Serine Racemase Expression by Striatal Neurons.

abstract：:The sympathoneural and the adrenomedullary systems are involved in regulation of immune processes. Their impairment has been suggested in patients with rheumatoid arthritis (RA). In this study, sympathetic response to orthostasis was evaluated in 22 RA females with <40 years of age and in 15 matched healthy controls. ...

journal_title：Cellular and molecular neurobiology

authors： Vlcek M,Rovensky J,Eisenhofer G,Radikova Z,Penesova A,Kerlik J,Imrich R

更新日期：2012-07-01 00:00:00

abstract：:1. The central nervous systems (CNS) of males and females differ in the control mechanisms for the release of gonadotropins from the anterior pituitary gland as well as the capacity to display sex specific behaviors. 2. In guinea pigs and monkeys, these differences are organized through the actions of prenatal androge...

journal_title：Cellular and molecular neurobiology

authors： Resko JA,Roselli CE

更新日期：1997-12-01 00:00:00

abstract：:1. Angiotensin II receptors have been studied by quantitative autoradiography in selected brain areas of young (2-week-old) and adult (8-week-old) rats. 2. In young rats, angiotensin II receptors were present in brain areas which did not express receptors in the adult brain, such as thalamic nuclei, cortical areas, an...

journal_title：Cellular and molecular neurobiology

authors： Tsutsumi K,Saavedra JM

更新日期：1991-04-01 00:00:00

abstract：:1. Melanin-concentrating hormone (MCH)-containing neurons within the lateral hypothalamus affect a broad spectrum of physiological and behavioral processes. The aim of this study was to examine a differentiation of rat MCH neurons dependent on their functionally related projections to the intermediolateral column (IML...

journal_title：Cellular and molecular neurobiology

authors： Harthoorn LF

更新日期：2007-02-01 00:00:00

abstract：:Glioma stem cells (GSCs) are thought to be critical for resistance to radiotherapy and chemotherapy and for tumor recurrence after surgery in glioma patients. Identification of new therapeutic strategies that can target GSCs may thus be critical for improving patient survival. MicroRNAs (miRNAs) are small non-coding R...

journal_title：Cellular and molecular neurobiology

authors： Chen L,Chen XR,Chen FF,Liu Y,Li P,Zhang R,Yan K,Yi YJ,Xu ZM,Jiang XD

更新日期：2013-07-01 00:00:00

abstract：:The anorexigenic molecule nesfatin-1 has recently been taken as a potential mood regulator, but the potential mechanisms remain unknown. Results of our previous study have demonstrated that nesfatin-1 could induce anxiety- and depression-like behaviors in rats, accompanied by the hyperactivity of the hypothalamic-pitu...

journal_title：Cellular and molecular neurobiology

authors： Chen Z,Xu YY,Ge JF,Chen FH

更新日期：2018-04-01 00:00:00

abstract：:In our previous research, the formation and development of age-related cataract (ARC) is associated with DNA hypermethylation of some genes in lens epithelial cells (LECs). This study aimed to investigate the expression profile of DNA methylation- and transcriptional repression-associated genes in LECs of ARC. The exp...

journal_title：Cellular and molecular neurobiology

authors： Wang Y,Zhang G,Kang L,Guan H

更新日期：2017-04-01 00:00:00

abstract：:1. Transient forebrain ischemia in adult rats, induced by 10 min of bilateral carotid occlusion and an arterial hypotension of 40 mmHg, caused substantial damage not only to CA-1 neurons in hippocampus but also to epithelial cells in lateral ventricle choroid plexus. 2. When transient forebrain ischemia was followed b...

journal_title：Cellular and molecular neurobiology

authors： Johanson CE,Palm DE,Primiano MJ,McMillan PN,Chan P,Knuckey NW,Stopa EG

更新日期：2000-04-01 00:00:00

abstract：:Acetylcholine (ACh) responses were elicited by ionophoresis from neurons, located in the medial pontine reticular formation, which were antidromically identified as having axons projecting in the reticulospinal tracts. Most neurons were silent at rest and could be caused to discharge at a regular, slow rate by a const...

journal_title：Cellular and molecular neurobiology

authors： Greene RW,Carpenter DO

更新日期：1981-12-01 00:00:00

abstract：AIM:A fraction of vesicles in cells treated with hypertonic solution exhibit multiple dense cores and this is enhanced by treatment with L-3,4-dihydroxyphenylalanine (L-DOPA). These cells were examined to determine if the multicore vesicles are the product of endocytosis or homotypic fusion. METHODS:Electron microscop...

journal_title：Cellular and molecular neurobiology

authors： Sombers LA,Maxson MM,Ewing AG

更新日期：2007-08-01 00:00:00

abstract：:Ac2-26, a mimetic peptide of Annexin-A1, plays a vital role in the anti-inflammatory response mediated by astrocytes. In this study, we aimed to explore the underlying mechanisms of Ac2-26-mediated anti-inflammatory effect. Specifically, we investigated the inhibitory effects of Ac2-26 on lipopolysaccharide (LPS)-indu...

