Neuropeptides derived from prosomatostatin that do not contain the somatostatin-14 sequence.

abstract：:Since it has been proposed that oxidized protein accumulation plays a critical role in brain aging, we have investigated their contents in synaptic mitochondria from five age groups of mice. Protein carbonyl content in synaptic mitochondria showed a significant positive correlation with age (r = 0.95, P = 0.01). A lin...

journal_title：Brain research

authors： Martinez M,Hernández AI,Martínez N,Ferrándiz ML

更新日期：1996-08-26 00:00:00

abstract：:Acupuncture is widely used to relieve pain; however, the mechanism underlying electroacupuncture analgesia (EAA) during inflammatory pain is unclear. We investigated whether endogenous peripheral opioid receptors participated in EAA during hyperalgesia elicited by carrageenan-induced inflammation. Moreover, we investi...

journal_title：Brain research

authors： Taguchi R,Taguchi T,Kitakoji H

更新日期：2010-10-08 00:00:00

abstract：:Recent work in our laboratory has demonstrated that spontaneous or evoked climbing fiber inputs are associated with an increased responsiveness of Purkinje cells to mossy fiber inputs activated by natural peripheral stimuli. These experiments were designed to test the hypothesis that this increased responsiveness occu...

journal_title：Brain research

authors： Ebner TJ,Bloedel JR

更新日期：1984-08-20 00:00:00

abstract：:We examined the in vitro effects of neurotransmitters, high KCl as well as sialic acid-containing compounds (GM1; SC) on transglutaminase (TG) activity in isolated superior cervical ganglia (SCG) one week after denervation or axotomy. Following denervation, TG activity in SCG decreased to 83% of the unoperated control...

journal_title：Brain research

authors： Ando M,Kunii S,Tatematsu T,Nagata Y

更新日期：1993-02-26 00:00:00

abstract：:About 45% of the serotonergic raphe neurons are reported to express nerve growth factor (NGF) receptors. We therefore investigated whether selective serotonergic lesions of the median or dorsal raphe nuclei are associated with changes in NGF protein levels of the brain and whether the loss of serotonergic function alt...

journal_title：Brain research

authors： Hellweg R,Thomas H,Arnswald A,von Richthofen S,Kay S,Fink H,Morgenstern R,Hörtnagl H

更新日期：2001-07-13 00:00:00

abstract：:The hippocampus plays an important role in learning and memory and possibly contributes to the formation of pain-related memory and emotional responses. However, there is currently little data linking the hippocampus to neuropathic pain. It has been reported that NF-κB is an important regulatory factor in memory conso...

journal_title：Brain research

authors： Chou CW,Wong GT,Lim G,McCabe MF,Wang S,Irwin MG,Mao J

更新日期：2011-03-10 00:00:00

abstract：:Previous neuroimaging studies provided evidence that visual mental imagery relies, in part, on the primary visual cortex. We hypothesized that, analogous to the finding that motor imagery increases the excitability of motor cortex, visual imagery should increase visual cortex excitability, as indexed by a decrease in ...

journal_title：Brain research

authors： Sparing R,Mottaghy FM,Ganis G,Thompson WL,Töpper R,Kosslyn SM,Pascual-Leone A

更新日期：2002-05-31 00:00:00

abstract：:Pretreatment with scopolamine, 3 mg/kg, prevented the acquisition of a passive avoidance task in rats. These amnesic effects of scopolamine could largely be overcome by treatment with 100 mg/kg of the nootropic drug piracetam. In order to identify the brain structures involved, the effects of these drugs on regional e...

journal_title：Brain research

authors： Piercey MF,Vogelsang GD,Franklin SR,Tang AH

更新日期：1987-10-20 00:00:00

abstract：:The effects of 17 beta-estradiol benzoate (EB), ethynodioldiacetate and ovine prolactin on dopamine (DA) turnover have been studied. As an index for a change in turnover, differences in DA depletion following tyrosine hydroxylase inhibition with alpha-methyl-tyrosine methylester were observed. DA was measured by means...

journal_title：Brain research

authors： Wiesel FA,Fuxe K,Hökfelt T,Agnati LF

更新日期：1978-06-16 00:00:00

abstract：:Structural and functional alterations of the putamen have been reported in patients with attention deficit hyperactivity disorder (ADHD), but the functional relationships between this area and other brain regions are seldom explored. In the present study, seed-based correlation analyses were performed in the resting-s...

