Abstract:
:Pseudorabies virus (PrV) as a neuronal tracer was microinjected into the concave surface of the puppy's left pinna to establish the morphological basis of somato-visceral linkage. The virus infected neurons were detected by FITC conjugated with polyclonal swine anti-PrV serum. Labelled neurons were localized in: (1) the trigeminal, geniculate and superior vagal ganglia; (2) the subnucleus caudalis of the spinal trigeminal nucleus; (3) the intermediolateral column (IML) of the thoracolumbar segments and (4) the sympathetic chain ganglia. Present results suggest that when injected into the peripheral nerves, PrV was retrogradely transported to the nerve cell bodies located in the respective sensory ganglia. From the first order sensory neurons, the virus would self-replicate and was transported trans-synaptically via the brainstem nuclei and IML to reach the neurons in the sympathetic ganglia.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Chien CH,Shieh JY,Liao MH,Ling EA,Wen CYdoi
10.1016/s0168-0102(97)00129-6subject
Has Abstractpub_date
1998-02-01 00:00:00pages
169-75issue
2eissn
0168-0102issn
1872-8111pii
S0168-0102(97)00129-6journal_volume
30pub_type
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