The amiloride-sensitive Na+/H+ exchange antiporter and control of intracellular pH in hippocampal brain slices.

abstract：:Behavioral studies have shown that the hyperalgesia arising from inflammatory agents, such as prostaglandin E(2) (PGE(2)), can be antagonized by activators of the ATP-sensitive potassium current (K(ATP)). This observation raises questions as to whether this suppression results from a direct action on sensory neurons a...

journal_title：Brain research

authors： Chi XX,Jiang X,Nicol GD

更新日期：2007-05-11 00:00:00

abstract：:Size matched male green anoles (Anolis carolinensis) were paired in a neutral setting and allowed to engage in aggressive displays. Winners and losers were apparent in each pair within 90min, resulting in stable dominant/subordinate dyads. Androgen receptor (AR) expression was assessed at three time points after the i...

journal_title：Brain research

authors： Hattori T,Wilczynski W

更新日期：2014-09-25 00:00:00

abstract：:A transplantable mouse testicular teratoma (OTT 6050) which displays a spectrum of neuroepithelial differentiation was evaluated biochemically for concentrations of cyclic AMP (cAMP), serotonin (5-HT), and enzymes involved in the metabolism of the biogenic amines and acetylcholine. These values were compared between t...

journal_title：Brain research

authors： Orenberg EK,Vandenberg SR,Barchas JD,Herman MM

更新日期：1976-01-16 00:00:00

abstract：:The particular vulnerability of hippocampal CA3/CA4 neurons to intracerebroventricularly administered kainate did not occur in rats until postnatal day 16. Glutamate applied in the same way failed to show comparable neurodegenerative signs, even when administered in large doses to adult animals. Alternatively, both ka...

journal_title：Brain research

authors： Wolf G,Keilhoff G

更新日期：1984-05-01 00:00:00

abstract：:Cerebral vascular density is correlated with metabolic demands, which increase in highly active brain areas. External inputs are an essential requirement in the modeling of the visual cortex. Experience-mediated development is very active during the first postnatal month, when congruous blood supply is needed. We stud...

journal_title：Brain research

authors： Argandoña EG,Lafuente JV

更新日期：2000-02-07 00:00:00

abstract：:This study shows that in the choroid plexus of Rana esculenta particulate guanylate cyclase (GC) is appreciably stimulated by porcine brain natriuretic peptide (BNP). Ultracytochemical tests for GC show that BNP notably increases the enzymatic reaction product along the apical surfaces of the epithelial cells. It can ...

journal_title：Brain research

authors： Vagnetti D,Tei S,Secca T,Santarella B,Roscani C,Farnesi RM

更新日期：1995-12-24 00:00:00

abstract：:Cocaine was injected intravenously to non-anesthetized, freely moving adult male rats and caused dose-dependent elevations in plasma adrenocorticotropin (ACTH) levels. The observation that this stimulatory effect was completely abolished by pretreatment with a corticotropin-releasing factor (CRF) antiserum, coupled wi...

journal_title：Brain research

authors： Rivier C,Vale W

更新日期：1987-10-06 00:00:00

abstract：:Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the eve...

journal_title：Brain research

authors： Durukan Tolvanen A,Tatlisumak E,Pedrono E,Abo-Ramadan U,Tatlisumak T

更新日期：2017-05-15 00:00:00

abstract：:We observed chronological changes of platelet endothelial cell adhesion molecule-1 (PECAM-1), final mediator of neutrophil transendothelial migration, immunoreactivity, and protein level in the gerbil hippocampus proper after 5 min of transient ischemia. One day after ischemic insult, PECAM-1 immunoreactivity and prot...

journal_title：Brain research

authors： Hwang IK,Kim DW,Yoo KY,Jung BK,Song JH,Jung JY,Choi SY,Kang TC,Lee JY,Kwon YG,Won MH

更新日期：2005-06-28 00:00:00

abstract：:Neural correlates of conscious awareness can be comfortably studied when awareness of the target stimuli is a varying dependent variable in the experimental conditions where the key independent variables are kept invariant. We presented vernier targets backward masked by an invariant grating with invariant SOA. EEG da...