journal_title：Brain research

authors： Cao X,Cao Q,Long X,Sun L,Sui M,Zhu C,Zuo X,Zang Y,Wang Y

更新日期：2009-12-15 00:00:00

abstract：:Neurointermediate lobes of rats comprise elements which, when excited in vitro, bring about an inhibition of the release of melanocyte stimulating hormone (MSH). Superfusion of neurointermediate lobes of intact donor rats with medium containing 45 mM K+ induced a stimulation of the release of oxytocin, arginine-vasopr...

journal_title：Brain research

authors： Tilders FJ,van der Woude HA,Swaab DF,Mulder AH

更新日期：1979-08-10 00:00:00

abstract：:The time-course of intracellular glutathione (GSH) values after incubation with L-buthionine-(S,R)-sulfoximine (BSO), a selective inhibitor of gamma-glutamylcysteine synthetase, showed that glutathione turns over with a half-life of 5 h. Intracellular GSH was assayed by flow cytometry using three different methods. As...

journal_title：Brain research

authors： Devesa A,O'Connor JE,Garciá C,Puertes IR,Viña JR

更新日期：1993-08-06 00:00:00

abstract：:Until now, there has been no effective therapy for chronic sensorineural hearing impairment. This study investigated the role of bone marrow cells (BMCs) in cochlear dysfunction. BALB/c mice (2 months of age), a non-presbycusis-prone mouse strain, were lethally irradiated and then transplanted with BMCs from SAMP1 mic...

journal_title：Brain research

authors： Baba S,Iwai H,Inaba M,Kawamoto K,Omae M,Yamashita T,Ikehara S

更新日期：2006-11-20 00:00:00

abstract：:Delta-9-tetrahydrocannabinol (Delta(9)-THC), the main psychoactive component of marijuana, is known to dysregulate various immune responses. Cannabinoid (CB)-1 and -2 receptors are expressed mainly on cells of the central nervous system (CNS) and the immune system. The CNS is the primary target of cannabinoids and ast...

journal_title：Brain research

authors： Bindukumar B,Mahajan SD,Reynolds JL,Hu Z,Sykes DE,Aalinkeel R,Schwartz SA

更新日期：2008-01-29 00:00:00

abstract：:The origin of the afferents of the thalamic anterior paraventricular and parataenial nuclei (PVA-PT) in the rat was studied with fluorescent retrograde tracing method. After iontophoretic application of Fluoro-Gold into PVA-PT, many labeled cells were found in the medial frontal cortex, ventral subiculum, claustrum, s...

journal_title：Brain research

authors： Chen S,Su HS

更新日期：1990-07-02 00:00:00

abstract：:(1) Spreading depression (SD) could be elicited in isolated carp retina by KCI application, the concomitants of which were similar to those described in other vertebrates. (2) The threshold for generating SD was greatly reduced by brief immersion of the retina in low ci-ringer's solutions. The properties of SD waves w...

journal_title：Brain research

authors： Higashida H,Sakakibara M,Mitarai G

更新日期：1977-01-14 00:00:00

abstract：:Invasion of scrapie agent into the central nervous system (CNS) was studied in rats following intracerebral and peripheral inoculation, the latter by injection into intact or transected sciatic nerve. Comparison of sleep-wakefulness alterations, neuropathological features, and time lag of electroencephalographic and c...

journal_title：Brain research

authors： Bassant MH,Baron H,Gumpel M,Cathala F,Court L

更新日期：1986-09-24 00:00:00

abstract：:In this study we investigated the functional connectivity in 23 Mild TBI (mTBI) patients with and without memory complaints using resting state fMRI in the sub-acute stage of injury as well as a group of control participants. Results indicate that mTBI patients with memory complaints performed significantly worse than...

journal_title：Brain research

authors： Sours C,Zhuo J,Janowich J,Aarabi B,Shanmuganathan K,Gullapalli RP

更新日期：2013-11-06 00:00:00

abstract：:To determine the effect of thyroid hormones (TH) on cerebral tissue malondialdehyde (MDA) content and accumulation of MDA-bound proteins, hyperthyroid rats and hypothyroid rats were compared to euthyroid controls. Hyperthyroidism was induced by daily injection of l-3,5, 3'-triiodothyronine (15 ug (100 g)-1) intraperit...

journal_title：Brain research

authors： Chehade J,Kim J,Pinnas JL,Mooradian AD

更新日期：1999-05-22 00:00:00

abstract：:The purpose of this study is to reveal whether the application of immunohistochemical examinations to the peripheral nervous system (PNS) can be a reliable method for the quantitative analysis of the blood-nerve barrier (BNB) and the relationship between restoration of BNB and nerve regeneration. Sciatic nerves in rat...