journal_title：Cellular and molecular neurobiology

authors： Luo Z,Wang H,Fang S,Li L,Li X,Shi J,Zhu M,Tan Z,Lu Z

更新日期：2020-05-01 00:00:00

abstract：:1. We studied the effect of isolation stress in 3- and 12-month-old rats individually housed in metabolic cages for 7 days. Urine (24 hr) was collected daily from one group of animals of each age. The other group was tested in an open field and on a hot plate on days 1 and 7. 2. Total deambulation in the open-field te...

journal_title：Cellular and molecular neurobiology

authors： Gil MC,Aguirre JA,Lemoine AP,Segura ET,Barontini M,Armando I

更新日期：1999-10-01 00:00:00

abstract：:1. Five drugs with the predominant pharmacologic effect of inhibiting the neuronal reuptake of serotonin are available worldwide for clinical use. This class of psychoactive drugs, known as selective serotonin reuptake inhibitors (SSRIs), is comprised of fluoxetine, sertraline, paroxetine, fluvoxamine, and citalopram....

journal_title：Cellular and molecular neurobiology

authors： DeVane CL

更新日期：1999-08-01 00:00:00

abstract：:1. Compared to pineal N-acetyl transferase (NAT) activity, which exhibited a dramatic drop following acute light exposure at night, nocturnal rat pineal thyroxine type II 5'-deiodinase (5'-D) activity was minimally influenced by the same light exposure. The injection of cycloheximide, a potent inhibitor of protein syn...

journal_title：Cellular and molecular neurobiology

authors： Guerrero JM,Puig-Domingo M,Santana C,Menendez-Pelaez A,Gonzalez-Brito A,Reiter RJ

更新日期：1988-12-01 00:00:00

abstract：:1. Nitric oxide (NO) is thought to play a neuromodulatory role in the nervous system of vertebrate and invertebrate species. In the hornworm Manduca sexta, NO-mediated signaling has been implicated in behavioral and developmental processes, but its exact function in neurons is unknown. In this study, we identify speci...

journal_title：Cellular and molecular neurobiology

authors： Zayas RM,Trimmer BA

更新日期：2007-03-01 00:00:00

abstract：:Hippocampal structures are a major target for adrenal steroid hormones, and hence these neural regions are some of the most likely mediators of the effects of adrenocortical steroids on behavior. Memory disturbance, in particular biasing toward negative contents, are part of the symptomatology presented by depressive ...

journal_title：Cellular and molecular neurobiology

authors： Dubrovsky B,Gijsbers K,Filipini D,Birmingham MK

更新日期：1993-08-01 00:00:00

abstract：:The stimulation of peripheral opioid receptors counteracts thermal hyperalgesia produced by the intratibial inoculation of NCTC 2472 cells in mice, through the activation of the nitric oxide/cGMP/ATP-sensitive K+-channels (NO/cGMP/K(+) (ATP)) cascade (Menéndez et al. 2007, Neuropharmacology 53:71-80). We aimed to eluc...

journal_title：Cellular and molecular neurobiology

authors： Curto-Reyes V,Juárez L,García-Pérez E,Fresno MF,Hidalgo A,Menéndez L,Baamonde A

更新日期：2008-11-01 00:00:00

abstract：:Rosmarinic acid (RA) is a natural polyphenolic compound with a well-documented neuroprotective effect mainly associated with its anti-inflammatory and antioxidant activities. Recently, our research group developed and optimized chitosan-coated RA nanoemulsions (RA CNE) intended to be used for nasal delivery as a new p...

journal_title：Cellular and molecular neurobiology

authors： Fachel FNS,Dal Prá M,Azambuja JH,Endres M,Bassani VL,Koester LS,Henriques AT,Barschak AG,Teixeira HF,Braganhol E

更新日期：2020-01-01 00:00:00

abstract：:1. Spatio-temporal changes in phosphorylated (pNFP) and nonphosphorylated (npNFP) neurofilament proteins were assessed immunocytochemicaly in adult rat cerebellum, 2-30 days following unilateral injection of kainic acid (KA) or physiological saline (s.c.). 2. Analysis of the staining intensity and pattern demonstrated...

journal_title：Cellular and molecular neurobiology

authors： Milenkovic I,Filipovic R,Nedeljkovic N,Pekovic S,Culic M,Rakic L,Stojiljkovic M

更新日期：2004-06-01 00:00:00

abstract：:Since gonadal female hormones act on and protect neurons, it is well known that the female brain is less vulnerable to stroke or other brain insults than the male brain. Although glial functions have been shown to affect the vulnerability of the brain, little is known if such a sex difference exists in glia, much less...

