Abstract：
:Whole-cell patch-clamp recordings were undertaken to characterize and compare the membrane properties of deep dorsal horn neurons in transverse slices of rat lumbar spinal cord in two age groups, postnatal days (P) 3-6 and 9-16. In both age groups, significant correlations were observed between membrane time constant and cell resistance and between action potential height and its duration at half-maximal amplitude. Cell resistance and action potential half-width values were lower in the P9-16 age group. Neurons were divided into four categories based on their firing properties in response to intracellular current injection: single spike, phasic firing, repetitive firing, and delayed firing. The distribution of neurons within these categories was similar in both age groups which suggests that the firing properties of deep dorsal horn neurons are functionally differentiated at an early postnatal age.
journal_name
Brain Resjournal_title
Brain researchauthors
Hochman S,Garraway SM,Pockett Sdoi
10.1016/s0006-8993(97)00578-7subject
Has Abstractpub_date
1997-09-05 00:00:00pages
214-9issue
2eissn
0006-8993issn
1872-6240pii
S0006-8993(97)00578-7journal_volume
767pub_type
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