Neuronal connections between the auricular skin and the sympathetic pre- and postganglionic neurons of the dog as studied by using pseudorabies virus.

Abstract:

:Pseudorabies virus (PrV) as a neuronal tracer was microinjected into the concave surface of the puppy's left pinna to establish the morphological basis of somato-visceral linkage. The virus infected neurons were detected by FITC conjugated with polyclonal swine anti-PrV serum. Labelled neurons were localized in: (1) the trigeminal, geniculate and superior vagal ganglia; (2) the subnucleus caudalis of the spinal trigeminal nucleus; (3) the intermediolateral column (IML) of the thoracolumbar segments and (4) the sympathetic chain ganglia. Present results suggest that when injected into the peripheral nerves, PrV was retrogradely transported to the nerve cell bodies located in the respective sensory ganglia. From the first order sensory neurons, the virus would self-replicate and was transported trans-synaptically via the brainstem nuclei and IML to reach the neurons in the sympathetic ganglia.

journal_name

Neurosci Res

journal_title

Neuroscience research

authors

Chien CH,Shieh JY,Liao MH,Ling EA,Wen CY

doi

10.1016/s0168-0102(97)00129-6

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

169-75

issue

2

eissn

0168-0102

issn

1872-8111

pii

S0168-0102(97)00129-6

journal_volume

30

pub_type

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