journal_title：Cellular and molecular neurobiology

authors： Morizawa Y,Sato K,Takaki J,Kawasaki A,Shibata K,Suzuki T,Ohta S,Koizumi S

更新日期：2012-08-01 00:00:00

abstract：:ERK pathway plays a critical role in the cellular adaptive responses to environmental changes. Stressful conditions can induce the activation of activate ERK, and its downstream targets, CREB and c-fos, in neural cells. Exposure to opioids has the same effect. In this study, we investigated the effects of morphine-ind...

journal_title：Cellular and molecular neurobiology

authors： Haghparast A,Fatahi Z,Alamdary SZ,Reisi Z,Khodagholi F

更新日期：2014-03-01 00:00:00

abstract：:1. Data obtained studying permeability characteristics of single Deiters' membranes in a microchamber system show that intracellular GABA can activate chloride in-->out passage with a GABAA pharmacology. 2. The overall data suggest the presence of a chloride extrusion pump in these neurons based on intracellular GABA ...

journal_title：Cellular and molecular neurobiology

authors： Rapallino MV,Cupello A,Hydén H

更新日期：1999-12-01 00:00:00

abstract：:Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by the selective loss of nigrostriatal dopaminergic neurons. However, the molecular pathways leading to the dopaminergic neuron degeneration have remained obscure until recently. Reports demonstrated that reduction of b...

journal_title：Cellular and molecular neurobiology

authors： Yuan Y,Sun J,Zhao M,Hu J,Wang X,Du G,Chen NH

更新日期：2010-08-01 00:00:00

abstract：:We provide a comprehensive review of the available evidence on the pathophysiological implications of genetic variants in the human trace amine-associated receptor (TAAR) superfamily. Genes coding for trace amine-associated receptors (taars) represent a multigene family of G-protein-coupled receptors, clustered to a s...

journal_title：Cellular and molecular neurobiology

authors： Rutigliano G,Zucchi R

更新日期：2020-03-01 00:00:00

abstract：:Intrachain disulfide bond formation among the cysteine thiols of SNAP-25, a component of the SNARE protein complex required for neurotransmitter release, has been hypothesized to link oxidative stress and inhibition of synaptic transmission. However, neither the availability in vivo of SNAP-25 thiols, which are known ...

journal_title：Cellular and molecular neurobiology

authors： Foley TD,Clark AR,Stredny ES,Wierbowski BM

更新日期：2012-03-01 00:00:00

abstract：:Consisting of a fragment of ACTH(4-7) and C-terminal PGP tripeptide, the polypeptide Semax is successfully used for acute stroke therapy. Previous experiments showed rapid induction of Bdnf, Ngf, and TrkB expression in intact rat hippocampus following Semax treatment. To investigate the mRNA expression of neurotrophin...

journal_title：Cellular and molecular neurobiology

authors： Dmitrieva VG,Povarova OV,Skvortsova VI,Limborska SA,Myasoedov NF,Dergunova LV

更新日期：2010-01-01 00:00:00

abstract：:MicroRNAs are small non-coding RNAs which mediate post-transcriptional gene regulation. Recently, microRNAs have also been found to be localized to the extracellular space, often encapsulated in secreted extracellular vesicles (EVs). This tandem of EVs and tissue-specific expressed/secreted microRNAs that can be taken...

journal_title：Cellular and molecular neurobiology

authors： Bronisz A,Godlewski J,Chiocca EA

更新日期：2016-04-01 00:00:00

abstract：:(1) This study was to evaluate the anti-cholinesterase (ChE), cognition enhancing and neuroprotective effects of FS-0311, a bis-huperzine B derivative. (2) ChE activity was evaluated using a spectrophotometric method. Cognitive deficits in mice were induced by scopolamine or transient brain ischemia and reperfusion. W...

journal_title：Cellular and molecular neurobiology

authors： Wang ZF,Yan J,Fu Y,Tang XC,Feng S,He XC,Bai DL

更新日期：2008-02-01 00:00:00

abstract：:1. The analogies between the processing of amyloid precursor protein (APP) and other transmembrane sterol regulatory element binding proteins (SREBPs) inspired us to conduct further studies on whether beta-amyloid (Abeta) affects aromatase by interacting with APP and SREBP. 2. In this study, cultured human neuroblasto...

journal_title：Cellular and molecular neurobiology

authors： Kelicen P,Nordberg A

更新日期：2006-05-01 00:00:00

abstract：:The present study was undertaken to evaluate whether estrogen deprivation might lead to mitochondrial alteration of hippocampal neurons of ovariectomized (OVX) rats, and to evaluate the protective effect of estrogen and phytoestrogen on the mitochondrial alteration. First, OVX rats were used to mimic the pathologic ch...

journal_title：Cellular and molecular neurobiology

authors： Xu XW,Shi C,He ZQ,Ma CM,Chen WH,Shen YP,Guo Q,Shen CJ,Xu J

更新日期：2008-09-01 00:00:00