The effects of sex hormones, prolactin, and chorionic gonadotropin on pineal electrical activity in guinea pigs.

Abstract:

:Microelectrophoretic application of sex hormones onto pineal cells in guinea pigs has shown different responses in pregnant females as compared to males. In pregnant females estrone caused excitation in 74% of the cells tested, while progesterone and testosterone, prolactin, and HCG were inhibitory in a majority of the cells tested, while progesterone and testosterone, prolactin, and HCG were inhibitory in a majority of the cells. In contrast, in males estrone caused excitation of only 19% but inhibition of 37%. A smaller percentage of cells was inhibited by progesterone, while the predominant response to testosterone was excitation. These results suggest that the pineal gland may be under a feedback control.

journal_name

Cell Mol Neurobiol

authors

Semm P,Demaine C,Vollrath L

doi

10.1007/BF00710681

subject

Has Abstract

pub_date

1981-09-01 00:00:00

pages

259-69

issue

3

eissn

0272-4340

issn

1573-6830

journal_volume

1

pub_type

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