journal_title：Brain research

authors： Aru J,Bachmann T

更新日期：2009-05-19 00:00:00

abstract：:The technique of intracellular recording was used to assess the effect of SR 31742A, a selective sigma receptor ligand, on N-methyl-d-aspartate (NMDA) and (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated responses in pyramidal cells of the rat medial prefrontal cortex in vitro br...

journal_title：Brain research

authors： Liang X,Wang RY

更新日期：1998-10-05 00:00:00

abstract：:Effects of iontophoretically applied dopamine were investigated in prefrontal neurons of the monkey which showed activity changes during a visual reaction time task. The task consisted of an initial waiting phase (3.0 s), a warning phase (green lamp, 1.5-3.5 s), a lever-release GO phase (red lamp) and a reward phase. ...

journal_title：Brain research

authors： Sawaguchi T,Matsumura M,Kubota K

更新日期：1986-04-23 00:00:00

abstract：:The phenomenon of unidirectional non-cross tolerance (UNCT) to etorphine was observed in adult male rats tolerant to morphine. Using a morphine pellet (four 75 mg morphine pellets) implantation protocol, a 10-fold increase in the analgesic ED50 value, obtained by tail-flick assay, was observed for morphine sulfate, wi...

journal_title：Brain research

authors： Roerig SC,Fujimoto JM,Franklin RB,Lange DG

更新日期：1985-02-18 00:00:00

abstract：:The pyrithiamine-treated rats produced by our method histopathologically exhibited the edematous lesion not only around the third ventricle and at the tegmentum of pons, as expected, but also in the cerebral cortex. These animals were, therefore, used in a biochemical study of the cerebral cortex, in particular, gluco...

journal_title：Brain research

authors： Takahashi H,Nakazawa S,Yoshino Y,Shimura T

更新日期：1988-02-16 00:00:00

abstract：:Embryonic day 15 rostral tectum (presumptive superior colliculus) was transplanted into the occipital cortex of newborn rats. One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After the appropriate surv...

journal_title：Brain research

authors： Sharkey MA,Steedman JG,Lund RD,Dom RM

更新日期：1987-01-01 00:00:00

abstract：:The olivary pretectal nucleus is a primary visual centre sensitive to luminance changes. It is involved in the pupillary light reflex, the consensual pupillary light reflex and related reflexes, such as the lid closure reflex whereby pupillary constriction takes place. Since the olivary pretectal nucleus is a small nu...

journal_title：Brain research

authors： Klooster J,Vrensen GF,Müller LJ,van der Want JJ

更新日期：1995-08-07 00:00:00

abstract：:Serotonin (5HT) is thought to reset the biological clock in the suprachiasmatic nuclei (SCN) in vitro through a postsynaptic 5HT-1a receptor. Thus we examined 5HT receptor gene expression in the SCN by in situ hybridization. On film autoradiograms, 5HT-1c receptor mRNA showed intense SCN hybridization, while 5HT-1b re...

journal_title：Brain research

authors： Roca AL,Weaver DR,Reppert SM

更新日期：1993-04-09 00:00:00

abstract：:Elevated levels of lactic acid can be deleterious to CNS tissue. Lactic acid is known to cause astroglial swelling and since glial swelling has been shown to inhibit L-glutamate (L-Glu) uptake, we examined whether one of the actions of lactic acid is to inhibit L-Glu uptake. Astrocyte cultures treated with lactic acid...

journal_title：Brain research

authors： Bender AS,Young LP,Norenberg MD

更新日期：1997-03-07 00:00:00

abstract：:It has been suggested that thiolic groups are essential for cytochrome c oxidase (COX) activity and other respiratory mitochondrial enzymes. Recent experiments showed that the thiolic antioxidant N-acetylcysteine (NAC) can protect against age-related impairment in COX activity in mice hepatic mitochondria. The present...

journal_title：Brain research

authors： Martínez Banaclocha M,Martínez N

更新日期：1999-09-18 00:00:00

abstract：:Metabolites formed from testosterone in the brain, their neuroanatomical distribution and the kinetic properties of the enzymes were studied in male and female Japanese quail chicks and compared with the adult brain using an in vitro radioassay. Oestradiol-17 beta. 5 alpha-dihydrotestosterone, 5 beta-dihydrotestostero...

