun JY,Li DW,Zhang ZY,Mao LL,Tang YM,Fu XT,Fan CD,Yang XY,Sun BL

更新日期：2016-07-01 00:00:00

abstract：:Both sex and steroid hormones are important to consider in human ischemic stroke and its experimental models. Stroke initiates a cascade of changes that lead to neural cell death, but also activates endogenous protective processes that counter the deleterious consequences of ischemia. Steroids may be part of these cer...

journal_title：Cellular and molecular neurobiology

authors： Guennoun R,Zhu X,Fréchou M,Gaignard P,Slama A,Liere P,Schumacher M

更新日期：2019-05-01 00:00:00

abstract：:Cerebral cavernous malformations (CCM) are vascular malformations associated with abnormally dilated blood vessels and leaky capillaries that often result in hemorrhages. Despite recent advances, precise understanding of the cellular and molecular mechanism leading to the pathogenesis of CCM remains elusive. Emerging ...

journal_title：Cellular and molecular neurobiology

authors： Kar S,Bali KK,Baisantry A,Geffers R,Hartmann C,Samii A,Bertalanffy H

更新日期：2018-10-01 00:00:00

abstract：:1. Several intrinsically disordered proteins (IDPs) play principal role in the neurodegenerative processes of various types. Among them, alpha-synuclein is involved in Parkinson's disease, prion protein in transmissible spongiform encephalopathies, and tau protein in Alzheimer's disease (AD) and related tauopathies. N...

journal_title：Cellular and molecular neurobiology

authors： Skrabana R,Sevcik J,Novak M

更新日期：2006-10-01 00:00:00

abstract：AIM:A fraction of vesicles in cells treated with hypertonic solution exhibit multiple dense cores and this is enhanced by treatment with L-3,4-dihydroxyphenylalanine (L-DOPA). These cells were examined to determine if the multicore vesicles are the product of endocytosis or homotypic fusion. METHODS:Electron microscop...

journal_title：Cellular and molecular neurobiology

authors： Sombers LA,Maxson MM,Ewing AG

更新日期：2007-08-01 00:00:00

abstract：:To clarify the role of angiotensin II (Ang II) in the regulation of sensory signaling, we studied the effect of subpressor dose (150 ng/kg/min) of Ang II on pain-related behavior in relation with neuronal injury and activation of satellite glial cells (SGCs) in the dorsal root ganglia (DRGs) after chronic constriction...

journal_title：Cellular and molecular neurobiology

authors： Pavel J,Oroszova Z,Hricova L,Lukacova N

更新日期：2013-07-01 00:00:00