Abstract:
:A 58-year-old woman who suffered from a heterozygous Fabry's disease and immune complex crescentic glomerulonephritis (GN) is reviewed. The diagnosis was made on the basis of the pathologic findings and peripheral leukocyte alpha-galactosidase activity. Light microscopy revealed a vacuolization of epithelial cells and electron microscopy showed myelin figures in the cytoplasm of visceral epithelial cells typical of Fabry's disease at the first renal biopsy. During the following 4 months she developed progressive renal failure and a second renal biopsy disclosed the formation of cellular crescents in 7 of 11 glomeruli observed. A rare case of combined Fabry's disease and crescentic glomerulonephritis is discussed.
journal_name
Nephronjournal_title
Nephronauthors
Shimazu K,Tomiyoshi Y,Aoki S,Sakemi T,Sugihara Hdoi
10.1159/000063287subject
Has Abstractpub_date
2002-10-01 00:00:00pages
456-8issue
2eissn
1660-8151issn
2235-3186pii
63287journal_volume
92pub_type
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