journal_title：Brain research

authors： Hutchison JB,Schumacher M

更新日期：1986-02-01 00:00:00

abstract：:Neonatal (postnatal days 8-21) exposure of rats to the selective serotonin reuptake inhibitor (SSRI), citalopram, results in persistent changes in behavior including decreased sexual activity in adult animals. We hypothesized that this effect was a consequence of abnormal stimulation of 5-HT(1A) and/or 5-HT(1B) recept...

journal_title：Brain research

authors： Maciag D,Coppinger D,Paul IA

更新日期：2006-12-13 00:00:00

abstract：:We investigated the influence of muramyl dipeptide (MDP), a cell wall component of Gram-positive bacteria, on cytokine-induced nitric oxide (NO) production in rat primary astrocytes. MDP alone did not induce NO release in astrocyte cultures. However, MDP increased astrocyte NO production and subsequent nitrite accumul...

journal_title：Brain research

authors： Trajkovic V,Samardzic T,Stosic-Grujicic S,Ramic Z,Mostarica Stojkovic M

更新日期：2000-11-10 00:00:00

abstract：:Voltage-gated potassium (Kv) channels are essential components of neuronal excitability. The Kv3.4 channel protein is widely distributed throughout the central nervous system (CNS), where it can form heteromeric or homomeric Kv3 channels. Electrophysiological studies reported here highlight a functional role for this ...

journal_title：Brain research

authors： Dallas ML,Morris NP,Lewis DI,Deuchars SA,Deuchars J

更新日期：2008-01-16 00:00:00

abstract：:Previous work has shown that bilateral injection of as little as 10 microgram of cycloheximide (CHX) into the amygdala, but not into the internal capsule, caused a time-dependent disruption of long-term retention of passive avoidance training. Under these conditions, protein synthesis in the entire brain was inhibited...

journal_title：Brain research

authors： Kesner RP,Partlow LM,Bush LG,Berman RF

更新日期：1981-03-23 00:00:00

abstract：:Potassium-evoked cholecystokinin (CCK) release from slices of caudate-putamen and cerebral cortex, but not hippocampus incubated in vitro was increased by 152-175% by preincubation for 40 min with 10 mM lithium. These results and previous studies suggest that although different physiological agents regulate CCK releas...

journal_title：Brain research

authors： Gysling K,Allard LR,Beinfeld MC

更新日期：1987-06-16 00:00:00

abstract：:Recent radioligand binding studies demonstrated an increase in the density of dopamine D2 receptors in the nucleus accumbens ipsilateral to the stimulating electrode in amygdala- or hippocampal-kindled rats. In the present study we examined the anticonvulsant effect of dopamine agonists by unilateral microinjections i...

journal_title：Brain research

authors： Wahnschaffe U,Löscher W

更新日期：1991-07-12 00:00:00

abstract：:Embryonic cortex from 19-day fetuses was transplanted in a medial frontal cortex wound cavity of 105-day-old male rats. Nissl-stained tissue revealed little internal laminar organization. Graft sections impregnated by the Loyez method exhibited bands of myelinated fibers surrounding implants as well as long-interconne...

journal_title：Brain research

authors： Mufson EJ,Labbe R,Stein DG

更新日期：1987-01-13 00:00:00

abstract：:Development and aging are often mirror image processes and this may be equally true in the effects of estradiol, a potent endogenous steroid regulating brain development as well as a therapeutic used to relieve the negative components of perimenopause. Both the developing and perimenopausal brain are characterized by ...

journal_title：Brain research

authors： McCarthy MM

更新日期：2011-03-16 00:00:00

abstract：:The spinal cord dorsal horn contains neural mechanisms which can greatly facilitate pain. We have recently shown that 'illness'-inducing agents, such as intraperitoneally administered lipopolysaccharide (LPS; bacterial endotoxin), can produce prolonged hyperalgesia. This hyperalgesic state is mediated at the level of ...

journal_title：Brain research

authors： Watkins LR,Wiertelak EP,Furness LE,Maier SF

更新日期：1994-11-21 00:00:00

abstract：:It was previously proposed that norepinephrine (NE)-containing nerve terminals in visual cortex are important for the maintenance of cortical plasticity. Observations at that time indicated that local microperfusion of exogenous NE for 1 week directly into kitten visual cortex, with no alteration of the visual environ...

journal_title：Brain research

authors： Kuppermann BD,Kasamatsu T

更新日期：1984-06-04 00:00:00