journal_title：Brain research

authors： Omura K,Ohbayashi M,Sano M,Omura T,Hasegawa T,Nagano A

更新日期：2004-03-19 00:00:00

abstract：:Ultrastructural examination of the region near the olfactory epithelial surface of leopard frogs revealed the presence of nerve terminals just proximal to the zonula adherens between adjacent sustentacular cells, and between sustentacular cells and olfactory receptor neurons. Terminal varicosities, located about 20 nm...

journal_title：Brain research

authors： Zielinski BS,Getchell ML,Getchell TV

更新日期：1989-07-17 00:00:00

abstract：:The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...

journal_title：Brain research

authors： Ault B,Caviedes P,Rapoport SI

更新日期：1989-04-17 00:00:00

abstract：:The blood-nerve barrier consists of continuous layers of cells linked by tight junctions and includes the endothelial cells which line the endoneurial capillaries and the perineurial cells which surround fascicles of nerve fibers. A facilitated transport carrier protein allows D-glucose to penetrate the barrier. To de...

journal_title：Brain research

authors： Gerhart DZ,Drewes LR

更新日期：1990-01-29 00:00:00

abstract：:We assessed muscarinic M(1), M(2) and M(4) receptor subtypes in the hippocampus of Alzheimer's and control brains by receptor autoradiography using ligands such as [(125)I]muscarinic toxin-1 ([(125)I]MT-1, M(1) selective), [(3)H]AFDX-384 (M(2) partially selective) and [(125)I]muscarinic toxin 4 ([(125)I]M(4) toxin-1, ...

journal_title：Brain research

authors： Mulugeta E,Karlsson E,Islam A,Kalaria R,Mangat H,Winblad B,Adem A

更新日期：2003-01-17 00:00:00

abstract：:Little is known about putative transmitters in the nucleus ambiguus (NA) mediating parasympathetic control of the heart, although Met-enkephalin (m-ENK), Leu-enkephalin (l-ENK), substance P (SP) and acetylcholine (Ach) have been detected in the cell bodies and fibers of this nucleus. The effects of these substances on...

journal_title：Brain research

authors： Agarwal SK,Calaresu FR

更新日期：1991-11-01 00:00:00

abstract：:Spreading depression (SD) is characterized by a transient breakdown of neuronal function concomitant with a massive failure of ion homeostasis. It is a phenomenon that can be induced in neocortical tissue by raising excitability, e.g. injection of K(+), application of glutamatergic agonists, or blocking Na(+)/K(+) ATP...

journal_title：Brain research

authors： Köhling R,Koch UR,Hagemann G,Redecker C,Straub H,Speckmann EJ

更新日期：2003-06-13 00:00:00

abstract：:We examined the effects of early epileptiform activity on development of visuocortical receptive fields in the rabbit. Aqueous penicillin was injected twice a day into a cannula implanted over the monocular area of one visual cortex. Drug administration was begun on postnatal day 8-9 and continued until postnatal day ...

journal_title：Brain research

authors： Crabtree JW,Chow KL,Ostrach LH,Baumbach HD

更新日期：1981-04-01 00:00:00

abstract：:Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling pathways to be studied in their biological context. Here, we demonstrate activity-induced plasticity at neuromuscular synapses of Drosophila double mutant for comatose (an NSF mutant) and Kum (a SERCA mutant), and presen...

journal_title：Brain research

authors： Freeman A,Bowers M,Mortimer AV,Timmerman C,Roux S,Ramaswami M,Sanyal S

更新日期：2010-04-22 00:00:00

abstract：:We have examined, at the light microscope level, putative direct synaptic interconnections, via motor axon collaterals, between type-identified triceps surae alpha-motoneurons labeled by intracellular injection of HRP. The results indicate that monosynaptic recurrent contacts can occur between synergist motoneurons (i...

journal_title：Brain research

authors： Cullheim S,Lipsenthal L,Burke RE

更新日期：1984-08-06 00:00:00

abstract：:The effect of serotonin agonists on the rhythmic excretion of the melatonin metabolite 6-sulphatoxymelatonin was examined in rats. The animals were maintained in 12L:12D and administered saline, quipazine (10 mg/kg), (+/-)-2-propylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide (8-OH-DPAT, 5 mg/kg) or buspi...

journal_title：Brain research

authors： Kennaway DJ,Rowe SA,Ferguson SA

更新日期：1996-10-21 00:00:00